The global epidemics of obesity, diabetes and associated diseases are leading causes of mortality in the 21st century. Environmental exposures, such as exposure to several chemicals released in our environments, may have a role in the complex etiology of these epidemics, in combination with excessive caloric intakes, sedentary lifestyles and genetic predisposition. The main focus of my research is the impact of environmental chemicals on maternal metabolic health, pregnancy outcomes and newborn’s growth and development through adulthood. I currently work with colleagues and collaborators on data from prospective cohorts of children and adults in the Faroe Islands, the U.S., Spain and other world regions. My studies aim to shed light on the metabolic health consequences and mechanistic pathways associated with chemicals classified as endocrine disruptors, including perfluoroalkyl substances, organochlorine pesticides, phenols, phthalates, and toxic metals.
M.D., 2007, University of Crete, Greece
M.P.H., 2010, Pompeu Fabra University & Barcelona Autonoma University, Spain
Ph.D. in Biomedicine-Environmental Health, 2014, Pompeu Fabra University, Spain
Zong G, Valvi D, Coull B, Goen T, Hu FB, Nielsen F, Grandjean P, Sun Q. Persistent organic pollutants and risk of type 2 diabetes: A prospective investigation among middle aged women in Nurses’ Health Study II. Environ Int 2018 (in press)
Montazeri P, Vrijheid M, Martinez D, Basterrechea M, Fernandez-Somoano A, Guxens M, Iñiguez C, Lertxundi A, Murcia M, Tardon A, Sunyer J, Valvi D. Maternal metabolic health parameters during pregnancy in relation to early childhood BMI trajectories. Obesity (Silver Spring) 2018;26(3):588-96.
Valvi D, Oulhote Y, Weihe P, Dalgard C, Bjerve K, Steuerwald U, Grandjean P. Gestational diabetes and offspring birth size at elevated environmental pollutant exposures. Environ Int 2017;107:205-15.
Karlsen M, Grandjean P, Weihe P, Steuerwald U, Oulhote Y, Valvi D. Early-life exposures to persistent organic pollutants in relation to overweight in preschool children. Reprod Toxicol 2017; 68: 145-153.
Matilla-Santander N, Valvi D, Lopez-Espinosa MJ, Manzano-Salgado CB, Ballester F, Ibarluzea J, Santa-Marina L, Schettgen T, Guxens M, Sunyer J, Vrijheid M. Exposure to perfluoroalkyl substances and metabolic outcomes in pregnant women: Evidence from the Spanish INMA birth cohorts. Environ Health Perspect 2017;125(11):117004.
Valvi D, Casas M, Romaguera D, Monfort N, Ventura R, Martinez D, Sunyer J, Vrijheid M. Prenatal phthalate exposure and childhood growth and blood pressure: Evidence from the Spanish INMA-Sabadell Birth Cohort Study. Environ Health Pespect 2015; 123(10):1022-9.
NCD Risk Factor Collaboration (NCD-Risc). Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet 2017;290(10113):2627-2642.