Georgios Pyrgiotakis

Visiting Scientist

Department of Environmental Health

Peer Reviewed Journal Articles (citations: 1516, h-index 14, Source: Google Scholar)

  1. Pyrgiotakis G.; Vedantam P.; Cirenza C.; McDevitt J.; Eleftheriadou M.; Leonard S.; Demokritou P.; Optimization of an antimicrobial platform for food applications with the Engineered Water Nanostructures (EWNS) – Accepted Scientific Reports
  2. DeLoid, G.M.; Cohen, J.; Pyrgiotakis, G.; Pirela, S.; Pal, A.; Liu J.; Srebric, J.; Demokritou, P. Advanced computational modeling for in vitro nanomaterial dosimetry – Particle and Fibre Toxicology, 2015, 12 (32), 10.1186/s12989-015-0109-1
  3. Pyrgiotakis, G.; Vasanthakumar, A.; Gao, Y.; Eleftheriadou, M.; Toledo, E; DeAraujo, A.; McDevitt, J.; Han, T.W.; Mainelis, G.; Mitchell, R.; Demokritou, P. Inactivation of foodborne microorganisms on stainless steel surfaces and tomatoes using Engineered Water Nanostructures (EWNS), 2014, Environmental Science and Technology, 2015, 49 (6), pp 3737–3745,
  4. Molina, R. M.; Konduru, N. V.; Jimenez, R. J., Pyrgiotakis, G; Demokritou, P.; Wohlleben, W.;  Brain, J.D.; Bioavailability, distribution and clearance of tracheally instilled, gavaged or injected cerium dioxide nanoparticles and ionic cerium, Environmental Science: Nano, 2014, 1, DOI: 10.1039/C4EN00034J
  5. Okello, V.A.; Gass, S.; Pyrgiotakis, G.; Dub, N.; Lake, A.; Kariuki, V.; Sotiriou, G. A.; Addolorato, J; Demokritou P., Sadik, O.A.; Capture, isolation and electrochemical detection of industrially-relevant engineered aerosol nanoparticles using poly (amic) acid, phase-inverted, nano-membranes, Journal of Hazardous Materials, 2014, DOI: 10.1016/j.jhazmat.2014.06.081
  6. Pyrgiotakis, G.; Blattmann, C.; Demokritou, P.; Real-time Nanoparticle-Cell interactions in physiological media by Atomic Force Microscopy. ACS Sustainable Engineering & Chemistry. 2014, 10.1021/sc500152g
  7. Pirela, S.; Pyrgiotakis, G.; Dhimiter, B.; Treye, T.; Castranova, V.; Demokritou, P. Development and Characterization of an Exposure Platform Suitable for Physico-Chemical, Morphological and Toxicological Characterization of Printer Emitted Particles (PEPs). Inhalation Toxicology, 2014, 26(7), 400-408
  8. Pyrgiotakis, G.; McDevitt J. Gao Y.; Branco A; Eleftheriadou M; Lemos B.; Nardell E.; Demokritou P. Mycobacteria inactivation using Engineered Water Nanostructures (EWNS). Nanomedicine -NBM, 2014, doi:10.1016/j.nano.2014.02.016
  9. Watson, C.; Ge, J.; Cohen, J.; Pyrgiotakis, G.; Engelward, B. P.; Demokritou, P. A High Throughput Screening Platform for Engineered Nanoparticle Mediated Genotoxicity Using CometChip Technology. ACS Nano 2014, 8 (3), 2118–2133
  10. DeLoid, G.; Cohen, J. M.; Darrah, T.; Pyrgiotakis, G.; Wohlleben, W.; Demokritou, P. Nanomaterial Effective Density for In Vitro Dosimetry by Volumetric Centrifugation., Nature Communications, 2014, 5:3514, doi:10.1038/ncomms4514
  11. Sotiriou, G. A.; Watson, C.; Murdaugh, K. M.; Darrah, T. H.; Pyrgiotakis, G.; Elder, A.; Brain, J. D.; Demokritou, P.; Engineering Safer-by-Design, Transparent, Silica-coated ZnO Nanorods with Reduced DNA Damage Potential. Environmental Science: Nano, 2014, 1, 144-153
  12. Pyrgiotakis, G.; McDevitt, J.; Bordini, A.; Diaz, E.; Molina, R.; Watson C.; Lenard S.; Fix N.; Mizuyama Y.; Brain J.; Demokritou P. A Nanotechnology-based Method for Airborne Bacterial Inactivation using Engineered Water Nanodroplets. RSC Environmental Science: Nano, 2014, 1, 15-29
  13. Pyrgiotakis, G.; Blattmann, C.O.; Pratsinis, S.E.; Demokritou, P. Nanoparticle-nanoparticle interactions in biological media by Atomic Force Microscopy, Langmuir 2013, 29, 11385-11395
  14. Demokritou, P.; Gass, S.; Pyrgiotakis, G.; Cohen, J. M.; Goldsmith, W.; McKinney, W.; Frazer, D.; Ma, J.; Schwegler-Berry, D.; Brain, J.; et al. An in Vivo and in Vitro Toxicological Characterisation of Realistic Nanoscale CeO2 Inhalation Exposures. Nanotoxicology 2013, 7, 1338-1350.
  15. S. Gass, J. M. Cohen, G. Pyrgiotakis, G. A. Sotiriou, S. E. Pratsinis and P. Demokritou. “Safer Formulation Concept for Flame-Generated Engineered Nanomaterials”. ACS Sustainable Chemistry & Engineering 2013, 1, 843-857.
  16. Pyrgiotakis, G.; McDevitt, J.; Yamauchi, T.; Demokritou, P. A Novel Method for Bacteria Inactivation Using Engineered Water Nanostructures. J. Nanopart. Res. 2012, 1-14.
  17. Cohen, J.; DeLoid, G.; Pyrgiotakis, G.; Demokritou, P. Interactions of Engineered Nanomaterials in Physiological Media and Implications for in Vitro dosimetry. Nanotoxicology 2012, 7, 417–431.
  18. Guarracino, M. R.; Xanthopoulos, P.; Pyrgiotakis, G.; Tomaino, V.; Moudgil, B. M.; Pardalos, P. M. Classification of Cancer Cell Death with Spectral Dimensionality Reduction and Generalized Eigenvalues. Artif. Intell. Med., 2011, 53, 119–125
  19. Pyrgiotakis, G.; Kundakcioglu, O. E.; Pardalos, P. M.; Moudgil, B. M. Raman Spectroscopy and Support Vector Machines for Quick Toxicological Evaluation of Titania Nanoparticles. J Raman Spectroscopy,  2011, 42, 1222–1231.
  20. Karaka, F.; Pyrgiotakis, G.; Çelik, M.; Moudgil, B. M. Na-Bentonite and MgO Mixture as a Thickening Agent for Water-Based Paints. KONA Powder and Particle Journal 2011, 29, 96–106.
  21. Fenn, M. B.; Xanthopoulos, P.; Pyrgiotakis, G.; Grobmyer, S. R.; Pardalos, P. M.; Hench, L. L. Raman Spectroscopy for Clinical Oncology. Adv. Opt. Tech. 2011, 2011, 1–20.
  22. Sharma, P.; Brown, S. C.; Singh, A.; Iwakuma, N.; Pyrgiotakis, G.; Krishna, V. B.; Knapik, J. A.; Barr, K.; Moudgil, B. M.; Grobmyer, S. R. Near-Infrared Absorbing and Luminescent Gold Speckled Silica Nanoparticles for Photothermal Therapy. J. Mater. Chem. 2010, 20, 5182–5185.
  23. Pyrgiotakis, G.; Sigmund, W. M. X-Ray Photoelectron Spectroscopy of Anatase-TiO2 Coated Carbon Nanotubes. Solid State Phenomena, 2010, 162, 163–177.
  24. Pyrgiotakis, G.; Kundakcioglu, O. E.; Finton, K.; Pardalos, P. M.; Powers, K.; Moudgil, B. M. Cell Death Discrimination with Raman Spectroscopy and Support Vector Machines. Ann. Biomed. Eng. 2009, 37, 1464– 1473.
  25. Woan, K.; Pyrgiotakis, G.; Sigmund, W. M. Photocatalytic Carbon-Nanotube-TiO2 Composites. Adv. Mater. 2009, 21, 2233–2239.
  26. Bhowmick, T. K.; Pyrgiotakis, G.; Finton, K.; Suresh, A. K.; Kane, S. G.; Moudgil, B. M.; Bellare, J. R. A Study of the Effect of JB Particles on Saccharomyces Cerevisiae(Yeast) Cells by Raman Spectroscopy. J Raman Spectrosc., 2008, 39, 1859–1868.
  27. Pyrgiotakis, G.; Bhowmick, T. K.; Finton, K.; Suresh, A. K.; Kane, S. G.; Bellare, J. R.; Moudgil, B. M. Cell (A549)-Particle (Jasada Bhasma) Interactions Using Raman Spectroscopy. Biopolymers 2008, 89, 555–564.
  28. Pyrgiotakis G.; Sigmund, W.; Carbon Nanotubes as Photocatalytic Carriers, Ceramic Transactions, 2007, 198, 205-210.
  29. Sigmund, W. M.; Yuh, J.; Park, H.; Maneeratana, V.; Pyrgiotakis, G.; Daga, A.; Taylor, J.; Nino, J. Processing and Structure Relationships in Electrospinning of Ceramic Fiber Systems. J. Am. Chem. Soc. 2006, 89, 395– 407.
  30. Kim, B.; Pyrgiotakis, G.; Sauers, J.; Sigmund, W. The Effect of Monolayers’ Alkyl Chain Length on Atomic Force Microscopy Anodization Lithography. Colloid Surface A 2005, 253, 23–26.
  31. Lee, S.; Pyrgiotakis, G.; Sigmund, W. M. TiO2-Carbon Nanotube Nanocomposite Particles. Journal of the European Academy of Sciences 2004, 1.
  32. Manjooran, N.; Lee, S.; Pyrgiotakis, G.; Sigmund, W. Ceramic Slurries for Electrodeposition in Rapid- Prototyping Applications. Am. Ceram. Soc. Bull. 2004, 83, 9301–9303.
  33. Kim, B.; Pyrgiotakis, G.; Sigmund, W. Dip-Pen Nanolithography with Poly(Diallyl Dimethyl Ammonium) Chloride. J. Nanosci. Nanotechn. 2004, 4, 221–225.


  1. DeLoid G.M.; Casella B; Pirela S.; Filoramo R.; Pyrgiotakis G.; Demokritou P.l Kobzik L. Effects of engineered nanomaterial exposure on macrophage innate immune function – ACS Nano, Under Review

In preparation

  1. Vedantam P.; Eleftheriadou M.; Pyrgiotakis G.; Cirenza C.; McDevitt J.; Demokritou P.; Inactivation of Natural Flora on Cherry tomatoes using the Engineered Water Nanostructures (EWNS)

Book Chapters

  1. Pyrgiotakis, G. Carbon Nanostructures for Enhanced Photocatalysis for biocidal applications, Handbook of Nanomaterials Properties Editors: W. Sigmund, M. Shanmugam and V. Zinyuk Spinger, Springer, 2014, ISBN 978-3-642-31107-9
  2. Pyrgiotakis, G.; Sigmund, W. Photocatalytic Particles for Biocidal Applications, Particulate Systems in nano- and bio- technologies. Editors: W. Sigmund, H. El-Shall, D.O. Shah and B. Moudgil. RCR Press, 2008, ISBN: 9780849374364
  3. Sigmund, W.; Pyrgiotakis, G.; Daga, A. Theory and Applications of Colloidal Processing, Chemical Processing of Ceramics, 2nd Edition, Editors: Burtrand I. Lee and Sridhar Komarneni, CRC Press, 2005, ISBN 1574446487
  1. Christian Bohling, Cho, J.; Pyrgiotakis, G.; Sigmund, W. Surface Forces on Nanoparticles Determined by Direct Measurement, Dekker Encyclopedias of Nanoscience and Nanotechnology – Third Edition, Editor H. Nalwa, Marcel Dekker Inc., 2014, ISBN 9781439891346 – Revised
  2. Cho, J.; Pyrgiotakis, G.; Sigmund, W. Surface Forces on Nanoparticles Determined by Direct Measurement, Dekker Encyclopedias of Nanoscience and Nanotechnology First Edition, Editor H. Nalwa, Marcel Dekker Inc., 2004, ISBN 1849735956


  1. Demokritou, P.; Pyrgiotakis, G.; Brain J.; “Engineered Water Nanostructures (EWNS) and uses thereof”, 2015, 62/050,996
  2. Sigmund, W.; Daga, A.; Yuh J.; Pyrgiotakis, G.; Taylor, J.; Park, H.; “Ceramic nanoparticles and methods for forming ceramic nanoparticles from electrospun nanofibers”, 2006, Patent Number WO2007109304 A2
  3. Sigmund, W.; Lee, S.-H.; Koopman, B.; Moudgil, B. M.; Pyrgiotakis, G.; Krishna, V. B. “Photocatalytic Nanocomposites and Applications Thereof”, 2005, Patent Number US20080045770 A1

Peered Reviewed Proceedings

  1. Gass, S.; Pyrgiotakis, G.; Cohen, J.M.; Sotiriou, G.A.; Pratsinis, S.E.; Demokritou, P. A safer formulation concept for flame-generated engineered nanomaterials, Nanotech 2012 Conference Proceedings Vol. 3, ISBN: 978-1-4665-6274-5, 2012, p. 323 – 326
  2. Pyrgiotakis, G.; McDevitt, J.; Yamauchi, T.; Demokritou, P. A novel method for bacteria inactivation using Engineered Water Nanostructures. Nanotech 2012 Conference Proceedings Vol. 1, ISBN: 978-1-4665-6276-9, 2012, p. 421 – 424,
  3. Pyrgiotakis, G.; Sigmund, W.; Titania-Carbon Nanotube Composite for Enhanced Photocatalysts, 2nd International Conference & Exposition on Advanced Ceramics & Composites, Daytona Beach, 2008
  4. Sigmund, W.; Pyrgiotakis, G.; Krishna, V.; Lee, S.-H.; Pumprueg, S.; Koopman, B.; Moudgil, B. Photocatalytic Destruction of Bioparticles, IEEE International Conference, Proceedings TEHOSS 2005, Ed. A. Stepnowski, Co-Eds. A Rucinski, K. Kosmowski, ISBN 83-917681-9-8, 2005, p. 479-486
  5. Pyrgiotakis, G.; Sigmund, W.; Advanced Photocatalysis with Anatase Nanocoated Multi-walled Carbon Nanotubes. Proceedings of MRS Spring Meeting 2005: Symposium R Nanoporous and Nanostructured Materials for Catalysis, Sensor, and Gas Separation Applications, Editors: S.W. Lu, H. Hahn, J. Weissmuller, J.L. Gole, San Francisco, 2005, p. R5.7
  6. Manjooran, N.J.; Lee, S.-W.; Pyrgiotakis, G.; Sigmund, W.; Rheology of Ceramic Slurries for Electro-Deposition in Rapid Prototyping Applications. Proceedings of ACerS Meeting 2004: Colloidal Ceramic Processing of Nano-, Micro-, and Macro-Particulate Systems, Editors: W.-H. Shih, Y. Hirata, W. Carty, 2004 , p. 75-81