Country: Botswana

Health Governance Index and Regional Harmonization in Africa

The purpose of this project is researching and designing methodology, contributors, presentations and written materials for a health governance index and report, modeled after the Africa Competitiveness Report series produced by the World Economic Forum, but with health governance as…

Read More

AIDS Action: Priorities for Southern Africa

With more than 60% of the world’s population living with AIDS, sub-Saharan Africa is the hardest hit region of the AIDS epidemic. Many of these African countries have been mobilizing efforts to create effective national and regional responses for the…

Read More

HAART to Prevent HIV Transmission to Infants in Botswana

Highly active antiretroviral therapy (HAART) is rapidly becoming available in the developing world, but the safety and efficacy of different HAART regimens for preventing mother-to-child HIV transmission in a breastfeeding population has not been determined. A treatment, Trizivir, may be…

Read More

Partners in Prevention Study for Botswana (Preparedness Phase of Phase III Randomized Placebo-Controled Trial of HSV-2 Suppression to Prevent HIV Transmission among HIV-Discordant Couples)

The primary objective of this study is to measure the efficacy of twice daily acyclovir suppressive therapy in preventing HIV transmission among HIV-discordant couples, in which the HIV-infected partner is HSV-2-seropositive and has a CD4 cell count of 250 cells/mm3…

Read More

International Training in AIDS-Related Epidemiology

Faculty associated with the university-wide Harvard AIDS Institute (HAI) and especially the Harvard School of Public Health (HSPH) have developed strong programs for AIDS research training in collaboration with 6 developing countries: Senegal, Tanzania, Botswana, Thailand, Nigeria, and China. The…

Read More

Alcohol Use and the Risk of HIV-1 Infection in Botswana

The World Health Organization has estimated that more than 36 million adults and children have been infected with HIV-1 worldwide. In sub-Saharan Africa, the AIDS pandemic has been most severe, with more that 25 million individuals living with HIV-1. In…

Read More

Health of HIV-Infected Mothers after pMTCT, Botswana

Maternal health concerns are an important but understudied aspect of programs designed to prevent mother-to-child HIV-1 transmission in the developing world. Two of the most important and urgent questions regarding maternal health in this context are whether breastfeeding by HIV-infected…

Read More

Early and Acute HIV-1 Subtype C Infection in Botswana

HIV-1 subtype C is the dominant HIV-1 subtype C in the AIDS epidemic. Botswana, a country in southern Africa with an estimated HIV prevalence of about 35-40%, provides the epidemiologic and laboratory infrastructure for this study. The purpose of this…

Read More

Botswana HIV Vaccine Trials Unit-Core Funds

An HIV Vaccine Trials Unit (HVTU) has been established at the Botswana-Harvard AIDS Institute Partnership site in Gaborone, Botswana. Its ongoing operation will allow HIV Vaccine Trials Network (HVTN) protocols and related research to be conducted in Botswana.

Read More

Cost-Effectiveness of HAART for HIV and AIDS in Botswana

A particular sub-Saharan African country, Botswana, has experienced a disproportionate burden of the HIV/AIDS epidemic. Botswana currently has the world’s highest reported prevalence rates with an estimated 37.4% (2003) of the overall population infected with HIV-1. While Anti-retroviral (ART) therapy…

Read More