David Christiani, Elkan Blout Professor of Environmental Genetics
Dates of Research:
September 1, 2006 — July 30, 2011
The objective of this study is to determine the rate of loss in lung function among cotton dust-exposed workers at various levels of dust exposure and evaluating the relationship of exposure to gram-negative bacterial endotoxin and acute and chronic lung disease. The study will also examine the effects of polymorphism in genes responsible for endotoxin responses in humans and the observed lung function changes.