Genetic Diversity of the Vaccine Candidates, AMA-1 and MSP-1, from Clinical Isolates of Plasmodium Falciparum and Plasmodium Vivax in Sri Lanka

Country/Countries:

Principal Investigator:
Dyann Wirth, Chair, Department of Immunology and Infectious Diseases and Richard Pearson Strong Professor of Infectious Diseases

Department:
Department of Immunology and Infectious Diseases

Dates of Research:
July 1, 2004 — June 30, 2006

Description:

Malaria is considered to be one of the most devastating global health problems due to the high morbidity and mortality it causes in the tropical parts of the world where it is endemic. This study will assess the genetic diversity among parasite populations, which will have significant relevance for better understanding its biology, for the development of strategies of disease control and to make valid estimations with regard to its origin.