JBL XII: Oct. 2009

12th Annual JBL Symposium

“Cellular Responses to Molecular Damage: Roles in Genetic Stability, Radioresistance, and Aging”

October 23-24, 2009

Matthew Meselson

Thomas Dudley Cabot Professor of the Natural Sciences, Department of Molecular and Cellular Biology, Harvard University

JBL Award Lecture: “How does ionizing radiation kill cells: early clues from bystander effects”

Stephen P. Bell

Professor of Biology, Massachusetts Institute of Technology, Investigator, Howard Hughes Medical Institute

“Triggering replication initiation: a cascade of kinases at the origin”

Junjie Chen

Professor, M.D. Anderson Cancer Center, Department of Experimental Radiation Oncology, University of Texas

“Chromatin structure and DNA damage response”

 Michael J. Daly

Professor of Pathology, Department of Pathology, Uniformed Service University of the Health Sciences

“Small molecule proteome-shields in Deinococcus radiodurans”

Anindya Dutta

Harry F. Byrd Professor, Department of Biochemistry and Molecular Genetics, University of Virginia

“Mechanisms by which the human cell restricts DNA replication to once per cell cycle”

Toren Finkel

Chief, Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health

“Mitochondrial function and oxidative stress in stem and progenitor cell function”

Marcia Haigis

Assistant Professor, Department of Pathology, Harvard Medical School

“Roles of Sirtuins in Mitochondrial Metabolism”

Wade Harper

Professor of Pathology, Department of Pathology, Harvard Medical School

“The SLX4 complex, a tool kit for DNA repair”

 Ursula Jakob

Associate Professor, Department of Molecular, Cellular, and Developmental Biology,

University of Michigan 

“Oxidative stress and redox regulation”

Penny Jeggo

Professor, Genome Damage and Stability Centre, University of Sussex

“ATM, higher order chromatin structure and DNA double strand break repair: how they link”

Laura Niedernhofer

Associate Professor, Department of Microbiology and Molecular Genetics, University of Pittsburgh

“Therapeutic strategies for delaying aging”

Lee Zou

Assistant Professor of Pathology, Harvard Medical School / Massachusetts General Hospital Cancer Center

“Sensing and signaling DNA damage through the ATM and ATR checkpoints”