Publications

Articles

Wong YL, Sampson S, Germishuizen WA, Goonesekera S, Caponetti G, Sadoff J, Bloom BR, Edwards D.  Drying a tuberculosis vaccine without freezing.  Proc Natl Acad Sci USA. 2007 Feb 20;104(8):2591-5.

Khare S, Hondalus MK, Nunes J, Bloom BR, Garry Adams L.  Mycobacterium bovis DeltaleuD auxotroph-induced protective immunity against tissue colonization, burden and distribution in cattle intranasally challenged with Mycobacterium bovis Ravenel S.  Vaccin.e 2007 Feb 26;25(10):1743-55.

Tan BH, Meinken C, Bastian M, Bruns H, Legaspi A, Ochoa MT, Krutzik SR, Bloom BR, Ganz T, Modlin RL, Stenger S. Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens.  J Immunol. 2006 Aug 1;177(3):1864-71.

Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik S, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response.  Science. 2006; 311(5768): 1770-3.

Bloom BR, Salomon JA. Enlightened self-interest and the control of tuberculosis.  N Engl J Med. 2005; 353(10):1057-9.

Bloom BR.  Public Health in Transition.  Sci Am. 2005; 293(3): 92-9.

Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ.  Mutually-dependent secretion of proteins required for mycobacterial virulence.  Proc Natl Acad Sci USA.  2005; 102(30):10676-81.

Rengarajan J, Bloom BR, Rubin EJ.  Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages.  Proc Natl Acad Sci USA. 2005; 102(23): 8327-32.

Krutzik SR, Tan B, Li H, Ochoa MT, Liu PT, Sharfstein SE, Graeber TG, Sieling PA, Liu YJ, Rea TH, Bloom BR, Modlin RL.  TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells.  Nat Med. 2005; 11(6):653-60.

Pan H, Yan BS, Rojas M, Shebzukhov YV, Zhou H, Kobzik L, Higgins DE, Daly MJ, Bloom BR, Kramnik I.  Ipr1 gene mediates innate immunity to tuberculosis.  Nature. 2005; 434(7034):767-72.

Rengarajan J, Sassetti CM, Naroditskaya V, Sloutsky A, Bloom BR, Rubin EJ.  The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria.  Mol Microbiol. 2004; 53(1):275-82.

Fortune SM, Solache A, Jaeger A, Hill PJ, Belisle JT, Bloom BR, Rubin EJ, Ernst JD. Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms. J Immunol. 2004; 15;172(10):6272-80.

Sampson SL, Dascher CC, Sambandamurthy VK, Russell RG, Jacobs WR Jr, Bloom BR, Hondalus MK.  Protection elicited by a double leucine and pantothenate auxotroph of Mycobacterium tuberculosis in guinea pigs.  Infect Immun. 2004; 72(5):3031-7.

Jain S, Bloom BR, Hondalus MK. Deletion of vapA encoding Virulence Associated Protein A attenuates the intracellular actinomycete Rhodococcus equi.  Mol Microbiol. 2003; 50(1):115-28.

Bleharski JR, Li H, Meinken C, Graeber TG, Ochoa MT, Yamamura M, Burdick A, Sarno EN, Wagner M, Rollinghoff M, Rea TH, Colonna M, Stenger S, Bloom BR, Eisenberg D, Modlin RL. Use of genetic profiling in leprosy to discriminate clinical forms of the disease.  Science. 2003; 301(5639):1527-30.

Bloom BR. Lessons from SARS. Science. 2003 May 2;300(5620):701.

Bloom BR. Tuberculosis–the global view. N Engl J Med. 2002 May 9;346(19):1434-5.

Bloom BR and Trach DD. Genetics and developing countries. BMJ. 2001. Apr 28;322(7293):1006-7.

Michaud CM, Murray CJ, Bloom BR. Burden of disease–implications for future research. JAMA. 2001 Feb 7;285(5):535-9.

Bloom BR. Public-health priorities in the industrialised world. Lancet. 2000 Dec;356 Suppl:s50.

Bloom BR. On the particularity of pathogens. Nature. 2000 Aug 17;406(6797):760-1.

Kramnik I, Dietrich WF, Demant P, Bloom BR. Genetic control of resistance to experimental infection with virulent Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8560-5.

Bloom BR. The future of public health. Nature. 1999 Dec 2;402(6761 Suppl):C63-4.

Bloom BR. Patient power–the wrong rights. We need rights to prevention, not just payments. Newsweek. 1999 Oct 11;134(15):92.

Bloom BR, McKinney JD. The death and resurrection of tuberculosis. Nat Med. 1999 Aug;5(8):872-4.

Bloom BR. Ethical issues in AIDS vaccine development. AIDS Patient Care STDS. 1999 May;13(5):273-80.

Howson CP, Fineberg HV, Bloom BR. The pursuit of global health: the relevance of engagement for developed countries. Lancet. 1998 Feb 21;351(9102):586-90.

Books

Bloom BR, Lambert PH. The Vaccine Book. Academic Press, 436 pp, 2003.

Committee on Science and Technology for Countering Terrorism. Making the Nation Safer: The Role of Science and Technology in Countering Terrorism. The National Academies Press, 2002.

Lederberg, J. (Editor-in-Chief), Alexander M, Bloom BR, Hopwood D, Hull R, Iglewiski BH, Laskin AI, Oliver SG, Schaechter M and Sommers WC. (Associate Editors), Encyclopedia of Microbiology, Academic Press, 2000

Bloom BR, ed. Tuberculosis: Pathogenesis, Protection and Control. ASM Press, 637 pp.; 1994.

Bloom BR and Cerami A, eds.  Biomedical Science and the Third World: Under the Volcano.  L.W. Frohlich Award Conference, New York Academy of Sciences, Ann. N.Y. Acad. Sci. vol.569, 334pp; 1989.

Bloom BR and David JR, eds. “In vitro Methods in Cell-Mediated and Tumor Immunity” Academic Press. 1976.

 

Bloom BR and Glade P, eds.  In vitro methods in cell-mediated immunity.  Academic Press, pp. 606. 1971.