LTQ Orbitrap™

"Combining patented Orbitrap technology with the highly successful LTQ™ linear ion trap, Thermo Scientific's LTQ Orbitrap™ enables faster, more sensitive and more reliable detection and identification of compounds in complex mixtures. Its outstanding mass accuracy, mass resolution and reliable high sensitivity MSn performance make it a clear alternative to existing hybrid Time-of-Flight systems." 
-Thermo Scientific

To read more about this system, you can go the  Thermo Fisher web site to access the product brochure.

PicoView PV500    Nano ESI Source 
The PicoView® system is all about sensitivity. Spraying directly off of the column with PicoFrit® columns, a correctly tuned spray, and athe flexibility to control each element all work towards maximizing sensitivity. And because the PicoView system makes it so simple to increase your sensitivity, it helps to maximize your results.
Features:

• Magnetic Interlock Stage
• Advanced Spray Imaging
• High-resolution tip imaging
• Universal valve mount
• you can read additonal information and specifications at  The New Objective Web Site 

The TriVersa NanoMate is the latest in chip-based technology from Advion that combines the strengths of LC, fraction collection and chip-based infusion in one integrated system. It allows researchers to obtain more information from their complex samples than with LC/MS alone. 

Read more about this system at  The Advion TriVersa web site

Eksigent NanoLC-2D
This design boasts a fully automated 2-dimensional chromatography system ideal for whole proteome profiling, low abundance protein identification, and post translational modification.

The unit is built with a 10-port column switching valve, 2 binary gradient pumps and autosampler. The NanoLC-2D system does not only provide high-throughput proteomics, it is designed for flexibility. The system allows three modes of operation: 1D, 2D, or parallel separations.

Visit the  Eksigent web site for more information.

Surveyor LCQ Deca XP

The fully-integrated Surveyor LCQ Deca XP system combines the ruggedness of an orthogonal API source with the specificity of MS, creating the most sensitive quadrupole ion trap mass spectrometry available. Fully-automated MS capabilities and advanced Data Dependent experiment design features make analysis of low-abundance compounds in any matrix routine. Powerful Xcalibur software accelerates data analysis and simplifies the generation of results while providing a single platform to control LC/MS experiments. With cutting-edge hardware design, outstanding reliability and intelligent software, the LCQ Deca XP is the benchmark instrument for metabolism and proteomics applications.

Features

• The new orthogonal API source introduces enhanced sensitivity and ruggedness. 
• The ion sweep technology reduces chemical noise.
• The removable metal ion capillary tube provides vent-free maintenance.
• High stablity and ion transmission efficiency.
• Regulated helium flow for stable operation.
• Automated system calibration and optimization.

The Software features include :

• Xcalibur processing and instrument control software. 
• Full-scan mass spectra for sensitive analyses and spectra for rapid screening of unknown compounds.
• Selected Ion Monitoring for monitoring of selected ions for target compound analysis.
• ZoomScan, a high-resolution, narrow-range scan to resolve isotopic envelopes.
• TurboScan, an ultra-fast scan to improve signal-to-noise and sampling rates.
• Data Dependent features that trigger acquisition of MS spectra only when a compound of interest is detected.

In addition, the BioWorks 3.0 Software Suite provides the following functionalities :

• Expanded database and results management utilities.
• Rapid, first pass searches with MS data for peptide fingerprinting using Peptide Mapping.
• Automatic de novo peptide sequencing to analyze unique or novel proteins.
• Automatic generation of higher density data using Dynamic Exclusion.

The Sage-N Sorcerer 2 IDA
Sorcerer IDAs (integrated data appliances) provides efficient protein identification using shotgun proteomics, with increased accuracy and throughput, and advantageously reduced IT maintenance. The server version, the Sorcerer 2 IDA, is designed to support multiple research groups, such as in proteomics core facilities. It is for researchers whose throughput and sophistication needs outgrow their basic all-in-one PC proteomics software, while offering improved reliability and operating cost compared to cluster computers.

• High throughput 
• No IT maintenance 
• Plug and play setup 
• Simple operation 
• Multi-user, web-based access 
• Supports all major mass spec vendors 
• Search RAW files directly 
• Optimized for PTM searches 
• Automated false positive estimation 
• Data repository 

Copyright 2008 President and Fellows of Harvard College. All rights reserved. Created and maintained by HPR