Publications

Recent Publications:

  1. PMID:24285487 Moon, S, Szlezák, NA, Michaud, CM, Jamison, DT, Keusch, GT, Clark, WC, Bloom, BR. The Global Health System: Lessons for a Stronger Institutional Framework. PLoS Medicine 2010; 7:e1000193
  2. Goldstone, RM, Goonesekera, SD, Bloom, BR, Sampson, SL. The transcriptional regulator Rv0485 modulates the expression of a pe and ppe gene pair and is required for Mycobacterium tuberculosis virulence. Infect Immun 2009; 77:4654-67.
  3. Szlezák, NA, Bloom, BR, Jamison, DT, Keusch, GT, Michaud, CM, Moon, S, Clark, WC. The Global Health System: Actors, Norms and Expectations in Transition. PLoS Medicine 2010; 7:e1000183.
  4. Bloom, BR Support for global health.  Science 2010 328:791.
  5. Bloom, BR, Woods W. “Public Private Partnership Models” WHO Global Strategy for Women and Children’s Health: Investing in our Common Future-Version 2, http://www.who.int/pmnch/activities/jointactionplan/100922_2_investing.pdf, 2010.
  6. Bloom, BR. WHO needs change. Nature 2011; 473:143-5.
  7. Farmer, P, Almazor, CP, Bahnsen, ET, Barry, D, Bazile J, Bloom BR, Bose, N, Brewer, T, Calderwood, SB, Clemens, JD, Cravioto, A, Eustache, E, Jerome, G, Gupta, N, Harris, JB, Hiatt, HH, Holstein, C, Hotez, PJ, Ivers, LC, Kerry, VB, Koenig, SP, LaRocque, RC, Leandre, F. Lambert, W, Lyon, E, Mekalanos, JJ, Mukherjee, JS, Oswald, C, Pape, JW, Prosper, AG, Rabinovich, R, Raymonville, M, Rejouit, JR, Ronan, LJ, Rosenberg, ML, Ryan, ET, Sachs, JD, Sack, DA, Surena, C, Suri, AA, Ternier, R, Waldor, MK, Walton, D, and Weigel, JL.   Meeting Cholera’s Challenge to Haiti and the World: A Joint Statement on Cholera Prevention and Care.   PLoS Neglected Tropical Disease 2011; 5:e1145.
  8. Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, Hollis BW, Hewison M, Adams JS, Steinmeyer A, Zügel U, Cheng G, Jo EK, Bloom BR, Modlin RL. Vitamin D Is Required for IFN-{gamma}-Mediated Antimicrobial Activity of Human Macrophages. Sci Transl Med. 2011; 3:104ra102.
  9. Lipsitch M, Plotkin JB, Simonsen L, Bloom B. Evolution, safety, and highly pathogenic influenza viruses. 2012 Jun 22; 336:1529-31.
  10. Ganmaa D, Giovannucci E, Bloom BR, Fawzi W, Burr W, Batbaatar D, Sumberzul N, Holick MF, Willett WC. Vitamin D, tuberculin skin test conversion, and latent tuberculosis in Mongolian school-age children: a randomized, double-blind, placebo-controlled feasibility trial. Am J Clin Nutr. 2012 Aug; 96:391-6.
  11. Lipsitch M, Bloom BR. Rethinking biosafety in research on potential pandemic pathogens. MBio 2012 Oct; 3(5). Doi:pii: e00360-12.
  12. Laxminarayan R, Arrow K, Jamison D, Bloom BR. Public health. From financing to fevers: lessons of an antimalarial subsidy program. Science. 2012 Nov 2: 338:615-6.
  13. Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL. Type I Interferon Suppresses Type II Interferon-Triggered Human Anti-Mycobacterial Responses. 2013 Feb 28. [Epub ahead of print].
  14. Bishai W, Sullivan Z, Bloom BR, Andersen P. Bettering BCG: a tough task for a TB vaccine? Nature Medicine. 2013 Apr;19(4):410-1.
  15. Modlin RL, Bloom BR. TB or not TB: that is no longer the question. Science Translational Medicine. 2013 Nov 27;5(213):213.
  16. Bloom BR, Marcuse E, Mnookin S. Addressing vaccine hesitancy. Science. 2014 Apr 25;322(6182):339.
  17. Paniz Mondolfi AE, Bloom BR. Jacinto Convit (1913-2014). Am J Trop Med Hyg. 2014 Aug;91(2):435-6.
  18. Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, Bloom BR, Modlin RL. IL-32 is a molecular marker of a host defense network in human tuberculosis. Sci Transl Med. 2014 Aug 20;6(250):250ra114.
  19. Modlin RL, Bloom BR.TB or not TB: that is no longer the question. Sci Transl Med. 2013 Nov 27;5(213):213sr6. doi: 10.1126/scitranslmed.3007402. Review.
  20. Mechanisms of Defense against Intracellular Pathogens Mediated by Human Macrophages.
    Bloom BR, Modlin RL. Microbiol Spectr. 2016 Jun;4(3). doi: 10.1128/microbiolspec.MCHD-0006-2015. PMID: 27337485
  21. Rethinking how to address the world’s largest infectious killer in the world’s largest country.
    Bloom BR. J Public Health Policy. 2016 May 6. doi: 10.1057/jphp.2016.16. [Epub ahead of print]
    PMID: 27153154
  22. Back to the future: Rethinking global control of tuberculosis.
    Bloom BR, Atun R. Sci Transl Med. 2016 Mar 9;8(329):329ps7. doi: 10.1126/scitranslmed.aaf2944. Review. PMID: 26962154
  23. Lipoarabinomannan-Responsive Polycytotoxic T Cells Are Associated with Protection in Human Tuberculosis. Busch M, Herzmann C, Kallert S, Zimmermann A, Höfer C, Mayer D, Zenk SF, Muche R, Lange C, Bloom BR, Modlin RL, Stenger S; TBornotTB Network. Am J Respir Crit Care Med. 2016 Aug 1;194(3):345-55. doi: 10.1164/rccm.201509-1746OC.
  24. IL-32 is a molecular marker of a host defense network in human tuberculosis. Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, Bloom BR, Modlin RL. Sci Transl Med. 2014 Aug 20;6(250):250ra114. doi: 10.1126/scitranslmed.3009546. PMID: 25143364
  25. Addressing vaccine hesitancy. Bloom BR, Marcuse E, Mnookin S. Science. 2014 Apr 25;344(6182):339. doi: 10.1126/science.1254834. No abstract available. PMID: 24763557 PMID: 24285487
  26. TB or not TB: that is no longer the question. Modlin RL, Bloom BR. Sci Transl Med. 2013 Nov 27;5(213):213sr6. doi: 10.1126/scitranslmed.3007402. Review.
  27. Moon, S, Szlezák, NA, Michaud, CM, Jamison, DT, Keusch, GT, Clark, WC, Bloom, BR. The Global Health System: Lessons for a Stronger Institutional Framework. PLoS Medicine 2010; 7:e1000193
  28. Goldstone, RM, Goonesekera, SD, Bloom, BR, Sampson, SL. The transcriptional regulator Rv0485 modulates the expression of a pe and ppe gene pair and is required for Mycobacterium tuberculosis virulence. Infect Immun 2009; 77:4654-67.
  29. Szlezák, NA, Bloom, BR, Jamison, DT, Keusch, GT, Michaud, CM, Moon, S, Clark, WC. The Global Health System: Actors, Norms and Expectations in Transition. PLoS Medicine 2010; 7:e1000183.
  30. Bloom, BR Support for global health.  Science 2010 328:791.
  31. Bloom, BR, Woods W. “Public Private Partnership Models” WHO Global Strategy for Women and Children’s Health: Investing in our Common Future-Version 2, http://www.who.int/pmnch/activities/jointactionplan/100922_2_investing.pdf, 2010.
  32. Bloom, BR. WHO needs change. Nature 2011; 473:143-5.
  33. Farmer, P, Almazor, CP, Bahnsen, ET, Barry, D, Bazile J, Bloom BR, Bose, N, Brewer, T, Calderwood, SB, Clemens, JD, Cravioto, A, Eustache, E, Jerome, G, Gupta, N, Harris, JB, Hiatt, HH, Holstein, C, Hotez, PJ, Ivers, LC, Kerry, VB, Koenig, SP, LaRocque, RC, Leandre, F. Lambert, W, Lyon, E, Mekalanos, JJ, Mukherjee, JS, Oswald, C, Pape, JW, Prosper, AG, Rabinovich, R, Raymonville, M, Rejouit, JR, Ronan, LJ, Rosenberg, ML, Ryan, ET, Sachs, JD, Sack, DA, Surena, C, Suri, AA, Ternier, R, Waldor, MK, Walton, D, and Weigel, JL.   Meeting Cholera’s Challenge to Haiti and the World: A Joint Statement on Cholera Prevention and Care.   PLoS Neglected Tropical Disease 2011; 5:e1145.
  34. Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, Hollis BW, Hewison M, Adams JS, Steinmeyer A, Zügel U, Cheng G, Jo EK, Bloom BR, Modlin RL. Vitamin D Is Required for IFN-{gamma}-Mediated Antimicrobial Activity of Human Macrophages. Sci Transl Med. 2011; 3:104ra102.
  35. Lipsitch M, Plotkin JB, Simonsen L, Bloom B. Evolution, safety, and highly pathogenic influenza viruses. Science. 2012 Jun 22; 336:1529-31.
  36. Ganmaa D, Giovannucci E, Bloom BR, Fawzi W, Burr W, Batbaatar D, Sumberzul N, Holick MF, Willett WC. Vitamin D, tuberculin skin test conversion, and latent tuberculosis in Mongolian school-age children: a randomized, double-blind, placebo-controlled feasibility trial. Am J Clin Nutr. 2012 Aug; 96:391-6.
  37. Lipsitch M, Bloom BR. Rethinking biosafety in research on potential pandemic pathogens. MBio 2012 Oct; 3(5). Doi:pii: e00360-12.
  38. Laxminarayan R, Arrow K, Jamison D, Bloom BR. Public health. From financing to fevers: lessons of an antimalarial subsidy program. Science. 2012 Nov 2: 338:615-6.
  39. Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL. Type I Interferon Suppresses Type II Interferon-Triggered Human Anti-Mycobacterial Responses. Science. 2013 Feb 28. [Epub ahead of print].
  40. Bishai W, Sullivan Z, Bloom BR, Andersen P. Bettering BCG: a tough task for a TB vaccine? Nature Medicine. 2013 Apr;19(4):410-1.
  41. Modlin RL, Bloom BR. TB or not TB: that is no longer the question. Science Translational Medicine. 2013 Nov 27;5(213):213.
  42. Bloom BR, Marcuse E, Mnookin S. Addressing vaccine hesitancy. Science. 2014 Apr 25;322(6182):339.
  43. Paniz Mondolfi AE, Bloom BR. Dr. Jacinto Convit (1913-2014). Am J Trop Med Hyg. 2014 Aug;91(2):435-6.
  44. Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, Bloom BR, Modlin RL. IL-32 is a molecular marker of a host defense network in human tuberculosis. Sci Transl Med. 2014 Aug 20;6(250):250ra114.

Early Publications

  1. Bloom BR, Bennett B. Mechanism of a reaction in vitro associated with delayed‑type hypersensitivity. Science. 1966; 153:80‑2.
  2. Jacobs WR Jr., Tuckman M, Bloom BR. Introduction of foreign DNA into mycobacteria using a shuttle
  3. Stover CK, de la Cruz VF, Fuerst TR, Burlein JE, Benson LA, Bennett LT, Bansal GP, Young JF, Lee MH, Hatfull GF, Snapper SB, Barletta RG, Jacobs WR Jr., Bloom BR. New use of BCG for recombinant vaccines.  1991; 351:456-60.
  4. Flynn JL, Chan J, Triebold KJ, Dalton DK, Stewart TA, Bloom BR. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis J Exp Med. 1993; 178:2249-54.
  5. Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik S, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006; 311:1770-3.