Dr. Shapiro is an Associate Professor in Medicine at Harvard Medical School and Harvard School of Public Health. His primary research interests are in the prevention of mother-to-child HIV transmission (PMTCT) and the reduction of morbidity and mortality among infants born to HIV-infected women. Since 1999, Dr. Shapiro has studied infant outcomes and peripartum PMTCT strategies among 1200 mothers and infants in the Mashi Study in Botswana. He is the principal investigator of the Mma Bana Study, which is evaluating virologic efficacy and HIV transmission rates among 730 women receiving 3 different antiretroviral combinations during pregnancy, delivery, and breastfeeding. In 2010-2011, Dr. Shapiro will be initiating a new NIH-funded clinical trial to reduce infant mortality among HIV-exposed infants.
Dr. Shapiro is also the principal investigator for a study of birth outcomes in Botswana that will evaluate more than 25,000 deliveries among HIV-infected and HIV-uninfected women. He is also a co-investigator for a pilot implementation study to provide male infant circumcision services in Botswana. Dr. Shapiro works closely with the Botswana PMTCT Programme, and is a member of the PMTCT Advisory Panel for the World Health Organization.
Dr. Shapiro is an Associate Director for Education at the Harvard Initiative for Global Health. In this capacity, he helps to mentor Infectious Disease fellows, residents, and students who are interested in research projects related to international HIV. Dr. Shapiro has helped to establish a Clinical Care and Research Fellowship at the Scottish Livingstone Hospital in Molepolole, Botswana to support fellows and junior faculty starting careers in international HIV.