David Christiani, Professor of Occupational Medicine and Epidemiology
Department of Epidemiology
Dates of Research:
September 23, 2002 — July 31, 2008
This project is an environmental molecular epidemiologic investigation of groundwater arsenic exposure, genetic polymorphisms and skin lesions in Bangladesh. Bangladesh has experienced an epidemic of arsenic intoxication because tube wells have been drilled into alluvial deposits high in naturally occurring inorganic arsenic. This case-control and repeated measures investigation aims to clarify exposure-responses and modification of adverse health effects of exposure by heritable (genetic) and lifestyle (e.g. diet) factors.