JBL X: Nov. 2007

10th Annual John B. Little Symposium

“Cancer Stem Cells, Radiotherapy, and Modulation by Cellular Responses”

November 2-3, 2007


Friday, November 2, 2007

John B. Little Award Lecture given by Allan Balmain, Ph.D.

Barbara Bass Bakar Endowed Chair in Cancer Genetics

University of California, San Francisco

“Genetic networks and control of cancer susceptibility”

Charlotte Kuperwasser, Ph.D.

Assistant Professor of Anatomy and Cellular Biology

Tufts University School of Medicine

“The contribution and role of the stromal microenvironment on breast cancer stem cells”

Haifan Lin, Ph.D.

Director, Yale Stem Cell Center; Professor of Cell Biology

Yale University

“Stem cells, small RNAs, and self-renewal”

Paul Russell, Ph.D.


The Scripps Research Institute

“Cell cycle governance of double-strand break repair”

Pier Paolo Pandolfi, M.D., Ph.D., 

Professor; Associate Director, Beth Israel Deaconess Cancer Center; Chief, Division of Genetics

Beth Israel Deaconess Medical Center

“Pro-senescence therapy for cancer”

Frank McKeon, Ph.D.

Professor of Cell Biology

Harvard Medical School

“My brother thinks he’s a chicken: p63 as guardian of the female germline”

Norman Sharpless, M.D.

Assistant Professor, Lineberger Comprehensive Cancer Center

University of North Carolina

“Ink4α/Arf, senescence and stem cells”

Scott Armstrong, M.D., Ph.D.

Assistant Professor of Pediatrics

Children’s Hospital, Harvard Medical School

“Cellular origins of leukemia stem cells”

Alea Mills, Ph.D.

Associate Professor

Cold Spring Harbor Laboratory

“From chromosome engineering to chromatin remodeler: CHD5 is a tumor suppressor at human 1p36

Stewart Shuman, M.D., Ph.D.

Memorial Sloan-Kettering Cancer Center

“RNA repair”

Michael Yaffe, Ph.D., M.D.

Associate Professor of Biology

Massachusetts Institute of Technology

“A systems biology approach to DNA damage signaling”

Kornelia Polyak, M.D., Ph.D.

Associate Professor of Medicine

Dana-Farber Cancer Institute, Harvard Medical School

“Molecular definition of breast tumor heterogeneity”