PQG Seminar Series

The PQG will host another monthly seminar series for the 2014-2015 school year. Please see the full list of dates and speakers below, as they continue to be updated.

The goal of the PQG Seminar Series is to encourage the exchanging of ideas, promote interaction, collaboration, and research in quantitative genomics. It also aims to promote the mission of the PQG which is to improve health through an interdisciplinary study of genetics, behavior, environment and medicine. The seminar series looks to include the development and application of quantitative methods, especially for high dimensional data, as well as a focus on the training of quantitative genomic scientists.

Please direct any logistical questions to Shaina Andelman at sandelma@hsph.harvard.edu

Upcoming Seminar


Tuesday, December 9, 2014
12:30-2:00 PM
Kresge G2

a pizza lunch will be provided

Brian Browning
Associate Professor
Department of Medicine, Division of Medical Genetics
University of Washington

Haplotype frequency models: what they are and why they matter

Haplotype frequency models are used to estimate the population frequency of a sequence of alleles at tightly-linked loci. These models are used in a wide variety of genetic analyses because they enable analyses to use information from correlated, closely-spaced variants. This talk will describe a new haplotype frequency model that that uses relatedness to reduce computational complexity. The new model uses the same graphical model as the Beagle haplotype frequency model, but unlike the original Beagle model, the new model incorporates genetic recombination, genotype error, and identity by descent. We can use this model to estimate haplotypes from unphased genotype data. The new model produces more accurate haplotypes than existing methods, and it requires substantially less computation time than the most accurate existing method.

2014-2015 Seminar Schedule


  • Tuesday, September 16, 2014
    12:30-2:00 PM
    Kresge G2
    Soumya Raychaudhuri, Harvard Medical School
  • Tuesday, October 14, 2014
    12:30-2:00 PM
    Kresge G2
    Hongzhe Li, University of Pennsylvania

  • Tuesday, November 4, 2014
    12:30-2:00 PM
    Kresge G2
    Molly Przeworski, Columbia University

  • Tuesday, December 9, 2014
    12:30-2:00 PM
    Kresge G2
    Brian Browning, University of Washington


  • Tuesday, January 27, 2015
    12:30-2:00 PM
    Kresge G2
    Christopher Amos, Dartmouth Medical School

  • Tuesday, February 10, 2015
    12:30-2:00 PM
    Kresge G2
    Daniel MacArthur, Massachusetts General Hospital

  • WEDNESDAY, March 11, 2015
    12:30-1:30 PM
    FXB G13

    Gad Getz, The Broad Institute

  • Tuesday, March 31, 2015
    12:30-2:00 PM
    Kresge G2
    David Altshuler, The Broad Institute

  • Tuesday, April 14, 2015
    12:30-2:00 PM
    Kresge G2
    Hua Tang, Stanford University

  • Tuesday, May 5, 2015
    12:30-2:00 PM
    FXB G12
    Steve Horvath, UCLA




Seminar Archive