COURSE INFORMATION
Alphabetic Listing

 
 
 

BIO111 Introduction to Programming in SAS
WinterSession
Dr. T. Fenton

1.25 credits
Lectures and Laboratories. Six 4-hour sessions combining both.

Provides an overview in the use of SAS to prepare data for statistical analysis. The focus is on database management and programming problems. Basic issues in each of these areas are discussed in the context of introducing the specific skills required to use SAS effectively.
Course Note: Credit is given for only one of BIO 111 or BIO 113; The course meets January 6, 7, 8, 13, 14, 15.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO113 Introduction to Data Management and Programming in SAS
Fall 1
Ms. L. Allred

2.5 credits
Lectures, laboratories. Two 2-hour sessions each week. Two 1-hour lab each week.

Provides intensive instruction in the use of SAS to prepare data for statistical analysis. The focus is on database management and programming problems. Basic issues in each of these areas are discussed in the context of teaching the specific skills required to use SAS effectively.
Course Note: Credit is given for only one of BIO 111 or BIO 113; BIO 200, BIO 201, or BIO 202 and BIO 203, or signature of instructor required; lab time follows each course session for one hour.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO200 Principles of Biostatistics
Fall
Dr. D. Harrington

5 credits
Lectures, laboratories. Two 1-hour sessions each week. One 2-hour lab each week.

Lectures and laboratory exercises acquaint the student with the basic concepts of biostatistics and their applications and interpretation. The computer is used throughout the course. Topics include descriptive statistics, graphics, diagnostic tests, probability distributions, inference, tests of significance, association, linear and logistic regression, life tables, and survival analysis.
Course Note: Credit is given for only one of BIO 200, BIO 201; this course cannot be counted as part of the credit requirement for a major or minor doctoral field course; course restricted to students not eligible for BIO 201. Other students allowed with signature of course instructor, if space permits; course enrollment is limited to 150 students; lab or section times to be announced at first meeting. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO200R Principles of Biostatistics Repeat
Spring
Dr. D. Wypij

2.5 credits
Independent Study

Open only to students who have failed the core course, and must repeat it. Students must sign up for the section with the instructor from whom they took the original course.
Course Note: Completed independent study contract is required at the time of registration; pass/fail only; signature of instructor required.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO200R Principles of Biostatistics Repeat
Fall
Dr. D. Wypij

2.5 credits
Independent Study

Open only to students who have failed the core course, and must repeat it. Students must sign up for the section with the instructor from whom they took the original course.
Course Note: Completed independent study contract is required at the time of registration; pass/fail only; signature of instructor required.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO201 Introduction to Statistical Methods
Fall
Dr. K. Gauvreau

5 credits
Lectures, laboratories. Two 1.5-hour sessions each week. One 2-hour lab each week.

Covers basic statistical techniques that are important for analyzing data arising from epidemiology, environmental health and biomedical and other public health-related research. Major topics include descriptive statistics, elements of probability, introduction to estimation and hypothesis testing, nonparametric methods, techniques for categorical data, regression analysis, analysis of variance, and elements of study design. Applications are stressed. Designed as an alternate to BIO200, for students desiring more emphasis on theoretical developments. Background in algebra and calculus strongly recommended.
Course Note: Credit is given for only one of BIO200 or BIO201; this course cannot be counted as part of the credit requirement for a major or minor doctoral field course; course restricted to students enrolled in DBS, EH, EPI, NUT, MPH/QM programs, and SHDH doctoral students. Other students allowed with signature of course instructor if space permits; lab or section times to be announced at first meeting.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO201R Introduction to Statistical Methods
Spring
Dr. K. Gauvreau

2.5 credits
Independent Study

Open only to students who have failed the core course, and must repeat it. Students must sign up for the section with the instructor from whom they took the original course.
Course Note: Completed independent study contract is required at the time of registration; pass/fail only; signature of instructor required.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO202 Principles of Biostatistics I
Summer 1
Dr. M. Testa

2.5 credits
Lectures, laboratories. Five 2-hour sessions and five 2-hour labs each week.

This course is the first part of introductory biostatistics and acquaints the student with the basic concepts and methods of biostatistics, their applications, and their interpretation. The material covered includes data presentation, numerical summary measures, rates and standardization, and life tables. Probability is introduced to quantify uncertainty, especially as it pertains to diagnostic and screening methods. Also covered are sampling distributions so that students may be introduced to confidence intervals and hypothesis testing. The computer is used throughout the c ourse, and the student will gain familiarity with the software package STATA.
Course Note: Requires a basic knowledge of mathematics and familiarity with use of personal computers. Students taking BIO202 and BIO203 will not be given credit for BIO200 or BIO201. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO203 Principles of Biostatistics II
Summer 2
Dr. B. Healy

2.5 credits
Lectures, laboratories. Five 2-hour sessions each week and five 2-hour labs each week.

This course is the second part of introductory biostatistics; it continues to explore inference in greater depth. Lectures and laboratory exercises will emphasize applied data analysis, building upon the fundamentals emphasized in BIO 202. Topics covered include the comparison of two means, analysis of variance, non-parametric methods, inference on proportions, contingency tables, multiple 2 X 2 tables, correlation, simple regression, multiple regression and logistic regression, analysis of survival data, and sampling theory. The computer is used throughout the course, and the student will gain more familiarity with STATA.
Course Note: BIO 202 is required; Students who take BIO202 and BIO 203 will not be given credit for BIO200 or BIO201. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO206 Introductory Statistics for Medical Research
Summer 1
Dr. E. J. Orav

2.5 credits
Lectures. Five 2-hour sessions each week.

Introduces basic biostatistical techniques with an emphasis on applications to clinical research. Topics include probability and
statistics, hypothesis testing, confidence intervals, non-parametrics, and power calculations.
Course Note: Designed primarily for participants in the Program in Clinical Effectiveness; no auditors. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO207 Statistics for Medical Research II
Summer 2
Dr. G. Reed (P), Dr. E.J. Orav (S)

2.5 credits
Lectures. Five 2-hour sessions each week.

Presents additional biostatistical techniques that commonly appear in the analysis of clinical databases and trials. Topics include contingency table analyses, log-rank tests, paired and matched analyses, analysis of variance and multiple comparisons procedures.
Course Note: BIO 206 required; no auditors. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO208 Statistics for Medical Research, Advanced
Summer 2
Dr. E. J. Orav

2.5 credits
Lectures. Five 2-hour sessions each week.

Presents additional biostatistical techniques that commonly appear in the analysis of clinical databases and trials. This course will move at a faster pace than the alternative BIO 207 while covering all of the same topics (contingency tables, log-rank tests, paired and matched analyses, analysis of variance and multiple comparisons procedures). In addition, linear and logistic regression will be introduced.
Course Note: BIO 206 required; no auditors. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO209 Statistics for Medical Research, Translational
Summer 2
Dr. K. Nelson

2.5 credits
Lectures. Five 2-hour sessions each week.

Presents additional biostatistical techniques that are most relevant to researchers involved with designed experiments. Topics include contingency tables, paired analyses, simple analysis of variance, multiple comparisons procedures, two-way analysis of variance, and simple repeated measures analysis of variance.
Course Note: BIO 206 required; no auditors.



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO210 The Analysis of Rates and Proportions
Spring
Dr. R. Glynn

5 credits
Lectures, laboratories. Two 1.5-hour sessions each week. One 1.5-hour lab each week.

Emphasizes concepts and methods for analysis of data which are categorical, rate-of-occurrence (e.g., incidence rate), and time-to-event (survival duration). Stresses applications in epidemiology, clinical trials, and other public health research. Topics include measures of association, 2x2 tables, stratification, matched pairs, logistic regression, model building, analysis of rates, and survival data analysis using proportional hazards models.
Course Note: BIO 200, or BIO 201, or BIO 202 and BIO 203, or BIO 206 and one of BIO 207, BIO 208, or BIO 209, or signature of instructor required; lab or section times to be announced at first meeting. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO210 The Analysis of Rates and Proportions
Fall
Dr. B. Rosner

5 credits
Lectures, laboratories. Two 1.5-hour sessions each week. One 1.5-hour lab each week.

Emphasizes concepts and methods for analysis of data which are categorical, rate-of-occurrence (e.g., incidence rate), and time-to-event (survival duration). Stresses applications in epidemiology, clinical trials, and other public health research. Topics include measures of association, 2x2 tables, stratification, matched pairs, logistic regression, model building, analysis of rates, and survival data analysis using proportional hazards models.
Course Note: BIO 200, or BIO 201, or BIO 202 and BIO 203, or BIO 206 and one of BIO 207, BIO 208, or BIO 209, or signature of instructor required; lab or section times to be announced at first meeting. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO211 Regression and Analysis of Variance in Experimental Research
Fall
Dr. P. Catalano

5 credits
Lectures, laboratories. Two 1.5-hour sessions each week; one 1-hour lab each week.

Covers analysis of variance and regression, including details of data-analytic techniques and implications for study design. Also included are probability models and computing. Students learn to formulate a scientific question in terms of a statistical model, leading to objective and quantitative answers.
Course Note: BIO 200, or BIO 201, or BIO 202 and BIO 203, or BIO 206 and one of BIO 207, BIO 208, or BIO 209, or signature of instructor required; lab or section times to be announced at first meeting.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO212 Survey Research Methods In Community Health
Spring
Dr. T. Mangione (P), Dr. L. Ryan (S)

2.5 credits
Lectures. One 2-hour session each week.

Covers research design, sample selection, questionnaire construction, interviewing techniques, the reduction and interpretation of data, and related facets of population survey investigations. Focuses primarily on the application of survey methods to problems of health program planning and evaluation. Treatment of methodology is sufficiently broad to be suitable for students who are concerned with epidemiological, nutritional, or other types of survey research. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO213 Applied Regression for Clinical Research
Fall
Dr. E. J. Orav

5 credits
Lectures. Two 2-hour sessions each week. One 1.5-hour lab each week.

This course will introduce students involved with clinical research to the practical application of multiple regression analysis. Linear regression, logistic regression and proportional hazards survival models will be covered, as well as general concepts in model selection, goodness-of-fit, and testing procedures. Each lecture will be accompanied by a data analysis using SAS and a classroom discussion of the results. The course will introduce, but will not attempt to develop the underlying likelihood theory. Background in SAS programming ability required.
Course Note: BIO 200, or BIO 201, or BIO 202 and BIO 203, or BIO 206 and one of BIO 207, BIO 208, or BIO 209, or signature of instructor required; lab or section times to be announced at first meeting. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO214 Principles of Clinical Trials
Spring 1
Dr. J. Ware

2.5 credits
Lectures. Two 2-hour sessions each week.

Designed for individuals interested in the scientific, policy, and management aspects of clinical trials. Topics include types of clinical research, study design, treatment allocation, randomization and stratification, quality control, sample size requirements, patient consent, and interpretation of results. Students design a clinical investigation in their own field of interest, write a proposal for it, and critique recently published medical literature.
Course Note: BIO 200, or BIO 201, or BIO202 and BIO203, or BIO206 and one of BIO 207, BIO 208 or BIO 209, or signature of instructor required. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO214 Principles of Clinical Trials
Summer 2
Dr. K. Stanley, Dr. R. Gelber

2.5 credits
Lectures. Five 2-hour sessions each week.

Designed for individuals interested in the scientific, policy, and management aspects of clinical trials. Topics include types of clinical research, study design, treatment allocation, randomization and stratification, quality control, sample size requirements, patient consent, and interpretation of results. Students design a clinical investigation in their own field of interest, write a proposal for it, and critique recently published medical literature.
Course Note: Signature of instructor required. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO222 Basics of Statistical Inference
Fall
Dr. P. Williams

5 credits
Lectures, laboratories. Two 1.5 hour-sessions each week. One 2-hour lab each week.

This course will provide a basic, yet thorough introduction to the probability theory and mathematical statistics that underlie many of the commonly used techniques in public health research. Topics to be covered include probability distributions (normal, binomial, Poisson), means, variances and expected values, finite sampling distributions, parameter estimation (method of moments, maximum likelihood), confidence intervals, hypothesis testing (likelihood ratio, Wald and score tests). All theoretical material will be motivated with problems from epidemiology, biostatistics, environmental health and other public health areas. This course is aimed towards second year doctoral students in fields other than Biostatistics. Background in algebra and calculus required.
Course Note: One intermediate level biostatistics course such as BIO 210, or BIO 211, or signature of the instructor required; lab or section times to be announced at first meeting. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO223 Applied Survival Analysis
Spring
Dr. Lee-Jen Wei

5 credits
Lectures. Two 2-hour sessions each week. One 1-hour optional lab each week.

This course will cover topics in both discrete data analysis (25% of class) and applied survival analysis (75% of class). The course will begin with a review of sampling plans and contingency table for discrete data. Further topics in discrete data analysis will include logistic regression, exact inference, and conditional logistic regression. This short survey of discrete data topics will provide a natural transition to analysis of survival data. Survival topics include: hazard, survivor, and cumulative hazard functions, Kaplan-Meier and actuarial estimation of the survival distribution, comparison of survival using log rank and other tests, regression models including the Cox proportional hazards model and accelerated failure time model, adjustment for time-varying covariates, and use of parametric distributions (exponential, Weibull) in survival analysis. Class material will include presentation of statistical methods for estimation and testing, along with current software (SAS, Stata, Splus) for implementing analyses of discrete data and survival data. Applications to real data will be emphasized.
Course Note: BIO 210, BIO 213, or BIO 230 required, or signature of instructor.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO224 Survival Methods in Clinical Research
Summer 2
Dr. R. Davis

2.5 credits
Lectures. Five 2-hour sessions each week.

This course will cover the common approaches to the display and analysis of survival data, including Kaplan-Meier curves, log rank tests, and Cox proportional hazards regression. Computing, using SAS, will be an integral component of the course.
Course Note: BIO 210, BIO 211, BIO 213 or signature of instructor required.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO226 Applied Longitudinal Analysis
Spring
Dr. M. Hughes

5 credits
Lectures, laboratories. Two 2-hour sessions each week.

This course covers modern methods for the analysis of repeated measures, correlated outcomes and longitudinal data, including the unbalanced and incomplete data sets characteristic of biomedical research. Topics include an introduction to the analysis of correlated data, analysis of response profiles, fitting parametric curves, covariance pattern models, random effects and growth curve models, and generalized linear models for longitudinal data, including generalized estimating equations (GEE) and generalized linear mixed effects models (GLMMs).

Course Activities: Homework assignments will focus on data analysis in SAS using PROC GLM, PROC MIXED, PROC GENMOD, and PROC NLMIXED.

Course Note: BIO 210, BIO 211, BIO 213, or BIO 232, or signature of instructor required; lab or section times will be announced at first meeting.

Course Evaluations


BIO227 Fundamental Concepts in Gene Mapping
Fall 2
Dr. N. Laird

2.5 Credits
Lectures, laboratories. Two 1.5-hour sessions each week.

This course introduces students to the diverse statistical methods used throughout the process of genetic epidemiology, from familial aggregation and segregation studies to linkage scans candidate-gene association studies. Topics covered include multipoint and model-free linkage analysis, linkage disequilibrium, family-based and population-based association test, and study design. Instructors use ongoing research into the genetics of asthma and cancer to illustrate basic principles. Homework includes analysis projects to familiarity students with state-of-the-art software for linkage analysis, family-based association tests, and case-control studies. Some familiarity with molecular biology and statistical hypothesis testing (e.g. material covered in EPI249 and BIO201) is helpful, although not necessary, as relevant concepts will be reviewed in lectures and labs. Students should leave with a basic understanding of how to read and evaluate statistical studies of genetics epidemiology.

Course Note: Lab or section time will be announced at first meeting.
Course Evaluations


BIO230 Probability Theory and Applications I
Fall
Cross listed at FAS as BIST230

Dr. A. Schwartzman
5 credits
Lectures, laboratories. Two 2-hour sessions each week. One 2-hour lab each week.

Axiomatic foundations of probability, independence, conditional probability, joint distributions, transformations, moment generating functions, characteristic functions, moment inequalities, sampling distributions, modes of convergence and their interrelationships, laws of large numbers, central limit theorem, and stochastic processes.
Course Note: Enrollment in the Biostatistics department, or BIO 222, or signature of instructor required; lab or section times to be announced at first meeting; cross-listed: HSPH student must register for HSPH course.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO231 Statistical Inference I
Spring
Cross-listed as FAS as BIST231

Dr.Y. Li
5 credits
Lectures, laboratories. Two 2-hour sessions each week. One 1.5-hour lab each week.

A fundamental course in statistical inference. Discusses general principles of data reduction: exponential families, sufficiency, ancillarity and completeness. Describes general methods of point and interval parameter estimation and the small and large sample properties of estimators: method of moments, maximum likelihood, unbiased estimation, Rao-Blackwell and Lehmann-Scheffe theorems, information inequality, asymptotic relative efficiency of estimators. Describes general methods of hypothesis testing and optimality properties of tests: Neyman-Pearson theory, likelihood ratio tests, score and Wald tests, uniformly and locally most powerful tests, asymptotic relative efficiency of tests.
Course Note: BIO 230 or signature of instructor required; lab or section time to be announced at first meeting; cross-listed: HSPH student must register for HSPH course.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO232 Methods I
Fall
Cross-listed at FAS as BIST232

Dr. D. Neuberg
5 credits
Lectures. Two 2-hour sessions each week.

Introductory course in the analysis of Gaussian and categorical data. The general linear regression model, ANOVA, robust alternatives based on permutations, model building, resampling methods (bootstrap and jackknife), contingency tables, exact methods, logistic regression.
Course Note: Enrollment in the Department of Biostatistics, or signature of instructor required; lab or section times to be announced at first meeting; cross-listed: HSPH student must register for HSPH course. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO233 Methods II
Spring
Dr. B. Coull

5 credits
Lectures, laboratories (optional). Two 2-hour sessions each week. One 1.5-hour lab each week.

Intermediate course in the analysis of Gaussian, categorical, and survival data. The generalized linear model, Poisson regression, random effects and mixed models, comparing survival distributions, proportional hazards regression, splines and smoothing, the generalized additive model.
Course Note: BIO 232, or signature of instructor required; lab or section times to be announced at first meeting.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO234 Research Synthesis & Meta-Analysis in Public Health & Medicine
Summer 2
Dr. M. Stoto

2.5 credits
Lectures. Five 2-hour sessions each week.

Concerned with the use of existing data to inform clinical decision making and health care policy, the course focuses on research synthesis (meta-analysis). The principles of meta-analytic statistical methods are reviewed and the application of these to data sets is explored. Application of methods includes considerations for clinical trials and observational studies. The use of meta-analysis to explore data and identify sources of variation among studies is emphaiszed, as is the use of meta-analysis to identify future research questions.
Course Activities: Students prepare a protocol to conduct a meta-analysis and use existing meta-analysis software to apply principles outlined in the course to data sets provided for this purpose.
Course Note: This course is equivalent to EPI233; credit will not be given for both courses. (rev. 10.03)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO235 Regression and Analysis of Variance
Fall
Dr. T. Cai

5 credits
Lectures, laboratories. Two 2-hour sessions each week. One 2-hour lab each week.

This is an advanced course in data analysis for linear models - regression and analysis of variance. Estimation methods (maximum likelihood and least squares) and issues of inference (confidence intervals, hypothesis testing, analysis of residuals) are presented from a theoretical and data analysis perspective. Background in matrix algebra and linear regression required.
Course Note: BIO230 and BIO232, or signature of instructor required; lab or section times to be announced at first meeting; cross-listed, HSPH student must register for HSPH course.
(5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO237 Modern Statistical Computing Environments
Fall
Dr. C. Li

5 Credits
Lectures, Laboratroies. Two 1.5-hour session each week.

Acquaints students with statistical computing enviroments under Windows and Linux systems. Taught in a computing lab, the course consists of lectures, demonstrations and hands-on exercises. Example topics include R, SAS, LaTeX, Python, and online resources.

Course Note: Enrollment in a biostatistics or related degree program required; no auditors.

Course Evaluations


BIO238 Advanced Topics in Clinical Trials
Spring 2
TBA

2.5 Credits
Lectures. Two 1.5-hour sessions each week. One 1.5-hour lab each week.

This course will focus on selected advanced topics in the design, analysis, and interpretation of clinical trials, including study design; choice of endpoints (including surrogate endpoints); interim analyses and group sequential methods; subgroup analyses; and meta-analyses.

Course note: BIO214, BIO230, and BIO231 (may be taken concurrently) or signature of instructor required.

Course Evaluations


BIO243 Nonparametric Methods
Spring 1
Dr. M. Hughes

2.5 credits
Course not offered 2008-2009; offered alternate years.
Lectures. Two 2-hour sessions each week.

Presents the theory and application of nonparametric methods. Topics include permutation tests, permutation limit theorems, 2-sample rank tests and their asymptotic efficiency, k-sample rank tests, 1-sample tests of location, paired comparisons, rank tests for symmetry and independence, and analogues of linear modeling based on ranks.
Course Note: BIO231 required.




Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO244 Analysis of Failure Time Data
Spring
Dr. J. Lok

5 credits
Lectures. Two 2-hour sessions each week.

Discusses the theoretical basis of concepts and methodologies associated with survival data and censoring, nonparametric tests, and competing risk models. Much of the theory is developed using counting processes and martingale methods. Material is drawn from recent literature.

Course Note: BIO231 and BIO233 required; cross-listed, HSPH students must register for HSPH course (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO245 Analysis of Multivariate and Longitudinal Data
Spring
Cross-listed at FAS as BIST245

Dr. D. Wypij
5 credits
Lectures. Two 2-hour sessions each week.

Presents classical and modern approaches to the analysis of multivariate observations, repeated measures, and longitudinal data. Topics include the multivariate normal distribution, Hotelling's T2, MANOVA, the multivariate linear model, random effects and growth curve models, generalized estimating equations, statistical analysis of multivariate categorical outcomes, and estimation with missing data. Discusses computational issues for both traditional and new methodologies.

Course Note: BIO231 and BIO235 required; cross-listed, HSPH student must register for HSPH course. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO247 Design of Scientific Investigations
Spring
Cross-listed at FAS as BIST247

Dr. M. Hughes
5 credits
Course Not Offered 2008-2009; offered alternate years.
Lectures. Two 2-hour sessions and one 2-hour lab each week.

Sample size considerations, basic principles of experimental design (randomization, replication, and balance), block designs, factorial experiments, response surface modeling, optimal design, clinical trials, adaptive and sequential designs.
Course Note: BIO 235 or signature of instructor required; minimum enrollment of 10 students required; cross-listed, HSPH student must register for HSPH course. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO248 Advanced Statistical Computing
Spring
Dr. P. Catalano

5 credits
Not Offered 2008-2009.
Lectures. Two 2-hour sessions each week.

A course in computing algorithms useful in statistical research and advanced statistical applications. Topics include computer arithmetic, matrix algebra, numerical optimization ethods with application to maximum likelihood estimation and GEEs, spline smoothing and penalized likelihood, numerical integration, random number generation and simulation methods, Gibbs sampling, bootstrap methods, missing data problems and EM, imputation, data augmentation algorithms, and Fourier transforms. Students should be proficient with C or Fortran programming.
Course Note: BIO235, or signature of instructor required; cross-listed, HSPH student must register for HSPH course. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO249 Bayesian Methods in Biostatistics
Spring
Dr. C. Paciorek

5 credits
Course Not Offered 2009-2010
Lectures. Two 2-hour sessions each week.

General principles of the Bayesian approach, prior distributions, hierarchial models and modeling techniques, approximate inference, Markov chain Monte Carlo methods, model assessment and comparison. Bayesian approaches to GLMMs, multiple testing, nonparametrics, clinical trails, survival analysis.

BIO230 (Probability Theory and Applications I), BIO231 (Statistical Inference I), and BIO232 (Methods I), or the signature of the instructor is required. BIO233 (Methods II) will also be helpful for the second part of the course.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO250 Probability Theory and Applicaitons II
Fall
Dr. R. Gray

5 Credits
Lectures. Two 2-hour sessions each week.

Basic set theory, measure theory, Riemann-Stieltjes and lebesgue integration, conditional probability, conditional expectation (projection), martingales, Randon-Nikodym derivative, product measure and Fubini's Theorem, limit theorems on sequences of random variables, stochastic processes, weak convergence.

Course Note: BIO 230 and BIO 232, or Signature of instructor required.

Course Evaluations


BIO251 Statistical Inference II
Spring
Dr. A. Rotnitzky

5 credits
Lectures. Two 2-hour sessions each week.

Sequel to BIO 231. Considers several advanced topics in statistical inference. Topics include limit theorems, multivariate delta method, properties of maximum likelihood estimators, saddlepoint approximations, asymptotic relative efficiency, robust and rank-based procedures, resampling methods, and nonparametric curve estimation.
Course Note: BIO 231 required; cross-listed, HSPH must register for HSPH course (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO257 Advanced Statistical Genetics
Spring
Dr. N. Laird

5 credits
Lectures, laboratories. One 4-hour sessions each week. One 2-hour lab each week.
Course not offered 2009-2010.

This course concentrates on the statistical aspects of genetic studies for complex-disease, covering both modern linkage and association analysis. The goal is to enable students to read fundamental papers and to engage in original research.

Course Note: BIO 231 and BIO 233, or permission of instructor required. Lab or section times to be announced at first meeting.

Course Evaluations


BIO262 Statistical Problems in Drug Development
Fall
Dr. M. Testa

2.5 credits
Course not offered 2008-2009; offered alternate years.
Lectures. One 2-hour session each week.

This course will introduce the student to the "real life" applications of statistical methodology required for pharmaceutical drug development and will feature guest lecturers from the pharmaceutical industry. Weekly seminars will cover statistical techniques used in the various phases of drug development, including assessment of pharmacologic activity; preclinical animal models and toxicology studies; clinical trials (Phase I dose ranging through Phase III comparative efficacy trials); and post-surveillance, pharmacoepidemiologic and pharmacoeconomic studies. Statistical techniques and examples include applications of optimum screening designs, use of non-parametric estimators, problems of multiplicity, tests for monotonicity, parametric and nonparametric regression, ordered categorical data analysis, survival methods, issues of power and sample size, bioequivalence studies, longitudinal data analysis, univariate and multivariate general linear models, multiple endpoint problems and quality-of-life measurement models. Exposure to
linear models and non-parametric statistics recommended.
Course Note: BIO 210, BIO 211 or BIO 213 or signature of the instructor required. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO263 Computational Methods for Categorical Data Analysis
Spring
Dr. C. Mehta

2.5 credits
Offered alternate years. Not offered 2008-2009
Lectures. One 2-hour sessions each week.

This course deals with exact nonparametric methods of inference. These methods use fast numerical algorithms to permute the observed data in all possible ways, and thereby derive exact distributions for the test statistics of interest without making any distributional or large-sample assumptions. In contrast, standard parametric methods of inference make distributional assumptions about the data, while standard nonparametric methods of inference rely on asymptotic theory to derive approximate distributions for the test statistics. Exact nonparametric methods are particularly important for small, sparse or unbalanced data where the usual asymptotic theory breaks down. This course will cover exact inference for one, two and K-sample problems, ordered and unordered RxC contingency tables, 2x2 and 2xC contingency tables with or without stratification, and logistic regression. A unified view, encompassing both continuous and categorical data, will be presented based on the permutation principle. Modern algorithmic advances that make exact permutational inference computationally feasible will be treated in depth. The methods will be illustrated by several biomedical data sets. This course will use StatXact and LogXact statistical packages.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO270 Statistical Science Outreach
WinterSession
Instructor TBA

2.5 credits
Course not offered 2008-2009; offered alternate years.
Seminars. Sixteen 2-hour sessions during WinterSession.

This is a seminar aimed at broadening the background of students in probability and statistics. Students will be expected to give short presentations from expository articles and papers. Articles will be chosen on the basis of ideas rather than technical content. There will be some emphasis on historical developments. This course is suitable for students in any year of the Biostatistics program.
Course Note: Enrollment in a biostatistics degree program required; this class cannot be used to satisfy the intermediate requirement for doctoral students in the Department of Biostatistics; Pass/Fail grading option only, minimum enrollment of 10 students required; signature of instructor required; Course meets 10:30 am to 12:30 pm. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO276 Sequential Analysis
Fall
Dr. C. Mehta

2.5 credits
Course not offered 2009-2010 and 2010-2011; offered alternate years
Lectures. One 2-hour session each week.

This course will cover the basic theory underlying the design and interim monitoring of group sequential clinical trials and will illustrate the theory with examples of real clinical trials. Topics include: distribution theory for stochastic processes with independent increments; the recursive integration algorithm; stopping boundaries and error spending functions; maximum information trials; conditional power and stochastic curtailment; repeated confidence intervals; inference following group sequential testing; sample size re-estimation; more general adaptive
designs. Software support for this course will be provided by East software.

Course Note: BIO230 or signature of instructor required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO277 Computational Biology
Fall
Dr. G. Yuan

5.0 credits
Lectures. Two 2-hour sessions each week.

Instroduction to statistical methods for biological problems including microarray analysis, motif finding, CHIP-chip data, and gene regulatory network. Topics include multiple hypothesis testing, clustering and classification, variable selection, hidden Markov model, and Bayesian network.

Course Note: BIO 230 and BIO231, or permission of instructor required; ordinal grading option only. Cross-listed; HSPH students must register for HSPH course.

Course Evaluations


BIO283 Spatial Statistics for Health Research and Social Inquiry
Spring
Dr. C. Paciorek, Dr. L. Ryan, Dr. R. Izem

5 credits
Course Not Offered 2008-2009
Lectures, laboratories. Two 1.5-hour sessions each week. One 2-hour lab each week.

Introduction to spatial statistics with application to public health and social science research. Emphasizes methods for the analysis and visualization of three basic types of spatial data: areal data, point (geostatistical) data, and point processes. Heavy emphasis on real applied problems through case studies, guest lectures, and student projects. Basic GIS skills will be covered in a short module. Note that prerequisites are guidelines and students are encouraged to consult the instructors.
Course Note: BIO 210, or 211, or 213 and BIO 503, or permission of instructor.

Course Evaluations


BIO287 Public Health Surveillance
Spring
Dr. A. Ozonoff, Dr. M. Pagano

2.5 credits
To be given 2008-2009; offered alternate years.
Lectures. One 2-hour session each week.

Surveillance is an important component of public health. Its function is to detect and monitor disease incidence and it has three components: to collect data, to analyze it, and to report the results. This course considers all three aspects with particular emphasis on the analysis of surveillance data. We shall consider both the more traditional surveillance systems, where data collection and reporting are done at a relatively leisurely pace, and systems that provide for immediate feedback and thus are designed to detect biological terrorism and other situations where rapid response is desirable. We shall study both passive and active surveillance systems. Statistical techniques covered include time series, clustering methods, and other geo-temporal techniques.
Course Note: BIO 232, or signature of instructor required; no auditors.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO288 Semiparametric Methods for Analysis of Missing and Censored Data
Spring
Dr. A. Rotnitzky

2.5 credits
Course not offered 2006-2007; offered alternate years.
Lectures. One 2-hour session each week.

The goal of the course is to provide a comprehensive discussion of optimal estimation techniques for low dimensional parameters of semiparametric models (i.e. models with infinite dimensional nuisance parameters) for complex longitudinal data subject to informative censoring or missingness. The course will start with the discussion of the fundamental notions and results of semiparametric theory: pathwise derivatives, tangent space, semiparametric variance and information bounds, and influence functions. It will then provide a general estimating function methodology for locally semiparametric efficient estimation and doubly robust estimation under data that are coarsened at random. This general methodology will then be applied to derive locally efficient doubly robust estimators of 1) regression parameters in multivariate generalized linear models subject to missing at random data, 2) the survival function of an endpoint subject to dependent right censoring, 3) the quality of life adjusted survival time subject to dependent right censoring 4) the survival function of multivariate failure time data subject to univariate (dependent) censoring, 5) Cox regression parameters based on dependent right censored data and 6) smooth parameters of the distribution of a time to an endpoint outcome based on current status data and interval censored data.
Course note: BIO231, BIO244, and BIO250 or signature of instructor required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO289 Reading the Medical Literature: A Course for Statisticians
WinterSession
Dr. D. Neuberg

1.25 Credits
Course not offered 2008-2009
Seminars. Eight 2-hour sessions.

The goal of this course is to offer students the opportunity to improve their skills at critical reading of the medical literature. Papers will be approached from a statistical point of view, and discussion will focus how to identify the structure of the clinical study, including the statistical design, from the ultimate published report of results. Papers will be drawn from the recent medical literature, with an emphasis on publications appearing in the New England Journal of Medicine, Lancet, and other journals of similar nature. For each paper, one student will summarize the content of the paper, and a second student will critique the paper. All students are expected to read every paper, and be prepared to participate in classroom discussion.
Course note: Registration will be limited to students enrolled in a degree program in Statistics or Biostatistics; pass/fail grading option only. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO291 Statistical Methods for Causality
Spring
Dr. Rotnitzky, Dr. Tchetgen, Dr. Li, Dr. Robins

5 credits
Lectures, laboratories. Two 2-hour sessions each week. One 2-hour lab each week.

Theory of directed acyclic graph models. Identifiability of causal contrasts. Theory and applications of locally semiparametric efficient doubly-robust estimation in two models for counterfactual variables: marginal structural models and structural nested models.

Course Note: BIO 231, or permission of instructor required. Lab or section times to be announced at first meeting. Minimum enrollment required.
Course Evaluations


BIO292 Introductory Genomics & Bioinformatics for Health Research
Spring 1
Dr. J. Quackenbush

2.5 Credits
Lectures. Two 2-hour sessions each week.

This survey course is intended for a wide audience and will provide an introduction to genomics-inspired techniques and bioinformatics tools, including genome sequencing, DNA microarrays, proteomics, and publicly available databases and software tools.

Course Note : BIO200, or BIO201, or BIO202 and BIO203, or BIO206 and one of BIO207, BIO208, or BIO209, and EPI200 or EPI201, or signature of instructor required; lab or section times to be announced at first meeting.

Course Evaluations


BIO300 Independent Study
Fall 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)

Course Evaluations


BIO300 Independent Study
Fall
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. Theses programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study/ tutorial contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail grading option only; signature of instructor required. (5.06)

Course Evaluations


BIO300 Independent Study/ Tutorial
Fall 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. Theses programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study/ tutorial contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail grading option only; signature of instructor required. (5.06)


Course Evaluations


BIO300 Independent Study/ Tutorial
Spring 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. Theses programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study/ tutorial contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail grading option only; signature of instructor required. (5.06)


Course Evaluations


BIO300 Independent Study/ Tutorial
Spring
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. Theses programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study/ tutorial contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail grading option only; signature of instructor required. (5.06)


Course Evaluations


BIO300 Independent Study/ Tutorial
Spring 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. Theses programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study/ tutorial contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail grading option only; signature of instructor required. (5.06)


Course Evaluations


BIO300 Independent Study/ Tutorial
WinterSession
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. Theses programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study/ tutorial contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail grading option only; signature of instructor required. (5.06)


Course Evaluations


BIO300 Independent Study/ Tutorial
Summer
Department Members

Time and credit to be arranged.

Guided study in specific areas of statistical methodology and applications.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required; students may register for a maximum of 5 credits in the summer term.
Course Evaluations


BIO300 Independent Study/ Tutorial
Summer 2
Department Members

Time and credit to be arranged.

Guided study in specific areas of statistical methodology and applications.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required; students may register for a maximum of 5 credits in the summer term.
Course Evaluations


BIO311 Teaching
Fall 1
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department in laboratory instruction and the development of teaching materials.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)
Course Evaluations


BIO311 Teaching
Fall
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department in laboratory instruction and the development of teaching materials.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)
Course Evaluations


BIO311 Teaching
Fall 2
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department in laboratory instruction and the development of teaching materials.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)
Course Evaluations


BIO311 Teaching
Spring 1
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department in laboratory instruction and the development of teaching materials.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)
Course Evaluations


BIO311 Teaching
Spring
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department in laboratory instruction and the development of teaching materials.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)
Course Evaluations


BIO311 Teaching
Spring 2
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department in laboratory instruction and the development of teaching materials.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)
Course Evaluations


BIO311 Teaching
Summer 1
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department in laboratory instruction and the development of teaching materials.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required; students may register for a maximum of 5 credits in the summer term.
Course Evaluations


BIO311 Teaching
Summer
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department in laboratory instruction and the development of teaching materials.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required; students may register for a maximum of 5 credits in the summer term.
Course Evaluations


BIO311 Teaching
Summer 2
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department in laboratory instruction and the development of teaching materials.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required; students may register for a maximum of 5 credits in the summer term.
Course Evaluations


BIO312 Consultation
Fall
Dr. D. Wypij

Time and credit to be arranged.

Work with members of the department on current statistical consultation activities.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO312 Consultation
Spring
Dr. R. Betensky

Time and credit to be arranged.

Work with members of the department on current statistical consultation activities.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO312 Consultation
Summer 1
Department Members

Time and credit to be arranged.

Work with members of the department on current statistical consultation activities.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required; students may register for a maximum of 5 credits in the summer term. Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO312 Consultation
Summer
Department Members

Time and credit to be arranged.

Work with members of the department on current statistical consultation activities.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required; students may register for a maximum of 5 credits in the summer term. Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO312 Consultation
Summer 2
Department Members

Time and credit to be arranged.

Work with members of the department on current statistical consultation activities.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required; students may register for a maximum of 5 credits in the summer term. Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO313 Computing
Fall
Dr. C. Li, Dr. D. Wypij

Time and credit to be arranged.

Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO313 Computing
Spring
Dr. D. Wypij

Time and credit to be arranged.

Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO313 Computing
Summer
Department Members

Time and credit to be arranged.

Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required; students may register for a maximum of 5 credits in the summer term. Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO350 Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO350 Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO350 Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO350 Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO350 Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO350 Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO350 Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO350 Research
Summer 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO350 Research
Summer
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO350 Research
Summer 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their written qualifying exam and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


BIO400 Non-Resident Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO400 Non-Resident Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO400 Non-Resident Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO400 Non-Resident Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO400 Non-Resident Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO400 Non-Resident Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO400 Non-Resident Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO400 Non-Resident Research
Summer 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO400 Non-Resident Research
Summer
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO400 Non-Resident Research
Summer 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their Written Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


BIO501 Linear and Longitudinal Regression
Summer 2
Dr. G. Fitzmaurice

2.5 credits
Lectures, laboratories. 5 1.75-hour sessions each week.

This course is intended for students who are already very comfortable with fundamental techniques in statistics. The course will cover methods for building and interpreting linear regression models, including statistical assumptions and diagnostics, estimation and testing, and model building techniques. These models will be extended to handle data arising from longitudinal studies employing repeated measurement of subjects over time. Lectures will be accompanied by computing exercises using the SAS statistical package.

Course Note: BIO200, or BIO201, or BIO206, or BIO202 and BIO203 is required. Ordinal grading option only. Lab or section will be announced at first meeting

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


BIO503 Introduction to Programming and Statistical Modeling in R
WinterSession
J. Marr, Dr. C. Paciorek (S)

1.25 credits
Seminars. Five 3-hour sessions during WinterSession

This course is an introduction to R, a powerful and flexible statistical language and environment that also provides more flexible graphics capabilities than other popular statistical packages. The course will introduce students to the basics of using R for statistical programming, computation, graphics, and modeling. We will start with a basic introduction to the R language, reading and writing data, and graphics. We then discuss writing functions in R and tips on programming in R. Finally, the latter part of the course will focus on using R to fit some important types of statistical models, including linear regression, generalized linear models, generalized additive models, and mixed effects models.

Our goal is to get students up and running with R such that they can use R in their research and are in a good position to expand their knowledge of R on their own. Basic knowledge of statistics at the level of a basic understanding of linear regression is required.
Course note: Pass/Fail or audit grading option only.
Course Evaluations


BIO504 Introduction to Geographical Information Systems Using ArcGIS
WinterSession
Dr. S. Srinivasan, Dr. C. Paciorek (S)

1.25 credits
Lectures. Five 3.5 hour sessions each week.

This course introduces Geographic Information Systems (GIS) and their applications. GIS is a combination of software and hardware with capabilities for manipulating, analyzing and displaying spatially referenced information. Emphasis on learning practical skills using ArcGIS software. Five combined lecture/lab sessions. (10.06)

Course Evaluations


BIO505 Database Design and Usage for Health Research
WinterSession
Dr. J. White, Dr. J. Quackenbush

1.25 credits
Lectures. Eight 2-hour sessions.

Essential concepts needed to design, implement, and use a database using Oracle Express. Principles of relational database structures and objects, Structured Query Language (SQL), security concepts, schema design, referential integrity, and basic database administration. Students will learn to produce reports and datasets that can be imported into a statistical analysis package. Special emphasis on studies that incorporate high dimensional genetics and genomic data.

Course Note: Ordinal grading option only.

Course Evaluations


BIO506 Introduction to Computational Biology
WinterSession
Dr. W. Hide, Dr. J. Quackenbush, Dr. D. Osterbur

2.5 Credits
Lectures. Five 8-hours sessions in winter session.

This is an introductory course intended for broad audience seeking an intensive introduction into the application of computational biology in genomics. The aim is to provide students with ability to navigate datasets and public resources so that they can manipulate their high dimensional data and perform appropriate analyses to solve computational biology problems. Students will be introduced to biology principles and genome technologies. They will gain understanding of tools available both on the web and also through the UNIX command line. They will be introduced to scripting and data set manipulation. Students will gain an understanding of the vocabulary of computation biology, its computational tools, data management, and analysis of large-scale biological datasets builds around real world problems undertaken in a project format. Techniques interpreting genomic data will be presented in a mixed lecture and practical workshop format.

Course Note: Ordinal Grading Option Only.
Course Evaluations


DBS205 Biological Sciences Seminars
Fall
Cross-listed at FAS as BPH-219

Dr. M. Wessling-Resnick
5 credits
Seminars. Two 1.5-hour sessions each week.

Faculty present seminars on their current research in the biological sciences and direct a student discussion of the logic and experimental design of this research. Topics include chemical and viral carcinogenesis, DNA damage and repair, immunology, molecular biology, metabolism, cardiovascular disease, parasitology, and how these areas apply to public health issues.

Course Note: Required for first-year students in the DBS/BPH program; ordinal grading option only. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


DBS300 Laboratory Rotations
Fall
Department Members

Time and credit to be arranged.
Laboratories. 12-20 hours each week.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. Offers hands-on experimental methods of research in the biological sciences. Students perform individualized and original laboratory work. Includes participation in seminars, journal clubs, and assigned readings.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)
Course Evaluations


DBS300 Laboratory Rotations
Spring
Department Members

Time and credit to be arranged.
Laboratories. 12-20 hours each week.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. Offers hands-on experimental methods of research in the biological sciences. Students perform individualized and original laboratory work. Includes participation in seminars, journal clubs, and assigned readings.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)
Course Evaluations


DBS301 Special Seminar
Fall
Department Members

Time and credit to be arranged.

Topics and meeting time to be determined.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)

Course Evaluations


DBS301 Special Seminar
Spring
Department Members

Time and credit to be arranged.

Topics and meeting time to be determined.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)

Course Evaluations


DBS350 Research
Fall
Department Members

Time and credit to be arranged.

For doctoral students who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department. Inquiries about specific research opportunities should be addressed to the chair of the department.
Course Note: Pass/ fail only; signature of instructor required. (5.06)

Course Evaluations


DBS350 Research
Spring
Department Members

Time and credit to be arranged.

For doctoral students who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department. Inquiries about specific research opportunities should be addressed to the chair of the department.
Course Note: Pass/ fail only; signature of instructor required. (5.06)

Course Evaluations


EH201 Introduction to Environmental Health
Fall 2
Dr. R. Goldman

2.5 credits
Interactive lectures in-class, case discussions and option for on-line discussions. Five 2-hour sessions each week.

This course offers a general introduction to environmental health from local to global, addressing fundamental topics and current controversies. The first part of the course covers core topics that prepare students to more fully understand and address environmental health issues: toxicology, exposure assessment, environmental epidemiology, risk assessment/risk management, air pollution, water pollution, and environmental justice. Using the tools from the first part of the course, students then participate in sessions on occupational health, children's health and the environment, injuries, climate change and health, the built environment/urban sprawl, and debates concerning pesticide use.Students can actively engage with the course material through in-class and online, case discussions, debates, and review of environment-related current events. This course provides an excellent introductory foundation in environmental health for all professional master's degree candidates, whether or not specializing in environmental health. The course fulfills the environmental health requirement for all professional master's degree programs.
Activities: Two brief graded written assignments (assigned written case analysis and pesticide debate position); final individual case project, in-class, on-line discussions and exercises.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.

Course Evaluations


EH201 Introduction to Environmental Health
Summer 2
Dr. R. Goldman, Dr. M. Kile

2.5 credits
Interactive lectures in-class, case discussions and option for on-line discussions. Five 2-hour sessions each week.

This course offers a general introduction to environmental health from local to global, addressing fundamental topics and current controversies. The first part of the course covers core topics that prepare students to more fully understand and address environmental health issues: toxicology, exposure assessment, environmental epidemiology, risk assessment/risk management, air pollution, water pollution, and environmental justice. Using the tools from the first part of the course, students then participate in sessions on occupational health, children's health and the environment, injuries, climate change and health, the built environment/urban sprawl, and debates concerning pesticide use.Students can actively engage with the course material through in-class and online, case discussions, debates, and review of environment-related current events. This course provides an excellent introductory foundation in environmental health for all professional master's degree candidates, whether or not specializing in environmental health. The course fulfills the environmental health requirement for all professional master's degree programs.
Activities: Two brief graded written assignments (assigned written case analysis and pesticide debate position); final individual case project, in-class, on-line discussions and exercises.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.

Course Evaluations


EH202 Principles of Environmental Health
Spring 1
Dr. D. Dockery, Dr. M. Kile

2.5 credits
Lectures, case studies. Two 2-hour sessions each week.

This course is appropriate for students interested in learning quantitative methods for assessing environmental exposures and hazards. This course is directed at first year Environmental Health students and MPH students with specific interest or experience in environmental health or for those students who have taken EH 201. Students who have taken EH 201 can take EH 202 as a sequel for more intensive training in environmental health. Students will learn methods for quantitative evaluation and public health responses to environmental hazards through lectures, problem solving, and case studies. The course is structured around specific tools including exposure assessment, epidemiology, toxicology and pathophysiology, risk assessment, life cycle analysis, and environmental policy.

Course Evaluations


EH205 Human Physiology
Fall
Cross-listed at FAS as BPH-208 and at HMS as BPH-728.0

Dr. S. Shore, Dr. N. Long Sieber
5 credits
Lectures, laboratory. Two 2-hour sessions each week, including 1 laboratory meeting during the semester.

As an introduction to the principles governing function in the human body, this course is designed to provide a framework in physiology for future public health researchers and professionals who have not taken college level physiology courses. Emphasis is placed on the concept of homeostasis and on integrative aspects of physiology. Examples of pathophysiology and environmental physiology will highlight these processes.
Course Activities: Problem sets, exams, laboratory.
Course Note: College-level introductory biology or permission of instructor required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH208 Pathophysiology of Human Disease
Spring
Cross-listed at FAS as BPH-210 and at HMS as BPH-729.0

Division of Biological Sciences and Department of Environmental Health
Dr. L. Kobzik
5 credits
Lectures, seminars. Two 2-hour sessions each week.

Surveys major human disease problems in the cardiovascular, respiratory, hematopoietic, reproductive and gastrointestinal systems. Emphasis on understanding the pathophysiologic basis of common disease manifestations and the pathogenesis of the disease process. Relevant public health perspectives on the epidemiology or control of diseases are also integrated.
Course Note: College level physiology, EH 205, or equivalent required; cross-listed course, HSPH students must register for HSPH course. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH223 Advanced Respiratory Physiology
Fall
Cross-listed at FAS as BPH-206

Dr. J. Butler
5 credits
Lectures, demonstrations. Two 1.5-hour sessions each week.

This course will cover in depth three major aspects of pulmonary physiology. At the level of structure, lung mechanics in health and disease will be described, along with pulmonary function tests and their interpretation. At the level of function, gas exchange with blood will be emphasized, with quantitative emphases on the distributions of
ventilation and perfusion. The control of breathing will be explored, with an emphasis on dyspnea and the role of chemical drive and its modulation. Special topics may include, amoung other themes, aerosol transport and deposition, host defense and the inflammatory response, and airway hyperactivity in asthma.

Text:

1. J.B. West, Respiratory Physiology, 5th edition, Williams and Wilkens, Baltimore, 2004
2. J.B. West, Pulmonary Pathophysiology, 5th edition, Williams and Wilkens, Baltimore, 2003.

Optional resource text: E.R. Weibel, The Pathway for Oxygen, Harvard Univ. Press, 1984

There will be one midterm exam, a research paper with class presentation, and a final. Homework consists in studying text material and lecture notes, and classroom participation in discussion of provocative and nontrivial questions raised during the previous class.

Course Note: EH 205 or equivalent or college-level physiology strongly suggested.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH225 Advanced Topics in Physiology
Spring
Cross-listed at FAS as BPH-207 and at HMS as BPH-727.0

Dr. J. Fredberg
5 credits
Lectures, supervised independent study. Two 1.5-hour sessions each week.

This course provides opportunities for students interested in the respiratory system to focus on special topics in lung biology. This year's emphasis will be on the fundamental physical basis and quantitative description of chemical, electrical and mechanical signaling within the cell. Specific topics covered will include passive diffusion, facilitated diffusion, solvent and solvent transport, channels, action potentials, membrane transport, receptor-ligand binding.
Course Activities: Students will explore one particular aspect and write a major research paper. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH231 Occupational Health Policy and Administration
Spring
Dr. C. Langer (P), Dr. D. Christiani (S)

2.5 credits
Lectures, seminars, case studies. One 2-hour session each week.

Examines the legal, regulatory and economic foundations of occupational health activities in the United States. Discusses the roles of government, unions, corporations, and research organizations. Helps students acquire an understanding of management functions in corporations.
Course Activities: Students develop the necessary knowledge and skills in the above areas to apply medico-legal and risk management principles to achieve a healthful workplace. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH232 Introduction to Occupational and Environmental Medicine
Spring
Dr. S. Kales, Dr. D. Christiani

2.5 credits
Lectures. One 2-hour session each week.

Overview of Occupational and Environmental Medicine including: the diagnosis and management of illnesses following exposure to specific workplace substances, environmental and community hazards, such as asbestos, lead, organic solvents, and vibration; methods of diagnosis of early organ system effects of chemicals and techniques for assessing impairment and disability; as well as, medicolegal aspects of occupational health.
Course Activities: Mid-term exam and Final exam.
Course Prerequisites: This is a clinical and preventive medicine course. The material is taught at a post-graduate level, and a medical or allied health background is required. The majority of students will be physicians, nurses, dentists, pharmacists and students in those fields. Persons without prior biomedical training may NOT take the class for an ordinal grade. Such students are welcome to audit the class. In certain exceptions, if discussed with the instructors, such students may be granted permission by the instructors to take the course on a pass/fail basis.
Course Note: Basic course in toxicology recommended; instructor's signature required if student has not completed prerequisite. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH236 Epidemiology of Environmental & Occupational Health Regulations
Fall
Dr. G. Wagner, Dr. D. Wegman, Dr. J. Cavallari ,Dr. K. Miller Applebaum

5 credits
Seminars, case studies. One 3-hour session each week.

Provides students with the opportunity to review the scientific basis for the association of selected occupational and environmental exposures and disease. Special emphasis is placed on the evaluation of the epidemiologic literature, cancer, and respiratory disease. Attention is directed to the interface of science and regulatory policy and the role of risk analysis in setting health standards.
Course Activities: Discussions based on the process leading to setting of standards.
Course Notes: Prerequisites: BIO200, BIO201 or BIO202, and EPI200 or EPI201, and EH201 or EH202 required. Ordinal grading option only. Formerly EH235.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH241 Occupational Safety and Injury Prevention
Spring
Dr. J. Dennerlein, Mr. R. Youngstrom, Mr. R. Spielvogel

2.5 credits
Lectures, seminars. One 2-hour session each week.

This course in occupational safety works towards the prevention of work-related injury and illnesses through proactive management and control of workplace hazards. The primary objectives of the course are to: (1) identify fundamental workplace hazards, (2) develop a basis of basic government and voluntary regulations, (3) understand issues pertaining to specific and different industries, and (4) understand various safety management programs.

Course Activities: Lectures and group discussions, and a term project.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH243 Ergonomics/Human Factors
Fall
Dr. J. Dennerlein, Mr. T. Courtney, Dr. V. Ciriello

2.5 credits
Lectures, seminars. One 2-hour session each week.

Occupational ergonomics applies the fundamental science and theories of epidemiology, physiology, biomechanics, and psychology, to name a few, to the design and implementation of physical environments with the goal of optimizing system performance and human well-being. Within the public health framework, ergonomics focuses on the prevention of work-related musculoskeletal disorders, injury and disability, especially those associates with lifting and repetitive tasks. Prevention efforts will focus on redesigning of sick jobs and a systematic and process approach to physical ergonomics programs.

Course Activities: Lectures and group discussions, and a term project analyzing a real world job.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH250 Protecting Workers & Communities from Hazardous Substances
Spring
Dr. S. Rudnick, Mr. K. Martin, Mr. R. Spielvogel

2.5 credits
Not offered 2005-2006. Course offered alternate years.
Lectures, laboratory sessions, field trip. One 2-hour session each week.

This course covers the recognition, evaluation, and control of worker and community exposure to hazardous substances. Particular emphasis is placed on remediation of hazardous waste sites, emergency response activities and related operations.
Course Activities: Written reports, class discussions and "hands-on" activities. Forty-hour Hazardous Waste Operations and Emergency Response certification may be awarded depending upon student's curriculum.
Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH253 Ventilation
Spring
Dr. S. Rudnick, Mr. L. DiBerardinis

2.5 credits
Course offered 2006-2007; offered alternate years.
Lectures, laboratory sessions, field trip. One 2-hour session each week.

This course covers the ventilation systems used to protect industrial workers and to provide healthy indoor air quality in buildings.
Course Activities: Class discussion, problem-solving assignments, "hands-on" activities.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH254 Evaluation and Control of Noise and Vibration
Spring
Dr. S. Rudnick

2.5 credits
Course offered 2007-2008; Offered alternate years.
Lectures, laboratory sessions, field trips. One 2-hour session each week.

This course covers the fundamental principles, evaluation, and control of noise and vibration with an emphasis on protecting workers and, to a lesser extent, the surrounding community.
Course Activities: Lectures, class discussion, problem solving assignments, lab, and class project.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH256 Introduction to Aerobiology
Fall
Dr. J. McDevitt, Dr. D. Milton, Mr. M. Muilenberg, Dr. C. Rogers

2.5 credits
Lectures, seminars. One 2-hour session each week.

This course emphasizes the pathways from reservoirs for biological-source disease agents to the ultimate response. Characteristics of the organism and their associated disease agents, biological and physical factors affecting aerosol formation, dispersion and decay, exposure factors, dose response data, and mechanisms of the disease processes are included, as are approaches for investigation, research design and risk assessment.
Course Activities: Lectures, discussions, quizzes and a research paper. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH257 Water Pollution
Spring
Dr. J. Shine

5 credits
Lectures. Two 2-hour sessions each week.

This course is designed to teach an understanding of the basic principles of water pollution and water pollution issues on local, regional and global scales. The course will begin with a discussion of the basic chemical, physical and biological properties of water and water contaminants. Subsequent lectures will cover specific chemical and biological contaminants in ground, surface, and marine waters; sources, fate, transport, and transformation of contaminants; monitoring techniques, water source protection and resource management; water and wastewater treatment; transmission of waterborne disease; toxicological concerns of chemicals in water, including disinfection byproducts; and interactions with the air and land environments. Invited lecturers will cover issues such as harmful algal blooms, groundwater modeling, coastal zone management, and regulatory approaches for aquatic ecosystem protection.
Course Activities: Class discussions, homework assignments, exams and final project. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH262 Introduction to the Work Environment
Fall
Dr. R. Herrick, Dr. J. Stewart

2.5 credits
Lectures, case studies. One 2-hour session each week.

The course comprises introductory lectures and discussions on key aspects of industrial hygiene and occupational health covering recognition, evaluation and control of health hazards at work. Consideration is given to chemical, physical and biological hazards, and the criteria for the evaluation of each.
Course Activities: Written projects, class discussions, demonstrations.
Course Note: While intended primarily for students planning a career in occupational health, this course provides background to the subject for students studying environmental issues and is strongly recommended for students intending to take ID263. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH263 Analytical Methods and Exposure Assessment
Spring
Dr. H. Suh

5 credits
Course not offered 2006-2007; offered alternate years.
Lectures, field work. Two 2-hour sessions each week.

This course will examine methodological issues associated with the design and execution of studies designed to measure environmental exposure to chemical and biological contaminants. The first half of the course will be lecture based, and will address topics such as: study design issues, implementation of quality control/ quality assurance programs, data analysis, protocols for sampling air, water, sediments, and soil for contaminants of concern, and analytical techniques used to measure chemical and biological constituents in the laboratory. During the second half of the semester, groups of students will design and execute their own field investigation using these techniques. The design and results of these projects are presented in class.
Course Activities: Lectures, written reports, problem sets, exams, class presentations, field work and final paper.
Course Note: Signature of instructor required for students not in the Exposure, Epidemiology and Risk Program. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH264 Water Systems Management
Fall
TBA

2.5 credits
Not Offered 2007-2008
Lectures, seminars, case studies. One 2-hour session each week.

Provides students with an understanding of water engineering principles, emphasizing design and treatment of water supply systems in developing and developed countries.
Course Activities: Oral and written projects, class discussions, two field trips.
Course Note: Ordinal grading option only. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH267 Indust Hygiene/Ergo Internship & Environmental Sciences Rsch Sem
Spring
Dr. R. Herrick, Dr. J. Dennerlein, Dr. P. Koutrakis

2.5 credits
Seminars, case studies. One 2-hour session each week.

Material for this course is required for Industrial Hygiene and Ergonomics concentrators doing the Internship Program and for Exposure, Epidemiology and Risk Program students doing research. The objective of the course is to refine communication skills. Students are required to prepare their own report, peer-review others and present the results.
Course Activities: Students present seminars on their recent internship or research projects.
Course Note: Instructor's signature required; ordinal credit only. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH269 Exposure Assessment for Environmental&Occupational Epidemiology
Spring
Dr. T. Smith, Dr. D. Dockery

2.5 credits
Lectures, readings, case studies. One 2-hour session each week.

Reviews the methods used to characterize environmental and occupational exposures. Presents approaches for biologically based exposure assessment matched to epidemiologic designs. Emphasizes evaluation of scientific literature.
Course Activities: Students will critique 4 case study papers. Instructors will provide feedback.
Course Note: Course recommended for doctoral and post-doctoral students in epidemiology, environmental science and engineering, and environmental biostatistics. Strongly recommend EH215 be taken concurrently or previously. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH270 Environmental Risk Management
WinterSession
Dr. R. Pojasek, Dr. J. Spengler

5 credits
Lectures, seminars, case studies. One day lecture; half day seminar and work on the case study (six hours during each week.)

Students will learn the skill of using problem solving tools for dealing with environment, health and safety problems and managing the associated environmental risks. A number of tools are presented within a systems approach. These tools are widely used by industries and governmental organizations throughout the world. The student should be prepared to use these skills in team environments once they graduate from Harvard. Means of measuring progress and managing programs using the systems approach will be presented and discussed.
Course Activities: A term paper will be completed by small groups on an actual project on a Harvard campus or local institution. This will reinforce the skills gained in class. Course will meet Tuesdays, January 3, 10, 17, 24 from 9 am to 4 pm and Fridays, January 6, 13, 20 from 9 am to 3 pm.
Course Note: Ordinal grading only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH273 Industrial Hygiene/Ergonomics Internship
Fall
Dr. R. Herrick, Dr. J. Dennerlein

20 credits
Field work. Normal working hours of the host organization, in addition to time required for relevant reading.

The student works in an industrial or similar workplace under the direction of a qualified and experienced industrial hygienist or ergonomist (a mentor.) Generally the first half of the six-month period is devoted to learning evaluation techniques (e.g. personal air sampling, direct reading instrumentation, ventilation measurements,) and the second half to studying some specific hazard or problem in depth, and preparing material for presentation in the succeeding course, EH267.

Course Note: Completion of the first year of the two-year masters degree program in Industrial Hygiene required, ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH277 Genetic Epidemiology and Gene Mapping
Spring 1
Dr. Xin Xu, Dr. T. Niu

2.5 credits
Course offered 2006-2007; offered alternate years.
Lectures, seminars. One 2-hour session each week.

This multidisciplinary course is designed to provide a state-of-the-art guide to the emerging fields of modern genetic epidemiology and gene mapping in complex disorders. The completion of the Human Genome Project by 2003 will bring paradigmatic shifts of future human genetic epidemiologic studies. This course provides a comprehensive overview of the background of epidemiologic studies, epidemiologic methods and study designs, family and sib pair ascertainment, gene mapping technologies, computer software, data analysis, and interpretation. It will also explore a number of innovative new approaches for mapping genes of complex human diseases. In addition, the course will address the issues of genetic susceptibility, gene-gene interactions, and gene-environment interactions underlying common human diseases.
Course Activities: Preparatory readings required for each lecture. Grades will be based on homework assignments, a quiz, and class participation.
Course Note: EPI 201 and BIO 211, BIO 200, BIO 201 or BIO 202 and BIO 203 required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH278 Human Health and Global Environmental Change
Spring 2
Dr. A. Bernstein, Dr. M. Kile

2.5 credits
Lectures. Two 2-hour sessions each week.

Human activity has changed the atmosphere and altered terrestrial and marine ecosystems on a global scale for the first time in history. Evidence is mounting that these changes may already be having serious effects on human health, and there is growing concern that in coming decades the effects could be catastrophic. This course will examine in detail climate change and biodiversity loss as two primary examples of global environmental change and their human health dimensions. The challenges of addressing global environmental problems from a public policy and communications standpoint will also be explored. A multi-disciplinary faculty will provide an integrated assessment of these issues. The course will be open to all students at Harvard University, but preference will be given to students from HSPH, HMS, and KSG, as well as to Environmental Science Public Policy majors in the Faculty of Arts and Sciences.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH279 Radiation Environment:Its Identification, Evaluation & Control
Fall
Dr. E. Maher

2.5 credits
Lectures, case studies. One 2-hour session each week

Starting with the fundamentals of radiation protection, this course then treats in-depth selected topics in occupational and environmental radiation protection (e.g. risk assessment of exposures to diagnostic and therapeutic x rays; use of lung and metabolic models in evaluation of the hazard from inhalation and ingestion of radioactive chemicals; hazard from indoor radon; radiological assessments regarding nuclear power, war, and radiological terrorism; hazards from microwaves, cellular phones and other sources of nonionizing radiation; case studies of radiation accidents; management of university and hospital radiation programs). The course has been developed with the needs of students enrolled in environmental science and engineering, occupational health and the MPH program in mind.
Course Activities: Class discussions, homework assignments. Students will prepare a term position paper and oral presentation defending their stand on a controversial subject of their choice in a form suitable for consideration by management.
Course Note: Minimum enrollment of 10 students required; enrollment limited to 15 students; signature of instructor required. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH280 Field Methods in Environmental Health
WinterSession
Dr. R. Herrick, Dr. J. Levy, Dr. J. Shine, Dr. J. Stewart, Dr. J. Dennerlein

2.50 credits
Course not offered 2006-2007
Lectures, case studies, labs. Twelve 3-hour sessions. Fieldwork.

Students will gain experience at making evaluations, taking measurements and collecting samples in the field, covering the range of media and settings we work in-that is, the workplace, the indoor environment, and the community environment. Students will gain familiarity with measurement and evaluation methods for a range of environmental hazards and risk factors, by using the equipment, practicing the techniques, and analyzing and interpreting their findings.

These goals will be accomplished through a set of four case studies, each of which will be coordinated by a faculty member. The case topics are: Occupational Environment (Bob Herrick), Water and Land (Jim Shine), Outdoor Air (Jon Levy), Indoor Environment (Jim Stewart) and Ergonomics (Jack Dennerlein.)

Each case consists of a two-day block, divided as follows:
Pre-class: Background readings assigned, including description of the case posted on the course i-commons site.
Day 1: Class meets in the morning, case is presented, discussion and questions, class prepares plan of field activities, then goes to a field site to conduct evaluation using tools and methods as planned in the morning session.
Day 2: Class meets in the morning, analyzes data and findings from field activities, interprets information, prepares summary.

The expectation is that each case will include about six hours of classroom time and twelve hours of outside time, including the field site visit. The structure of each case may vary slightly depending on the nature of the case.
Course note: No auditors. (12.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH282 Injury Epidemiology and Prevention
Spring 2
D. Lombardi, M. Perry

2.5 credits
Course offered alternate years; next offering spring 2009.
Seminar. One 3-hour session each week.

This course will focus on the use of epidemiological methods to study injuries and their prevention. Topics covered include designing surveillance systems and analytic studies, measuring exposures and outcomes, and implementing prevention programs. Injury categories will focus on occupational and nonoccupational contexts, and intentional and non-intentional sources of injuries.
Course notes: EPI 200 or EPI 201 required; no auditors



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH285 Industrial Ecology and Life Cycle Assessment
Fall
Department of Environmental Health and the Department of Health Policy and Management

Dr. G. Norris, Dr. J. Spengler
5.0 credits
Course offered 2008-2009. Offered alternate years.
Lectures, seminars, case studies. One 3-hour session each week. Additional special web Base software sessions.

Policy-makers, communities, civil society, academics and business leaders around the world are increasingly concerned about the environmental and social impacts of production and consumption.
Part of the response is the increasing use by industry and governments of Life Cycle Analysis (LCA), a growing and diversifying set of methods for systems analysis of environmental, economic, and social impacts of products systems. This course will enable participants to develop a hands-on, in-depth understanding of the frameworks, principles, tools, and applications of life cycle assessment.

The course is designed to enable participants to become capable and self-reflective practitioners of LCA. Thus, we will delve into the methods of life cycle assessment, working practical problems of real-world significance using state-of-the-art software and data. Once we have developed a practical and in-depth understanding of these methods, we will go further, to consider the strengths, weaknesses, barriers and opportunities associated with current application of the methods in industry and policymaking. Finally, we will look at emerging US and global trends in life cycle methods and application, as this field is increasingly called upon, since the Johannesburg 2002 World Summit on Sustainable Development, to address the full spectrum of social, economic, and environmental aspects of sustainability. (8.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH290 Research in Physiology
Fall 1
Dr. J. Godleski, Dr. J. Fredberg

2.5 credits per period enrolled
Seminars, case studies. Two 2-hour sessions each week.

Focuses on the design, conduct, and analysis of research in physiology. Includes laboratory experience and the acquisition of original data and culminates in the presentation of a research project at a national meeting and in the preparation of a paper suitable for publication.
Course Note: No auditors. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH290 Research in Physiology
Fall 2
Dr. J. Godleski, Dr. J. Fredberg

2.5 credits per period enrolled
Seminars, case studies. Two 2-hour sessions each week.

Focuses on the design, conduct, and analysis of research in physiology. Includes laboratory experience and the acquisition of original data and culminates in the presentation of a research project at a national meeting and in the preparation of a paper suitable for publication.
Course Note: No auditors. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH290 Research in Physiology
Spring 1
Dr. J. Godleski, Dr. J. Fredburg

2.5 credits per period enrolled
Seminars, case studies. Two 2-hour sessions each week.

Focuses on the design, conduct, and analysis of research in physiology. Includes laboratory experience and the acquisition of original data and culminates in the presentation of a research project at a national meeting and in the preparation of a paper suitable for publication.
Course Note: No auditors. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH290 Research in Physiology
Spring 2
Dr. J. Godleski, Dr. J. Fredberg

2.5 credits per period enrolled
Seminars, case studies. Two 2-hour sessions each week.

Focuses on the design, conduct, and analysis of research in physiology. Includes laboratory experience and the acquisition of original data and culminates in the presentation of a research project at a national meeting and in the preparation of a paper suitable for publication.
Course Note: No auditors. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH292 Properties and Behavior of Airborne Particles
Spring
Dr. S. Rudnick

2.5 credits
Course offered 2007-2008; offered alternate years.
Lectures, lab. One 2-hour session each week.

This course covers the fundamental properties, assessment, and control of airborne particles.
Course Activities: Lectures, class discussions, problem-solving assignments, lab. (5.06)



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH296 Occupational Biomechanics
Spring
Dr. J. Dennerlein

5.0 Credits
Course offered 2006-2007. Offered alternate years.
Lecutures. One 3-hour session each week

This course is a presentation of the anatomical and physiological basis for understanding and predicting human motor capabilities and limitations in the occupational setting. Quantitative models are developed to explain muscle strength performance, physical fatigue, and acute and chronic musculoskeletal trauma to the low back and upper extremities. Particular emphasis will be placed on the evaluation and design of manual activities in various occupations. The course will be organized for discussion-based learning. Students are expected to attend all classes and participate in the discussions. There will be extensive work in quantitative modeling, both in class and through homework problems.
Course note: EH243, EH263 or signature of the instructor required. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH297 Atmospheric Environment Seminars
Spring
Dr. P. Koutrakis, Dr. D. Dockery, Dr. S. Hanna, Dr. H. Suh, Dr. A. Eschenroeder

5.0 credits
Lectures. Two 2-hour sessions each week.

The beginning of the course identifies the hazardous and criteria air pollutants in terms of their potentials for adverse health impacts. Regulatory efforts to protect environmental health are examined. Next, the sources and controls are described in terms of the responses of the technology world to these regulatory requirements. Atmospheric phenomena affecting human exposure are covered. In place of mid-term and final examinations, each student will prepare and present two seminars based on individual investigation and analysis of the literature. One will address a topic in air quality, and the other, will analyze a journal article along with all of its implications. Both written and oral presentations will be required.

Course Evaluations


EH298 Environmental Epigenetics
WinterSession
Dr. A. Baccarelli

Winter Session
2.5 Credits
Lectures, readings, case studies. Eight 3-hour morning sessions plus two 2.5-hour afternoon sessions.

Epigenetics is a fast growing field, with increasing applicability in environmental and epidemiology studies, focusing on the alterations in chromatin structure that can stably and heritably influence gene expression. Epigenetic changes can be as profound as those exerted by mutation, but, unlike mutations, are reversible and responsive to environmental influences. The course will focus on epigenetic mechanisms and laboratory methods for DNA methylamine, his tone modifications, small non-coding RNAs, and epigenomics. Ongoing experimental, and epidemiology studies (cohort, case-control, cross-sectional and repeated measurement studies) will be presented to introduce the students to the epigenetic effects in prenatal/early and adult life of environmental factors, including air pollution, metals, pesticides, benzene, PCBs, persistent organic pollutants, and diet. The course will enable them to understand and apply epigenetic methods in multiple areas, including cardiovascular and respiratory disease, aging, reproductive health, inflammation/immunity, and cancer.

Course Evaluations


EH300 Independent Study/ Tutorial
Fall 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. Opportunities are provided for independent studies in the fields of aerosol technology, air pollution control, environmental health management, environmental epidemiology, environmental microbiology, industrial hygiene and ventilation, nuclear medicine, occupational medicine, radiological health, respiratory biology, respiratory epidemiology, injury epidemiology, ergonomics, and solid waste management.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)

Course Evaluations


EH300 Independent Study/ Tutorial
Fall
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. Opportunities are provided for independent studies in the fields of aerosol technology, air pollution control, environmental health management, environmental epidemiology, environmental microbiology, industrial hygiene and ventilation, nuclear medicine, occupational medicine, radiological health, respiratory biology, respiratory epidemiology, injury epidemiology, ergonomics, and solid waste management.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only, signature of instructor required.
Course Evaluations


EH300 Independent Study/ Tutorial
Fall 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. Opportunities are provided for independent studies in the fields of aerosol technology, air pollution control, environmental health management, environmental epidemiology, environmental microbiology, industrial hygiene and ventilation, nuclear medicine, occupational medicine, radiological health, respiratory biology, respiratory epidemiology, injury epidemiology, ergonomics, and solid waste management.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only, signature of instructor required.
Course Evaluations


EH300 Independent Study/ Tutorial
Spring 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. Opportunities are provided for independent studies in the fields of aerosol technology, air pollution control, environmental health management, environmental epidemiology, environmental microbiology, industrial hygiene and ventilation, nuclear medicine, occupational medicine, radiological health, respiratory biology, respiratory epidemiology, injury epidemiology, injury epidemiology, ergonomics, and solid waste management.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only, signature of instructor required.
Course Evaluations


EH300 Independent Study/ Tutorial
Spring
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. Opportunities are provided for independent studies in the fields of aerosol technology, air pollution control, environmental health management, environmental epidemiology, environmental microbiology, industrial hygiene and ventilation, nuclear medicine, occupational medicine, radiological health, respiratory biology, respiratory epidemiology, injury epidemiology, ergonomics, and solid waste management.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only, signature of instructor required.
Course Evaluations


EH300 Independent Study/ Tutorial
Spring 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. Opportunities are provided for independent studies in the fields of aerosol technology, air pollution control, environmental health management, environmental epidemiology, environmental microbiology, industrial hygiene and ventilation, nuclear medicine, occupational medicine, radiological health, respiratory biology, respiratory epidemiology, injury epidemiology, ergonomics, and solid waste management.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only, signature of instructor required.
Course Evaluations


EH300 Independent Study/ Tutorial
WinterSession
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. Opportunities are provided for independent studies in the fields of aerosol technology, air pollution control, environmental health management, environmental epidemiology, environmental microbiology, industrial hygiene and ventilation, nuclear medicine, occupational medicine, radiological health, respiratory biology, respiratory epidemiology, injury epidemiology, ergonomics, and solid waste management.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only, signature of instructor required.
Course Evaluations


EH303 Industrial Hygiene/Ergonomics Internship
Fall
Dr. R. Herrick, Dr. J. Dennerlein

20 credits
Field work. Normal working hours of the company, in addition to time required for relevant reading.

The student works in an industrial or similar workplace under the direction of a qualified and experienced industrial hygienist (a mentor). Generally, the first half of the six-month period is devoted to learning evaluation techniques (e.g., personal air sampling, direct reading instrumentation, ventilation measurements), and the second half to studying some specific hazard or problem in depth, and preparing material for presentation in the succeeding course, EH 267.
Course Note: Completion of the first year of the two-year master's degree program in Industrial Hygiene required; ordinal grading option only; no auditors. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH330 Field Work
WinterSession
Department Members

Time and credit to be arranged.

Supervised site visits and field research projects are available in medical, industrial hygiene, and environmental health departments of industries and governmental agencies. Students in the various programs in occupational health may receive one credit for one week of fieldwork in the WinterSession. Students participating in the industrial hygiene internship program receive 20 credits for fieldwork associated with their internship and should register for the internship through EH 273.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail option only; signature of instructor required. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH350 Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking.
advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


EH350 Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH350 Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH350 Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH350 Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH350 Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH350 Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH400 Non-Resident Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


EH400 Non-Resident Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH400 Non-Resident Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH400 Non-Resident Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH400 Non-Resident Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH400 Non-Resident Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work on the lines of fundamental or applied research in the department.
Course Note: Pass/ fail only; maximum of 20 credits; signature of instructor required.
Course Evaluations


EH504 Principles of Toxicology
Fall
Cross-listed at FAS as BPH-215 and at HMS as BPH-713.0

Dr. R. Wright
5 credits
Lectures, case studies, labs. Two 2-hour classes each week.

The course is designed to expose students to the principles and methods that should be used to determine whether a causal relationship exists between specific doses of an agent and an alleged adverse effect, observed primarily in humans. Integration of principles and methods of toxicology is extremely important since the primary purpose of toxicology is to predict human toxicity. Toxicological data obtained in animal studies must be placed in proper relationship to the exposure observed in the human population. The course deals with organ systems and whole organisms but relies on an understanding of the mechanistic approaches covered in EH508. Key target organs, selected classes of toxic agents and the application of toxicological principles are covered. Students are assigned a topic for a short presentation.
Course notes: Organic chemistry and mammalian physiology or equivalents required; instructor's signature required if student has not met prerequisites; required lab. This course may be taken for either 5.0 credits or 2.5 credits. To register for 2.5 credits, select section 02 (pass/fail grading option).


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH504 Principles of Toxicology
Fall
Dr. R. Wright

2.5 Credits
Lectures, case studies, labs. Two 2-hour classes each week.

Course Begins on Thursday, October 8, 2009

The course is designed to expose students to the principles and methods that should be used to determine whether a causal relationship exists between specific doses of an agent and an alleged adverse effect, observed primarily in humans. Integration of principles and methods of toxicology is extremely important since the primary purpose of toxicology is to predict human toxicity. Toxicological data obtained in animal studies must be placed in proper relationship to the exposure observed in the human population. The course deals with organ systems and whole organisms but relies on an understanding of the mechanistic approaches covered in EH508. Key target organs, selected classes of toxic agents and the application of toxicological principles are covered. Students are assigned a topic for a short presentation.
Course notes: Organic chemistry and mammalian physiology or equivalents required; instructor's signature required if student has not met prerequisites; required lab. This course may be taken for either 5.0 credits or 2.5 credits. To register for 5.0 credits, select section 01 (ordinal grading option).


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH506 Advanced Seminar in Aerobiology
Spring
Dr. D. Milton, Dr. J. McDevitt

2.5 credits
Course offered 2006-2007; alternate year course.
Seminars. One 2-hour session each week.

The advanced seminar in aerobiology will include structured reading and laboratories designed for advanced masters students and for doctoral students and presentations of students' work and research proposals with emphasis on implications for study design and data analysis. Each will be followed by submission of a brief written summary incorporating insights gained from class discussion. We will cover airborne infection, health effects of animal allergens, endotoxin, taxonomy of important allergenic and toxic fungi, exposure assessment, data analysis and case studies. The emphasis on structured reading and student work will vary from year to year depending on the needs of the students enrolled.
Course Activities: Presentations, written critiques, responses to presentations and a written research proposal for an aerobiological investigation relevant to public health.
Course Note: Signature of instructor required; EH256 or permission of instructor required. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH507 Environmental Exposure, Epidemiology and Risk Practicum
Fall
Dr. F. Laden, Dr. J. Levy, Dr. R. Herrick

5.0 credits
Seminars. One 3-hour session each week

The practicum is designed to allow Exposure, Epidemiology, and Risk (EER) Program students to integrate what they have learned and to apply this knowledge in the evaluation of a problem of importance. Each student must design and conduct an independent analysis of an environmental problem. Student projects must demonstrate analytical sophistication and critical interpretation of relevant science in support of decision making. Each student must prepare a written report and make an oral presentation of results to the EER faculty.
Course note: The practicum is restricted to students in the EER masters and doctoral program; instructor's signature required; ordinal grading option only. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH510 Fundamentals of Human Environmental Exposure Assessment
Fall
Dr. D. Macintosh, Dr. A. Lu

2.50 credits
Lecture and computer workshops. One 2-hour session each week.

This course is designed to provide the tools and foundations necessary to understand the fate and transport of environmental contaminants in various environmental media and to estimate their impact on human exposure. The course will consider human exposure assessment in the context of risk assessment. Physical-chemical properties of contaminants and environmental media will be considered as they relate to developing basic models of human exposure.

Course Activities: Class discussion, computer workshops, lectures, homework assignments, final exam.

Course Note: Calculus and chemistry required; course required for all EER Program students.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH512 Interdisciplinary Training in Pulmonary Sciences Part I
Fall
Dr. D. Tschumperlin, Dr. Q. Lu

2.5 credits
Lectures, seminars, case studies. Two 1-hour sessions each week.

The intersection of environment and health is by necessity an interdisciplinary focus. The most promising advances in lung biology and respiratory disease are resulting from teams of scientists with diverse disciplinary training, including biology, medicine, engineering, and physics. In addition to a strong foundation in a specific discipline, the ability to recognize and act upon opportunities presented by outside disciplines is a crucial skill. This course is designed to train scientists to approach lung biology and respiratory diseases with an interdisciplinary perspective, in particular by bridging the gap between life sciences and physical/engineering sciences. With a focus on laboratory sciences and on mechanistic levels of understanding, course materials will cover 3 main problem areas: asthma, air pollution, and lung infection. The course consists of weekly course-meetings (lectures and case-studies) plus weekly research seminars from the physiology program. Students will gain skills in recognizing the relative strengths and weaknesses of different disciplinary approaches applied to pulmonary sciences, in designing interdisciplinary experiments effectively, and in interpreting interdisciplinary results critically.

Course Notes: Instructor's signature required.


Course Evaluations


EH513 Interdisciplinary Training in Pumonary Sciences, Part II
Spring
Dr. D. Tschumperlin, Dr. Q. Lu

2.5 credits
Lectures, seminars, case studies. Two 1-hour sessions each week.

The intersection of environment and health is by necessity an interdisciplinary focus. The most promising advances in lung biology and respiratory disease are resulting from teams of scientists with diverse disciplinary training, including biology, medicine, engineering, and physics. In addition to a strong foundation in a specific discipline, the ability to recognize and act upon opportunities presented by outside disciplines is a crucial skill. This course is designed to train scientists to approach lung biology and respiratory diseases with an interdisciplinary perspective, in particular by bridging the gap between life sciences and physical/engineering sciences. With a focus on laboratory sciences and on mechanistic levels of understanding, course materials will cover 3 main problem areas: asthma, air pollution, and lung infection. The course consists of weekly course-meetings (lectures and case-studies) plus weekly research seminars from the physiology program. Students will gain skills in recognizing the relative strengths and weaknesses of different disciplinary approaches applied to pulmonary sciences, in designing interdisciplinary experiments effectively, and in interpreting interdisciplinary results critically.

Course Notes: Instructor's signature required.


Course Evaluations


EH515 Critical Readings: Mechanisms of Health Effects by Air Pollution
WinterSession
Dr. B. Gonzalez-Flecha, Dr. D. Dockery

1.25 credits
Not offered 2008-2009
Lectures, readings, case studies. Two 2-hour sessions each week during WinterSession

Reviews the mechanisms of toxicity of criteria air pollutants (ozone, nitrogen dioxide, particulate matter, sulfur dioxide, carbon monoxide and lead.) Presents current biological and epidemiological approaches to studying the health effects of air pollution. Particular focus on the pulmonary, cardiac and neurological health effects of air pollutants.

This is an interdisciplinary problem-based class. The students will work with selected scientific articles that present examples on how to study air pollutants. The central question/problem to be explored during the course will be "how to determine what causes health problems in individuals living in polluted cities." In the introductory class the students will be presented with a general introduction of criteria air pollutants, their sources, chemistry and toxicology, and they will be assigned review papers that discuss epidemiological, biochemical and toxicological methods to study the health effects of air pollutants. On the following classes the students will receive a brief review on each criteria pollutant and will discuss articles (case studies) presenting examples on how researchers in the fields of epidemiology, medicine and toxicology study the health effects of each individual pollutant. (6.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH516 Environmental Genetics
WinterSession
Dr. A. Ettinger

2.5 credits
Lectures, case studies. 3 hours per day over the course of 11 class days during Winter Session. Course will be held at the Cyprus International Institute in Cyprus, January 5 - 21.
The interaction between genes and environmental and/or occupational exposures plays a major role in disease development. This course will focus on the underlying science of gene-exposure interactions and will use examples of such interactions and their health consequences. Gene-environment interactions will be discussed using an epidemiologic approach to address how genetic polymorphisms can influence susceptibility to disease. This course will enable students to understand and apply findings of genetic association studies and will consist of detailed evaluation of specific examples of gene-exposure interactions and their health consequences, as well as their social implications.


Course note: No Auditors. HSPH degree candidates only.


Course Evaluations


EH517 Ecotoxicology
WinterSession
Dr. P. Koutrakis

2.5 Credits
Lectures, 3 hours per day over the course of 10 class days during Winter Session. Course will be held at the Cyprus International Institute in Cyprus. Jan. 3 - 16, 2008.

This course will enable students to understand the major underlying principles in ecotoxicology, predict the fate and behavior of major groups of environmental pollutants, describe dose-response relationships, eco-toxicity testing methods and toxic effects of pollutants in wildlife, and appraise the suitability of biomarkers and sentinel species for bio-monitoring pollutants. Furthermore, students will become able to critically analyze the strengths and weaknesses of ecological risk assessment, and they will have a chance to complete a basic ecological risk assessment.

Course note: No auditors. HSPH degree candidates only.

Course Evaluations


EH518 Air Pollution Modeling
WinterSession
Dr. S. Hanna

Winter Session
2.5 Credits
Lectures, Discussions, Case Studies, Training with Software. Eight 4-hour sessions.

The Course Dates TBA

This course focuses on a description of air pollution models widely used in general applications by several agencies. The scientific basis of air pollution models is reviewed. A wide range of models is covered, including models for smoke stack plumes, for hazardous gas accidents, for traffic emissions, and for regional ozone and PM. A more in-depth review is given of the EPA's AERMOD model, which is used to calculate pollutant concentrations downwind of industrial stacks. One-quarter of the lecture period are devoted to hands-on software training with AERMOD, using real-world scenarios.

Course Note: EPA Technical manuals and users guides for their air quality models will be made available via web links.

Course Evaluations


EH520 Research Design in Environmental Health
Spring
Dr. J. Schwartz

2.5 Credits
Lectures. One 2-hour session each week.

The seminars consist of student presentation of plans for collection and analysis of data, with discussion by students and faculty. Preparatory work is done under tutorial arrangements with members of the faculty. The emphasis is on conceptual issues necessary for the development of a feasible and informative study.

Course Activities: Individual student paper and presentation, class discussion, oral critique of another student's research proposal and student and faculty critiques.

Course Note: This course is aimed primarily at environmental health doctoral students.

Course Evaluations


EH521 Environmental Cardiology
Fall 2
Dr. D. Dockery, Dr. A. Peters

1.25 Credits
Lecutres. One 2-hour lecture each week.

The course will assess the impact of the environment on the onset and exacerbation of cardiovascular diseases. Environmental exposures that have been implicated to impact cardiovascular disease are predominantly air pollution, second hand smoke, noise and heat. The course will present teaching examples showing the study designs applied in environmental epidemiology focusing on cardiovascular disease. Short-term health effects as well as health effects of continuous exposure over decades on the cardiovascular system by these environmental exposures will be demonstrated. The course will explore the evidence for the biological plausibility of the observed health effects and will highlight recent developments in this area concerning gene-environment interactions.

Course Note: Minimum enrollment of 5 required for course to be offered.

Course Evaluations


EH522 Indoor Environmental Quality and Health
Fall
Dr. P. Demokritou, Dr. J. Spengler

2.5 Credits
Lectures. One 2-hour session each week.

This course aims to introduce students to the concepts necessary for analyzing the indoor environments and help them to understand and address indoor environmental quality problems in the modern built environments and the link to health, comfort and productivity of the occupants. Emphasis is placed on understanding the nature of indoor air quality; indoor air pollutants, including their sources and health effects; generation and transport of pollutants; modeling of IAQ in buildings; modern building systems including Heating Ventilation and Air conditioning systems as well as air cleaning systems; IEQ regulations, guidelines and building standards; and procedures for assessing indoor air quality issues. This course aims to introduce students to the concepts necessary for analyzing the indoor environments and help them to understand and address indoor environmental quality problems in the modern built environments and the link to health, comfort and productivity of the occupants. Emphasis is placed on understanding the nature of indoor air quality; indoor air pollutants, including their sources and health effects; generation and transport of pollutants; modeling of IAQ in buildings; modern building systems including Heating Ventilation and Air conditioning systems as well as air cleaning systems; IEQ regulations, guidelines and building standards; and procedures for assessing indoor air quality issues.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EH523 Work, Health, and Productivity
WinterSession
Dr. E. McNeely

2.5 Credits
Course not offered 2009-2010; Offered alternate years
Lectures, seminars, case studies. Five 3-hour sessions per week.

This course provides a broad foundation for evaluating the health care needs of employees, including both work-related issues and general health promotion. Through seminar discussions and field experiences, the participants consider the many frames for thinking about worker health, such as the perspectives of employees, managers, companies, insurers, health care providers and labor groups.

The goal of this class is to develop a sensible approach to the assessment, planning and evaluation of employee health programs. The class offers individuals who are interested in workers' health care policy and economics, the opportunity to come together in discussion and purpose to propose innovation in the current system of employee health care.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.





Course Evaluations


EH524 Water and Human Well-being
Fall
Dr. J. Briscoe

2.5 Credits
Lectures, case studies. One 2-hour session each week.

Societies blessed with reliable, adequate supplies of good quality water have developed better than societies not so blessed. In order to provide adequate water security, societies invest in infrastructure and institutions to manage water resources more effectively, and to provide better water services. The course will explore the paths taken by now-rich countries and examine the consequences for human well-being, and will assess what is and what is not relevant from this experience for developing countries. Discussions will be organized around real-world case studies in which the instructor has been an active participant. The course will take an inter-disciplinary view and employ tools of history, hydrology, engineering, economics, political science and epidemiology.

Course Activities: Lecture, case studies and active learning through class participation. Brief written assignments evaluating select case studies and a term project relating to a real-world water intervention.

Course Evaluations


EPI200 Principles of Epidemiology
Fall 1
Dr. J. Buring

2.5 credits
Lectures, seminars. Two 1-hour lectures and one 2-hour seminar each week.

Introduces the basic principles and methods of epidemiology. Lectures are complemented by seminars devoted to exercises or to the discussion of current examples of epidemiologic studies.
Course Activities: Lectures, seminar participation, midterm, final examination.
Course Note: Thursday or Friday lab required. Credit is not given for more than one of EPI 200, EPI 201, EPI 208, or EPI500

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI200R Principles of Epidemiology Repeat
Spring 1
Dr. E. F. Cook

2.5 credits
Independent Study

Open only to students who have failed the core course, and must repeat it. Students must sign up for the section with the instructor from whom they took the original course.
Course Note: Completed independent study contract is required at the time of registration; pass/fail only; signature of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI200R Principles of Epidemiology Repeat
Spring 2
Dr. E. F. Cook

2.5 credits
Independent Study

Open only to students who have failed the core course, and must repeat it. Students must sign up for the section with the instructor from whom they took the original course.
Course Note: Completed independent study contract is required at the time of registration; pass/fail only; signature of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI201 Introduction to Epidemiology: Methods I
Fall 1
M. Hernan

2.5 credits
Lectures, labs. Two 2-hour sessions each week, one 2-hour lab each week.

EPI201 introduces the principles and methods used in epidemiologic research. The course discusses the conceptual and practical issues encountered in the design and analysis of epidemiologic studies for description and causal inference. The final exam requires the application of the learned skills to a real problem in epidemiology. EPI201 is the first course in the series of methods courses designed for students majoring in Epidemiology or Biostatistics, and those interested in a detailed introduction to the design and conduct of epidemiologic studies. Students who take EPI201 are expected to take EPI202 (Methods II).

Course Note: Thursday or Friday lab required. Credit is not given for more than one of EPI 200, EPI 201, EPI 208, or EPI500; ordinal grading option only; no auditors.

Course Evaluations


EPI201R Introduction to Epidemiology Repeat
Spring 1
Dr. E. F. Cook

2.5 credits
Independent Study

Open only to students who have failed the core course, and must repeat it. Students must sign up for the section with the instructor from whom they took the original course.
Course Note: Completed independent study contract is required at the time of registration; pass/fail only; signature of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI201R Introduction to Epidemiology Repeat
Spring 2
Dr. E. F. Cook

2.5 credits
Independent Study

Open only to students who have failed the core course, and must repeat it. Students must sign up for the section with the instructor from whom they took the original course.
Course Note: Completed independent study contract is required at the time of registration; pass/fail only; signature of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI202 Elements of Epidemiologic Research: Methods II
Fall 2
Dr. M. Mittleman

2.5 credits
Lectures, seminars. Two 2-hour sessions and one 2-hour seminar each week.

Introduces elements of study design, data analysis and inference in epidemiologic research. Principles and methods are illustrated with examples, and reviewed through homework and in-class exercises. May serve as an introduction to more advanced study or as a concluding course for those desiring a working knowledge of epidemiologic methods.

Course Note: EPI 201, EPI500, or EPI208 required - This course is intended to by taken in conjunction with EPI201 to complete the equivalent of a full semester course in Epidemiologic Methods. BIO 201, or BIO 202 and 203; or BIO 206 and BIO 207, BIO 208 or BIO 209 required - concurrent enrollment permitted. Thursday or Friday lab; sign up for appropriate section at first class meeting.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI202 Elements of Epidemiologic Research
Summer 2
Dr. M. Mittleman

2.5 credits
Lectures, seminars. Five 2-hour sessions each week.

Introduces elements of study design, data analysis and inference in epidemiologic research. Principles and methods are illustrated with examples, and reviewed through homework and in-class exercises. May serve as an introduction to more advanced study or as a concluding course for those desiring a working knowledge of epidemiologic methods.
Course Note: EPI 200, EPI 201, EPI208, or EPI500 required - concurrent enrollment permitted; BIO 200; or BIO 201; or BIO 202 and 203; or BIO 205; or BIO 219; or BIO 206 and BIO 207, BIO 208 or BIO 209 required - concurrent enrollment permitted.



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI203 Study Design in Epidemiologic Research
Spring 2
Dr. A. Walker

2.5 credits
Lectures. Two 2-hour sessions each week.

Beginning with the randomized clinical trial as a paradigm, this course examines common problems in the design, analysis, and interpretation of observational studies. Cohort and case-control studies are the focus of the discussion, but not to the exclusion of other designs. Problems of exposure and disease definitions, time-dependent effects, confounding, and misclassification are considered in the light of data sources typically available. Relevant statistical methods are introduced but not developed in detail.
Course Activities: Review of published studies, class discussion.
Course Note: EPI 202 and BIO 200, BIO 201, or BIO202 and BIO203, or signature of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI204 Analysis of Case-Control and Cohort Studies
Spring 2
TBA

2.5 credits
Lectures, seminars, labs. Two 2-hour sessions each week.

Examine, through practical examples, analysis of case-control and cohort studies using, primarily, conditional logistic and Cox regression model etiologic studies. Explore analytic approaches in the presence of missing data, confounding, and interaction. Emphasize analysis and interpretation of results in the context of research question and study design. Familiarity with SAS is desirable.
Course Activities: Written group projects, class discussion, quizzes, homework.
Course Note: BIO11 or BIO113 and EPI200, EPI201 or EPI208, and EPI202 required. Concurrent enrollment permitted. BIO210 required. Concurrent enrollment permitted. Lab optional.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI205 Practice of Epidemiology
Fall
Dr. E. Rimm, Dr. M. Stampfer, Dr. L. Mucci, Dr. G. Curhan

2.5 credits
Seminars, tutorials. One 2-hour tutorial each week during Fall 1 period and one 2-hour seminar each week during Fall 2 period.

The seminars consist of student presentations of plans for collection and analysis of epidemiological data, with discussion by students and faculty. Preparatory work is done under tutorial arrangements with members of the faculty. The emphasis is on conceptual issues necessary for the development of a feasible and informative epidemiological study.
Course Activities: Individual student paper and presentation, class discussion, and student and faculty critiques.

Course Note: This course is aimed primarily at epidemiology doctoral students; EPI201, EPI202, EPI203 and EPI204; signature of instructor required; ordinal grading option only. (5.06) class size is limited.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.



Course Evaluations


EPI207 Advanced Epidemiologic Methods
Fall 1
Dr. M. Hernan, Dr. J. Robins

2.5 credits
Lectures. Two 2-hour sessions and one 2-hour lab each week.

Provides an in-depth investigation of statistical methods for drawing causal inferences from observational studies. Informal epidemiologic concepts such as confounding, selection bias, overall effects, direct effects, and intermediate variables will be formally defined within the context of a counterfactual causal model and with the help of causal diagrams. Methods for the analysis of the causal effects of time-varying exposures in the presence of time dependent covariates that are simultaneously confounders and intermediate variables will be emphasized. These methods include g-computation algorithm estimators, inverse probability weighted estimators of marginal structural models, g-estimation of structural nested models. As a practicum, students will reanalyze data sets using the above methods.
Course Activities: Class discussion, homework, practicum and final examination.

Course Note: EPI204, BIO210 and EPI289, or BIO233, or signature of instructor required; familiarity with logistic regression and survival analysis is expected; lab time will be announced at first meeting. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI208 Introduction to Clinical Epidemiology
Summer
Dr. J. Katz, Dr. E. F. Cook, Dr. D. Singer, Dr. H. Baer

5 credits
Lectures, seminars, case studies. Five 2-hour sessions each week.

This course is an introductory-level course and covers the principles and methods used in traditional and clinical epidemiologic research through a series of lectures, exercises, seminars, workshops and presentations. This course is targeted at individuals planning to conduct clinical research.
Course Activities: Written assignments, computer exercises, seminar discussion; each student is required to develop a study proposal that addresses a specific clinical problem and to formally present this proposal to the class. These proposals are then written in grant application format as the final paper for the course. Seminars are held during scheduled class time.

Course Note: For participants in the Summer Program in Clinical Effectiveness only; no auditors.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI213 Epidemiology of Cancer
Spring 1
Dr. E. Giovannucci, Dr. L. Mucci

2.5 credits
Lectures. Two 2-hour sessions each week.

The aim of this course is to present an overview of the basic concepts and issues central to cancer epidemiology. We will consider the descriptive epidemiology of cancer and discuss the implications of the biology of cancer for identification of risk factors. We present topics both with respect to key cancer exposures, including smoking, radiation, nutrition, and hormones, and also highlight selected malignancies.

Course Activities: Active class participation, descriptive epidemiology of a specific cancer site, a final review paper.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI215 Adv. Topics in the Analysis of Case Control and Cohort Studies
Spring 2
Dr. E. Cook, Dr. P. Kraft, Dr. E. Tchetgen

2.5 Credits
Course Not Offered 2009-2010
Lectures, labs. Two 2-hour sessions each week.

This course primarily extends the applications of parametric regression models covered in EPI204 to address additional and related analytic issues encountered in epidemiologic research. Topics include techniques for modeling continuous and polychromous exposures, methods to account for missing data, doubly-robust modeling, and issues involved in high dimensional data analysis, risk prediction, and sample size calculations. Emphasis is on applications of interpretations of results with limited introduction to theory that underlies these techniques. Familiarity with SAS is desirable.

Course Activities: Class discussion, quizzes, homework.

Course Note: EPI204 required. Lab optional.

Course Evaluations


EPI216 Epidemiology in Public Health Practice
Spring 1
Dr. R. Dicker

2.5 credits
Case studies. One 3-hour session each week.

The course uses case studies to teach the principles and practice of field epidemiology, ranging from surveillance to descriptive epidemiology to outbreak investigation to analytic methods. The course focuses on the use of sound epidemiologic judgment, particularly when epidemiologic theory and practical considerations conflict. Following this course, the student will be familiar with the principles of epidemiology relevant to public health professionals, and should be able to apply those principles to address public health problems in the community.
Course Note: EPI 200, EPI 201, or EPI 208 required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI219 Assessment Concepts and Methods in Psychiatric Epidemiology
Fall 2
Dr. D. Blacker

2.5 credits
Lectures, laboratory/practice sessions. One 2-hour lecture and one 1-hour laboratory/practice session each week.

Presents the application of basic epidemiologic and psychometric concepts and methods in psychiatric research. Topics include: measurement theory, reliability, validity, screening, and diagnostic classification procedures, as they specifically relate to psychiatric research. The course is in the psychiatric epidemiology track and is intended primarily for students interested in conducting mental health research.
Course Activities: Class discussion, brief homeworks, class project with oral presentation and final paper.
Course Note: Students should be familiar with the major forms of psychopathology, basic epidemiologic research methods, and introductory statistics; EPI 200, EPI 201 or EPI 208 and BIO 200 or BIO 201 or BIO 200s and BIO 200t required or consent of instructor; lab or section time to be arranged at first meeting. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI220 Psychiatric Diagnosis in Clinic and Community Populations
Spring 2
Dr. J. Smoller, Dr. M. Mimiaga

2.5 Credits
Offered in 2008-2009. Offered alternate years.
Seminars. Lab. One 2-hour class session each week and One 2-hour lab each week.

Focuses on interview schedules designed to diagnose psychiatric disorders in clinical settings and household surveys. The course provides practical experience in differential diagnosis, in the administration of different kinds of interview schedules, and in analysis of responses. The course is designed primarily for students considering a career in mental health research. The course is an applied, mid-level course in the psychiatric epidemiology track.

Course Activities: Class discussion, verbal and written reports on practicum experience.

Course Note: Students should have an understanding of the major forms of psychopathology; introductory statistics and epidemiology; clinical or research experience with psychopathology or prior psychiatric epidemiology coursework; signature of instructor required. BIO200 or BIO201 or equivalent, EPI200 or EPI201 or equivalent.

Course Evaluations


EPI221 Pharmacoepidemiology
Fall 2
Dr. A. Walker

2.5 credits
Lectures. Four 2-hour lectures each week.

Within the framework of formal epidemiologic analysis, this course covers inference about the effects of pharmaceuticals from case reports, case series, vital statistics and other registration schemes, cohort studies, and case-control studies. Decision-making with inadequate data is examined from the perspectives of manufacturers and of regulators. Students are graded on the basis of group projects. This course is intended primarily for students wishing to pursue a career in the pharmaceutical industry or in national regulatory bodies, but may have more general interest as an applied mid-level course with a heavy methodological emphasis.
Course Activities: Written and oral group projects, individual class presentations, class discussion.

Course Note: Knowledge of epidemiology at the level of EPI 202 and a basic understanding of drug use and nomenclature are assumed; completion of EPI203 preferred; enrollment limited to 25 students; signature of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI222 Genetic Epidemiology of Diabetes and its Complications
Spring 2
Dr. F. Hu, Dr. A. Doria

2.5 credits
Course offered 2008-2009; taught alternate years.
Seminar, case studies, laboratories. Two 2-hour seminars each week.

The genetics of diabetes and its complications, together with the descriptive epidemiology of these conditions, will be used to illustrate the process of generating etiologic hypotheses that can be studied by the methods of genetic epidemiology. Techniques of molecular genetics relevant to epidemiologic studies will be reviewed and demonstrated. Data sets that include genotype information will be analyzed with an emphasis placed on the examination of various gene/environment interaction.
Course Note: EPI 202 required; lab or section time to be announced at first meeting; ordinal grading option only. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI223 Cardiovascular Epidemiology
Fall 2
Dr. D. Mozaffarian

2.5 credits
Lectures, in-class presentations. Two 2-hour sessions each week.

This course reviews the epidemiology of cardiovascular disease, including the major cardiovascular diseases, related conditions, emerging risk factors, and current controversies. The principal methods used, and their limitation, will also be discussed. Both historically important and current research will be presented. Grades are based on participation in class discussions, brief written paper critiques, and an in-class presentation. There is no midterm or final exam.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI224 Cancer Prevention
Spring 2
Dr. L. Frazier, Dr. C. Stein

2.5 credits
Lectures, case studies. Two 2-hour session each week

The course will help students develop a framework for analyzing and designing cancer prevention interventions to reduce the burden of cancer. Approaches to cancer prevention will be reviewed with the principal emphasis on primary prevention. The lectures and readings will examine different theoretical and practical issues around effectiveness, feasibility, and sustainability of interventions, including theories of behavior change, population vs. high-risk approaches, risk perception and communication, and barriers to implementation. Through problem-based learning exercises, students will review the strategies for cancer prevention in the areas of tobacco control, physical activity and obesity, and screening and vaccines, in addition to other topics. We will emphasize the timing of prevention in the context of the natural history of disease etiology (e.g. breast cancer) and consider population-based approaches to prevention (e.g. skin cancer). Strategies for prevention on multiple levels will also be examined. Levels of intervention from action by health care providers (e.g., counseling and screening), regulatory policy, social structural changes, and individual behavior changes will be emphasized. Key components necessary for prevention policy will include an adequate knowledge base, social strategies, and political will. Students will have homework assignments to collect and summarize information based on case studies, which will be used to develop a cancer prevention intervention as a final project. Grades will be based on class participation, short homework assignments and a final project paper and presentation.
Course Note: Requirement in the Cancer Education Program.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations

Course Evaluations


EPI228 Oral Epidemiology
Fall
Dr. T. Zavras

2.5 credits
Course offered 2009-2010, offered alternate years.
Lectures, case studies. One 2-hour session each week.

This course will first discuss the principal measures and methods of epidemiology as they apply to oral conditions; then the distribution, etiology and risk factors for dental caries, periodontal diseases, cleft lip and palate, oral cancer, soft tissue lesions and malocclusions will be studied. The third part of the course links oral epidemiology data to health policy issues:e.g. community preventive dentistry programs, national health care policy, infection control, and health services outcome research.
Course Activities: Class discussion, reading homework, written assignments, midterm and final examinations.
Course Note: EPI 200, EPI 201 or EPI 208 required (concurrent enrollment permitted).


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI229 Ophthalmic Epidemiology
Fall 2
Dr. D. Schaumberg

1.25 credits
Offered 2008-2009, offered alternate years.
Lectures, seminars, discussion. One 2-hour session each week.

The blinding eye disease macular degeneration has emerged as a paradigmatic example of the interplay between genetic predisposition and lifestyle risk factors in causing chronic disease. This course will use the example of macular degeneration as a jumping off point to study the epidemiology of some of the leading causes of blindness and visual impairment. Other diseases will include cataract, glaucoma, diabetic retinopathy, and dry eye disease, and possibly others. Students will obtain knowledge of the leading causes of blindness and visual impairment throughout the world, the burden of disease, the large socioeconomic and gender inequities globally, and what is known about major risk factors for eye diseases. The course will also touch on strategies to study gene-environment interactions, as well as some statistical issues related to correlated data structures that arise when studying eye disease--e.g. should we study people or eyes?--and how to begin to translate research findings into public health action.

Course Note: EPI 200, EPI 201 or EPI 208 preferred.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI233 Research Synthesis & Meta-Analysis
Spring
Dr. C. Hsieh, Dr. J. Goodman

2.5 credits
Seminars. One 1.5-hour session each week.

Concerned with the explosion of biological data for etiologic inquiry and the use of existing data to inform public health decision making, the course focuses on research synthesis and meta-analysis. We will review the principles and methods for combining epidemiology studies and introduce how other types of scientific evidence, such as toxicology or mode-of-action data, can be incorporated using weight of- evidence analyses. This course will emphasize the use of critical reviews and meta-analysis to explore data and identify sources of variation among studies.

Course Activities: Students will learn the principles of a systematic review, to use existing meta-analys is software to apply principles outlined in the course on example data sets, and, on a topic of their choice, to conduct a critical review or meta-analysis that appropriately weights effect estimates in each study, assesses uncertainty, and incorporates other kinds of scientific data in the overall analysis.

Course Note: EPI200 or EPI201 and BIO200, BIO201, or BIO202 and BIO203 .

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.


Course Evaluations


EPI235 Epi Methods in Health Services Research
Spring 1
Dr. S. Setoguchi-Iwata

Course offered 2009-2010; offered alternate years.
2.5 credits
Lectures, case studies. Two 2-hour lectures each week.

This course is designed to introduce Epidemiology students to the application of standard epidemiologic methods to Health Services Research. The course helps students to recognize the principles of Epidemiology in Health Services Research, and understand the terminology and methods specific to the field. Threats to validity including selection bias, confounding, information bias, and methods for their control will be discussed in a variety of settings emphasizing practical considerations. Lectures include recent or ongoing case studies and examples from the literature. Topics include strategic planning, quality management, risk-adjustment, benchmarking, outcomes and effectiveness research, and program evaluation.
Course Note: EPI202 and BIO 200 or BIO201 required or signature of instructor.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI236 Analytical Aspects of Clinical Epidemiology
Summer 1
Dr. E. F. Cook

5 credits
Lectures, seminars. Ten 2-hour sessions each week.

This course examines some features of study design, but is primarily focused on analytic issues encountered in clinical research. These include techniques for stratified analysis, regression modeling, propensity scores, matching and recursive partitioning. Emphasis is placed on the use of these techniques for the control of confounding and the development of clinical prediction rules. The focus of this course is on applications and interpretations of results with limited introduction to theory that underlies these techniques.
Course Activities: Seminars are scheduled during regular class time. Students must develop a written summary of the analysis of a clinical data set based on the results of daily computer exercises.
Course Note: EPI 208 and BIO 206 and (BIO 207 or BIO 208 or equivalent courses) required; signature of instructor required.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI240 Use of Biomarkers in Epidemiologic Research
Spring 1

Dr. S. Hankinson, Dr. S. Tworoger
1.25 credits
Course offered 2008-2009; offered alternate years.
Lectures, case studies. One 2-hour session each week.

The purpose of this course is to provide students with an overview of the issues pertinent to the collection, measurement, and statistical analysis of biomarker data. The course aims to address general principles within the context of relevant examples. Topics to be covered include study-design considerations, sample storage, sources of laboratory variability, assay evolution and use of pooled samples, among others.
Course Activities: Class discussion, final project.
Course Note: EPI 200, EPI 201 or EPI 208 required; minimum enrollment of 10 students required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI241 Measuring Health Status
Fall 2
TBA

2.5 credits
Course not offered 2008-2009
Lectures. One 2-hour session each week.

Examines methodologic issues related to measures of health and disease status encountered in clinical research. Topics to be covered include instrument development, scaling, space assessment of reliability, validity and responsiveness to change; principal component analysis and factor analysis; diagnostic test evaluation.
Course Activities: Class discussion, examination, paper.
Course Note: Minimum enrollment of 10 students required.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI242 Seminar in Applied Research in Clinical Epidemiology
Fall
Dr. D. Singer, Dr. E. Orav, Dr. E. F. Cook (Section 1)

Dr. E. F. Cook (Section 3)
1.25 credits for Fall semester; 1.25 credits for Spring semester
Seminars. One 1.5-hour session each week.

This seminar serves as a forum for students' clinical epidemiologic research. In the process, students are exposed to a variety of research designs, analytic strategies, and content areas. There is active class discussion. Faculty emphasize methodologic issues pertinent to the class research presentation.
Course Activities: Student presentation or written assignment.
Course Note: Must register in each appropriate semester; separate grade given at the end of each semester; signature of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI242 Seminar in Applied Research in Clinical Epidemiology
Spring
Dr. D. Singer, Dr. E. Orav, Dr. E. Cook (Section 2)

Dr. E. F. Cook (Section 4)
1.25 credits for Fall semester; 1.25 credits for Spring semester
Seminars. One 1.5-hour session each week.

This seminar serves as a forum for students' clinical epidemiologic research. In the process, students are exposed to a variety of research designs, analytic strategies, and content areas. There is active class discussion. Faculty emphasize methodologic issues pertinent to that presentation.
Course Activities: Student presentation or written assignment.
Course Note: Must register in each appropriate semester; separate grade given at the end of each semester; signature of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI244 Genetic Epidemiologic Methods for Psychiatric & Other Disorders
Spring 1
Dr. S. L. Santangelo, Dr. D. Pauls

2.5 Credits
Offered alternate years. Not Offered 2009-2010.
Lectures. One 3-hour session each week.

Designed to introduce students to classical and current research methodology for genetic epidemiologic studies of complex (non-Mendelian) disorders using examples drawn from the psychiatric genetics literature. Topics include issues in phenotype definition, design and analysis of family, twin and adoption studies, segregation analysis, linkage analysis, and association study methods. Students will gain direct experience in carrying out linkage and association analyses using different approaches and analytic packages. Laboratory sessions will be devoted to gene-finding methods and discussion of the technical details of executing the relevant computer programs and interpretation of results. This is one of the courses on the psychiatric epidemiology track, but it may also be of interest to students interested in methods for studying any disorders with complex genetic inheritance.

Course Activities: Lectures, class discussion, homework assignments, labs devoted to computer analyses of data, interpretation, oral or written presentation of results of data analysis.

Course Notes: 1, 5: Students should have an understanding of basic epidemiologic research methods, introductory biostatistics and probability; enrollment limited to 25 students.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI245 Cardiovascular Epidemiology II - Reading the Literature
Spring
Dr. D. Mozaffarian

1.25 Credits
Seminars. One 2-hour session each week.

This course builds upon concepts and methods learned in cardiovascular Epidemiology I (taught in Fall), with a focus on reading and evolution of scientific literature. Coursework will be taught in a seminar-style format, with a focus each class on reading and evaluating relevant original published manuscripts in cardiovascular epidemiology. Students will actively take part in the biweekly manuscript critiques, including leading of at least one critique during the course. The focus will be on development of the student's ability to consider and evaluate scientific investigations in term of methods, strengths and limitation (e.g. related to study design, classification and exposure and outcome, bias/confounding, generalizability, etc) and implications.

Course Requirements: successful completion Cardiovascular Epidemiology I (EPI223) or approval of the course instructor. Enrollment is limited to 10 students.

Course Evaluations


EPI246 Applied Biomarkers in Cancer Epidemiology
Fall 2
Dr. E. Schernhammer

2.50 credits
Not Offered 2009-2010. Alternate year course.
Lectures, discussions. Two 2-hour sessions each week

The focus of this course is on application and interpretation of cancer studies using biomarkers. Topics include biomarkers of exposure, biomarkers related to metabolism/activation and other biological pathways, intermediate/surrogate endpoints, markers of early cancer detection and prognosis. Examples are discussed in each topic to demonstrate different issues in the interpretation of results. Class will be split into one hour lectures and one hour discussions of assigned readings.

Course Activities: Class discussion, one oral presentation, homework assignments, group project, final exam.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI247 Epidemiologic Methods Development - Past and Present
Fall 2
Dr. M. Mittleman

2.5 credits
Lectures. Two 2-hour sessions each week.

This course aims to provide students with a strong foundation in understanding the theoretical basis of currently used epidemiologic methods and also to help students acquire an understanding of the process of developing new approaches. The course will review the theoretical basis of modern epidemiology by reviewing landmark papers in the development of epidemiologic methods. Students will review classic papers that introduced important theoretical and methodological advances in the field.
Course Note: EPI289 or Signature of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI249 Molecular Biology for Epidemiologists
Fall 1
Dr. I. De Vivo

2.5 credits
Lectures. Two 2-hour sessions each week.

This course offers an overview of molecular biology and presents molecular biological concepts and techniques commonly used in the laboratory and in epidemiological research. Topics include the structure of DNA and genes, DNA replication, transcription and RNA translation. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI252 Infections and Cancer
Spring 2
Instructor TBA

2.50 credits
Course not offered 2008-2009; offered alternate years.
Lectures, seminars, case studies. Two 2-hour sessions each week.

This course reviews the epidemiology and public health impact of viral and other infectious agents associated with malignancy. The role of host response and the use of serology and viral probes as risk markers are discussed. A related disease or unknown agent is discussed as a case study.
Course Note: EPI 213 required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI254 The Epidemiology of Aging
Spring 2
Dr. F. Grodstein

1.25 credits
Course Not Offered 2009-2010. Offered Alternate Years.
Lectures. One 2-hour session each week.

This course will cover epidemiologic concepts and methods related to diseases of aging as well as general health issues in the elderly. Topics will include the epidemiology of Alzheimer's Disease; pharmacoepidemiology in the elderly; methodologic dilemmas in such research; as well as others.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI255 Epi of HIV,Part I:Etiology, Natural History & Transmission
Fall 2
Dr. G. Seage

2.5 credits
Course offered 2009-2010; Offered alternate years.
Lectures. One 3-hour session each week.

This course is designed to introduce students to the epidemiology of HIV infection. It is designed for those students with a keen interest in both HIV/AIDS and epidemiologic methods. This course will survey state-of-the-art knowledge of the epidemiology of HIV infection and will emphasize epidemiologic principles and methods; including studies of the etiology of AIDS, estimation of the incidence and prevalence of HIV and AIDS, natural history and survival. The use of appropriate study designs and potential sources of bias will be discussed, with a focus on observational designs. This course will provide the student with experience in the critical review of epidemiologic studies in this area.
Course Activities: Homework assignments will consist of study questions, study critiques, and an in-class exam. These assignments constitute 100% of the grade and are due on the day of the discussions.
Course Note: EPI200, EPI201, or EPI208 required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI256 Epi of HIV, Part II: Therapeutic & Prevention Interventions
WinterSession
Dr. G. Seage

2.5 credits
Course not offered 2009-2010; offered alternate years.
Lectures. Three 3-hour sessions each week.

This course is designed to introduce students to the design and conduct of HIV therapeutic and prevention interventions. It is designed for those students with a keen interest in both HIV/AIDS and epidemiologic methods. This course will survey state-of-the-art knowledge of the epidemiology of HIV infection and will emphasize epidemiologic principles and methods including the design and conduct of ethical HIV intervention trials. The use of appropriate study designs and potential sources of bias will be discussed. This course will provide the student with experience in the development of a research proposal.
Course Activities: Grades will be based on a research proposal describing a therapeutic or prevention trial.
Course Note: EPI 200, EPI201, EPI208 and EPI255 or signature of instructor required. Course meets Monday, Wednesday, Friday from 9 am to 12 pm during WinterSession. On 1/20 and 1/23 the course will meet from 9 am to 1:30 pm. (5.06)



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI257 Advanced Seminar in Cancer Epidemiology
Fall 2
Dr. R. Tamimi

2.5 credits
Course Not Offered 2009-2010
Interactive seminars. Two 2-hour sessions each week.

This course is an advanced seminar in current cancer research. The goal of this course is to present an integrated view of current issues central to cancer epidemiology. We will build on knowledge gained in other courses and cover cancer sites not typically discussed in other courses. The course will take a global perspective on cancer epidemiology, and will emphasize the integration of knowledge from other courses. The course is intended for graduate students who have a research focus in, or a strong interest in cancer epidemiology and cancer prevention. Meetings are expected to be participatory discussions about the current status and future directions for research in the selected areas.

Course Note: Enrollment limited; pass/fail only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI260 Mathematical Modeling of Infectious Diseases
Spring 2
Dr. M. Lipsitch

2.5 credits
Course offered 2008-2009. Offered alternate years.
Lectures, seminars. Two 2-hour sessions each week.

This course will cover selected topics and techniques in the use of dynamical models to study the transmission dynamics of infectious diseases. Class sessions will primarily consist of lectures and demonstrations of modeling techniques. Techniques will include design and construction of appropriate differential equation models, equilibrium and stability analysis, parameter estimation from epidemiological data, determination and interpretation of the basic reprodutive number of an infection, techniques for sensitivity analysis, and critique of model assumptions. Specific topics will include the use of age-seroprevalence data, the effects of population heterogeneity on transmission, stochastic models and the use of models for pathogens with multiple strains. This course is designed for students with a basic understanding of mathematical modeling concepts who want to develop models for their own work.
Course Note: Previous course in calculus is required; EPI225, EPI285, EPI501, or permission of instructor required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI269 Epidemiological Research in Obstetrics and Gynecology
Fall 2
Dr. K. Terry, Dr. D. Cramer, Dr. K. Michels

2.5 credits
Lectures. Two 2-hour sessions each week.

This course will provide an overview of the current research in reproductive epidemiology. The course will cover epidemiologic research in the areas of contraception, infertility, pregnancy, menopause, and both benign and malignant gynecological conditions. Students will be introduced to methods used in reproductive epidemiology and learn how to critically evaluate results from epidemiologic studies in obstetrics and gynecology. An overview of the clinical and physiological underpinnings of particular topical areas will be provided.
Course Note: EPI 200, EPI 201 or EPI 208 or signature of instructor required. (6.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI270 Advanced Reproductive Epidemiology
Spring 2
Dr. J. Rich Edwards, Dr. M. Hacker

1.25 credits
Lectures, seminars. One 2-hour session each week.

This course is an advanced seminar in reproductive epidemiologic methods. It is intended for graduate students who have a research focus, or a strong interest, in reproductive epidemiology. The course will cover methodological challenges in analyzing and interpreting epidemiologic data on reproductive outcomes including fertility, fetal development, complications of pregnancy, pregnancy outcomes, the controversial role of birthweight and perinatal status in determining short-term and long-term health outcomes of offspring, and the implications of reproductive health status for chronic disease in women. The course will be led by Drs. Rich-Edwards and Hacker, with faculty joining to present methodological cases. Students must read the case materials before class and be prepared for active class discussion. Pass/fail grading will be based on class participation.

Course Note: EPI 269 or equivalent required; instructor's signature required if student has not completed prerequisites; pass/fail grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI271 Propensity Score Analysis:Theoretical & Practical Considerations
WinterSession
Dr. T. Kurth , Dr. J. D. Seeger

1.25 Credits
Lectures, Computer Lab. Five 2-hour lectures and four 2-hour computer lab sessions

This course introduces basic and advanced theory underlying propensity score analyses and provides practical insights into the conduct of studies employing the method. Course readings will include propensity score theory as well as applications. Lectures are complemented by computer lab sessions devoted to the mechanics of estimating and using the propensity score as a tool to control for confounding in observational research. Students should have knowledge in multivariable modeling approaches. A course project will involve the application of propensity scores to a data set.
Course Activities: Lectures, readings, homeworks, computer labs, participation, project.
Course Notes: BIO210 or equivalent or EPI204 or equivalent required; instructor's signature required. Course meeting dates: TBA

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI284 Epidemiology of Neurologic Diseases
Spring 1
Dr. A. Ascherio, Dr. M. Weisskopf, Dr. M. Breteler

2.5 credits
Course offered 2008-2009; offered alternate years.
Lectures, seminars. Two 2-hour sessions each week.

This course is designed to introduce students to the epidemiology of major neurologic diseases. The emphasis will be both on research methods and on substantive issues. The course will stress etiologic and research intergrating epidemiology with clinical and pathological aspects. Neurological diseases that will be discussed include multiple sclerosis, cerebrovascular diseases, Alzheimer's disease, dementia, Parkinson's disease, amyotrophic lateral sclorosis, cancers of the nervous system and epilepsy.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI286 Advanced Pharmacoepidemiology
Spring 2
Dr. S. Schneeweiss

2.5 credits
Seminars, lectures. Two 2-hour sessions each week.

Using current examples and with the participation of active researchers in pharmacoepidemiology, this course addresses a range of study designs and analytic techniques for observational studies on the utilization, safety, and effectiveness of pharmaceuticals. Students will develop an understanding of how to plan, implement, analyze, and criticize pharmacoepidemiologic studies. Original research will be presented by principal investigators, followed by intensive discussions on design options, analytic strategies, and sensitivity analyses of confounding and misclassification bias. Lectures will provide methodological background and will cover applied issues typically encountered in pharmacoepidemiology. This course is intended primarily for graduate students considering a career in the pharmaceutical/biotech industry, pharmaceutical benefits management, or in national regulatory bodies.
Course activities: Class discussion, reading homework, individual class presentations.
Course notes: EPI 203, EPI 204, EPI 221, and BIO 210 or BIO 223, or signature of instructor required; familiarity with logistic regression and survival analysis is expected.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI288 Data Mining and Prediction
WinterSession
Dr. N. Cook, Dr. E.F. Cook

2.50 credits
Lecture, computer lab. Eight 3-hour lectures and with daily 2-hour computer labs over two weeks.

This course will present an introduction to the methods of data mining and predictive modeling, with applications to both genetic and clinical data. Basic concepts and philosophy of supervised and unsupervised data mining as well as appropriate applications will be discussed. Topics covered will include multiple comparisons adjustment, cluster analysis, self-organizing maps, principal component analysis, and predictive model building through logistic regression, classification and regression trees (CART), multivariate adaptive splines (MARS), neural networks, random forests, and bagging and boosting.
Course Activities: Computer labs.
Course Note: Students should be familiar with logistic regression (EPI236, BIO213, BIO210, or equivalent); signature of instructor required; no auditors.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI289 Models for Causal Inference
Spring 1
M. Hernán

2.5 credits
Lectures, labs. Two 2-hour sessions each week, one 2-hour lab each week.

EPI289 describes models for causal inference, their assumptions, and their practical application to epidemiologic data. The course introduces ropensity score methods, the parametric g-formula, inverse probability weighting of marginal structural models, g-estimation of nested structural models, and instrumental variable methods. The course also introduces methods for causal inference in the presence of time-varying exposures, and for infectious disease epidemiology, which will be extensively studied in EPI207 and EPI260/EPI501, respectively. EPI289 is designed to be taken after EPI201/EPI202 and concurrently with EPI204. The epidemiologic concepts and methods studied in EPI201/202 will be reformulated within a modeling framework in EPI289, and the statistical models described in EPI204 will be used throughout EPI289. Some familiarity with the SAS anguage is recommended.

Course Note: Wednesday lab required; no auditors.
Course Evaluations


EPI291 Data Collection
WinterSession
M. Murray

2.50 credits
Course not offered 2006-2007
Seminar. Two 1-hour sessions, two 4-hour labs

This is a practical data collection experience that involves surveying and measurements to be performed in the Brigham and Women's Emergency Room. Course participants will be expected to recruit and collect data directly from study participants for two 4-hour shifts per week, scheduled in the afternoons or evenings. The course will also meet for hourly classes twice a week; these classes will include lectures and discussions on practical aspects of study design and data gathering and management including recruitment, dealing with IRBs, writing surveys and consents, setting up data systems and troubleshooting. This course will fulfill the Epidemiology doctoral student's requirement to participate in data collection.
Course note: Pass/Fail option only. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI293 Analysis of Genetic Association Studies Using Unrelated Subjects
WinterSession
Dr. P. Kraft

2.50 credits
Lectures, case studies. Eight 3-hour sessions and three computer labs during WinterSession.

This course introduces the conceptual and practical tools needed for genetic association studies using unrelated subjects. Students will gain hands-on experience with a range of analytic tools and software packages as part of a class project which gives them the opportunity to design and analyze an association study. This project will require students to tackle real-world problems such as marker selection, potential multiple comparisons issues due to multiple markers and multiple outcomes, and missing data. Lectures and selected readings present key ideas (such as linkage disequilibrium, "tagging SNPs," haplotypes, population stratification and epistasis) and appropriate statistical methods.
Course note: BIO201, EPI201 and at least one of BIO210, BIO213 or EPI204, or signature of instructor required. Familiarity with SAS or S-PLUS/R and UNIX computing environment also highly recommended. (5.06)


Course Evaluations


EPI294 Screening
Spring 2
Dr. S. Hernandez-Diaz

2.5 credits
Lectures. Two 2-hour sessions each week.

The aim of this course is to provide an understanding of the principles of screening across a spectrum of diseases. Particular emphasis is placed on the methodological issues fundamental to the design and evaluation of screening programs. The first part of the course will address the study designs and measures used to evaluate screening tests and screening programs. Then we will discuss current approaches to screening for specific diseases, which highlight various themes in screening as well as discuss future directions in the development of new screening tests. We will explore screening for cancer cardiovascular disease, infectious diseases, childhood and prenatal screening, both in the United States and globally. The strengths, controversies and limitations of screening strategies will be discussed.
Course Activities: Active class participation, one problem set, debate of a current screening topic, a final 5-page paper.
Course Notes: One of EPI200, EPI201, EPI208 or signature of instructor required.

Course Evaluations


EPI295 Pharmacoepidemiology: Introduction
Summer 2
Dr. K. A. Chan

2.5 Credits
Lectures, small group discussions. Five 2-hour sessions each week.

This is an introductory course on pharmacoepidemiology. How the principles of modern epidemiology methods are used to evaluate the safety, effectiveness, and utilization patterns of drugs, vaccines, and medical devices will be discussed. Examples of descriptive epidemiology studies, cohort studies, case control studies, and intervention studies will be drawn from recent literature to illustrate the application of relevant methods and the challenges in drug safety assessment. Drug safety assessment from the pharmaceutical and biotechnology industry perspective and the regulatory perspective will be discussed. Practical issues such as data sources, ethical principles and advanced methodologic topics, such as confounding by indication and misclassification and the analytic methods to address them will be briefly introduced.
Course Activities: Written and oral group projects, individual class presentations, class discussion.
Course Note: EPI200 or EPI208 or permission of instructor required. Recommended for students interested in a general overview of pharmacoepidemiology. Credits cannot be given for students who have taken EPI221 (or vice versa.) A minimum enrollment of 8 students is required for course to be offered.

Course Evaluations


EPI296 Bridging Psychiatric Morbidity & Reproductive Outcomes
WinterSession
Dr. B. Harlow

1.25 credits
Seminar. Five 3-hour sessions for one week.

This course will include didactic lectures followed by a seminar format to assess the current knowledge regarding the relationship between psychiatric morbidity (i.e. mood disorder, anxiety, schizophrenia, etc.) and adverse reproductive events (i.e. pregnancy complications, infertility, menstruation, menopause). Students will be expected to critically evaluate existing literature in one of the above content areas, and present the findings, lead a discussion regarding methodological limitations and the interpretation of data, and put forward recommendations regarding future research initiatives that would enhance our understanding regarding the specific psychiatric and reproductive association.

Course note: Enrollment Minimun of 7. Enrollment Max of 15.

Course Evaluations


EPI298 Case-based Seminars on Drug Safety
Spring 1
Dr. S. Hernandez-Diaz, Dr. S. Setoguchi

2.5 Credits
Not Offered 2009-2010
Case Studies. Two 2-hour lectures each week.

This course acquaints students with practical issues in pharmacoepidemiologic research. Through the critical review and thoughtful discussion of crucial drug safety debacles, the students will develop an understanding of which adverse drugs effect have shaped our discipline, how were they discovered, with what delay, which were the specific methodological challenges, what were the political implications and, most importantly, which lessons have we learnt. Students are graded on the basis of participation in class discussion and preparation of a group project. This course is intended for students whose career might involve the development, prescription, marketing, evaluation or regulation of drugs.
Course Evaluations


EPI300 Independent Study/ Tutorial
Fall 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required. (5.06)

Course Evaluations


EPI300 Independent Study/ Tutorial
Fall
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required. (5.06)

Course Evaluations


EPI300 Independent Study/ Tutorial
Fall 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required. (5.06)

Course Evaluations


EPI300 Independent Study/ Tutorial
Spring 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required. (5.06)

Course Evaluations


EPI300 Independent Study/ Tutorial
Spring
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required. (5.06)

Course Evaluations


EPI300 Independent Study/ Tutorial
Spring 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required. (5.06)

Course Evaluations


EPI300 Independent Study/ Tutorial
WinterSession
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required. (5.06)

Course Evaluations


EPI300 Independent Study/Tutorial
Summer
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


EPI311 Teaching Assistant
Fall 1
Department Members

Time and credit to be arranged.

Course Evaluations


EPI311 Teaching Assistant
Fall
Department Members

Time and credit to be arranged.

Course Evaluations


EPI311 Teaching Assistant
Fall 2
Department Members

Time and credit to be arranged.

Course Evaluations


EPI311 Teaching Assistant
Spring 1
Department Members

Time and credit to be arranged.

Course Evaluations


EPI311 Teaching Assistant
Spring
Department Members

Time and credit to be arranged.

Course Evaluations


EPI311 Teaching Assistant
Spring 2
Department Members

Time and credit to be arranged.

Course Evaluations


EPI311 Teaching Assistant
WinterSession
Department Members

Time and credit to be arranged.

Course Evaluations


EPI315 Research: Clinical Epi
WinterSession
Dr. E.F. Cook

Time and credit to be arranged.

All students working in the Concentration of Clinical Epidemiology, who intend to complete the requirements for a Master of Science in Epidemiology based on only a summer schedule, are required to undertake and complete a clinical research project at their institution. Five to 12.5 tutorial credits will be granted for this research. Each student is required to submit a written paper summarizing his or her research project. The exact content of this research project is determined by the faculty member assigned as principal advisor to the student. An appropriate content for this project might include the development of a research proposal to address a clinical question of interest, the implementation of this proposal with the collection of patient data, the analysis of these data, and the creation of a publishable manuscript (with detailed appendices) to describe the results of the analysis. Alternatively, part of this project might pertain to the creation of a full-fledged RO1 study protocol in the National Institutes of Health format, a publishable paper based on the analysis of existing data, a decision analysis, or a cost-effectiveness analysis.
Course Activities: Supervised research. Written progress reports must be submitted each semester.
Course Note: Acceptance into the Program in Clinical Effectiveness and completion is required; pass/fail grading option only.



Course Evaluations


EPI315 Research: Clinical Epi
Spring
Dr. E.F. Cook

Time and credit to be arranged.

All students working in the Concentration of Clinical Epidemiology, who intend to complete the requirements for a Master of Science in Epidemiology based on only a summer schedule, are required to undertake and complete a clinical research project at their institution. Five to 12.5 tutorial credits will be granted for this research. Each student is required to submit a written paper summarizing his or her research project. The exact content of this research project is determined by the faculty member assigned as principal advisor to the student. An appropriate content for this project might include the development of a research proposal to address a clinical question of interest, the implementation of this proposal with the collection of patient data, the analysis of these data, and the creation of a publishable manuscript (with detailed appendices) to describe the results of the analysis. Alternatively, part of this project might pertain to the creation of a full-fledged RO1 study protocol in the National Institutes of Health format, a publishable paper based on the analysis of existing data, a decision analysis, or a cost-effectiveness analysis.
Course Activities: Supervised research. Written progress reports must be submitted each semester.
Course Note: Acceptance into the Program in Clinical Effectiveness and completion is required; pass/fail grading option only.



Course Evaluations


EPI315 Research: Clinical Epi
Summer
Dr. E.F. Cook

Time and credit to be arranged.

All students who intend to complete the requirements for a Master of Science in Epidemiology based on only a summer schedule, are required to undertake and complete a clinical research project at their institution under the supervision of a local mentor and a member of the Harvard faculty. Five to 12.5 tutorial credits will be granted for this research. Each student is required to submit a written paper summarizing his or her research project. The exact content of this research project is determined by the faculty member assigned as principal advisor to the student. An appropriate content for this project might include the development of a research proposal to address a clinical question of interest, the implementation of this proposal with the collection of patient data, the analysis of these data, and the creation of a publishable manuscript (with detailed appendices) to describe the results of the analysis. Alternatively, part of this project might pertain to the creation of a full-fledged RO1 study protocol in the National Institutes of Health format, a publishable paper based on the analysis of existing data, a decision analysis, or a cost-effectiveness analysis.
Course Activities: Supervised research. Written progress reports must be submitted each semester.
Course Note: Pass/fail grading option only.



Course Evaluations


EPI350 Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


EPI350 Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required. (5.06)

Course Evaluations


EPI350 Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required. (5.06)

Course Evaluations


EPI350 Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required. (5.06)

Course Evaluations


EPI350 Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required. (5.06)

Course Evaluations


EPI350 Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required. (5.06)

Course Evaluations


EPI350 Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required. (5.06)

Course Evaluations


EPI350 Research
Summer
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


EPI400 Non-Resident Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


EPI400 Non-Resident Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


EPI400 Non-Resident Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


EPI400 Non-Resident Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


EPI400 Non-Resident Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


EPI400 Non-Resident Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


EPI400 Non-Resident Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


EPI500 Fundamentals of Epidemiology
Summer 1
Dr. A. Hofman

2.5 credits
Summer 1
Lectures, seminars. Five 2-hour sessions each week.

This course will provide an orientation to epidemiology as a basic science for public health and clinical medicine. It will address the principles of the quantitative approach to clinical and public health problems. The course will discuss measure of frequency and association, introduce the design and validity of epidemiologic research, and give an overview of data analysis. This course is an introduction to the skills needed by public health professionals and clinicians to interpret critically the epidemiologic literature. It will provide students with the principles and practical experience needed to initiate the development of these skills. Lectures are complemented by seminars devoted to case studies, exercises, or critique of current examples of epidemiologic studies.

Course Note: No Auditors
Course Evaluations


EPI501 Dynamics of Infectious Diseases
Spring 2
Dr. M. Murray, Dr. T. Cohen

2.5 Credits
Lectures. Two 2-hour class sessions each week.

This course covers the basic concepts of infectious disease dynamics within human populations. Focus will be on transmission of infectious agents and the effect of biological, ecological, social, political, economic forces on the spread of infections. We will emphasize the impact of vaccination programs and other interventions. The dynamics of host-parasite interaction are illustrated using basic mathematical modeling techniques.

Course activities: Written homework assignments and final exam. Previous coursework in epidemiology helpful.
Course Evaluations


EPI502 Biology and Epidemiology of Antibiotic Resistance
WinterSession
Dr. M. Lipsitch and Dr. G. Regev-Yochay

1.25 Credits
Lectures, Seminars. Three 2-hour sessions each week.

This course will cover concepts and issues in bacterial antibiotic resistance relevant to epidemiologic research in this field. The student will obtain understanding of the significance of the problem, the biology and mechanism of antibiotic resistance, risk factors for spread and measures to prevent this emerging problem. We will specifically assess different research designs and strategies used to measure the magnitude, risk factors and prevention measures, and their interpretations.

Course Note: EPI201 and BIO201 required or signature of the instructor.


Course Evaluations


EPI504 Epi of Disorders and Diseases of Childhood and Young Adulthood
Spring 1
Dr. A. Field

2.5 Credits
Course offered 2008-2009; offered alternate years.
Lectures, seminars, case studies. Two 2-hour sessions each week.

This course reviews current evidence on the burden, causes, and consequences of the major disorders, diseases, and injuries during childhood, adolescence, and young adulthood. Topics include autism spectrum disorders, attention deficit hyperactivity disorder, asthma, allergies, trauma, orthopedic injuries and condition, depression, anxiety, eating disorders, obesity, sexually, transmitted infections, reproductive disorders, and early life determinations of adult disease. The course also reviews the impact of cognitive and physical development on epidemiologic methods and provides students with skills to critically analyze studies in pediatric epidemiology.

Course Note: EPI200, EPI201, or EPI208 required.

Course Evaluations


EPI505 Epidemiologic Methods for Global Health:
Summer 1
Burden, Causes, Implementation, and

Dr. J. Ware, Dr. M.C. Smith Fawzi, Dr. E.F. Cook
2.5 credits
Lectures. Case Studies. Five 2-hour sessions each week.

The course will cover introductory level epidemiology and a biostatistics primer introducing basic principles of statistics, with a specific focus on problems related to global health. Students who take this course will fulfill the introductory level course requirement in epidemiology; however, it will not fulfill a course requirement for biostatistics. A key difference in this course compared with other introductory level courses in epidemiology is that it offers examples from global health to illustrate epidemiologic methods and describe statistical approaches used. At the conclusion of the course, students will have gained an understanding of how to apply basic epidemiologic methods to evaluate global health programs and to critically analyze literature focused on global health problems for the purpose of advancing program design and service provision that is evidence-based.
Course Evaluations


EPI506 Translational Reseach Methods
WinterSession
Dr. P. Muti

1.25 Credits
Lectures. 2 two-session each week.

The course will explain translational studies and their scientific meaning in cancer models, by critically analyzing translational studies in oncology. Through class participation and discussion, students will learn methods used to collect and analyze data, synthesize data from translational studies, within cancer topics and be able to concisely present this information both orally and written. Topics such as the definition of translational studies, clinical setting, study designs, patient stratification, study limitations and pitfalls, the epidemiological view and the P53 model will be covered. Students will be given homework assignments and will be asked to work in small groups on the development and application of a translational study, which will include a class presentation. No previous experience is required to attend the course.
Course Evaluations


EPI507 Genetic Epidemiology
Fall 2
Dr. D. Hunter, Dr. J. Han

2.5 credits
Lectures. One 2-hour lecture each week.

Introduces the basic principles and methods of genetic epidemiology. After a brief review of the history of genetic epidemiology, methods for the study of both high penetrance and low penetrance alleles will be described and discussed. Methods of analysis of genome-wide association studies are a particular focus. Examples of the contribution of genetic analysis to major diseases will be reviewed.

Course Actives: Lectures, final examination

Course Note: EPI249 or equivalent required.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


EPI509 Evidence Based Epidemiology
WinterSession
Dr. J. Ioannidis, Dr. P. Boffetta

2.5 Credits
Running all day for 5 consecutive days in January

The course will have sessions in three formats: lectures, interactive presentations and discussion of examples, and building research-ideas.
A. The following topics will be covered in 5 circles of lectures:
1. Introduction to evidence-based epidemiology
2. Significance and credibility
3. Biases and errors
4. Integration of similar types of evidence (meta-analyses and individual-level analyses)
5. Integration of different types of evidence (epidemiology and biology)
6. Principles for collaborative research and collaborative structures (multi-center studies, networks, consortia)
7. Translation: principles, efficiency and pitfalls
8. Personalized medicine: expectations and pitfalls
B. There will be a series of short presentations where students will present/discuss with guidance from the tutors specific examples from recent cutting-edge applications of epidemiology, with emphasis on molecular/ translations applications, large-scale evidence, and collaborative efforts.
C. Brainstorming sessions for ideas for empirical research projects emerging during the lecturers and shorter presentation. Participants are encourages to take the lead in at least one project and probe its initial feasibility. Feasible projects may then continue after the course by interested students.

Course Evaluations


EPI510 Global Cancer Epidemiology
WinterSession
Dr. P. Boffetta

1.25 Credits
Lectures. Five 4-hour sessions each week.

This course provides student an introduction to the global epidemiology of cancer as a tool to understand the worldwide pattern of cancer, the main risk factors operating in different regions, and the main approaches for cancer prevention and control. Emphasis is given to cancer in low- and medium-resource countries, including cancers of the liver, esophagus, cervix, and stomach. The course will address epidemiological research conducted in low- and medium-resource countries and strategies for cancer prevention, screening and downstaging. Students will be required to develop a concept of an original research project.

Course Note: Pass/Fail grading option only. Class Max of 20. Instructor's signature required.
Course Evaluations


GCD211 Metabolic Processes Underlying Complex Diseases
Fall
Dr. B Manning, Dr. C. H. Lee

5 Credits
Lectures. Two 2-hour sessions each week.

This course will cover mechanisms controlling key cellular and organism metabolic processes and how deregulation of these processes contribute to complex human diseases, such as cancer and metabolic diseases. Part 1 will focus on cellular metabolic pathways and signaling networks underlying tumorigenesis. Party 2 will emphasize organismal metabolism, inter-tissue communication and the pathophysiology of diabetes, dyslipdemia and atherosclerosis. The course will meet twice a week, with one day of lecure and the other dedicated to critical reading and discussion of classic and current primary literature. This course is limited to 15 students from the Harvard Integrated Life Sciences (HILS) doctoral programs, or other graduate programs with permission from instructors. A firm knowledge of basic biochemistry is a prerequisite.

Course Note: Ordinal grading option only.
Course Evaluations


GCD300 Independent Study/Tutorial
Fall 1
Department Members

Time and credit to be arranged

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required.
Course Evaluations


GCD300 Independent Study/Tutorial
Fall
Department Members

Time and credit to be arranged

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required.
Course Evaluations


GCD300 Independent Study/Tutorial
Fall 2
Department Members

Time and credit to be arranged

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required.
Course Evaluations


GCD300 Independent Study/Tutorial
Spring 1
Department Members

Time and credit to be arranged

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required.
Course Evaluations


GCD300 Independent Study/Tutorial
Spring
Department Members

Time and credit to be arranged

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required.
Course Evaluations


GCD300 Independent Study/Tutorial
Spring 2
Department Members

Time and credit to be arranged

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required.
Course Evaluations


GCD300 Independent Study/Tutorial
WinterSession
Department Members

Time and credit to be arranged

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required.
Course Evaluations


GCD350 Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


GCD350 Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


GCD350 Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


GCD350 Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


GCD350 Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


GCD350 Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


GCD350 Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


GCD400 Non-Resident Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GCD400 Non-Resident Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GCD400 Non-Resident Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GCD400 Non-Resident Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GCD400 Non-Resident Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GCD400 Non-Resident Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GCD400 Non-Resident Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GCD400 Non-Resident Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP211 Management Control in Health Organizations
Fall 2
Dr. M. Mitchell

2.5 credits
Lectures, case studies. Two 2-hour sessions each week.

This course is designed for students interested in learning about finance and management of health care in low and middle income countries. The focus will be on the development of knowledge and skills that are needed by managers of health care organizations in a variety of settings. It will cover a broad range of topics including cost analysis, budgeting and control, financial analysis, revenue generation, and performance monitoring. While some theory will be presented, this course will emphasize practical applications of the techniques discussed through the use of the case study method. Although no prior education in financial or managerial accounting is required to take this course, students without any prior training will be expected to do extra work to learn the basics of financial accounting.
Course Note: Students who have or are taking HPM219 or HPM220 may not take this course for credit.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP214 Health, Human Rights, and the International System
Fall 2
Dr. S. Marks

2.5 credits
Lectures, seminars. One 3-hour session each week.

This course is designed to provide an overview of the way international institutions deal with health and human rights issues. Focus will be on the responses of the United Nations system, including the World Health Organization (WHO), regional organizations, and non-state actors to some of the pressing issues of health from a human rights perspective. Issues to be explored include: mother-to-child transmission of HIV and ARV drug pricing in Africa; traditional practices, such as female genital cutting (FGC); forced sterilization and rights of indigenous people in Latin America; accountability for mass violations of human rights; health of child workers; and international tobacco control. Among the international institutions to be examined are the WHO, UNAIDS, the World Trade Organization (WTO), UNESCO, the Council of Europe, the Organization of American States, the World Bank, and the International Criminal Court (ICC). The principal teaching method is simulation of actual cases, in which students prepare and present positions of various protagonists, based on research into those positions. The ultimate aim of the course is to prepare students to work for and interact professionally with international institutions to advance the health and human rights objectives, whether through governmental, intergovernmental or nongovernmental processes. (5.06)



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP218 Health and Human Rights: Concepts and Methods for Public Health
Fall 1
Dr. S. Gruskin

2.5 credits
Lecture, case study. One 3-hour session each week.

The course identifies and discusses the complex interactions between health and human rights, with particular emphasis on the use of human rights concepts and methods for public health practice. The course provides basic literacy in modern human rights. Frameworks for analysis of health/human rights interactions are developed and applied, including: effects of health policies and programs on human rights; health consequences of human rights violations; and the linkages between promoting and protecting health and promoting and protecting human rights. Topics including reproductive health and HIV/AIDS are used to illustrate and explore practical applications of human rights in public health, including the value and effectiveness of what are called "rights-based" approaches to health.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.

Course Evaluations


GHP220 Introduction to Demographic Methods
Fall 2
Dr. M. Castro

2.5 Credits
Lectures, class discussions, labs.

This is an introductory level class on the analysis of mortality, fertility and population change. It is required for all masters' and doctoral students in the department of Global Health and Population. Students are introduced to the core literature in this field through lectures, and assigned readings selected from peer-reviewed journals and textbooks. Together, these provide a graduate-level introduction to the principle sources and characteristics of population data and to the essential methods used for the analysis of population problems. The emphasis throughout is on understanding the key processes, models and assumptions used primarily for the analysis of demographic components. Practical training will be given through a required weekly laboratory session, assignments, and a final examination. Examples presented in class and used in assignments are drawn from several countries, combining both developed and developing in assignments are drawn from several countries, combining both developed and developing world realities.

Course Note: Ordinal grading option only.

Course Evaluations


GHP244 Health Sector Reform: A Worldwide Perspective
Fall 2
Dr. T. Bossert

2.5 credits
Lectures. Two 2-hour sessions each week.

This course surveys the impact of the global movement to reform national health care systems in the lower and middle income countries. It introduces a framework for analyzing health care systems and designing strategies for system reform, including political dimensions, with specific references to developing countries. It then examines some of the major elements of reform strategies as they are being applied in these countries, including goal-setting, financing, the organization of health care and the role of the private health sector, governmental reform, regulation, and change in consumer behavior. Studies and case material from many different countries are used.



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP251 Planning and Evaluation of Health Programs
Spring 2
Dr. M. Mitchell

2.5 credits
Lectures, case studies. Two 2-hour sessions each week.

This course is an introduction to monitoring and evaluating both U.S. and international health programs and interventions. It aims to combine a solid theoretical understanding of the principles of evaluation with illustrations of practical application. The course will rely heavily on the use of case materials to illustrate how evaluations are done in the field.

The course will provide an overview of the reasons for undertaking a health evaluation and will consider appropriate conceptual frameworks for evaluation. A variety of methods for obtaining information are presented including the use of qualitative and quantitative data and how each of these might be collected in a variety of settings. Students are introduced to practical problems encountered in designing and conducting evaluation studies in a variety of settings including disease specific control programs, primary health care, training and communications programs and reproductive health.
Course Note: The course is intended for MPH and MS and doctoral students interested in health program evaluation. (5.06)



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP253 Human Ecology
Fall 2
Dr. R. Levins

2.5 credits
Lectures. Two 2-hour sessions each week.

Provides a broad overview of the human ecosystem as it emerges out of, but as different from, pre-human ecology. Topics are selected from biosphere processes, population interaction, agricultural systems, adaptation evolution and ecology of disease, ecological politics, and evolution. Also considers the role of knowledge and conscious planning as an aspect of human ecology and examines the approaches toward the solution of ecological problems.

Course Note: Basic knowledge of biology recommended.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP261 Models of Complex Systems in Biology and Public Health
Spring
Dr. T. Awerbuch(P), Dr. R. Levins (S)

2.5 credits
Lectures. One 2-hour session each week.

This course examines complex models as a basis for analyzing biological and social phenomena relevant to public health. Applied topics include: spread and maintenance of infectious diseases such as AIDS, lyme disease and malaria; diffusion bioassays for determining toxicity and mutagenicity of drugs; screening for breast cancer; blood screening, enzyme kinetics; demographic modeling and population structures. Methodological topics include differential equations, difference equations, probability, Leslie matrices, fitting models to data and computer simulation.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP263 Grant Writing for Funding of Research and Health Care Projects
WinterSession
Dr. K. Dumbaugh (P), Dr. D. Bloom (S)

2.5 credits
Lectures, seminars. Ten 3-hour sessions from Monday, January 4, 2010 - Friday, January 15, 2010 from 9:00-12:00 AM with an additional 2.5 hour session on Wednesday, January 6 from 6:00-8:30 PM. A mandatory organizational meeting to discuss concept paper requirements and the course objectives will be held on Thursday, November 12, 2009, from 12:30 to 1:20 PM, Room TBA.

The objective of the course is to provide participants with: 1) the opportunity to prepare a fundable grant proposal for submission to a funding agency upon completion of the course; 2) a framework that enables participants to write realistic and fundable proposals for basic or applied research, or for projects that deliver services or care. (Participants are required to obtain support from a mentor for their proposal before, during, and after the course); and 3) the most relevant sources of information about organizations that fund such work.

Course Note: Enrollment is limited to 18 students. Signature of instructor required. Submission of concept paper requirement will be discussed at a mandatory organizational meeting on Thursday, November 12, 2009, from 12:30 to 1:20 p.m. By Wednesday, December 2, interested students must submit a 200 word (two short paragraphs) description of their idea for a proposal for review to kdumbaug@hsph.harvard.edu with phone number where the student can be reached for discussion of proposed project idea. Selection of participants will be based on the order in which students submit and review their concept paper with the instructor. Selection will start by Thursday, December 4, 2009.

Course grading: 30 % class discussion, 20 % class presentation, 50% draft proposal.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP265 Ethical Issues in Global Health Research
Spring 2
Dr. R. Cash, Dr. D. Wikler

2.5 credits
Course Not Offered 2009-2010
Seminar. One 3-hour session each week.

This course is designed to expose students to the key ethical issues that may be encountered in the course of conducting global health research. Using case presentations and discussion-based class sessions, students will have the opportunity to begin developing their own tools for dealing with these important issues in an applied context. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP267 HIV/AIDS in Developing Countries: Epidemiol & National Responses
Fall 2
Dr. D. Halperin

2.5 credits
Lectures, case studies. Two 2-hour sessions each week.

This course is designed to provide a broad description of the distinct features of the HIV/AIDS epidemic in developing countries, and the evolution of national responses against HIV/AIDS in selected countries. The course will focus on sub-Saharan Africa, although relevant examples from other developing countries will be addressed during the presentations and discussions. At the beginning of the course, an overview of the status of the HIV/AIDS epidemic will be presented and followed by a discussion of the methods used to derive regional HIV/AIDS estimates. Later, specific factors contributing to the severe HIV/AIDS epidemic in sub-Saharan Africa will be examined, and strategies that could be used to reduce further spread of the epidemic will be discussed. Subsequent sessions will focus on the evolution of national responses against HIV/AIDS epidemic in selected countries. In each country, the main features of the national HIV/AIDS control program will be described, and the key strategies adopted in reducing further spread of the HIV epidemic will be presented and critiqued.

Course Activities: Case studies from selected countries where HIV/AIDS interventions have worked (or not) will be presented and discussed to assess the possibility of replicating programs from countries where HIV/AIDS interventions have been more or less successful. A combination of formal lectures, case studies and student presentations will be used.

Course Note: No auditors; enrollment limited to 35.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP268 Field Experience in Health and Human Rights
WinterSession
Dr. S. Marks

1.25 credits
Seminars, field work

In this course, students will acquire the basic skills in applying a human rights framework to health issues in a professional work environment. Depending on their field placement, they may learn about operational skills in settings where health and human rights are practiced or about organizing a study to investigate human rights conditions affecting health. Each student will be expected to identify an organization with which they would like to work for the Winter Session period and secure a placement within that organization. Students are expected to attend a short preparatory workshop in the Fall 2 quarter. Participants will study materials pertinent to their placement and project before heading to the field assignment. After completion of their field work, each student is required to hand in a 10-page paper to be graded by the course instructor on a pass/fail basis.
Course Note: Enrollment limited to 15; contract with department required; attend a short workshop in Fall 2; pass/fail option only. Applications must be completed by October 8 and participants will be notified by October 19.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP269 Applied Politics and Economics I: Political Economy of Intl Hlth
Spring 1
Dr. M. Reich

2.5 credits
Lectures, seminars, case studies. Two 2-hour sessions each week.

Presents theoretical perspectives, empirical cases and research issues in policy analysis, political economy, political strategies and governance in international health. Focus is on analytical and methodological issues as applied to international health policy. Examines the political economy constraints on national and international health initiatives, the role of international agencies, the impact of non-governmental organizations, and the role of the state.
Course Activities: All students will be expected to participate actively in class discussions. There will be a midterm and a final paper due at the end of the course. Doctoral students will be expected to prepare a more extensive final paper. Exams and papers will constitute 70% of the grade and class participation 30%. (5.06)



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP272 Foundations of Global Health and Population
Fall
D. Bloom, J. Lamstein

5.0 credits
Lectures, seminars. Two 2-hour sessions and one 2-hour lab each week.

This course is required for all incoming master of science and doctoral students. It is intended as a broad survey of the main facts, issues, perspectives, methods, results, and conclusions in the areas of global population and health.

The course is organized into three blocks. The first block deals with theory, methods, and evidence related to the state of global health and population and reviews salient population and health issues, both past and present. The focus is on patterns and trends in morbidity, mortality, fertility, and reproductive health, as well as the size, structure, and growth of population. Environmental concerns linked to health and population are also addressed.

The second block deals with the economic, social, legal, political, and ecological context in which global health and population issues arise and must be addressed. This block introduces economic, political, and rights-based perspectives on the place of health in the process of international development.

The third block covers approaches to the design and implementation of policies and programs to address health and population problems. Medical interventions, non-medical health interventions, and non-health interventions will all be considered.

Course Note: Space guaranteed for all SM and doctoral students in the department of Global Health and Population; others on a first-come basis.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP274 Applied Quantitative Methods I
Fall 1
Dr. S. Humair

2.5 credits
Lectures. Two 2-hour sessions each week.

This course will review, as well as introduce, methods of mathematical analysis that form an essential tool kit for doctoral level courses in economic analysis. The course is a pre-requisite for GHP291 (Microeconomics and applications to public health in developing countries) that is taught in the spring semester. Topics covered include differential and integral calculus, and optimization methods. Some applications of these methods to economic analysis will also be discussed. Participants in the course will be expected to be proficient in introductory level calculus and linear algebra.
Course note: There will be weekly problem sets, a take-home mid-term examination and an in-class final examination. Lab or section time will be announced at first meeting.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP283 Pharmaceutical Policy and Global Health
Spring
Dr. Michael R. Reich

2.5 credits

Lectures, case studies: One two-hour session each week.

The course consists of readings and presentations on major issues related to pharmaceutical policy and global health, with particular attention to access to medicines. Topics will include: essential drugs, the global market for pharmaceuticals, patents, drug development, price policy, international trade agreements, drug development for neglected diseases, non-governmental organizations, generic drugs, vaccines, AIDS medicines, drug donation programs, and the politics of national drug policies.. Each session will consist of a brief presentation by a student, followed by general discussion. Some topics will be presented by visiting experts. Each student will be required to write a 15-20 page paper.

Course Note: Enrollment limited to 20, instructor's signature required. Interested students should submit a CV and short statement (300) words on why they want to take the course to michael_reich@harvard.edu. No auditors.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP288 Issues in Health and Human Rights
Spring 2
Dr. S. Marks

2.5 credits
Not Offered 2008-2009
Lectures, case studies. Two 2-hour sessions each week.

The aim of this course is to introduce students to the application of the human rights framework to a wide range of critical areas of public health. Through lectures, cases and guest speakers, students will become familiar with the human rights perspective as applied to selected public health policies, programs and interventions. The course clarifies how human rights approaches complement and differ from those of bioethics and public health ethics.

Among the issues to be considered from a human rights perspective are the bioethics and human rights as reflected in the Nuremberg code, torture prevention and treatment, infectious diseases: MDRTB and incarceration, violence prevention and responses, genetic manipulation, access to affordable drugs, community-based health management and financing, child labor, aging, and tobacco control.
Course requirements are active participation in class discussion (20%) and a term paper (80%)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP291 Microeconomics and Applications to PH in Developing Countries
Spring
Dr. A. Mahal

5.0 credits
Lectures. Two 2-hour sessions each week.

This is a course in applied microeconomic theory (formerly GHP271). We use basic calculus, differentiation, and simple constrained maximization theory to develop empirical models of the behavior of individuals, households, firms, and markets, as well as normative theories of social welfare and resource allocation within the health sector. All applications will be drawn from population and public health issues in developing countries. Empirical applications include individuals' demand for health care, health insurance, and retirement saving; the determinants of fertility and educational investments in children; the distribution of resources within households; formal and informal mechanisms for risk sharing; the supply of physician and health services; market failures and inefficiencies due to asymmetric information in health insurance markets; and applications of the theory externalities and public goods to disease control and environmental policy. Normative applications include the trade-off between equity and efficiency, criteria for resource allocation and project evaluation within the health sector such as cost-benefit and cost-effectiveness analysis, and ethical issues such as the valuation of life, the multiple competing objectives of health policy, and fairness.
Course note: The course makes use of calculus and constrained maximization at the level of GHP274 or equivalent. (7.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP293 Individual and Social Responsibility for Health
Fall 1
Dr. D. Wikler

2.5 credits
Course Not Offered 2009-2010
Lectures, case studies. Two 2-hour sessions each week.

The concept of responsibility for health plays a key role in health policy, but it is rarely articulated or evaluated. In this course, students will consider alternative understandings of assignments of responsibility for health to individuals, the state, the family, communities, nonprofit and for-profit firms, and other entities. They will identify their occurrences in health policy debates, assess the cogency of their use in ethical arguments in health policy, and trace the policy consequences of their normative analyses. The course will also serve as an introduction to ethical perspectives on public health.
Course Note: Minimum enrollment of 15 required. Evaluation of Performance: Exams and a term project identifying and evaluating the role of responsibility for health in an area health policy. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP294 International Health Economics I
Fall 1
Dr. R. Soares

2.5 credits
Lectures. Two 1.5-hour lectures each week.

The course is designed to use economic methods to study a range of issues in international health economics. It will examine the determinants and impact of the epidemiological and demographic transitions, the role of health as a form of human capital, and the impact of population changes and health improvements in economic development, each with an international focus. The topics in the course will be addressed from an economic perspective, with emphasis on historical examples, current facts, relevant economic theories and hypotheses, existing empirical research, gaps in the existing literature and prospects for future research in the area.
Course note: GHP291 or signature of instructor required.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP297 Field Trip: Health Reform and Community Medicine in Chile
WinterSession
Winter Session

Dr. T. Bossert
1.25 credits
Jan. 4 - Jan 22, 2010


This Winter Term course will allow students to see first hand two major current public health issues in a remarkable and exciting period of innovation in Chile: the process of reforming health systems and innovations in community medicine approaches, including the assessment of social capital initiatives.

Chile was one of the first countries on the continent to significantly reform its health system in the 1980s, introducing new programs of public and private social insurance schemes, promoting the growth of private sector providers and decentralizing their public health services. It has been a model for health reform in many other countries. Since the restoration of democracy in the 1990s, many in the health sector have been proposing new reforms to correct many of the problems that emerged in implementation of the initial reforms.

A leader in promoting community-oriented health systems, Chile is also a laboratory of innovations in outreach programs, community participation, 24 hour emergency service units, and special programs for the elderly and other specific risk groups. Recent innovations in community medicine have been implemented by the Catholic University in pilot programs around Santiago. Complementing these programs is a research project to assess the role of social capital (trust in others and participation in voluntary groups) in health care services and health status.

The three week 1.25 credit course involves:

· introductory lectures by HSPH faculty to orient students to the key issues of health reform and community medicine in Chile
· lectures by key participants in the health reform process - past and present
· interviews with current stakeholders and observers of the health reform process
· lectures and field visits to community medicine pilot clinics
· individual short research projects on health reform, community medicine and/or social capital

The course will be for 1.25 credits and will require a power point presentation on individual research into one of the topics of the course. The course dates are January 4 to 22 - a beautiful summer time period in Santiago. Housing arrangements can be made at a reasonable price in university housing. Collective flight arrangements may also be possible. Spanish will be helpful but not essential.

Course Note: Enrollment is limited to 15 students; pass/fail grading option only. An orientation session will be held to discuss the course options with interested students. Applications must be completed by October 8 and participants will be notified by October 19.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP298 Field Trip to Mumbai India
WinterSession
WinterSession

Dr. R. Cash
1.25 credits
January 4 - January 22, 2010

The purpose of the three-week visit is to familiarize the students with the health problems and health systems of India, especially the urban areas. The program would be based in Mumbai, the largest urban area in India and one of the world's largest. The students will be hosted by the Tata Institute for Social Sciences (TISS) in Mumbai (it has one of the few MPH programs in India,) which will direct the orientation program (including field trips) and set up the field placements for each student. Students in groups of 2-6 will be assigned to various institutions and programs that reflect their own interests.

Course Note: Students who are enrolled in the MPH, MS, or doctoral program will be eligible. Pass/Fail grade only. Applications must be completed by Thursday, October 8, 2009 and participants will be notified by October 19. Sessions in which the health, culture, political, and socio-economic factors in Mumbai will be reviewed and scheduled for Fall 2. The program will be limited to a maximum of twelve students.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.

Course Evaluations


GHP299 Masters Thesis
Spring
Dr. A. Hill

5 credits

Student must produce a written thesis in accordance with the thesis guidelines developed by the department.
Course Note: Signature of instructor required; ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP300 Independent Study/ Tutorial
Fall 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses. The program provides an opportunity to consider the design of studies, programs, or analysis of data.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required.
(5.06)
Course Evaluations


GHP300 Independent Study/ Tutorial
Fall
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses. The program provides an opportunity to consider the design of studies, programs, or analysis of data.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


GHP300 Independent Study/ Tutorial
Fall 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses. The program provides an opportunity to consider the design of studies, programs, or analysis of data.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


GHP300 Independent Study/ Tutorial
Spring 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses. The program provides an opportunity to consider the design of studies, programs, or analysis of data.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


GHP300 Independent Study/ Tutorial
Spring
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses. The program provides an opportunity to consider the design of studies, programs, or analysis of data.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


GHP300 Independent Study/ Tutorial
Spring 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses. The program provides an opportunity to consider the design of studies, programs, or analysis of data.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


GHP300 Independent Study/ Tutorial
WinterSession
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses. The program provides an opportunity to consider the design of studies, programs, or analysis of data.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


GHP350 Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.
(5.06)
Course Evaluations


GHP350 Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP350 Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP350 Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP350 Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP350 Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP350 Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP356 Research Methods in Population
Fall
Dr. G. Wyshak


For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.
(5.06)
Course Evaluations


GHP356 Research Methods in Population
Spring
Dr. G. Wyshak

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


GHP400 Non-Resident Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.
(5.06)
Course Evaluations


GHP400 Non-Resident Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP400 Non-Resident Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP400 Non-Resident Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP400 Non-Resident Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP400 Non-Resident Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP400 Non-Resident Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


GHP502 International Reproductive Health Issues:From theory to Practic
Spring 1
2.5 credits

Ms. K. Blanchard, Dr. David Bloom (S)
Seminars, case studies

Description
This seminar will offer students the opportunity to explore the development and implementation of reproductive health research projects and programmatic initiatives in international settings. Through the examination of weekly case studies, students will acquire a better understanding of the complexity of working in the field of reproductive health in the international context and an appreciation of the ways in which the perspectives and methods of various health and social science disciplines can be integrated in the development of effective health programs. Session topics will include family planning, emergency contraception, abortion, and HIV/AIDS. Presenters will draw on case studies from Latin America, Sub-Saharan Africa, and the Middle East, and will identify both technical and programmatic challenges as well as successful interventions.
Course Objectives: At the completion of the course, you will be able to
1) Understand the range of international reproductive health issues, with particular emphasis on policy, clinical and rights challenges.
2) Critically review research results on international reproductive health.
3) Link policy and advocacy efforts and identify research opportunities that can inform these discussions.
Course note: Instructor's signature required.
Course Evaluations


GHP503 The Determinants of Fertility and Mortality
Spring 2
Dr. Kenneth Hill

2.5 credits
Course Not Offered 2009-2010

The course, intended for students who have completed a basic course in demographic measures, will examine the record of fertility and mortality change through the course of human history and of differentials in fertility and mortality. These theories include the effects of modernization, economics, technology, social structure and other factors bearing on human behavior. The first block covers theories of fertility and how well they account for the empirical observations, while the second block will do the same for mortality. The emphasis of the course will be on examining the agreement between theory and actual outcomes.
Course Objectives: At the end of the course the student will be able to:
Describe the broad trends of human fertility and mortality through history
Distinguish between the major theories of fertility and mortality change
Assess the strengths and weaknesses of each theory in explaining observed patterns
Course Note: GHP 220 or instructor signature required. Ordinal grading option only. (1.07)

Course Evaluations


GHP504 Applied Qualitative Methods for International Health Research
Spring 1
Dr. Theresa S. Betancourt

2.5 credits
Lectures. One 3-hour session each wwek.

The aim of this course is to provide students with an introduction to qualitative methods for international health research. The module is designed to expose students to a wide range of topics including: developing research questions, sampling and site selection, frequently used qualitative methods (such as interviews, observations, focus groups), design of qualitative research protocols, as well as data management and analysis. Students will engage in a variety of active learning exercises (such as constructing and conducting a short informal interview) and will work in small groups on the preparation of a qualitative research project on a defined topic area of international or multicultural health. Class activities and discussions will aim at building a research community in the class, where students support each other’s development as researchers recognizing the complexity, benefits and limitations of conducting cross-cultural qualitative research.

Course prerequisite:
Prospective students wishing to enroll in GHP 504 must email an essay (maximum one page) to course TAs, Ben Capistrant (bcapistr@hsph.harvard.edu) and Sandy Zaeh (szaeh@hsph.harvard.edu) by December 15, 2008. All admitted students will be notified by January 9, 2009.

The essay should describe:
- Current departmental affiliation, degree program and remaining time to graduation
- Rationale for and interest in pursuing training in qualitative methods
- Upcoming plans to use qualitative methods in research
-Any prior training in or experience with using qualitative methods in field research (and lessons learned if relevant)
- Research topics and populations in which the student plans to use qualitative methods

Course Note: Enrollment limited to 30 students. Ordinal grading option only.

Course Evaluations


GHP505 Sex, Reproduction and Reproductive Health
Spring 2
Dr. A. Hill

2.5 credits
Lectures, case studies. Two 2-hour sessions each week.

This is a second level class which builds on the material covered in GHP 272 (Foundations of Global Population and Health) and GHP 220 (Introduction to Demographic Methods). Students are introduced to the core literature in this field through lectures, readings presented in a course packet, case studies and other sources. Together, these provide a graduate-level introduction to the concepts underlying reproductive health and to the essential methods used for the analysis of fertility and reproductive problems. The emphasis throughout is on understanding the key processes, models and assumptions used primarily for the analysis of fertility and reproductive health in developing countries. Several case studies, including major interventions to improve reproductive health, are presented in detail. Practical training will be given through homework exercises, a mid-term and a final examination. Examples are drawn mostly from the Indian sub-continent, Africa and the Middle East. Useful for MPH students interested in fertility and reproductive health in developing countries.

Course Notes: There are no formal prerequisites for this course but students are expected to have a working knowledge of Excel or an equivalent spreadsheet package for the analysis and graphical display of demographic data. No auditors.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP506 Measuring Population Health
Spring 1
Dr. J. Salomon

2.5 credits
Lectures, lab. Two 2-hour sessions and one 2-hour optional lab each week.

This course is designed to introduce students to the definition and measurement of population health. The primary objective is to provide an overview of the conceptual, methodological and empirical basis for quantifying levels of health in individuals and populations, including the construction of a range of different summary measures that combine information on mortality and non-fatal health outcomes. The course aims to give students an understanding of the technical basis for measurement in international work on population health; and to give students an appreciation of the uses and limitations of these methods in policy-making and priority-setting, particularly in developing countries. Practical training will be given through homework exercises and a final exam. Students are expected to have a working knowledge of Excel or an equivalent spreadsheet package. Other packages such as Stata will be introduced during the course for those with no previous experience. Required for MS and doctoral students in the department of Global Health and Population. Useful for MPH students interested in the construction, interpretation and application of health indicators
Course Note: GHP 220: Introduction to Demographic Methods or permission of instructor. Optional lab meets Fridays from 10:30 to 12:20 in LL6.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP507 Population Health Risk Factors
Spring 1
Dr. M. Ezzati

2.5 credits
Lectures. Two 2-hour sessions.

Detailed knowledge of the roles of diseases and injuries, and of their causes and risk factors, is essential evidence for health policies and for planning and evaluating health systems and intervention programs. A substantial body of work has focused on the quantification of mortality and more recently non-fatal health outcomes, as covered in GHP220 (Introduction to Demographic Methods) and GHP506 (Measuring Population Health). Data on disease or injury outcomes alone tend to focus on palliative or curative services. Reliable and comparable analyses of lifestyle, environmental, and nutritional risks to health, on the other hand, are needed for preventing disease and injury. This course is designed to guide students through the multitude of concepts, methods, and data needed to conduct systematic assessment of health risks at the population level, and their applications, for example, in evaluating public health policies and intervention options.

The course builds on the knowledge and skills acquired in introductory epidemiology courses. The methods learned in the course, in addition to their independent applications to public health problems and priority setting, serve as a basis for other courses in the School, including those on evaluating the impact of health interventions, priority-setting using combinations of burden of disease and economic analyses.

The first block of lectures focuses on the concepts of risk assessment and the basic methods and data needs used for population level risk assessment. The second part of the course introduces the concepts of multiple risk factors and their analytical as well as public health implications. The last part of the course introduces the students to time dimensions of risk factor exposure, avoidable disease burden, and forecasts of future trends in disease with and without changes in the risk factors. The second and third blocks form the core of a more advanced risk factor course (GHP509).

Course Note: BIO200 or BIO201 and EPI200 or EPI201, or permission of the instructor required; ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP509 Advanced Seminar on Population Health Risk Factors
Fall 2
Dr. Majid Ezzati

2.5 credits
Not offered 2009-2010.
Seminars. One 3-hour session each week.

Detailed descriptions of the magnitude and distribution of diseases and injuries, and their causes are important inputs to strategies for improving population health. Analyses of disease or injury outcomes alone, such as death or hospitalization, tend to focus on the need for palliative or curative services. Reliable and comparable analysis of risks to health, on the other hand, is needed for preventing disease and injury. This seminar is designed to provide the students with an advanced understanding of the concepts and analytics related to health risks, with emphasis on their population level effects. We will use scholarly publications as the basis for critical discussion and probing of the of course topics. The topics included in the course will center around two broad themes:

1. Multiple risk factors
a. Relative and absolute risk concepts; risk factor interaction
b. Mediated effects
c. Risk factor correlation; risk factor and disease correlation
d. Multiple correlated risk factors and health inequalities

2. Temporal dimensions of risk factor analysis
a. Hazard accumulation and risk reversibility
b. Risk factor trends and avoidable disease burden

This seminar builds on the introductory knowledge and skills acquired in GHP 507 (Population Health Risk Factors). Although the seminar is designed primarily in preparation for research on risk factors, it will also create a strong foundation for applications such as evaluating the impact of health interventions and priority-setting using combinations of burden of disease and economic analyses.

Approximately two-thirds of the seminars will focus only on critical discussion of specific topics with reference to specific scholarly publications. In the last part, time will be divided between further seminar discussion and student presentation of ongoing papers with reference to the seminar topics for a critical discussion by their peers. The paper is expected to fit a research framework and have a theoretical underpinning, by either providing a detailed research proposal related to the student's research interests or resulting in a paper of publishable quality.

Course Note: GHP507 or instructor's signature required.


Course Evaluations


GHP510 Humanitarian Protection in Conflict:Legal and Policy Challenges
Fall
Mr. C. Bruderlein, Dr. J. Leaning

2.5 credits
Lectures, seminars, case studies. One 2-hour session each week

The protection of civilians during armed conflict is a complex and bold endeavor, requiring a multidimensional response to address the various sources of vulnerabilities affecting populations, in a strategic manner. For each of these vulnerabilities, distinct tools and standards must often be mobilized to analyze the causes of conflicts and consequences on populations. In this context, humanitarian professionals must engage in multifaceted and complex approaches addressing the legal, political, social, medical, and public health aspects of crises, in addition to managing operations in often remote and hazardous environments. Each of these domains, in turn, may also become the subject of various interpretations and agendas by the belligerents, host countries, donors, international agencies, and non-governmental organizations, increasing the importance of the strategic thinking, dialogue, and negotiation skills of humanitarian practitioners.

This course will offer a multidisciplinary approach to the protection of civilians during armed conflict, with a primary emphasis on student engagement. Through a careful blend of theory and practical application, this course seeks to acquaint students with the relevant legal, historical, and policy material and equip them with the necessary understanding and skills to address humanitarian concerns in an operational environment. It will provide students with an overview of the humanitarian framework related to the protection of civilians during armed conflicts, as well as encourage participants to explore and assess dilemmas of IHL and humanitarian action.

The main objective of the seminar is to prepare students to engage in a strategic reflection on the most pressing challenges confronted by governments, international organizations, and non-governmental organizations involved in areas of conflict.

Course Note: Students interested in the WinterSession course GHP 543 (Indonesia in 2010) are strongly advised to take this course.

Course Evaluations


GHP515 Humanitarian Studies in the Field
WinterSession
WinterSession

Dr. J. Leaning
2.5 credits
Seminar, case studies. Five 6-hour sessions each week.

This course will offer a practical and in-depth analysis of the complex issues and skills needed to engage in humanitarian work in field settings. Through presentations offered by the faculty of the Humanitarian Studies Initiative and guest speakers who are experts in their topic areas, students will gain familiarity with the primary frameworks in the humanitarian field (human rights, livelihoods, Sphere standards, international humanitarian law) and will focus on practical issues that arise in the field, such as rapid public health assessments, field cluster sampling techniques, application of minimum standards for food security, and operational approaches to relations with the military in humanitarian settings. Topics will be presented in case studies and in structured participatory modes. A paper of 5 pages will be required at the completion of the course analyzing a current humanitarian crisis from the perspective of one of the main topics presented in the course. Additionally, these topics will provide the foundational knowledge and skills needed to perform successfully during a Spring-02 course which will involve a three-day intensive simulation of a humanitarian crisis, which is a required component of the HSI program.

At the completion of this WinterSession course, the students will be able to fulfill the following learning objectives:

-To design a rapid health assessment in the field including applying appropriate epidemiological methods to assess population needs in crisis situations;
-To design, conduct, and analyze field interviews with key stakeholders in a humanitarian crisis - a cross-section of the local affected population, brigands and local militia, international heads of agencies, local and regional governmental officials, members of the local and international press, and representatives of the United Nations agencies;
-To synthesize the complex social, political, economic, geographic, and public health parameters that define the dynamic of a given humanitarian crisis; and
-To analyze the historical frameworks that define current approaches to humanitarian response and to assess the relative utility of these frameworks in a particular situation.

Course Note: For more information about the HSI program, visit www.humanitarianstudies.org.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.



Course Evaluations


GHP516 Humanitarian Studies in the Field II
Spring 2
Dr. J. Leaning

2.5 credits
Seminar, case studies. One 3-hour Session each week.

Special Class Sessions:
Friday, April 17, 2 - 5 pm class held in Kresge 201
Friday - Sunday, April 24-26, 2009 classes will take place in Andover, MA
Wednesday, April 29, 2009, 5 - 8 pm class will be held at Tufts University

This course offers an in-depth analysis of the complex issues surrounding humanitarian response as well as practical skills needed to engage in humanitarian work in field settings. Course topics will be presented in case studies and in structured participatory modes. Students will utilize knowledge of the humanitarian field gained in the Winter Session course GHP 515 (human rights, livelihoods, Sphere standards, international humanitarian law) during a field simulation exercise. During the simulated humanitarian crisis, involving faculty members, role-players, and guest experts, students will focus on practical issues that arise in the field, such as rapid public health assessments, field cluster sampling techniques, application of minimum standards for food security, and operational approaches to relations with the military in humanitarian settings.

The three-day simulation exercise will take place in the Harold Parker State Forest in North Andover, MA from Friday morning through late Sunday afternoon at the end of April. Students will spend two nights in the forest and be a part of a complicated disaster and conflict scenario. They will be expected to demonstrate mastery of the knowledge acquired throughout the course. During the simulation, students will work in teams representing different humanitarian non-governmental organizations (NGOs) and will necessarily engage with a wide range of local and non-state actors (roles developed and filled by HSI faculty, alumni, and affiliates). After the completion of the simulation, students will be required to write a 10 to 15 page paper detailing a service delivery plan of response to the same theoretical humanitarian crisis.

At the completion of this course, the students will be able to fulfill the following learning objectives:

-Design a rapid health assessment in the field including applying appropriate epidemiological methods to assess population needs in crisis situations;

-Design, conduct, and analyze field interviews with key stakeholders in a humanitarian crisis - a cross-section of the local affected population, brigands and local militia, international heads of agencies, local and regional governmental officials, members of the local and international press, and representatives of the United Nations agencies;

-Synthesize the complex social, political, economic, geographic, and public health parameters that define the dynamic of a given humanitarian crisis.

Course Prerequisite: Students are required to successfully complete GHP 515, "Humanitarian Studies in the Field."

Course Fee: Students will be expected to contribute a $300.00 course fee to cover the per capita cost of this experience.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.




Course Evaluations


GHP520 The Ecology of Health in Development
Spring 2
Dr. R. Levins

2.50 credits
Lectures, seminars. Two 2-hour sessions each week

This course is a sequel to Human Ecology, GHP 253-fall II. It will be run as a semi-seminar course with about 1/3 lecture, 2/3 student-led discussions and reports. There will be a common core of general readings and then students will read different selections to contribute to the discussion.
Themes: The Eco-social Distress Syndrome, a multidimensional imbalance between our species and the rest of nature against the background of the conflicting demands for a rising and equitable standard of living for all and the constraints of sustainability.
Each kind of society has its own pattern of relations with the rest of nature including resources, waste, microorganisms, pests, habitats, climate and demography and its own ways of generating knowledge giving rise to distinct patterns of knowledge and ignorance.
Each habitat (natural or anthropogenic) provides human societies with its own constraints and opportunities and its own health spectrum.
Different strategies of development have differential effects on all of these. In order to span a wide range of alternatives situations, the course will be organized around selected geographic areas (the Lake Victoria basin, Thailand or the Philippines, Central America and the Caribbean), habitats (tropical forests, semi-arid savannas, coastlines, cities), health problems (malnutrition, malaria, cholera, emerging viruses) and development strategies for resource use, agricultural development, national science strategy (neo-liberal, nationalist, socialist) with an emphasis on the less familiar approaches, and international efforts to reconcile development with ecology.
Course notes: Minimum enrollment required. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP525 Econometrics for Health Policy
Spring
Dr. G. Fink

5 credits
Lectures. Two 2-hour sessions each week and one optional lab each week.

This is a course in applied econometrics for doctoral and advanced master level students. The course has two primary objectives: (1) to develop skills in linking economic behavioral models and quantitative analysis, in a way that students can use in their own research; (2) to develop students' abilities to understand and evaluate critically other peoples' econometric studies.

The course focuses on developing the theoretical basis and practical application of the most common empirical models used in health policy research. In particular, it pays special attention to a class of models identifying causal effects in observational data, including instrumental variable estimation, simultaneous equations and two-stage-least-squares, quasi-experiments and difference-in-difference method, sample selection, treatment effect models and propensity score methods.

Lectures will be complemented with computer exercises building on public domain data sets commonly used in health research. The statistical package recommended for the exercises is Stata.

Course Note: Students are expected to be familiar with probability theory (density and distribution functions) as well as the concepts underlying basic ordinary least square (OLS) estimation.

Course Activities: Optional review and computer lab sessions will be held.

Course Evaluations


GHP526 Research in Global Health and Population
Fall/Spring
Dr. D. Canning

5.0 credits
Lectures, seminars. One 1.5-hour session each week plus regular group meeting with instructor.

Course held at 9 Bow Street in Cambridge.

This course is designed for doctoral students as preparation for undertaking research. Students will gain familiarity with household level and aggregate level datasets commonly used in research in global health and population. They will learn how to access the datasets and merge different files to create data in a form that is ready for analysis. They will evaluate the quality of these datasets. Students will learn to read and critically evaluate recent research articles in the field of global health and population. Students will be expected to replicate the results in the papers studied and to provide and implement suggestions for improving the methodology used.
Students will form small groups (2-4) to undertake a group research project. Each group will design a proposal that poses a relevant research hypothesis and have data and a statistical methodology that is capable of answering the question posed. Students will carry out the analysis and write a joint group research paper. Students will gain experience in conducting research, writing up the results, and making presentations.

Course Note: This is a year-long course and it is primarily intended for second year doctoral students planning to proceed to undertake thesis research.

Course Evaluations


GHP527 Political Economy and Ethics of Health Reform:
Spring
Cases of Mexico and Taiwan

T. Bossert, W. Hsiao
5.0 Credits
Seminars, Case Studies. One 3-hour session each week.

In this advanced doctoral seminar course, students will be introduced to theoretical and methodological approaches from political science, economics and applied ethics to understanding the policy process that leads to (or obstructs) health system reform. The course will begin by linking broad theoretical approaches to a pair of in-depth case studies (Mexico and Taiwan) of health system change. As the students become more familiar with these approaches in particular contexts, the course will build parsimonious theories that can be applied more generally. Students will learn to use comparative, quantitative and formal approaches to analyze health system change. Students will learn how to craft important research questions and to use the appropriate evaluation methods to investigate the impacts of health system reforms. This class will help students identify potential research topics by showing where the frontier of knowledge is about political economy and health systems and the determinants of health systems performance.

Course pre-requisites: BIO 222 Basics of Statistical Inference, GHP 244 Health Sector Reform: A Worldwide Perspective, GHP 269 Applied Politics and Economics I: Political Economy of International Health, GHP 291 Microeconomics and Applications to Public Health in Developing Countries, GHP 525 Econometrics for Health Policy, HPM 243 Health Economics: Economic Analysis of the Health Care System and ID 292 Justice and Resource Allocation

Course Evaluations


GHP528 Quantitative Methods for Impact Evaluation
Spring 2
Dr. J. Cohen

2.5 credits
Lectures
One 3-hour session each week.


The objective of this course is to provide students with a set of theoretical, econometric and reasoning skills to estimate the causal impact of one variable on another. Students will be introduced to a variety of econometric techniques in impact evaluation and will learn both how to analyze a program or policy that happened in the past and how to design an evaluation of one that will happen in the future. We will go beyond questions about whether a particular policy or program had an impact on targeted outcomes and analyze the channels through which the impact was likely achieved. This will require familiarity with microeconomic theories of incentives, institutions, social networks, etc. Students will learn to critically analyze evaluation research and to gauge how convincing the research is in identifying a causal impact. They will use these skills to develop an evaluation plan for a topic of their own, with the aim of stimulating ideas for dissertation research.

Course Prerequisites: GHP 291 and GHP 525
Course Note: Priority will be given to GHP doctoral students in their last semester of course work. Prerequisite courses can be taken concurrently with GHP xxx. Ordinal grading option only.



Course Evaluations


GHP532 Introduction to Global Health Care Delivery
WinterSession
Dr. Joseph Rhatigan, Dr. P. Farmer

2.5 credits
January 2010: January 11-22, 2010
Lectures, case studies, laboratories. Eight 2-hour sessions each week.

This course will engage students in analysis of case studies that describe interventions to improve health care delivery in resource-poor settings. Class room discussion of these case studies will help illuminate principles and frameworks for the design of efficient and effective global health interventions. Through a focus on HIV, tuberculosis, and polio, these cases will allow students to carefully consider the question of how epidemiology, pathophysiology, culture, economics, and politics inform the design of interventions.

Course Evaluations


GHP532 Introduction to Global Health Care Delivery
Summer 1
Dr. J. Rhatigan, Dr. P. Farmer, Dr. W. Rodriguez, Dr. J. Mukerjee

2.5 credits
Summer 1
Lectures, case studies. Five 2-hour sessions each week.

This course will engage students in analysis of case studies that describe interventions to improve health care delivery in resource-poor settings. Class room discussion of these case studies will help illuminate principles and frameworks for the design of effective global health interventions. Through a focus on HIV, tuberculosis, and malaria, these cases will allow students to carefully consider the question of how epidemiology, pathophysiology, culture, economics, and politics inform the design and performance of global health projects.
Course Evaluations


GHP533 Advance Qualitative Methods & Data Analysis for Health Research
Spring 2
Dr. D. Halperin

2.5 credits
Two 2-hour sessions each week.
Some lectures at the beginning, though the course will mainly follow an advanced graduate student seminar format.

This course will provide students who have already conducted qualitative research in an area of global health (e.g., for their master's or doctoral thesis work) with the opportunity to consider how to most effectively analyze their data. It is assumed that students will also have had some prior training/classroom experience in designing and collecting qualitative research, such as an Introductory course at HSPH (or elsewhere) in Qualitative Research Methods. Didactic sessions will present and explore several of the leading directions in qualitative data analysis, from the fields of medical anthropology, sociology (i.e., grounded theory approaches), and social psychology. The main objective of the course will be to allow students to present their current work in progress and to receive systematic feedback from classmates and the instructor on their data analysis methodology.

Course Activities: Students will be expected to actively engage in the first six sessions, centered on relatively formal lectures about qualitative data analysis methodologies, as well as in the subsequent sessions, which will constitute more of an advanced graduate student seminar venue, in which each student will have nearly an hour to both formally present her/his data analysis content and process and to receive constructive input on how to improve the methodological approach. Students will also be required to submit a data analysis proposal.

Course Prerequisite: Prospective students wishing to enroll in GHP xxx must contact the instructor at dhalperi@hsph.harvard.edu or via phone at 432-7388.

Course Note: Enrollment limited to 15. Instructor's signature required.

Course Evaluations


GHP534 Introduction to Spatial Methods for Public Health
Spring 2
Dr. M. Castro

2.5 credits
Lectures, Seminars, Case Studies, Laboratory. Two 2-hour sessions and One 1-hour laboratory each week.

This is an introductory level course in the conceptual and analytic tools used to understand how spatial distributions of exposure impact on processes and patterns of disease. It covers methods that allow: (i) examination of patterns of health and disease in place and time, (ii) application of geospatial technologies and methods for epidemiology, (iii) analysis of time-space relations, (iv) identification of clusters and diffusion of disease, and (v) study of geographical epidemiology of selected infectious and noninfectious diseases.

Prerequisites:
Although there are no prerequisites for this course, students are highly encouraged to take one of the workshops on ArcGis offered by the Center for Geographical Analysis (CGA) - http://www.gis.harvard.edu

Course Activities: Assigned readings must be read in advance of class. Students will help summarize and lead discussions on several papers; complete a term project.

Course Note: Ordinal Grading only. Enrollment limited to 18 students.

Course Evaluations


GHP535 Applied Demography Analysis
Spring 1
Dr. A. Hill

2.5 credits
Lectures, seminars, case discussion, lab sessions.
One 2-hour session each week. Two 2-hour lab each week.

Course description:
GHP 535 is a second level class which builds on the material covered in the GHP 272 Foundations of Global Population and Health, GHP 220 Introduction to Demographic methods, GHP 506 Measuring population health and GHP 507 Population health risk factors. It has been designed for those seeking more advanced training in demographic methods and analysis and is particularly recommended for doctoral students in the Population and Reproductive Health Concentration. Students are introduced to the commonly used methods through review of the literature in interactive lectures, assigned readings (3-4 per session), case studies and web-based sources. The most important part of the course is the application of a variety of analytic methods to cases chosen mostly from Africa and the Middle East. The section of data sources provides a guide to the use of complex data sets including those provided by DHS-MACRO as well as other public domain surveys (e.g. UNICEF's MICS surveys). Together, these provide a graduate-level introduction to the concepts and application of standard as well as newer methods of demographic analysis, especially in populations where the data are incomplete or inaccurate. The emphasis throughout is on understanding the key relationships, models and assumptions used primarily for the analysis of levels, trends and differentials in fertility, mortality and migration in developing countries. Practical training will be provided through sessions in the MicroLab. There are class exercises which will be completed as short homework assignments. There will be a final paper that brings together the analyses completed throughout the course. Full details of the homework assignments, MicroLab exercises and final paper will be provided in separate notes distributed in class.

Prerequisites:
GHP 272 Foundations of global population and health (Bloom)
GHP 220 Introduction to demographic methods (Castro)

Course Note: Computer use of at least one software package such as SAS/STATA/SPSS. Facility with EXCEL spread sheets and graph production assumed.

Course Evaluations


GHP537 Public Health Field Research in Complex Emergencies & Conflict
Spring 1
Dr. M VanRooyen, Dr. P. Greenough

1.25 credits
Lectures, Case Studies: One two-hour session each week.

This course focuses on adapting epidemiological research methods to complex settings such as disasters and armed conflict. The course begins with a discussion of the complexities of the humanitarian environment, and then works through a series of case studies to teach students the approach to population sampling and field research methods.



Course Evaluations


GHP539 Social, Political & Econ Dimensions of Infect Dis in Dev Cntries
Fall 1
Dr. R. Cash, Dr. J. Weisfeld

2.5 credits
Lectures, case studies. Two 2-hour sessions each week.

The course reviews the epidemiology of infectious disease of greatest public health importance in developing countries in terms of distribution in time, place, and person. Context is emphasized in describing each of the conditions. Effects of social, economic, and cultural dimensions of these conditions will discussed as well as a framework for conducting these analyses. Case studies of different diseases from different countries are used throughout the course.

Course Evaluations


GHP540 Field Trip to Urban and Rural Bangladesh
WinterSession
Winter Session

Dr. O.M. Rahman, Dr. R. Cash
1.25 credits
Jan. 4 - Jan. 22, 2010

This mid-winter course to be held in Bangladesh will be coordinated by BRAC School of Public Health (BSPH). It will take advantage of the excellent opportunities available to study public health issues at BSPH and International Centre for Diarrheal Disease Research, Bangladesh (ICDDR,B), and international research with an excellent record of research going back 40 years. Prior to students leaving for Bangladesh, three seminars will be held at the HSPH in Fall 2 to introduce students to the health situation in Bangladesh. This will include demography, the success of different programs, research activities, and future challenges.
Course Note: Enrollment limited to 15; pass/fail grading option only; selected participants must attend the three seminars in Fall 2. Applications must be completed by October 8, 2009 and participants will be chosen by October 19, 2009.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP541 Health System Reforms in China: Seminar and Field Study
WinterSession
Winter session

Dr. Yuanli Liu
2.5 credits
Readings, lectures, group discussions, guest speakers, field trips. January 4 - 22, 2010 with preparatory seminars in December 2009.

Ever since publication of the 2000 World Health Development Report, there has been an increasing global interest in the critical role played by health systems in improving efficiency, equity, and quality of health care, and in achieving the Millennium Development Goals (MDGs). How health systems cope with the significant economic downturn is an important challenge facing many countries.

This course introduces students to the basic methods for conducting health system analysis, sensitizes the participants on the global debate on health system reforms, and help the students gain some hands-on experiences by interacting with the major stake-holders in China. China represents an interesting country for conducting the field study on health system reforms, not only because it is the world's largest country and has a wide spectrum of health and health system issues, but also because China is at a critical stage of implementing new rounds of reforms.

Students will be divided into theme groups. At the end of the trip, each group will submit a research paper (about 20 pages), analyzing a particular issue facing China's health system and proposing solutions. Each group will present and discuss the results of their diagnosis at one of the last days of the course in China, commented by invited policy experts and policy makers. Applications must be completed by Thursday October 8, 2009 and participants will be notified by October 19, 2009.

The program will require a minimum of eight students, with a maximum enrollment of fifteen.

Course Note: Enrollment limited to 15 students; pass/fail grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


GHP542 Field Trip to Brazil
WinterSession
Dr. M. Wilson

WinterSession
1.25 credits
January 4 - 20, 2010.
Lecture, Seminar, Case Study, Group Projects. Visits to labs, institutions, and field sites in urban and rural areas in the state of Bahia.

Brazil is the 6th largest country by area and has the largest population in Latin America. Although Brazil is the 8th largest economy globally, it has one of the highest levels of income inequality, which has a significant impact in public health. Infectious diseases remain an important cause of morbidity and mortality in Brazil. In this field trip to Brazil, students will learn about several infectious diseases that are endemic in Brazil and the biological, environmental and socioeconomic factors associated with their persistence and distribution.

Approximately 15 Brazilian students will also participate in the course. Professors from Harvard and faculty from Fiocruz and other Brazilian institutions will lecture and lead discussions. Lectures will be in English.

The David Rockefeller Center for Latin American Studies at Harvard University, which has an office in Săo Paulo, will facilitate work with Brazilian colleagues and institutions and assist with logistical arrangements. Lectures and discussions during the first week will focus on selected infectious diseases, such as HIV/AIDS, dengue, leptospirosis, schistosomiasis, and leishmaniasis, as well as social determinants of health and health policy in Brazil, and data sources and analysis. Students will also meet with researchers, public health workers and visit health care facilities and a favela in Salvador. During the second week students will work in small teams to develop proposals. The group projects will require a broad approach that takes into account the biological, geoclimatic, social, economic, cultural, political, and demographic factors associated with the disease. Each team will develop a research proposal that will address questions that need to be answered to prevent or reduce the morbidity or mortality from that disease. At the end opf the course students will present and discuss the results of their project with the entire class. Throughout this course the student will have an opportunity to interact with faculty from Harvard as well as faculty, public health workers, researchers, and students from Brazil.

Course Note: Enrollment limited to 15; pass/fail grading option only. Applications must be completed by Thursday, October 8, and participants will be chosen by October 19.

Course Evaluations


GHP543 Field Study on Public Health and Peace Building
WinterSession
Dr. C. Bruderlein

External instructor: Suneeta Kaimal
Winter Session Field Study : Indonesia
2.5 credits
Jan. 4 - Jan. 22, 2010

The aim of this interdisciplinary field study is to assess strategies for improving our response to major humanitarian challenges in conflict situations. The course will examine public sector planning in the fields of conflict management, public health and peacebuilding. In discussing options for operationalizing international humanitarian response to such conflicts, we will consider the potential synergies between public health, development, human rigths, and other relevant issues of concern. The potential impact of this event will be considered in terms of its epidemiological profile, local and regional response mechanisms, national and international security response, and international cooperation and governance.

The field study will begin with one week of preparatory class sessions at HSPH, followed by a two-week in-country visit including interviews of practitioners, site visits and group analysis. Students will be accompanied by course instructors. The course will require a minimum of nine students, with a maximum enrollment of 15. Enrolment to Fall Semester Course on Legal and Policy Challenges to Humanitarian Action is recommended.

Course Note: Enrollment limited to 15; pass/fail grading only. Applications must be completed by October 8 and participants will be notified by October 19.
Course Evaluations


GHP545 Clinical Research in Resource-Limited Settings: Tanzania
WinterSession
S. Kapiga

1. 25 credits
Lectures, class discussions, field trip

January 4 - 15, 2010: Field trip, lectures and class discussions in Tanzania

This 2-week course will introduce students to practical aspects of implementing clinical research and trials in Tanzania. Students will attend two introductory lectures during the first day in Tanzania on clinical research examining the associations between HIV, HSV-2 and other sexually transmitted infections. The lectures will include theoretical presentations by the instructor, and class discussions. The students will also receive information about the research site in Moshi, northern Tanzania, and detailed information about studies which have been conducted in Moshi in the past 5-6 years as well as ongoing research projects. During the rest of the period in Moshi, students will meet with project staff involved in the implementation of ongoing studies to learn about the practical aspects of conducting studies. Students may decide to focus on only certain aspects of the study or may rotate through various sections to gain a broad picture of implementation issues. At the end of the student's stay, they will meet in a group to present and share their experiences, and produce a written joint summary report.

Course Activities: Two weeks of field trip to Tanzania, (January 4-15, 2010). Applications must be completed by October 9, and participants will be chosen by October 20, 2009.

Course Note: Pass/Fail only.





Course Evaluations


GHP569 International Health and Education
Fall
Dr. M. Jukes

5.0 Credits
Lectures, Seminars. One 3-hour session each week.

Course not offered 2009-2010.

Taught at the Harvard Graduate School of Education. Classroom: Gutman 440.

Why is health important to the educator? This course looks at how poor health and nutrition is a problem for the education sector because it keeps children out of school or prevents them from learning when they do attend. It also explores policy options for schools to be part of the solution, by providing simple, cost-effective treatments that give the greatest benefits to the poorest students, and by providing the educational foundation for a healthy life. The course also looks at how the education sector can respond to the HIV/AIDS pandemics: How can schools provide for the needs of orphans and vulnerable children? Does sex education work? Theories of education for health and for community empowerment are examined along with the political and religious context for action. The aim of the course is to provide a thorough and critical foundation in theory and its application to planning, implementation, and monitoring programs to improve children's education through improved health.
Course Evaluations


GHP570 Population Change: Cause and Consequence
Spring
Dr. K. Hill

5.0 Credits
Lecutres, Seminars. Two 1.5-hour session each week.

Cross-listed and taught at the Harvard Kennedy School of Government. Classroom: Taubman 401.

The aim of this course is to provide students with an understanding of the factors that shape the size and structure of human populations and of how changes in population size and structure in turn influence a range of social and economic factors. The course will start with an introduction to the population history of the world, and an analysis of how the basic demographic forces of fertility, mortality and migration influence the size and age-sex structure of a population. The focus will then turn to the cultural, social and economic determinants of these three forces of fertility, mortality and migration, with a particular emphasis on the potential role of policies. The last part of the course will examine the consequences of changes in the size and structure of populations for a range of outcomes. Case studies will illustrate the interplay of causes and consequences. The course does not require any particular disciplinary background, though it will include a brief introduction to demographic measures and will assume a general interest in quantitative analysis.

Course Note: Ordinal grading option only.
Course Evaluations


HCM701 Organizational Behavior
Summer 1
Dr. D. Javitch

2.5 credits
Lectures, case studies. Fifteen sessions, field project. Summer 1.

This course focuses on the challenges of managing complex health care systems. We will explore the leadership and motivational skills relevant to performing as an effective leader, and discuss the different roles associated with managing the individual, the unit, the organization, and the larger system.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Ordinal grading option only. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM702 Marketing
Special
Ms. L MacCracken

2.5 Credits
Lectures, case studies. Academic Year 1.

This course is designed to introduce students to marketing applications for healthcare organizations. Using selected readings and case studies of healthcare and non healthcare marketing topics, students will learn to assess customer acquisition and retention strategies and tactics. The course develops a basic knowledge of marketing frameworks, including market intelligence, value propositions, product/service, price, location and promotion elements. Healthcare marketing topics include applications to customer channels, branding, and innovation. The class work includes cases, course discussion and a group project.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Ordinal grading option only.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM703 Perspectives in Public Health
Summer 1
Dr. M. Roberts

2.5 credits
Lectures, case studies. Fifteen sessions. Summer 1.

This course will use case studies focusing on important public health issues - such as smoking, gun violence and HIV prevention and treatment, to give students a sense of the complex environmental, social, and behavioral causes affecting the health of populations. It also explores a variety of analytical perspectives; political, legal, economic and epidemiological. Students will submit a short discussion memo and a longer paper analyzing a public health issue of their choice from various points of view.

Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.

Course Evaluations


HCM704 Managing Information in Health Care
Summer 2
Dr. D. Michaels (P), Dr. N. Kane (S)

2.5 credits
Lectures, case studies. Fifteen sessions. Summer 2.

This course will expose students to the concepts and knowledge involved in making strategic use of information technology (IT) in health care organizations. It will clarify how to establish IT linkages to business, planning, and governance. In addition it will introduce students to technology management through the analysis of the lifecycle of IT, systems integration, operational improvement through technology, and standards. The course focuses on key health care implications and the impact of IT upon quality, cost, and operations.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Ordinal grading option only. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM706 Physician Leadership Seminar
Special
Mr. J. Conway

2.5 Credits
Lectures, case studies. Academic Year 2.

This course focuses on the leadership and managerial skills that are most practical and relevant to physician leaders. Cases, articles, discussions, and guest speakers provide participants with insight into the roles, challenges, and success requirements of executives and clinical leaders. A framework for leadership is introduced and successive sessions take selected elements of the framework for further study. Sessions include; leadership theory and current challenges professionally and personally; business and operational planning grounded in ethical practical; governance and health care leadership in light of contemporary challenges and opportunities; communication, teamwork and integrative leadership; project and process management oriented to impact and results; the dramatically changing work force and realizing the potential of diversity; and human resources, developing others, and personal development.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Ordinal grading option only. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM707 Health Care Management Practicum
Special
Dr. D. Soodalter-Toman

5.0 credits
Seminars. Off-site field practicum. Academic Year 2

The Practicum provides students with an opportunity to directly apply the knowledge and skills gained throughout the MHCM program and this course, along with their experience and expertise, by completing a field project in a healthcare organization. The project will involve the development and implementation of a major change initiative or new service line.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Ordinal grading option only. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM709 Communication Skills for Managers
Special
Mr. M. Campbell

1.25 credits
Seminars. Academic year 1

Health care executives are increasingly called upon to communicate with a wide range of internal and external groups. This course will focus on the competencies necessary to deliver successfully presentations in a variety of situations that involve subordinates, superiors, with the board, peers, and external constituencies like the media. Students will learn to analyze challenging communication situations, prepare for contingencies, think on their feet, answer difficult questions and develop poise and confidence under pressure. The principles and techniques of this course will be applied to mini-projects that the students will deliver off-site. Students will be responsible for reporting an analysis of these projects for review by the course instructor.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Ordinal grading option only. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM719 Financial Transactions and Analysis
Special
Dr. H. Rivenson

2.5 credits
Lectures, case studies. Academic Year 1.

This intensive course introduces concepts of financial accounting to the non-accountant user of financial information. Basic accounting transactions, statement preparation and concepts of accrual versus cash accounting are presented in the first half of the course. The remainder of the course focuses on financial analysis of a variety of health care organizations.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Similar to HPM219 - adapted for the non-residential program. Completion of Anthony's Essentials of Accounting before class begins required. Working ability with spreadsheets also required. Ordinal grading option only. (5.06)



Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM720 Cost Accounting and Control Systems
Special
Mr. R. Siegrist

2.5 credits
Lectures, case studies. Academic Year 1.

This course is designed to introduce students to cost accounting and management control concepts and uses for health service organizations. The first part of the course develops a basic knowledge of cost accounting, including full and differential costing techniques. The remainder of the course focuses on management control structure and process and addresses topics such as responsibility accounting, budgeting, reporting and variance analysis.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Similar to HPM 220 - adapted for the non-residential program. Ordinal grading option only. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM722 Financial Management of Health Care Organizations
Summer 2
Dr. H. Rivenson, Ms. D. Puhy

2.5 credits
Lectures, case studies. Five 2-hour sessions each week.

Topics include financial management of working capital and investment decision models, long term capital structure and mergers and acquisitions of health care organizations. Materials will primarily involve cases about a range of health care organizations (hospitals, insurers/ managed care plans, neighborhood health centers, physician groups, home health agencies, etc.).
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management required; ordinal grading option only. Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM731 Competitive Strategy Determination
Special
Dr. N. Kane

2.5 credits
Lectures, case studies. Academic Year 2.

This course focuses on the conceptual framework needed to plan for the long-term viability of health care organizations. Using selected readings and case studies of both health care and non-health care organizations, students will learn to appreciate the concepts of competitive strategy and competitive advantage primarily through practice in analysis. The objective is to provide students with the conceptual tools and the practical skills to enable them to formulate, execute, and evaluate organizational strategy.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Ordinal grading option only. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM732 Operations Management in Service Delivery Organizations
Summer 1
Dr. J. Pliskin

2.5 credits
Lectures, case studies. Fifteen sessions, field project. Summer 1.

Operations management is concerned with evaluating the performance of operating units, understanding why they perform as they do, designing new or improved operating procedures and systems for competitive advantage, making short-run and long-run decisions that affect operations, and managing the work force. To understand the role of operations in any organization, a manager must understand process analysis, capacity analysis, types of processes, productivity analysis, development and use of quality standards, and the role of operating strategy in corporate strategy. The course will also present the focused management approach which can help an organization achieve much more with existing resources.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Similar to HPM 232 - adapted for the non-residential program. Ordinal grading option only. (10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM755 Provider Payment Systems and Policy
Special
Dr. K. Quigley

2.5 credits
Lectures, seminars, case studies. Academic year 2.

The admonition "Follow the money" is good advice to anyone seeking a deeper understanding of any health care system. Money is a major tool for shaping the delivery of health care, for both good and ill. This course will follow the money as it flows through provider payment systems, and examine the options for managing those flows to encourage more cost-effective use of resources. Topic will include payment methods for hospital care, physicians, pharmaceuticals, and new technologies. The second half of the course will address the issue of health policy and regulation - the legal framework in the US, how policy is developed and applied to health care issues, and how individuals and groups can influence the policy process.

Materials will involve cases about a range of health care organizations (hospitals, insurers/managed care plans, physician groups) supplemented by background readings. Guest speakers will provide a first-hand perspective and particular expertise on selected topics.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HCM757 Quality Improvement & Quantitative Methods in Quality Management
Summer 2
Dr. M. Bloomberg , Dr. M. Pagano

5.0 Credits
Lectures, case studies; Summer Session 2 & Academic Year 2;

This course in quality improvement and quantitative tools is designed for the physician executive or manager whose responsibilities include either oversight or direct involvement in quality management and improvement in a health delivery or health financing organization. Using selected readings case studies, lecture presentations and extensive classroom discussions, students will learn both the conceptual and practical aspects of improving health care quality.

Course Note: Enrollment in part-time non-residential Masters in HCM required; ordinal grading option only.

Course Evaluations


HCM758 Field Project in Quality Improvement
Special
Dr. J. Silobrcic, Dr. N. Kane

2.5 Credits
Lectures, facilitated work/discussion sessions. Academic Year 2.

This course will provide physician executives with practically-oriented insights into quality improvement in healthcare organizations, based on the study of lessons from students' own quality-related "field projects" performed during the 2nd academic year of the MHCM program. At the end of this course, students will understand their own roles in quality improvement and management, and be able to lead their organizations' efforts in those areas, using a methodical approach and process: from conception, design and initial planning, to implementation, measurement, analysis and redesign. The course objective is not to make students expert in each of these components of the QI process, but to enable them to provide effective leadership to organizations, teams and colleagues carrying out these activities.

Course Note: Enrollment in part-time non-residential Masters in HCM required; ordinal grading option only.

Course Evaluations


HCM778 Skills & Methods of Hlth Care Negotiation & Conflict Resolution
Fall
Dr. L. Marcus, Dr. B. Dorn

1.25 credits
Lectures, case studies.

This course introduces students to the theory and practice of negotiation and conflict resolution. Particular emphasis is placed on integrating analytic skills, negotiation techniques and conflict resolution methods into the practice of health care management. Much of the class is devoted to simulation exercise in which general concepts and methods are demonstrated and practiced. These exercises model disputes typical of health care settings and health care management problems. The debriefings that follow each exercise offer individual feedback, as well as the opportunity to examine applied issues of organizational communication, system design and conflict. By the end of the course, students will have knowledge of the overt and covert causes of conflict, concepts for analyzing disputes and a variety of methods useful for preventing, resolving and when necessary, initiating a conflict.
Course Note: Enrollment in the part-time, non-residential Masters in Health Care Management program required. Similar to HPM 278 - but more extensive than traditional course. Ordinal grading option only. (7.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM205 Economic Analysis for Public Health
Fall
Dr. M. Roberts

5 credits
Course not offered 2009-2010
Lectures. Two 2-hour sessions each week.

Provides an introduction to the basic principles of economics and economic analysis, particularly as they apply in the public health field. A systematic introduction to microeconomic theory including the determinants of supply and demand, the theory of markets, and the concept of economic efficiency. Specific topics in health care economics include the demand for health care, insurance, and the market for physician services.
Course Note: May not be taken for credit by students who previously have taken HPM206. (6.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM206 Economic Analysis
Fall
Dr. D. Hemenway

5 credits
Lectures. Three 2-hour sessions each week.

Designed to bring students to an intermediate-level understanding of microeconomic theory. Emphasizes the uses and limitations of the economic approach, with applications to public health. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM208 Health Care Regulation and Planning
Spring
Dr. K. Swartz

5 credits
Not offered 2008-2009
Lectures. Two 2-hour sessions each week.

Examines issues under discussion for U.S. health care reform: health insurance, financing, methods for controlling health care costs, incentives for hospitals and physicians, medicare long-term care and the pharmaceutical industry. Competitive versus regulatory approaches are explored, as part of analyzing the role of government and the private sector. The distributional consequences of various programs and methods receive special focus. Five homework memos of 2 pages will be required in addition to a midterm and final exam.
Course Note: HPM205, HPM206 or signature of instructor required.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM209 Economics for Health Policy
Summer 2
Dr. M. Rosenthal

2.5 credits
Lectures, seminars. Five 2-hour sessions each week.

Students will learn how to analyze important health policy issues through the application of basic economic principles. No previous economics training is required. The course will begin with an introduction to the U.S. health care "system" because we will be using examples drawn almost exclusively from the American context. The concepts we will be learning, however, are widely generalizable and students whose interests and experiences extend beyond the U.S. are welcomed. Among the topics we will discuss are health insurance coverage, benefit design, physician payment incentives, public reporting of quality information, and the pharmaceutical industry.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.

Course Evaluations


HPM212 Program Evaluation in Health Policy
Fall
Instructor to be announced

5 credits
Course not offered 2007-2008
Lectures, case studies. Two 2-hour sessions each week.

Course provides a one-semester overview of evaluation for those likely to participate in the design or implementation of evaluations in private organizations or government agencies. Topics include establishing the scope for an evaluation, evaluation design, data and measurement issues, issues in inference (appropriate controls, changing program design and unique local circumstances), and problems of assuring the accuracy, relevance and credibility of findings. Both quantitative and qualitative methods are addressed. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM213 Public Health Law
Spring 1
Dr. M. Mello

2.5 credits
Seminars. Two 2-hour sessions each week.

This course examines the many ways in which the law impacts the public health. Among the questions explored are: What authority does the government have to regulate in the interest of public health? How are individual rights balanced against this authority? What are the promises and pitfalls of using laws and litigation to achieve public health goals? The course investigates these issues as they operate a range of specific contexts in public health and medical care, including the control and prevention of HIV/AIDS and other communicable diseases, tobacco regulation, rights to have and refuse medical care, reproductive health, and lawsuits against tobacco and gun companies. The course emphasizes constitutional law, but also touches on criminal law, tort law and intellectual property law. Instruction is through interactive lectures with a significant amount of class discussion. Most classes will revolve around two to three legal cases. The previous year's syllabus is available on the course website.

Course Note: No previous background in law is needed.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.


Course Evaluations


HPM219 Financial Transactions and Analysis
Fall 1
Dr. H. Rivenson

2.5 credits
Lectures, case studies. Three 2-hour sessions each week.

This intensive course introduces concepts of financial accounting for the non-accountant user of financial information. Basic accounting transactions, statement preparation, concepts of accrual vs. cash accounting, and nonprofit healthcare accounting are presented in the first half of the course. The second half focuses on statement analysis in a variety of health care organizations.
Course Note: Course restricted to students enrolled in MPH/CMP and MS2/HPM programs. Other students allowed with signature of course instructor if space permits; Completion of Robert Anthony's Essentials of Accounting before class begins required. Working ability with spreadsheets is also required; no auditors. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM220 Financial Management and Control
Fall 2
Dr. P. Campbell

2.5 credits
Lectures, case studies. Three 2-hour sessions each week.

The course is designed to introduce students to cost accounting and management control concepts and uses for health service organizations. The first part of the course develops a basic knowledge of cost accounting, including full and differential costing techniques. The remainder of the course focuses on management control structure and process and addresses topics such as responsibility accounting, budgeting, reporting and variance analysis.

Course Note: HPM 219 is recommended but not required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM222 Financial Management of Health Care Organizations
Spring 2
Dr. H. Rivenson, Ms. D. Puhy

2.5 credits
Lectures, seminars, case studies. Two 2-hour sessions each week.

Topics include financial management of working capital and investment decision models, long term capital structure and mergers and acquisitions of health care organizations. Materials will primarily involve cases about health care organizations.
Course Note: This course will be taught at an introductory/intermediate-level and is designed to be complementary to HPM 219 and HPM 220. HPM 219 and HPM 220 required. No auditors.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM223 Public Speaking for Managers
Fall 2
Mr. M. Campbell

1.25 credits
Seminars. One 2-hour session each week.

This course gives the student the opportunity to develop skills in oral communication. Emphasis is placed on the techniques most useful to managers. Students will give and critique their own presentations in a supportive classroom environment.
Course Note: Pass/Fail option only; enrollment limited to15 students. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM223 Public Speaking for Managers
Spring 2
Mr. M. Campbell

1.25 credits
Seminars. One 2-hour session each week.

This course gives the student the opportunity to develop skills in oral communication. Emphasis is placed on the techniques most useful to managers. Students will give and critique their own presentations in a supportive classroom environment.
Course Note: Pass/Fail option only; enrollment limited to15 students. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM227 The Economics of Health Policy
Spring
Cross-listed at KSG as HCP-272

Dr. J. Newhouse
5 credits
Seminars. Two 1.5 hour sessions each week.

Taught at the Harvard Kennedy School of Government. Classroom: Littauer 280.

Policy issues related to the following topics are considered in the course: demand for medical care services, especially as a function of insurance; demand for insurance and issues of selection; reimbursement policies of Medicare toward both hospitals and physicians; effects of health maintenance organizations and their reimbursement by Medicare; quality of care and malpractice. The perspective will generally be that of American federal policy, although state and local perspectives will receive some attention. International students are welcome.
Course Note: HPM205, HPM206 or equivalent or signature of instructor required; ordinal grading option only; cross-listed course, HSPH students must register for HSPH course.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM228 Intro to the New American Health Care System: Law,Policy,Mngmnt
Fall 2
Mr. G. Moseley

2.5 credits
Lectures. Two 2-hour sessions each week.

This course is a comprehensive introduction to the full scope of the current health care system in the U.S. Because the system is rapidly evolving, the course is new every year. It is ideal for students who are early in their health care careers or who want a refresher on the changes that have occurred recently. International students and mid-career physicians have found great value in the course.

After tracing the Historical Development of health care in the U.S., we look at the Societal Beliefs and Values that underlie the system. There is a good review of the Key Players and Stakeholders in the system, and how they interact with each other. Individual classes are devoted to Hospitals and the Health Professions. The Managed Care Industry and its practices are also put under a microscope.

For the most expensive health care system in the world, it is important to learn How It is Financed and what is being done to Control Its Soaring Costs. We also will examine the Quality of Care provided by the system and who has Access to it. There is a strong emphasis on the Health Policies that govern the system and the Processes by which those policies are made.

Throughout the course, we will notice the many Legal Issues that are shaping the system, particularly in the areas of Antitrust, Fraud and Abuse, and Taxation. We will spend one session comparing the U.S. system to the way health care is financed and delivered in Other Industrialized Countries. Three classes will address special challenges facing the health care system - last year they were Consumer-Driven Health Care, Medical Technology, and Elder/Long-Term Care.

The learning style in this course involves a lot of dialogue among students and instructor, case studies, guest speakers, and classroom exercises. There are two very short written assignments and a structured final paper requirement.

Course Note: Auditors are not permitted.


Course Evaluations


HPM230 Managing People in Health Care Organizations
Spring 2
Mr. G. Moseley

2.5 credits
Seminars. Two 2-hour sessions each week.

Health care is a labor-intensive industry; human resource costs account for over 70% of the U.S. health care budget. At some point in their careers, most HSPH graduates will be responsible for directing the work activities of other people. In this course, they will learn basic strategies and tactics for achieving maximum productivity and contentment from employees in health care settings.

The course will examine all the critical managerial challenges along the employment continuum, from Recruitment and Hiring through Performance Appraisal to Layoff or Firing. We will learn about the human desires that Motivate Behavior and how to take advantage of them in the workplace. The skills and traits associated with Effective Leadership will be studied. These include the important talents of Delegating to Subordinates and Handling Employee Problems.

In the most exciting part of this course, students will become familiar with state-of-the-art managerial concepts like Organizational Culture, Managing Change, and Learning Organizations. We will spend time learning how teams form and function in a health care setting, especially when composed of multiple disciplines. Including other topics receiving special attention are: Facilitating Communication, Resolving Conflict, Working with Labor Unions, and Using Power in the Workplace.

One class will be devoted to the role of Compensation in managing people, particularly the current hot topic of Pay-for-Performance. During another session, we will explore the twin issues of Managing Physicians and Physicians as Managers. The aspects of Sexual Harassment and Substance Abuse unique to health care organizations are the focus of another class. Throughout the course, reference is made to the Legal Implications of employment decisions by managers.

The learning style in this course involves a lot of dialogue among students and instructor, case studies, and role plays. During the course, students keep a journal of their developing thoughts on people management and conduct a field interview with a practicing people manager.

Course note: No Auditors

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.

Course Evaluations


HPM231 Competitive Strategy
Spring 1
Dr. N. Kane, Mr. J. Clark

2.5 credits
Case studies. Two 2-hour sessions each week.

Focuses on the conceptual framework needed to plan for the long-term viability of health care (and other) organizations. Using selected readings and case studies of health care organizations, students will learn to appreciate key strategic concepts such as environmental analyses, strategic planning, and balanced scorecards, primarily through practice in analysis. The objective is to provide students with the conceptual tools and the practical skills to enable them to formulate, evaluate, and implement organizational strategy.
Course Note: No auditors. (5.03)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM232 Operations Management in Service Delivery Organizations
Spring 1
Dr. E. Litvak

2.5 credits
Lectures, case studies. Two 2-hour sessions each week.

Operations management is concerned with evaluating the performance of operating units, understanding why they perform as they do, designing new or improved operating procedures and systems for competitive advantage, making short-run and long-run decisions that affect operations, and managing the work force. To understand the role of operations in any organization, a manager must understand: process analysis, capacity analysis, types of processes, productivity analysis, and the role of operating strategy in corporate strategy. Case studies will be used to introduce students to a wide range of practical operational issues in healthcare delivery. Students will also be introduced to a new
variability based methodology and to the quantitative techniques to reduce cost while maintaining or even improving quality of care. Problem oriented software will be used for some of these scenarios. (5.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM233 Strategic Marketing Management in Health Systems
Spring
Dr. J. Porter

2.5 credits
Seminars, case studies, lectures. One 2-hour session each week.

Examines marketing within a strategic framework across the public and private sectors, domestic and international health systems, and social marketing contexts. Marketing management, research, and strategy techniques are discussed and applied to program design, business planning, and implementation issues. Course emphasizes analytic skills development in marketing.

Course Note: Ordinal Grading Option Only

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM235 Managing Health Care Costs
Fall 2
Dr. J Levin-Scherz

2.5 Credits
Lectures, Seminars, Case Studies. Two 2-hour sessions each week.

Health care inflation in the United States--and in many other countries--has consistently exceeded overall inflation since the mid 1990s, and employers, government, and individuals are increasingly reluctant to pay increasing amounts for health care coverage. Employer-based health care coverage has diminished, and escalating health care costs threaten other important programs of local and state governments. For example, estimates suggest that the Medicare Trust Fund will be depleted long before the Social Security Trust Fund, suggesting that Medicare will require substantial cuts or additional governmental subsidies. Health care affordability is a major subject in the national political debate.

This course will use lectures, case studies and a simulation to examine the major factors that determine the cost of health care in the United States, and the impact of these forces on system stakeholders. We will review the fundamentals of managed care, with a focus on some of the practical challenges and major public policy issues that arose with the growth and decline of managed care. We will review the advantages, disadvantages and feasibility of different approaches to moderating rising costs, including benefit design, medical management, utilization review, provider profiling and reporting, and regulatory action. We will also review efforts to improve health care affordability in other countries. Students will be encouraged to develop their own critical assessment of the prospects of using these techniques to control health care spending and to improve access and quality of care. A number of guest speakers will provide a first-hand perspective on some topics.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM243 Health Economics: Economic Analysis of the Health Care System
Spring 1
Dr. W. Hsiao

2.5 credits
Lectures. Two 2-hour sessions each week.

Introduces health economics, using economic analysis to examine major health systems of advanced nations and comparing them. Topics include: structure of national health systems, market competition, market and government failures, control of health cost inflation and managed competition.
Course Note: HPM 205 or HPM 206 or signature of instructor required. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM245 Public Health Leadership Skills
WinterSession
Dr. L. Marcus, Dr. B. Dorn

2.5 credits
Lectures, laboratories. Five 7-hour sessions.

It is not uncommon for HSPH graduates to find themselves in significant public health leadership positions. For students who foresee such responsibility on their career path, this course provides a focus and framework to integrate the overall HSPH experience into a leadership trajectory. Though the course is primarily practice oriented, it will cover key aspects of leadership theory and concepts. With a focus on the pragmatic problems and challenges of assuming a prominent role in the public health system, the course also incorporates the theme of assuming a prominent role in the public health system, as in "what I wish I knew before I became a state public health commissioner." The class includes a combination of lecture, discussion, role play exercises and on-the-spot presentations and critiques by instructors and students.

Course Note: Enrollment limited to 30 students. Acceptance into the course is based upon submission to the instructors of a brief essay entitled "Why Leadership Course is Imporant to Me". Please email Kim Kaminsky for details: kkaminsk@hsph.harvard.edu. Instructor's permission required. No auditors. Similar to HPM 278 - but more extensive than traditional course. Ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM246 Seminar in Health Policy
Fall/Spring
Cross-listed at KSG as HCP-597 and HCP-598 and at FAS as HP-2000

Dr. J. Newhouse, Dr. R. Frank
10 credits, given at end of last semester
Seminars. Two 2-hour sessions each week.

Taught at the Harvard Kennedy School of Government. Classroom: Taubman 301.

This course is restricted to doctoral students. Topics covered will include the financing and organization of health care, medical manpower, medical malpractice, technology assessment, prevention, mental health, long-term care, and quality of care.
Course Note: Requirement for doctoral students in the HPM department; signature of instructor required for those who are not doctoral candidates in the HPM department; the course meets at the John F. Kennedy School of Government. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM253 Improving Quality in Health Care
Summer 2
M. Bisognano

2.5 credits
Lectures, seminars. Fifteen 2-hour sessions.

This course is designed for practicing physicians and those with an interest in health care management. It will explore both the theory and practical methods being employed to make improvement in health systems. Clinical cases, organizational lessons and interactive learning modules will guide the learners to an understanding of the necessary elements for improvement and how to identify and eliminate barriers to change.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM255 Payment Systems in Healthcare
Spring 2
Ms. D. Devaux

2.5 credits
Lectures, seminars and case studies. Two 2-hour sessions each week.

The admonition "Follow the money" is good advice to anyone seeking a deeper understanding of any health care system. Money is a major tool for shaping the delivery of health care, for both good and ill. This course will follow the money as it flows through provider payment systems, and examine the effects of these flows on those who give, receive and pay for health care. Topics will include payment methods for hospital care, physician, pharmaceuticals, dental services, and new technologies. Cross-national examples will be used occasionally to gain greater understanding of some of the challenges that face all health care systems in designing successful provider payment systems. Guest speakers will provide a first-hand perspective on selected topics.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM275 Health Policy Issues: Access to Dental Services
Fall 2
Dr. C. Douglass

2.5 credits
Lectures, seminars. Two 2-hour sessions each week.

Taught at the Harvard School of Dental Medicine. Classroom: RB202.

This course uses examples and issues such as access to dental care as a strategy for understanding health policy and public health program development and management at the local, state, and national levels. The objectives are: to understand the market for health services and the process of health policy development; to apply the health policy process and community health program planning methods to dental services program development; and to identify possible linkages between the public health system and the (dental) health services delivery system.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM276 Methods and Application in Health Services Research
Summer 1
Dr. A. Epstein, Dr. J. Weissman

2.5 credits
Lectures, seminars, case studies. Five 1.75-hour sessions each week.

Methods and Applications in Health Services Research introduces student to the interdisciplinary field of health services research. The course covers theory, methodology, and applications using a highly interactive teaching approach. Individual sessions will be devoted to research design, analyses of large databases, cost-effectiveness analyses, survey methodology, assessment of health status, assessment of quality, measurement of racial, ethnic, and socioeconomic disparities, appropriateness of care, risk adjustment, and statistical techniques pertinent to health services research. There will be one or more sessions reviewing managerial applications such as case management, use of hospital information systems, and targeting for high-risk patients.

The course will also include class sessions and exercises devoted to critique of journal articles. These will supplement didactic presentations and will target development of skills in performing research and writing papers. In the final part of the course, students will work in small groups to critique a "grant proposal" designed to study an important problem in health services or health policy research. Each group of students will write up their critique in a format typical for a federal study section. This effort is designed to educate students on important aspects of grant writing.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM277 Current Issues in Health Policy
Summer 1
Dr. A. Epstein, Dr. T. Komaroff

2.5 credits
Lectures, seminars, case studies. Five 1.75-hour sessions each week.

Current Issues in Health Policy introduces students to the major health policy issues facing the United States today. The course focuses on the roles of hospitals, doctors, private and government insurance, and different systems for organizing and financing care (such as traditional fee-for-services, HMOs, and other forms of "managed care"). Individual sessions in the course will be devoted to topics such as malpractice, policy issues related to pharmacologic therapy, physician payment, academic health centers, workforce, physician profiling, managed care, the uninsured, Medicare, and Medicaid.

Taken together, the course sessions are designed to provide both a general background of the health care system and knowledge of many of the cutting-edge issues that are on the forefront of the nation's health policy agenda. The course will provide insight into how and why particular health policies are developed. It will focus on what the major policy questions are, and present examples of health services research methodology. However, the course concentrates much more on policy questions than methodological techniques.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM278 Skills & Methods of Hlth Care Negotiation & Conflict Resolution
Spring 2
Dr. L. Marcus, Dr. B. Dorn

1.25 credits
Lectures, seminars. One 2-hour session each week.

This course introduces students to the theory and practice of negotiation and conflict resolution. Particular emphasis is placed on integrating analytic skills, negotiation techniques and conflict resolution methods into the practice of public health. The course is built around the concepts and methods of “The Walk in the Woods” – a four step method of interest-based negotiation model developed by the instructors. Much of the class is devoted to simulation exercise in which general concepts and methods are demonstrated and practiced. These exercises model disputes typical of health care settings and public health problems. The debriefing which follows each exercise offers individual feedback, as well as the opportunity to examine applied issues of organizational communication, system design, and conflict. By the end of the course, students will have knowledge of the overt and covert causes of conflict, concepts for analyzing disputes and a variety of methods useful for preventing, resolving and when necessary, initiating a conflict.

Course Note: Enrollment limited to 48 students. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM283 Advanced Skills and Methods of Health Care Negotiation
Spring 2
Dr. L. Marcus, Dr. B. Dorn

1.25 credits
Lectures, seminars, case studies
One 2-hour session each week

This course builds upon the basic Skills and Methods course, providing students the opportunity to more deeply explore the concepts and techniques of negotiation and conflict resolution. (Students enrolled in this course must be enrolled simultaneously in the basic course, which meets on the same day and in the two hour time slot just prior to this course session.) For example, on topics of negotiation, students in the advanced class will examine methods to create common ground and agreement on highly polarized issues upon which parties are contentiously divided. This advanced class will also more thoroughly develop practice skills, including strategies and techniques of mediation. This additional material is covered by a combination of lecture, in class discussion, and advanced simulation and role play exercises. Enrollment limited to 24. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM290a Applied Research and Practice in Health Policy and Management
Fall 1
Ms. N. Turnbull, M. McCormack

Four 2.5 credit sections (Fall 1, Fall 2, Spring 1, Spring 2).
All second-year students in the HPM MS2 program will be required to register for the HPM290 (Fall 1) section and for two of the other three sections.
Student will receive a grade for each section given at end of each semester.
Field work and 1-2 two-hour session each month. Fieldwork takes place for 8-10 hours each week.

Allows students to apply their coursework to concrete problems. Students carry out a research project, perform a policy analysis or conduct a management study on behalf of an individual or institutional sponsor. Students work with sponsors to develop individual projects. Students meet 1 or 2 times per monthl to discuss progress and hear guest speakers to strengthen practical career skills. At the conclusion of the course, students prepare oral and written reports summarizing their project results.

Course Note: Open only to students in the second year of the two-year Master of Science in Health Policy and Management; ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM290b Applied Research and Practice in Health Policy and Management
Fall 2
Ms. N. Turnbull, M. McCormack

Four 2.5 credit sections (Fall 1, Fall 2, Spring 1, Spring 2).
All second-year students in the HPM MS2 program will be required to register for the HPM290 (Fall 1) section and for two of the other three sections.
Student will receive a grade for each section given at end of each semester.
Field work and 1-2 two-hour session each month. Fieldwork takes place for 8-10 hours each week.

Allows students to apply their coursework to concrete problems. Students carry out a research project, perform a policy analysis or conduct a management study on behalf of an individual or institutional sponsor. Students work with sponsors to develop individual projects. Students meet 1 or 2 times per monthl to discuss progress and hear guest speakers to strengthen practical career skills. At the conclusion of the course, students prepare oral and written reports summarizing their project results.

Course Note: Open only to students in the second year of the two-year Master of Science in Health Policy and Management; ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM290c Applied Research and Practice in Health Policy and Management
Spring 1
Ms. N. Turnbull, M. McCormack

Four 2.5 credit sections (Fall 1, Fall 2, Spring 1, Spring 2).
All second-year students in the HPM MS2 program will be required to register for the HPM290 (Fall 1) section and for two of the other three sections.
Student will receive a grade for each section given at end of each semester.
Field work and 1-2 two-hour session each month. Fieldwork takes place for 8-10 hours each week.

Allows students to apply their coursework to concrete problems. Students carry out a research project, perform a policy analysis or conduct a management study on behalf of an individual or institutional sponsor. Students work with sponsors to develop individual projects. Students meet 1 or 2 times per monthl to discuss progress and hear guest speakers to strengthen practical career skills. At the conclusion of the course, students prepare oral and written reports summarizing their project results.

Course Note: Open only to students in the second year of the two-year Master of Science in Health Policy and Management; ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM290d Applied Research and Practice in Health Policy and Management
Spring 2
Ms. N. Turnbull, M. McCormack

Four 2.5 credit sections (Fall 1, Fall 2, Spring 1, Spring 2).
All second-year students in the HPM MS2 program will be required to register for the HPM290 (Fall 1) section and for two of the other three sections.
Student will receive a grade for each section given at end of each semester.
Field work and 1-2 two-hour session each month. Fieldwork takes place for 8-10 hours each week.

Allows students to apply their coursework to concrete problems. Students carry out a research project, perform a policy analysis or conduct a management study on behalf of an individual or institutional sponsor. Students work with sponsors to develop individual projects. Students meet 1 or 2 times per monthl to discuss progress and hear guest speakers to strengthen practical career skills. At the conclusion of the course, students prepare oral and written reports summarizing their project results.

Course Note: Open only to students in the second year of the two-year Master of Science in Health Policy and Management; ordinal grading option only.

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM292 Research Ethics
Spring 2
S. Putney

1.25 credits
Course canceled for 2006-07
Lectures. One 1-hour session each week.

This course is required for all students engaged in studies supported by the National Institutes of Health, and is open to everyone. The course reviews a series of ethical issues that arise in the conduct of research. Topics will include informed consent, disclosure of conflicts of interest, multiple authorship issues, issues in mentoring, including gender and race-based discrimination, and the federal oversight process.
Course Activities: Multiple lecturers will conduct interactive sessions. (5.06)

Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM296 Doctoral Seminar in Health Economics
Spring
Cross-listed as KSG as HCP-581 and at FAS as EC 2460

Dr. J. Newhouse
2.5 credits
Seminars. One 2-hour session each week.

Explores frontier work in the field of health economics. Focuses on learning advanced theories and economic models useful for policy analysis, and on helping students develop dissertation and/or research topics. Students enrolled for credit are expected to present original research at the end of the semester.
Course Note: For doctoral candidates or very advanced master's degree students; a graduate-level microeconomics course is required; signature of instructor required indicating suitable background. Course meets for 4 weeks at Boston University, five weeks at HSPH, and 4 weeks at the Kennedy School of Government.


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM299 Research with Large Databases
Summer 2
Dr. J. Ayanian, Dr. E. McCarthy

2.5 Credits
Lectures. Five 2-hour sessions each week.

Research with Large Databases addresses potential uses of existing large administrative, clinical, and survey databases to study important questions regarding clinical risk factors, treatment, outcomes and health policy. Strengths and limitations of large databases that are commonly used for research will be considered, and special attention will be devoted to large federal databases that are readily available to new investigators. Practical issues in obtaining, linking and analyzing large databases will be emphasized in the course and key statistical issues will be addressed, including risk-adjustment and sampling weights. Students will evaluate published studies based on large databases and develop a proposal for analyzing a specific research question with a large database.
Course Notes: EPI208 or EPI200 and BIO206 or BIO202 required; no auditors. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM300 Independent Study/ Tutorial
Fall 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of the regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/fail only; signature of instructor required.

Course Evaluations


HPM300 Independent Study/ Tutorial
Fall
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


HPM300 Independent Study/ Tutorial
Fall 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


HPM300 Independent Study/ Tutorial
Spring 1
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


HPM300 Independent Study/ Tutorial
Spring
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


HPM300 Independent Study/ Tutorial
Spring 2
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


HPM300 Independent Study/ Tutorial
WinterSession
Department Members

Time and credit to be arranged.

An opportunity for independent study is offered for interested and qualified students or small groups of students. Arrangements must be made with individual faculty members and are limited by the amount of faculty time available. These programs are open to all students who wish to go beyond the content of regular courses.
Course Note: Completed independent study contract is required at the time of registration; maximum of 5 credits per independent study topic; pass/ fail only; signature of instructor required.

Course Evaluations


HPM350 Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required.

Course Evaluations


HPM350 Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM350 Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM350 Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM350 Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM350 Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM350 Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM400 Non-Resident Research
Fall 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/Fail only; maximum of 20 credits; signature of instructor required. (5.06)

Course Evaluations


HPM400 Non-Resident Research
Fall
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM400 Non-Resident Research
Fall 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM400 Non-Resident Research
Spring 1
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM400 Non-Resident Research
Spring
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM400 Non-Resident Research
Spring 2
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM400 Non-Resident Research
WinterSession
Department Members

Time and credit to be arranged.

For doctoral candidates who have passed their school-wide Oral Qualifying Examination and who are undertaking advanced work along the lines of fundamental or applied research in the department.
Course Note: Pass/fail only; maximum of 20 credits, signature of instructor required.

Course Evaluations


HPM510 Introduction to Management of Health Care Organizations
Summer 1
Dr. M. Roberts

2.5 credits
Lectures, case studies. Five 2-hour sessions each week.

This course provides an introduction to two of the major tasks confronting managers of health care organizations. Building on an introduction to organizational theory, the course focuses on the main problems of organizational strategy and the management of human resources. This course makes extensive use of case based classroom discussions, as well as selected conceptual readings. (rev. 10.06)


Course evaluations are an important method for feedback on the quality of course offerings. The submission of a course evaluation is a requirement for this course. Your grade for the course will be made available only after you have submitted responses to at least the first three questions of the on-line evaluation for this course.
Course Evaluations


HPM512 Medical Informatics