Projects

The Role of Non-Governmental Health Care: A Study of its Scope and Potential With a Focus on Policies to Promote its Contribution to Improved Health

Non-government providers are increasingly the dominant source of personal health care of public health significance, including acute care for many important communicable diseases like tuberculosis, malaria, HIV/AIDS, diarrheas, and respiratory infections. Non-governmental providers are also often the main source of…

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Dose Response Modeling in Epidemiologic Cohort Studies

This proposal builds on current work applying semiparametric statistical methods to model nonlinear exposure-response curves with smooth functions of exposure in occupational cohort studies (R01CA81345). In the course of adapting penalized splines for survival analysis, there have been two issues…

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Anti-HIV Therapy in Senegal, West Africa

This project aims to create an infrastructure and training model that will support the national ARV program in Senegal and provide important new data on treatment regimens applicable to the African setting. The specific goals are to: (1) Conduct clinical…

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Determinants of Drug Resistant Malaria in Nigeria

Malaria is Africa’s largest and most persistent public health problem. More than 1 to 2 million African children under the age of 5 die of malaria every year, including 300,000 who are Nigerian. The rapid spread of a strain of…

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Partners in Prevention Study for Botswana (Preparedness Phase of Phase III Randomized Placebo-Controled Trial of HSV-2 Suppression to Prevent HIV Transmission among HIV-Discordant Couples)

The primary objective of this study is to measure the efficacy of twice daily acyclovir suppressive therapy in preventing HIV transmission among HIV-discordant couples, in which the HIV-infected partner is HSV-2-seropositive and has a CD4 cell count of 250 cells/mm3…

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International Neurological Study

This project provides statistical support for the 192-week clinical trial entitled, “”Enhanced Nursing Support to Improve Self-Management and Outcomes of ART.”” The trial is designed to implement and evaluate an intervention delivered by nurses from a central site that is…

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Ethics in Health Research in China: Capacity Development

China has recently become a major partner with American Universities, institutes, and companies in conducting multiple projects of collaborative health research. As this partnership continues to grow, the opportunity now exists to work with Chinese colleagues in building the foundations…

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