Julie Goodman

Adjunct Lecturer on Epidemiology

Department of Epidemiology

Kresge Bldg, 9th Floor
677 Huntington Avenue
Boston, Massachusetts 02115

Other Affiliation

Principal, Gradient


Julie Goodman is an epidemiologist and board-certified toxicologist at Gradient, an environmental consulting firm.  Her responsibilities at Gradient include the design, oversight, analysis, and interpretation of epidemiology studies, and the evaluation of chemical toxicology data, apparent disease clusters, and chemical exposures.  She assesses human health risks based on weight-of-evidence analyses of epidemiology and toxicology data, and she communicates her findings to scientific and non-scientific audiences.  Dr. Goodman’s areas of expertise include occupational exposures, air pollutants, product safety, and carcinogenesis.  She is co-instructing “Research Synthesis & Meta-Analysis” at the Harvard School of Public Health.


  • Ph.D., Johns Hopkins Bloomberg School of Public Health
  • Sc.M., Johns Hopkins Bloomberg School of Public Health
  • S.B., Massachusetts Institute of Technology
  • Diplomate, American Board of Toxicology (DABT)
  • Fellow, American College of Epidemiology (ACE)
  • Fellow, Academy of Toxicological Sciences (ATS)

Selected Publications

Kerper, LE; Lynch, HN; Zu, K; Tao, G; Utell, MJ; Goodman, JE. 2014. “Systematic Review of Pleural Plaques and Lung Function.” Inhal. Toxicol. 18:1-30.

Goodman, JE; Prueitt, RL; Sax, SN; Lynch, HN; Zu, K; Lemay, JC; King, JM; Venditti, FJ. 2014. “Weight-of-evidence Evaluation of Short-term Ozone Exposure and Cardiovascular Effects.” Crit. Rev. Toxicol. 44(9):725-790.

Prueitt, RL; Lynch, HN; Zu, K; Sax, SN; Venditti, FJ; Goodman, JE. 2014. “Weight-of-evidence Evaluation of Long-term Ozone Exposure and Cardiovascular Effects.” Crit. Rev. Toxicol. 44(9):791-822.

Lamb, JC; Boffetta, P; Foster, WG; Goodman, JE; Hentz, KL; Rhomberg, LR; Staveley, J; Swaen, G; Van Der Kraak, G; Williams, AL. 2014. “Critical Comments on the WHO-UNEP State of the Science of Endocrine Disrupting Chemicals – 2012.” Reg. Tox. Pharm. 69(1):22-40.

Keum, N; Woong, J; Hoon Lee, D; Ding, EL; Hsieh, CC; Goodman, JE; Giovannucci, EL. 2014. “Leisure-Time Physical Activity and Endometrial Cancer Risk: Dose-Response Meta-Analysis of Epidemiological Studies.” Int. J. Cancer. 135(3):682-94. doi: 10.1002/ijc.28687.

Clark, K; Flynn, J; Goodman, JE; Zu, K; Karmaus, W; Mohr, L. 2014. “Pleural Plaques and their Effect on Lung Function in Libby Vermiculite Miners.” CHEST. doi: 10.1378/chest.14-0043.

Goodman, JE; Prueitt, RL; Chandalia, J; Sax, SN. 2014. “Evaluation of Adverse Human Lung Function Effects in Controlled Ozone Exposure Studies.” J. Appl. Toxicol. 34(5):516-524.

Goodman, JE; Petito Boyce, C; Pizzurro, DM; Rhomberg, LR. 2014. “Strengthening the Foundation of Next Generation Risk Assessment.” Reg. Tox. Pharmacol. 68(1):160-170.

Goodman, JE; Peterson, MK; Bailey, LA; Kerper, LE; Dodge, DG. 2014. “Electricians’ Chrysotile Asbestos Exposure from Electrical Products and Risks of Mesothelioma and Lung Cancer.” Reg. Tox. Pharmacol. 68(1):8-15.

Rhomberg, LR; Goodman, JE; Bailey, LA; Prueitt, RL; Beck, NB; Bevan, C; Honeycutt, M; Kaminski, NE; Paoli, G; Pottenger, LH; Scherer, RW; Wise, KC; Becker, RA. 2013. “A Survey of Frameworks for Best Practices in Weight-of-Evidence Analyses.” Crit. Rev. Toxicol. 43(9):753-784.

Goodman, JE; Prueitt, RL; Sax, SN; Bailey, LA; Rhomberg, LR. 2013. “Evaluation of the Causal Framework Used for Setting National Ambient Air Quality Standards.” Crit. Rev. Toxicol. 43(10):829-849.

Prueitt, RL; Rhomberg, LR; Goodman, JE. 2013. “Hypothesis-Based Weight-of-Evidence Evaluation of the Human Carcinogenicity of Toluene Diisocyanate.” Crit. Rev. Toxicol. 43(5):391-435.

Rhomberg, LR; Goodman, JE. 2012. “Low-Dose Effects and Nonmonotonic Dose-Responses of Endocrine Disrupting Chemicals: Has the Case Been Made?” Reg. Tox. Pharmacol. 64(1):130-133.

Prueitt, RL; Goodman, JE; Bailey, LA; Rhomberg, LR. 2011. “Hypothesis-based weight-of-evidence evaluation of the neurodevelopmental effects of chlorpyrifos.” Crit. Rev. Toxicol. 41(10):822-903.

Rhomberg, LR; Chandalia, JK; Long, CM; Goodman, JE. 2011. “Measurement error in environmental epidemiology and the shape of exposure-response curves.” Crit. Rev. Toxicol. 41(8):651-671.

Goodman, JE; Prueitt, RL; Thakali, S; Oller, AR. 2011. “The nickel ion bioavailability model of the carcinogenic potential of nickel-containing substances in the lung.” Crit. Rev. Toxicol. 41:142-174.

Rhomberg, LR; Goodman, JE; Haber, LT; Dourson, M; Andersen, ME; Klaunig, JE; Meek, B; Price, PS; McClellan, RO; Cohen, SM. 2011. “Linear low-dose extrapolation for non-cancer health effects is the exception, not the rule.” Crit. Rev. Toxicol. 41(1):1-19.

Rhomberg, LR; Bailey, LA; Goodman, JE; Hamade, AK; Mayfield, DB. 2011. “Is exposure to formaldehyde in air causally associated with leukemia? – A hypothesis-based weight-of-evidence analysis.” Crit. Rev. Toxicol. 41(7):555-621.

Goodman, JE; Dodge, DG; Bailey, LA. 2010. “A framework for assessing causality and adverse effects in humans with a case study of sulfur dioxide.” Reg. Tox. Pharmacol. 58:308-322.

Goodman, JE; Kerper, LE; Petito Boyce, C; Prueitt, RL; Rhomberg, LR. 2010. “Weight-of-evidence analysis of human exposures to dioxins and dioxin-like compounds and thyroid hormone levels during early development.” Reg. Tox. Pharmacol. 58(1):79-99.

Goodman, JE; Hudson, TC; Monteiro, RJ. 2010. “Cancer cluster investigation in residents near a municipal landfill.” Hum. Ecol. Risk Assess. 16(6):1339-1359.

Goodman, JE; Nascarella, MA; Valberg, PA. 2009. “Ionizing radiation: A risk factor for mesothelioma.” Cancer Causes and Control. 20:1237-1254.

Goodman, JE; Prueitt, RL; Dodge, DG; Thakali, S. 2009. “Carcinogenicity assessment of water-soluble nickel compounds.” Crit. Rev. in Toxicol. 39(5):365-417.

Goodman, JE; Chandalia, JK; Thakali, S; Seeley, M. 2009. “Meta-analysis of nitrogen dioxide exposure and airway hyper-responsiveness in asthmatics.” Crit. Rev. Toxicol. 39(9):719-742.

Goodman, JE; Prueitt, RL; Dodge, DG; Thakali, S. 2009. “Carcinogenicity assessment of water-soluble nickel compounds.” Crit. Rev. in Toxicol.  39(5):365-417.

Bailey, LA; Goodman, JE, Beck BD.  2009.  “Proposal for a revised Reference Concentration (RfC) for manganese based on recent epidemiological studies.” Regul. Toxicol. Pharmacol. 55(3): 330-339.

Goodman, JE; Nascarella, MA; Valberg, PA. 2009. “Ionizing radiation: A risk factor for mesothelioma.” Cancer Causes and Control 20:1237-1254.

Goodman, JE. 2009. “Neurodevelopmental effects of decabromodiphenyl ether (BDE-209) and implications for the reference dose.” Reg. Tox. and Pharmacol. 54(1):91-104.

Petito Boyce, C; Sax, SN; Dodge, DG; Pollock, MC; Goodman, JE. 2009.  “Human exposure to decabromodiphenyl ether, tetrabromobisphenol a, and decabromodiphenyl ethane in indoor dust.” J. Environ. Protection Sci. 3:75-96.

Goodman, JE; Witorsch, RJ; McConnell, EE; Sipes, IG; Slayton, TM; Yu, CJ; Franz, AM; Rhomberg, LR. 2009. “Weight-of-evidence evaluation of reproductive and developmental effects of low doses of bisphenol A.” Crit. Rev. in Toxicol. 39(1):1-75.

Prueitt, RL; Goodman, JE; Valberg, PA. 2009. “Radionuclides in cigarettes may lead to carcinogenesis via p16INK4a inactivation.” J. of Environ. Radioactivity 100(2):157-161.

Goodman, JE; Gaylor, D; Beyer, LA; Rhomberg, LR; Beck, BD. 2008. “Effects of MTBE on the reported incidence of Leydig cell tumors in Sprague-Dawley rats: Range of possible Poly-3 results.” Regul. Toxicol. Pharmacol. 50: 273-284.