Lockdown measures and relative changes in the age-specific incidence of SARS-CoV-2 in Spain

The first months of the SARS-CoV-2 epidemic in Spain resulted in high incidence and mortality. Little is known about the epidemic dynamics in different age groups, including the relative effect of the lockdown measures introduced on March 15, and strengthened on March 30 to April 14, 2020 when only essential workers continued to work.

Reconstruction of the full transmission dynamics of COVID-19 in Wuhan

Disease modeling Infection and infection control Faculty: Xihong Lin Xihong Lin, professor of Biostatistics, and collaborators studied the transmission dynamics of the SARS-CoV-2 in Wuhan, China between January and March and found that up to 87 percent of infections in the city were undetected, potentially including asymptomatic and mildly symptomatic cases. Transmission rates during this … Continue reading “Reconstruction of the full transmission dynamics of COVID-19 in Wuhan”

Reconstruction of the full transmission dynamics of COVID-19 in Wuhan

Xihong Lin, professor of Biostatistics, and collaborators studied the transmission dynamics of the SARS-CoV-2 in Wuhan, China between January and March and found that up to 87 percent of infections in the city were undetected, potentially including asymptomatic and mildly symptomatic cases. Transmission rates during this period could have been as high as 3.54 infections per case, and were only controlled due to widespread and strict containment measures and interventions.

Measuring the resilience of nursing homes facing COVID-19

Why are nursing home populations so vulnerable, and what can be done to address these vulnerabilities for current and future COVID-19 waves? Mental and physical health Policy and protocol Infection and infection control Faculty Michael Barnett, Yonatan Grad Summary COVID-19 presents the greatest challenge in recent memory for the frailest, most vulnerable individuals in the … Continue reading “Measuring the resilience of nursing homes facing COVID-19”

U.S. County-Level Characteristics to Inform Equitable COVID-19 Response

How biological, demographic, and socioeconomic factors are likely to determine an individual’s susceptibility to COVID-19. Infection and infection control Global impact and response Faculty Caroline Buckee, Satchit Balsari Summary The spread of Coronavirus Disease 2019 (COVID-19) across the United States confirms that not all Americans are equally at risk of infection, severe disease, or mortality. … Continue reading “U.S. County-Level Characteristics to Inform Equitable COVID-19 Response”

Age as a COVID-19 Risk Factor

What role does age play in COVID-19 severity and mortality? Mental and physical health Infection and infection control Faculty Jin-Ah Park, Phyllis Kanki Summary To develop effective and safe therapeutic treatments for SARS-CoV-2 infection, understanding the pathogenesis of SARS-CoV-2 at a cellular level is urgently needed. Age is one of the key risk factors associated … Continue reading “Age as a COVID-19 Risk Factor”

Implications of the Age Profile of the Novel Coronavirus

What role do children play in the transmission of SARS-CoV-2? Mental and physical health Infection and infection control Faculty Michael Mina, William Hanage, Summary The role of children in the transmission of SARS-CoV-2 remains unclear, and existing data are yet to provide a consistent explanation for the markedly skewed age distribution of COVID-19 cases. Whereas … Continue reading “Implications of the Age Profile of the Novel Coronavirus”