Jaime Hart

Assistant Professor in the Department of Environmental Health

Department of Environmental Health

Research

Broadly my research focuses on environmental and occupational risk factors of chronic diseases, including cardiovascular disease, cancer, COPD, rheumatoid arthritis, and reproductive systems. I have mainly focused my research on the effects of air pollution and traffic exposure in the general population and in workers from the railroad and trucking industries. I am particularly interested in incorporating geographic information system (GIS) technologies and spatial statistics into these fields to improve exposure assessment, control for area level confounding by factors such as socioeconomic status (SES), and to explore the geographic distributions of disease. I have primarily worked with data from large cohort studies based at Brigham and Women’s Hospital and the Harvard School of Public Health, such as the Nurses’ Health Studies (NHS, NHSII, and NHS3), the Health Professionals’ Follow-up Study, the US Railroad Workers Study, and the Trucking Industry Particle Study.

Teaching

I currently co-teach two of the core courses in the EER Program’s MS curriculum, EH508 (the Environmental Exposure, Epidemiology and Risk Thesis Course) and EH263 (Analytical Methods and Exposure Assessment). Starting in the summer of 2016, I will be teaching ID215 (Environmental and Occupational Epidemiology).

Recent Publications (~2013 onwards)

My full list of publications can be viewed here

Zhang Z, Laden F, Forman JP, Hart JE. Long-term exposure to particulate matter and self-reported hypertension, a prospective analysis in the Nurses’ Health Study.  Environmental Health Perspectives.  2016; 124(9): 1414-20. PubMed PMID: 27177127.  PubMed Central PMCID: PMC5010392.

Fisher JA, Puett RC, Hart JE, Camargo Jr CA, Varraso R, Yanosky JD, Laden F.  Particulate matter exposures and adult-onset asthma and COPD in the Nurses’ Health Study.  European Respiratory Journal.  2016; 48(3): 921-4. PubMed PMID: 27288040.

James P*, Jankowska M*, Marx C, Hart JE, Berrigan D, Kerr J, Hurvitz PM, Hipp JA, Laden F. “Spatial Energetics”: Integrating data from GPS, accelerometry, and GIS to address obesity and inactivity. American Journal of Preventive Medicine. 2016; S0749-3797(16):30227-6. PubMed PMID: 27528538. PubMed Central PMCID: PMC5067207 (*co-first authors).

Hart JE, Bertrand KA, DuPre N, James P, Vieira VM, Tamimi RM, Laden F.  Long-term particulate matter exposures during adulthood and risk of breast cancer incidence in the Nurses’ Health Study II prospective cohort.  Cancer, Epidemiology, Biomarkers, and Prevention. 2016; 25(8): 1274-1276. PubMed PMID: 27257091. PMCID PMC4970922.

Chiu YM, Garshick E, Hart JE, Spiegelman D, Dockery DW, Smith TJ, Laden F. Occupational vehicle-related particulate matter exposure and inflammatory markers in trucking industry workers. Environ Res. 2016; 148:310-317. PubMed PMID: 27104805.  PubMed Central PMCID: PMC4874883.

James P. Hart JE, Banay RF, Laden F.  Exposure to greenness and mortality in a nationwide prospective cohort study of women. Environmental Health Perspectives. 2016.  in press.  PubMed PMID: 27074702.  PubMed Central PMCID: PMC5010419.

Mahalingaiah S*, Hart JE*, Laden F, Farland LV, Hewlett MM, Chavarro J, Aschengrau A, Missmer SA. Adult air pollution exposures and risk of infertility in the Nurses’ Health Study II. Human Reproduction. 2016;31(3):638-47. PubMed PMID:26724803. PubMed Central PMCID: PMC4755443. (*co-first authors).

Hart JE, Morse L, Tun CG, Brown R, Garshick E. Cross-sectional associations of pulmonary function with systemic inflammation and oxidative stress in individuals with chronic spinal cord injury. The Journal of Spinal Cord Medicine. in press. PubMed PMID: 26180939. PubMed Central PMCID in progress.

Pun VC, Hart JE, Kabrhel C, Camargo CA Jr, Baccarelli AA, Laden F. Prospective study of ambient particulate matter exposures and risk of pulmonary embolism in the Nurses’ Health Study cohort. Environmental Health Perspectives. 2015; 123(12): 1265-70. PubMed PMID: 25956005. PubMed Central PMCID: PMC4671228.

Hart JE, Puett RC, Rexrode KM, Albert CM, Laden F. Effect modification of long-term air pollution exposures and the risk of incident cardiovascular disease in US women. Journal of the American Heart Association. 2015; 4(12): pii: e002301. PubMed PMID: 26607712. PubMed Central PMCID:PMC4845261.

VoPham T, Brooks MM, Yuan J-M, Talbott EO, Ruddell D., Hart JE, Chang C-CH, Weissfeld JL. Pesticide exposure and hepatocellular carcinoma risk: a case-control study using a geographic information system (GIS) to link SEER-Medicare and California pesticide data. Environmental Research. 2015; 143:68-82. PubMed PMID: 26451881. PubMed Central PMCID: PMC4641787.

James P, Hart JE, Arcaya MC, Feskanich D, Laden F. Subramanian SV. Neighborhood self-selection: The role of pre-move health factors on the built and socioeconomic environment. International Journal of Environmental Research and Public Health. 2015; 12:12489-504. PubMed PMID: 26457712. PubMed Central PMCID: PMC4626981.

James P, Hart JE, Laden F. Neighborhood walkability and particulate air pollution in a nationwide cohort of women. Environmental Research. 2015: 142:703-711. PubMed PMID: 26397775. PubMed Central PMCID: PMC4627661.

James P, Banay RF, Hart JE, Laden F. A review of the health benefits of greenness. Current Epidemiology Reports. 2015: 2(2):131-142. PubMed PMID: 26185745. PubMed Central PMCID:PMC4500194.

Hart JE, Spiegelman D, Beelen R, Hoek G, Brunekreef B, Schouten LJ, van den Brand P. Long-term ambient residential traffic-related exposures and measurement error–adjusted risk of incident lung cancer in the Netherlands Cohort Study on Diet and Cancer. Environmental Health Perspectives. 2015:123(9):860-866. PubMed PMID: 25816363. PubMed Central PMCID: PMC4559954.

Verner M-A, Hart JE, Sagiv SK, Bellinger DC, Altshul LM, Korrick SA. Measured prenatal and estimated postnatal levels of Polychlorinated Biphenyls (PCBs) and ADHD-related behaviors in 8-year-old children. Environmental Health Perspectives. 2015:123(9):888-894. PubMed PMID: 25769180. PubMed Central PMCID: PMC4559949.

Hart JE, Liao X, Hong B, Puett RC, Yanosky JD, Suh H, Kioumourtzoglou M-A, Spiegelman D, Laden F. The association of long-term exposure to PM2.5 on all-cause mortality in the Nurses’ Health Study and the impact of measurement-error correction. Environmental Health. 2015:14:38. PubMed PMID: 25926123. PubMed Central PMCID: PMC4427963.

Power MC, Kioumourtzoglou M, Hart JE, Okereke OI, Laden F, Weisskopf M. The relation between past exposure to fine particulate air pollution and prevalent anxiety: an observational cohort study. BMJ. 2015 Mar 24;350:h1111. PubMed PMID: 25810495. PubMed Central PMCID: PMC4373600.

Raz R, Roberts AL, Lyall K, Hart JE, Just AC, Laden F, Weisskopf MG. Autism spectrum disorder and particulate matter before, during, and after pregnancy: A nested case-control analysis within the Nurses’ Health Study II. Environmental Health Perspectives. 2015:123(3):264-270. PubMed PMID: 25522338. PubMed Central PMCID: PMC4348742.

Tamura K, Puett RC, Hart JE, Starnes HA, Laden F, Troped TJ. Spatial clustering of physical activity and obesity in relation to built environment factors among older women in three U.S. states. BMC Public Health. 2014:14(1): 1322. PubMed PMID: 25539978. PubMed Central PMCID: PMC4364109.

Hart JE, Chiuve SE, Laden F, Albert CM. Roadway proximity and risk of sudden cardiac death in women. Circulation. 2014:130(17):1474-1482. PubMed PMID: 25332277. PubMed Central PMCID: PMC4382912.

Palacios N, Fitzgerald K, Hart JE, Weisskopf M, Schwarzschild MA, Ascherio A, Laden F. Particulate matter and risk of Parkinson disease in a large prospective study of women. Environmental Health. 2014:13(1):80. PubMed PMID: 25294559. PubMed Central PMCID: PMC4201741.

Palacios N, Fitzgerald K, Roberts AL, Hart JE, Weisskppf MG, Schwarzschild MA, Ascherio A, Laden F. A prospective analysis of airborne metal exposures and risk of Parkinson disease in the Nurses Health Study Cohort. Environmental Health Perspectives. 2014;122(9):933-938. PubMed PMID: 24905870. PubMed Central PMCID: PMC4154211.

Puett RC*, Hart JE*, Yanosky JD, Spiegelman D, Wang M, Fisher J, Hong B, Laden F. Particulate matter air pollution exposure, distance to road, and incident lung cancer in the Nurses’ Health Study cohort. Environmental Health Perspectives. 2014;122(9):929-932. PubMed PMID: 24911062. PubMed Central PMCID: PMC4154215. (*co-first authors).

Mahalingaiah S*, Hart JE*, Laden F, Terry KL, Boynton-Jarrett R, Aschengrau A, Missmer SA. Air pollution and risk of uterine leiomyoma. Epidemiology. 2014:25(5):682-688. PubMed PMID:24815304. PubMed Central PMCID: PMC4209294. (*co-first authors).

Yanosky JD, Paciorek CJ, Laden F, Hart JE, Puett RC, Liao D, Suh HH. Spatio-temporal modeling of particulate air pollution in the conterminous United States using geographic and meteorological predictors. Environmental Health. 2014:13(1):63. Pubmed PMID:   25097007. PubMed Central PMCID: PMC4137272.

Neophytou AM, Hart JE, Chang Y, Zhang J, Smith TJ, Garshick E, Laden F. Short-term traffic-related exposures and biomarkers of nitro-PAH exposure and oxidative DNA damage. Toxics. 2014:2(3):377-390. Pubmed PMID: 25254201. PubMed Central PMCID: PMC4169896.

Neophytou AM, Picciotto S, Hart JE, Garshick E, Eisen EA, Laden F. A structural approach to address the healthy-worker survivor effect in occupational cohorts: an application in the trucking industry cohort. Occupational and Environmental Medicine. 2014:71(6):442-447. Pubmed PMID: 24727736. PubMed Central PMCID: PMC4051133.

James P, Berrigan D, Hart JE, Hipp JA, Hoehner CM, Kerr J, Major JM, Oka M, Laden F. Effects of buffer size and shape on associations between the built environment and energy balance. Health & Place. 2014:27:162-170. PubMed PMID: 24607875. PubMed Central PMCID: PMC4028172.

Neophytou AM, Hart JE, Cavallari J, Smith TJ, Dockery DW, Coull BA, Garshick E, Laden F. Traffic-related exposures and biomarkers of systemic inflammation, endothelial activation, and oxidative stress: a panel study in the US trucking industry. Environmental Health. 2013;12:105. PubMed PMID: 24314116. PubMed Central PMCID: PMC3882104.

Mahalingaiah S, Hart JE, Laden F, Aschengrau A, Missmer SA. Association of air pollution exposures and risk of endometriosis in the Nurses’ Health Study II. Environmental Health Perspectives. 2014;122(1):58-64. PubMed PMID: 24225723. PubMed Central PMCID: PMC3888567.

Mahalingaiah S, Hart JE, Wise LA, Terry K, Boynton-Jarrett R, Missmer SA. Prenatal Exposure to diethylstilbestrol and risk of uterine leiomyomata in the Nurses’ Health Study II: A prospective study. American Journal of Epidemiology. 2014:179(2): 186-191. PubMed PMID: 24142917. PubMed Central PMCID: PMC3873111.

Hart JE, Rimm EB, Rexrode KM, Laden F. Changes in traffic exposure and the risk of incident myocardial infarction and all-cause mortality. Epidemiology. 2013;24(5):734-742. PubMed PMID: 23877047. PubMed Central PMCID: PMC3988279.

Roberts A, Lyall K, Hart JE, Laden F, Just A, Bobb J, Koenen K, Ascherio A, Weisskopf M. Perinatal air pollutant exposures and autism spectrum disorder in the children of Nurses’ Health Study II participants. Environmental Health Perspectives. 2013;121(8):978-84. PubMed PMID: 23816781. PubMed Central PMCID: PMC3734496.

Källberg H, Vieira V, Holmqvist M, Hart JE, Costenbader KH, Bengtsson C, Klareskog L, Karlson EW, Alfredsson L. Regional differences regarding risk of developing rheumatoid arthritis in Stockholm County, Sweden: Results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study. Scandinavian Journal of Rheumatology. 2013; 42(5):337-43. PubMed PMID: 23611369. PubMed Central PMCID: PMC3815679.

Laden F, Chiu Y-H, Garshick E, Hammond SK, Hart JE. A cross-sectional study of secondhand smoke exposure and respiratory symptoms in non-current smokers in the U.S. trucking industry: SHS exposure and respiratory symptoms. BMC Public Health. 2013;13(1):93-8. PubMed PMID: 23368999. PubMed Central PMCID: PMC3655928.

Hart JE, Källberg H, Laden F, Costenbader KH, Yanosky JD, Klareskog L, Alfredsson L, Karlson EW. Ambient air pollution exposures and risk of rheumatoid arthritis. Arthritis Care & Research. 2013;65(7):1190-6. PubMed PMID: 23401426. PubMed Central PMCID: PMC3659202.

Arkema EV, Hart JE, Bertrand KA, Laden F, Grodstein F, Rosner B, Karlson EW, Costenbader KH. Exposure to Ultraviolet-B and risk of developing rheumatoid arthritis among women in the Nurses’ Health Study: A prospective cohort study. Annals of the Rheumatic Diseases. 2013;72(4):506-11. PubMed PMID: 23380431. PubMed Central PMCID: PMC3678095.

Hart JE, Garshick E, Smith TJ, Davis ME Laden F. Ischaemic heart disease mortality and years of work in trucking industry workers. Occupational and Environmental Medicine. 2013;70(8):523-8. PubMed PMID: 22992341. PubMed Central PMCID: PMC3710312.

Hart JE, Källberg H, Laden F, Bellander T, Costenbader KH, Holmqvist M, Klareskog L, Alfredsson L, Karlson EW. Ambient air pollution exposures and risk of rheumatoid arthritis: Results from the Swedish EIRA case-control study. Annals of the Rheumatic Diseases. 2013;72(6):888-94. PubMed PMID: 22833374. PubMed Central PMCID: PMC3654032.

James P, Troped PJ, Hart JE, Joshu CE, Brownson RC, Ewing R, Laden F. Urban sprawl, physical activity, and body mass index: Nurses’ Health Study and Nurses’ Health Study II. American Journal of Public Health. 2013;103(2):369-75. PubMed PMID: 22698015. PubMed Central PMCID: PMC3558772.

Press Releases and Featured News Stories

3/9/2013: Exposure to traffic pollution linked to increased risk of rheumatoid arthritis

6/18/2013: Prenatal hazardous air pollution exposure and autism risk

10/13/20134: Living near major roads may increase the risk of sudden cardiac death in women

12/18/2014: Fine particulate air pollution linked with increased autism risk

11/25/2015: Air pollution and cardiovascular disease: increased risk for women with diabetes

4/14/2016: More exposure to vegetation linked with lower mortality rates in women

4/15/2016: Mapping Boston’s soundscape

10/23/2016: Noise report cards for Boston neighborhoods

Other Affiliations

Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School

Harvard NIEHS Center for Environmental Health

Center for Research on Environmental and Social Stressors in Housing Across the Life Course (CRESSH), Project 1

Education

AB, Biology and Government, Smith College

SM, Environmental Health (Environmental Epidemiology), Harvard School of Public Health

ScD, Environmental Health (Environmental Epidemiology), Harvard School of Public Health