Publications

Weetman D., Mitchell S.N., Wilding C. S., Birks D. P., Yawson A. E., Essandoh J., Mawejje H. D., Djogbenou L. S., Steen K., Rippon E. J., Clarkson C. S., Field S. G., Rigden D. J., Donnelly M. J. 2015. Contemporary evolution of resistance at the major insecticide target site gene Ace-1 by mutation and copy number variation in the malaria mosquito Anopheles gambiae. Mol Ecol. Apr 11. doi: 10.1111/mec.13197.

Mitchell* S.N., Kakani* E. G, South* A, Howell P. I, Waterhouse R. M, Catteruccia F. 2015 Evolution of sexual traits influencing vectorial capacity in anopheline mosquitoes. Science 347(6225):985-8. doi: 10.1126/science.1259435. *Joint First Authors

16 Genomes Consortium., 2014. Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes, Science 347(6217):1258522. doi: 10.1126/science.1258522.

Fontaine M. C., Pease J. B., Steele A., Waterhouse R. M., Neafsey D. E., Sharakhov I. V., Jiang X., Hall A. B., Catteruccia F., Kakani E., Mitchell S.N., Wu Y., Smith H. A., Love R. R., Lawniczak M. K.,. Slotman M. A, Emrich S. J., Hahn M. W., and Besansky N. J., 2014 Extensive introgression in a malaria vector species complex revealed by phylogenomics , Science 347(6217):1258524. doi: 10.1126/science.1258524

Gabrieli* P., Kakani* E.G., Mitchell* S.N., Mameli E., Want E.J., Mariezcurrena Anton A., Serrao A., Baldini F., Catteruccia F., 2014. Sexual transfer of the steroid hormone 20E induces the postmating switch in Anopheles gambiae. Proc Natl Acad Sci U S A. 111(46):16353-8. doi: 10.1073/pnas.1410488111. *Joint First Authors

Shaw W.R., Teodori, E., Mitchell, S.N., Baldini, F., Gabrieli P., Rogers, D.W., Catteruccia, F., 2014. Mating activates the heme peroxidase HPX15 in the sperm storage organ to ensure fertility in Anopheles gambiae. Proc Natl Acad Sci U S A 111(16):5854-9, doi:10.1073/pnas.1401715111.

Mitchell* S.N., Rigden D. J., Dowd A.J., Lu F., Wilding C.S., Weetman D., Dadzie S., Jenkins A. M., Regna K., Boko P; Djogbenou L., Muskavitch M. A., Ranson H., Paine M J., Mayans O., Donnelly M. J., 2014.  Metabolic and Target-Site Mechanisms Combine to Confer Strong DDT Resistance in Anopheles gambiae. PloS One 9(3):e92662

Kwiatkowska RM, Platt N, Poupardin R, Irving H, Dabire RK, Mitchell S, Jones CM, Diabaté A, Ranson H, Wondji CS., 2013. Dissecting the mechanisms responsible for the multiple insecticide resistance phenotype in Anopheles gambiae s.s., M form, from Vallée du Kou, Burkina Faso.  Gene. 519(1):98-106

Daborn P.J., Lumb C., Harrop T., Blasetti A., Morin S., Mitchell S.N., Donnelly M.J., Müller P., Batterham P., 2012.  Using Drosophila melanogaster to validate metabolism-based insecticide resistances from insect pests. Insect Biochem Mol Biol. 42(12):918-24.

Mitchell* S.N., Stevenson B., Muller P., Wilding C., Yawson A., Field S., Hemingway J., Paine M., Ranson H., Donnelly M., 2011. Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana. Proc Natl Acad Sci U S A. 109 (16): 6147-615.

Lynd A., Weetman D., Barbosa S., Egyir-Yawson A., Mitchell S., Pinto J., Hastings I., Donnelly M.J., 2010. Field, genetic and modelling approaches show strong positive selection acting upon an insecticide resistance mutation in Anopheles gambiae s.s. Mol. Biol. Evol. 27(5):1117-25
Muller, P., Warr, E., Stevenson, B.J., Pignatelli, P.M., Morgan, J.C., Steven, A., Yawson, A.E., Mitchell, S. N., Ranson, H., Hemingway, J., Paine, M.J.I., Donnelly, M.J., 2008. Field-caught permethrin resistant Anopheles gambiae over-express CYP6P3, a P450 that metabolises pyrethroids. PLoS Genet. 4 (11): e1000286

Muller, P., Warr, E., Stevenson, B.J., Pignatelli, P.M., Morgan, J.C., Steven, A., Yawson, A.E., Mitchell, S.N., Ranson, H., Hemingway, J., Paine, M.J.I., Donnelly, M.J., 2008. Field-caught permethrin resistant Anopheles gambiae over-express CYP6P3, a P450 that metabolises pyrethroids. PLoS Genetics 4 (11): e1000286