Measurement Errors in Cancer Epidemiology


Principal Investigator:
Donna Spiegelman, Professor of Epidemiologic Methods


Dates of Research:
September 27, 2006 — August 31, 2010


Exposure measurement errors in cancer epidemiology pose special methodolologic challenges. For example, nutritional exposures form the basis for many etiologic hypotheses concerning cancer. However, nutrient intake is difficult to measure precisely. Other important examples considered in this study include genomic risk factors and environmental exposures. To accomplish this requires both a main study where disease and the surrogate exposure are measured and validation data to determine the extent of the corrections for measurement error and misclassification.