JBL XV: Oct 2012

Welcome, Gökhan Hotamisligil, M.D., Ph.D.

Introduction, John B. Little. M.D.

Opening Remarks, Dean Julio Frenk

David H. Koch Professor of Biology and Biological Engineering, MIT

Alan D. D’Andrea, M.D. 

Alvan T. and Viola D. Fuller American Cancer Society Professor of Radiation Oncology, Department of Radiation Oncology, Harvard Medical School; Scientific Director, Molecular Diagnostics Laboratory, Dana-Farber Cancer Institute

“Targeting the Fanconi Anemia/BRCA Pathway in Cancer Therapy”

Martin Brown, Ph.D.

Professor, Radiation Oncology – Radiation and Cancer Biology, Stanford University

“Circulating normal cells affect tumor radiosensitivity”

Hilary A. Coller, Ph.D.

Assistant Professor of Molecular Biology, Princeton University

“Sleeper Cells: The Secret Life of Quiescent Fibroblasts”

Tak W. Mak, Ph.D.

Director, Advanced Medical Discovery Institute; Director, The Campbell Family Institute for Breast Cancer Research; Senior Scientist, Division of Stem Cell and Developmental Biology; Advanced Medical Discovery Institute/Ontario Cancer Institute

“Metabolic Adaptation in Cancer Cells”

Anita Hjelmeland, Ph.D.

Assistant Professor of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University

“Understanding and Targeting Microenvironmental Influences on the Glioma Stem Cell Phenotype”

William Matsui, M.D.

Associate Professor of Oncology, Johns Hopkins University School of Medicine; The Sidney Kimmel Comprehensive Cancer

“Translating the cancer stem cell hypothesis from the lab to the clinic”

Brendan Manning, Ph.D.

Associate Professor of Molecular Metabolism, Department of Molecular Metabolism, Harvard School of Public Health

“Linking oncogenic signaling to anabolic metabolism through mTOR”

M. Celeste Simon, Ph.D.

Professor of Cell and Developmental Biology, University of Pennsylvania, Howard Hughes Medical Institute, The Abramson Family Cancer Research Institute

“Hypoxia, Metabolism, and Tumor Progression”

Head of Research, Chromosome Biology Unit, Danish Cancer Society Research Centre; Centre for Genotoxic Stress Research

“Reprogramming the epigenome by DNA damage”

David W. Wallace Professor of Immunobiology, Yale School of Medicine; Investigator, Howard Hughes Medical Institute

“Accessory functions of macrophages in tumor development”

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center