Skin colonization with methicillin resistant S. aureus (MRSA) is a major risk factor for invasive MRSA infections.While decolonization protocols reduce rates of carriage, they are not always successful. To investigate the factors that contribute to persistent colonization and response to the decolonization procedure, we are collaborating with Susan Huang and colleagues to analyze MRSA data from the clinical trial Project CLEAR. As part of this effort, we are testing a microfluidics device developed in Paul Blainey’s lab for inexpensive, high throughput pathogen DNA isolation and library construction for genome sequencing.
