MOTIVATION FOR THE MetRISK CVD AWARDS
Cardiovascular disease is the number one killer on the globe. While some risks have been managed well at least in some parts of the world (e.g., smoking, high cholesterol), others remain. Moreover, changing life style has generated new risk factors, particularly linked to changing patterns of nutrition and pathologies linked to obesity. Understanding the causes of changed cardiovascular risk due to these changes in nutrition requires an interdisciplinary approach combining population and mechanistic sciences. To advance this goal, and to strengthen the interface between population and basic sciences, the Center for Causes and Prevention of Cardiovascular Disease (CAP-CVD) soliciting proposals for projects from teams including at least one member from both the Departments of Nutrition and Molecular Metabolism (MET).
Successful projects will provide faculty the opportunity to develop novel research ideas. Although not required, projects capitalizing on our significant strengths in studying population cohorts, advanced biological analytics and metabolism research are encouraged.
I. Combine public health expertise in population studies with expertise in basic biology and advanced analysis of metabolism, with potential to transform the implementation and practice of cardiovascular disease prevention and early detection.
II. Position awardees to be highly competitive for larger external collaborative grant mechanisms.
Junior Faculty Development
One of the pillars of the CAP-CVD program is to support young investigators in the field of cardiovascular research. Our goal is to provide salary and career support for one investigator per year.
2019 CAP-CVD Faculty Sheng (Tony) Hui
Tony Hui studied Physics at Hong Kong Baptist University. He then earned a PhD in Biophysics from the University of California, San Diego in 2014. After completing postdoctoral training at Princeton University, Dr. Hui joined Harvard as an assistant professor in October of 2019. The Hui lab’s overarching goal is to understand mammalian energy metabolism, which involves the constant burning of dietary carbons into CO2, in order to develop strategies for treating diseases caused by energy imbalance. Research centers on the factors that determine dietary intake and energy expenditure and how these two processes synergize to achieve energy balance in the body. The Hui lab uses tools for in vivo flux quantification of metabolic diseases like obesity and cachexia, integrating animal experiments, mass spectrometry, and quantitative modeling.
More info to come soon!