Georgios Sotiriou

Research Fellow

Department of Environmental Health

Center for Nanotechnology & Nanotoxicology

email: sotiriou@hsph.harvard.edu

Currently an Assistant Professor at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet, Stockholm, Sweden.

More info: http://ki.se/en/people/geosot

Lab website: https://sotirioulab.net 

Research interests

Nanoscale functional materials and devices for biomedical applications

Nanostructured materials show great potential in the biomedical field as they can serve as superior bioimaging contrast agents, diagnostic and therapeutic tools. Antibacterial nanosilver, plasmonic nanosized noble metals, quantum dots, nanophosphors and superparamagnetic nanoparticles constitute some of such functional materials. For example, nanoparticles that emit light light upon excitation (e.g. nanophosphors, quantum dots), superparamagnetic (e.g. Fe2O3) and plasmonic nanoparticles (e.g. Au, Ag) can be used as “nanotools” in bio-applications. Here, we synthesize such nanoparticles and investigate the parameters that influence their properties, targeting superior performance in diagnostics and therapeutic applications. Novel nanoscale systems and devices will be fabricated using such functional materials aiming to tackle specific medical and pharmaceutical problems.

ACS Nano vol. 6, pp. 3888-3897 (2012).
ACS Nano vol. 6, pp. 3888-3897 (2012).

Links

Selected Publications

Statistics

  • Total number of publications: 39 (37 original research articles, 2 reviews)
  • First author: 19
  • Corresponding author: 5
  • Without PhD supervisor: 17
  • Total citations: 982 (ISI Web of Science), 1145 (Scopus), 1476 (Google Scholar)
  • h-index: 18 (ISI Web of Science), 19 (Scopus), 19 (Google Scholar)
  • Total IF: 268.6

For full list please click the Publications link

A. Spyrogianni, I. K. Herrmann, M. S. Lucas, J-C. Leroux & G. A. Sotiriou. “Quantitative analysis of the deposited nanoparticle dose on cell cultures by optical absorption spectroscopy” Nanomedicine 11, 2483-2496 (2016)link

-Corresponding author

A. Teleki, F. L. Haufe, A. M. Hirt, S. E. Pratsinis & G. A. Sotiriou. “Highly scalable production of uniformly-coated superparamagnetic nanoparticles for triggered drug release from alginate hydrogels” RSC Adv6, 21503-21510 (2016). link

-Corresponding author

G.A. Sotiriou, G.D. Etterlin, A. Spyrogianni, F. Krumeich, J-C. Leroux & S.E. Pratsinis. “Plasmonic biocompatible silver-gold alloyed nanoparticles”, Chem. Comm. 50, 13559-13562 (2014). link

G.A. Sotiriou, F. Starsich, A. Dasargyri, M.C. Wurnig, F. Krumeich, A. Boss, J-C. Leroux, S.E. Pratsinis. “Photothermal Killing of Cancer Cells by the Controlled Plasmonic Coupling of Silica-coated Au/Fe2O3 Nanoaggregates”, Adv. Funct. Mater. 24, 2818-2827 (2014). link

Sotiriou_AdvFunctMater_2014_frontispiece small

  • Frontispiece of issue published on 21 May 2014: link
  • Featured in ETH Newslink
  • Featured in IEEE Spectrum: link
  • Featured in InterPharma.ch (in German): link
  • Featured in MedGadget: link
  • Featured in NANOTECH ETC: link
  • Featured in inPharma-Technologist: link
  • Featured in Medizin & Technik (in German): link

G.A. Sotiriou, C. Watson, K.M. Murdaugh, T.H. Darrah, G. Pyrgiotakis, A. Elder, J.D. Brain, P. Demokritou. “Engineering Safer-by-Design, Transparent, Silica-coated ZnO Nanorods with Reduced DNA Damage Potential”, Environ. Sci.: Nano 1, 144-153 (2014). link

Safer ZnO

  • Featured in RSC Chemistry Worldlink
  • Featured in Harvard Gazettelink
  • Featured in HSPH News: link
  • Featured in ASPPH Friday Letters: link
  • Featured in Süddeutsche.de (in German): link

A. Pratsinis, P. Hervella, J-C. Leroux, S.E. Pratsinis, G.A. Sotiriou, “Toxicity of Silver Nanoparticles in Macrophages”, Small 9, 2576-2584 (2013). link

G.A. Sotiriou, C.O. Blattmann, S.E. Pratsinis, “Flexible, Multifunctional, Magnetically Actuated Nanocomposite Films”, Adv. Funct. Mater. 23, 34-41 (2013). link

G.A. Sotiriou, E. Diaz, M. S. Long, J. Godleski, J. Brain, S.E. Pratsinis, P. Demokritou, “A Novel Platform for Pulmonary and Cardiovascular Toxicological Characterization of Inhaled Engineered Nanomaterials”, Nanotoxicology 6, 680-690 (2012). link

G.A. Sotiriou, D. Franco, D. Poulikakos, A. Ferrari, “Optically Stable Biocompatible Flame-Made SiO2-Coated Y2O3:Tb3+ Nanophosphors for Cell Imaging”, ACS Nano 6, 3888–3897 (2012). link

G.A. Sotiriou, A. Hirt, P.-Y. Lozach, A. Teleki, F. Krumeich, S.E. Pratsinis, “Hybrid Silica-coated, Janus-like Plasmonic-Magnetic Nanoparticles”, Chem. Mater. 23, 1985-1992 (2011). link

Chem. Mater. vol. 23, pp. 1985-1992 (2011).

 

Featured in ETH lifelink

 

G.A. Sotiriou, T. Sannomiya, A. Teleki, F. Krumeich, J. Vörös, S.E. Pratsinis, “Non-toxic, Dry-coated Nanosilver for Plasmonic Biosensors”, Adv. Funct. Mater. 20, 4250-4257 (2010). link

Adv. Funct. Mater. vol. 20, pp. 4250-4257 (2010).

 

Frontispiece of issue published on 21 Dec 2010link

 

 

G.A. Sotiriou, S.E. Pratsinis, “Antibacterial Activity of Nanosilver Ions and Particles”, Environ. Sci. Technol. 44, 5649-5654 (2010). link

-Highly cited paper (Web of Science): Top 1% of its academic field based on a highly cited threshold for the field and publication year.