United Republic Of Tanzania
Department of Global Health and Population
Dates of Research:
October 6, 2004 — December 31, 2008
This project will develop a cohort of high-risk women, including women currently enrolled in the Moshi Sexually Transmitted Diseases (STDs) Prevention Pilot (MSPP) study, and participate in activities to prepare for implementation of phase I/IIB safety and effectiveness studies of candidate vaginal microbicides. The primary objectives of the study are: 1) to determine the HIV incidence and evaluation risk factors for seroconversion among high-risk women in Moshi, Tanzania; 2) to estimate retention in the cohort and identify efficient retention efforts that will ensure high retention in future microbicide trials; and 3) to estimate the incidence of sexual transmitted infections.