7th Annual JBL Symposium
“Genetic Stability through Quality Control in Cellular Process”
November 5-6, 2004
Friday, November 5, 2004
WELCOME AND INTRODUCTIONS Dr. Bruce Demple Harvard School of Public Health |
SESSION I: SIGNALING |
DISCUSSION LEADER: Dr. William A. Toscano University of Minnesota School of Public Health |
Dr. James A. DeCaprio Dana-Farber Cancer Institute, Harvard Medical School “The ATR Kinase and the DNA Damage Response” |
Dr. Michael Yaffe Massachusetts Institute of Technology “Phospho-Serine/Threonine-Binding Domains are Molecular Integrators of Cell Cycle Kinases and DNA Damage Responses” |
Dr. Mary Ellen Perry National Institutes of Health, National Cancer Institute “Regulation of p53 by Mdm2” |
Dr. Mats Ljungman University of Michigan Comprehensive Cancer Center “Role of Transcription in the Activation of DNA Damage Signaling” |
Dr. Albert J. Fornace, Jr. National Institutes of Health, National Cancer Institute “Global Analysis of Molecular Responses to Stress with “-omic” Approaches: the Search for Agent-Specific Signatures for Radiation and other Genotoxic Agents” |
Saturday, November 6, 2004
SESSION II: CANCER |
DISCUSSION LEADER: Dr. Amy Kronenberg Lawrence Berkeley National Laboratory |
Dr. Gerard I. Evan University of California San Francisco “The Role of Ontogenesis and Tumor Suppressors in Tumor Maintenance” |
Dr. Zhi-Min Yuan Harvard School of Public Health “Oncogenic Effects of Low-Dose Ionizing Radiation-induced Premature Senescence in Stromal Fibroblasts; a Three Dimension Co-Culture Study” |
Dr. Yusaku Nakabeppu Kyushu University, Japan “Defenses against Oxidative Damage in Nucleic Acids and the Suppression of Carcinogenesis and Neurodegeneration” |
Dr. Aziz Sancar University of North Carolina at Chapel Hill School of Medicine “Circadian Cycle, Cell Cycle Checkpoints and Cancer” |
SESSION III: REPAIR |
DISCUSSION LEADER: Dr. John B. Little Harvard School of Public Health |
Dr. Patrick Sung Yale University “Mechanism of the Rad51 and Dmc1 Recombinases” |
Dr. Roger Woodgate National Institutes of Health, National Institute of Child Health and Human Development “Y-family DNA Polymerases and their Role in Maintaining Genomic Integrity” |
Dr. Nancy Maizels University of Washington “Mutagenic Pathways of Repair in the Immune Response” |
Dr. Bruce Demple Harvard School of Public Health “Life and Death: Ape1 Protein and Endogenous DNA Damage” |