Mass Spectometry scientist in lab
Mass Spectometry scientist in lab
Cardiovascular disease is the number one killer globally. Some of the risk factors for heart disease, such as smoking and high cholesterol, are well recognized and the focus of intensive research and policy efforts. However, new therapeutic approaches and changing life styles generate new risks, such as widespread obesity, that impact disease incidence and progression. Research on these risk factors is needed in order to generate new tools for managing heart health.

New research tools are providing a more integrated understanding of CVD risk factors. Cardiovascular diseases were traditionally studied by scientists in a range of specialized disciplines, often in different institutions: cardiologists, endocrinologists, epidemiologists, nutrition scientists, health policy scientists and advocates, as well as scientists working on fundamental aspects of metabolism or the cardiovascular system. Advances in human genetics and basic biology are building bridges between these disciplines. Combining population sciences with basic and clinical science will reveal new insights into the fundamental causes of cardiovascular disease.

The Chan school has been a research and policy leader in areas pertaining to cardiovascular disease, conducting innovative studies in nutritional epidemiology and developing ground-breaking campaigns to end smoking. The CAP-CVD center is building on this history of innovation to study the changing risk landscape of cardiovascular disease.

Our approach

CAP-CVD brings together interdisciplinary scientists from the basic biological sciences and population scientists at the Chan school. The center is organized around the following three programs:

  • Developing and supporting collaborative research projects that address the underlying causes of metabolic risk for cardiovascular disease (Click here for more)
  • Financial support of junior faculty in the Departments of Nutrition and Molecular Metabolism who are conducting groundbreaking research in metabolism and cardiovascular disease (Click here for more)
  • Developing and deploying state-of-the-art analytics to apply to population as well as basic science questions (Click here for more)

Core values of the CAP-CVD center include dedication to scientific excellence and rigor, and a commitment to open communication and rapid sharing of reagents and results generated by interdisciplinary research.


Shilpa Bhupathiraju

Assistant Professor of Nutrition

Robert V. Farese, Jr.

Professor of Molecular Metabolism
Chair, Department of Molecular Metabolism

Frank Hu

Fredrick J. Stare Professor of Nutrition and Epidemiology
Chair, Department of Nutrition

Sheng (Tony) Hui

Assistant Professor of Molecular Metabolism

Kyu Ha Lee

Assistant Professor of Integrative Genomic Epidemiology

Eric Rimm

Professor in the Departments of Epidemiology and Nutrition

Tobias Walther

Professor of Molecular Metabolism
Executive Director, Harvard Chan School Analytics Center
Director, Center on Causes and Prevention of Cardiovascular Disease
Howard Hughes Medical Institute Investigator