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Scott Evans

Senior Research Scientist

Department of Biostatistics

651 Huntington Ave.
FXB-513
Boston, MA 02115
617.432.2998
evans@sdac.harvard.edu

Research

Scott Evans is a senior researcher and faculty member at Harvard University where he teaches “Clinical Trials”.  Dr. Evans is a Special Government Employee (SGE) of the FDA, serving on the Advisory Committee for CDRH and as a consultant for CDER.  He serves on numerous Data Monitoring Committees (DMCs) including as Chair of the Adolescent Medicine Trials Network (ATN).

Dr. Evans is the Principal Investigator (PI) of the Statistical and Data Management Center of the Neurologic AIDS Research Consortium (NARC, funded by NIH/NINDS) and the Oral HIV/AIDS Research Alliance (OHARA, funded by NIH/NIDCR).  Dr. Evans is the Deputy Scientific Director of the Program for Quantitative Sciences in Medicine in the Department of Biostatistics at Harvard University.  Dr. Evans was recently awarded the "Robert Zackin Distinguished Collaborative Statistician Award" for significant statistical contributions to HIV research, received a Recognition Award for contributions of statistical expertise from the Harvard School of Public Health, received a Distinguished Service Award from the Council of Chapters of the American Statistical Association, received a Meritorious Outstanding Contributor Award from the Biopharmaceutical Applied Statistics Symposium (BASS), and was inducted as a faculty member into Mu Sigma Rho, the National Honorary Society for Statistics.

Dr. Evans is member of the Human Subjects Committee (Institutional Review Board) of the Harvard School of Public Health and is a member of several Scientific Advisory Boards including "Novel Therapeutics in HIV-Associated Cognitive Disorders" (Johns Hopkins University), the "HIV Neurobehavioral Research Center" (UCSD), and the PML Advisory Board (Genentech).  He has served an expert witness for the Commonwealth of Massachusetts and serves on the Editorial Board for several journals.  Dr. Evans has taught short courses at the Joint Statistical Meetings (JSM), BASS, the annual meeting of the Society for Clinical Trials (SCT), the FDA-Industry Workshop in Statistics, the Graybill Conference on Biopharmaceutical Statistics, the American Neurological Association, Beth Israel Deaconess Medical Center, and the Pharmaceutical Education Research Institute (PERI).

Dr. Evans is the Past-President of the Boston Chapter of the American Statistical Association (ASA), is the Past-Chair of the Statistics in Sports Section of ASA, is the Chair of the Teaching Statistics in the Health Sciences Section of ASA, is on the Board of Directors for Mu Sigma Rho, was appointed Chair of the Development Committee and the Committee for Statisticians in Defense and National Security of ASA, is Co-Chair of the New England Symposium on Statistics in Sports, will Co-Chair the New England Statistics Symposium (NESS), and served on the Program Committee for the Society for Clinical Trials (SCT), ENAR, the Harvard-Schering-Plough Workshop, and the Graybill Conference on Biopharmaceutical Statistics.

Publications

  1. Evans SR, “Benefit:Risk Evaluation in Clinical Trials”, Drug Information Journal, 42:3:221, 2008.
  2. Evans SR, Glickman “New England Symposium on Statistics in Sports”, Journal of Quantitative Analysis in Sports, (in press), 2008.
  3. Evans SR, Li L, Wei LJ, “Data Monitoring in Clinical Trials Using Prediction”, Drug Information Journal, 41:733-742, 2007.
  4. Evans SR, Fichtenbaum C, Aberg J, “Comparison of Direct and Indirect Measurement of LDL in HIV Infected Individuals: ACTG 5087”, HIV Clinical Trials, 8:1:45-52, 2007.
  5. Evans SR, “When and How Can Endpoints Be Changed after Initiation of a Randomized Clinical Trial?” Public Library of Science (PLoS) Clinical Trials 2(4): e18. doi:10.1371/journal.pctr.0020018, 2007.
  6. Evans SR, Simpson D, Kitch DW, King A, Clifford DB, Cohen BA, McArthur JC, “A Randomized Trial Evaluating Prosaptide for HIV-Associated Sensory Neuropathies: Use of an Electronic Diary to Record Neuropathic Pain”, PLoS ONE, 2(7): e551. doi:10.1371/journal.pone.0000551, 2007.
  7. Evans SR, Yeh T, Sacktor N, Clifford DB, Simpson D, Miller EN, Ellis RJ, Valcour V, Marra CM, Millar L, Shiffitto G, “Selegiline Transdermal System (STS) for HIV-Associated Neurocognitive Impairment: Open-label Report of ACTG 5090”, HIV Clinical Trials, 8:6:437-446, 2007.
  8. Evans SR, Wang R, Haija R, Zhang J, Rajicic N, Xanthakis V, Peeples L, Anderson J, Sinha S, “Evaluation of Distance Learning in an Introduction to Biostatistics Course”, Statistical Education Research Journal, 6(2):59-77, 2007.
  9. Clifford DB, Mitike MT, Mekonnen Y, Zhang J, Zenebe G, Melaku Z, Zewde A,  Gessesse N,  Wolday D, Messele T, Teshome M, Evans SR, “Neurological Evaluation of Untreated HIV Infected Adults in Ethiopia”, Journal of NeuroVirology, 13:1-6, 2007.
  10. Evans SR, Li L, “A Comparison of Goodness of Fit Tests for the Logistic GEE Model”, Statistics in Medicine, 24:1245-1261, 2005.
  11. Clifford DB, Evans SR, Yang Y, Acosta E, Goodkin K, Tashima K, Simpson D, Dorfman D, Ribaudo H, Gulick RM, “Impact of Efavirenz on Neuropsychological Performance and Symptoms in HIV-Infected Individuals”, Annals of Internal Medicine, 143:714-721, 2005.
  12. Ellis R, Evans SR, Clifford D, Moo L, McArthur J, Collier A, Benson C, Bosch R, Simpson D, Yiannoutsos C, Yang Y, Robertson K, “Clinical Validation of the Neuroscreen”, Journal of NeuroVirology, 11:6:503-511, 2005.
  13. Evans SR, Hosmer DW, “Goodness of Fit Tests for Mixed Effects Logistic Models”, Communications in Statistics: Theory and Methods, 33:5:1139-1155, 2004.
  14. Evans SR, Hosmer DW, “Goodness of Fit Tests for Logistic GEE Models: Simulation Results”, Communications in Statistics: Simulation and Computation, 33:1:247-258, 2004.
  15. Evans SR, Testa MA, Cooley TP, Krown SE, Paredes J, Von Roenn JH, “A Phase II Evaluation of Low-Dose Oral Etoposide for the Treatment of Relapsed or Progressed AIDS-Related Kaposi's Sarcoma: An ACTG Clinical Study”, Journal of Clinical Oncology, 20:15:3236-3241, 2002.