A Trial of Zinc and Micronutrients in Tanzanian Children


Principal Investigator:
Christopher Duggan, Associate Professor in the Department of Nutrition



Dates of Research:
August 10, 2006 — June 30, 2012


This study examines the efficacy of zinc or multiple micronutrient supplementation in reducing the risk of infectious diseases and growth faltering among 2,400 infants and young children in Tanzania. Infants born to HIV-negative women will be recruited and randomly assigned to either zinc, micronutrients (Vitamins C, E, B1, B2, niacin, B6, folate, and B12) plus zinc, micronutrients without zinc, or a placebo given daily. Children will be followed at monthly clinic visits from age 6 weeks to 18 months. The primary outcomes measure will be the incidence of diarrhea and respiratory tract infections, and secondary will be weight and length gain.

Website: http://clinicaltrials.gov/ct2/show/NCT00421668