Assistant Professor of Medicine
Medicine-Brigham and Women's Hospital
Harvard Medical School
As an epidemiologist with medical training, Dr. Li is experienced and committed to the research of diabetes and cardiovascular disease prevention, with particular interests and expertise in integrating state-of-the-art multi-omics technologies and advanced analytics under the framework of systems epidemiology, aiming to identify novel risk factors, understand disease etiology and mechanisms through which risk factors impact health, and to inform the development of personalized preventive and therapeutic strategies. In the past few years, Dr. Li has been leading multiple projects in large population cohorts and interventional trials including the UK Biobank, Nurses’ Health Studies, Health Professionals Follow-up Study, the PREDIMED study, and the Hispanic Community Health Study/Study of Latinos, among others. Dr. Li was awarded the Jeremiah and Rose Stamler Research Award and the Mark Bieber Award by the American Heart Association. She is actively involved in teaching activities at the Harvard T.H. Chan School of Public Health. Her current research projects include:
1. integrating multi-omics data (transcriptomics, metabolomics, and metagenomics) to examine mechanisms through which diet and lifestyles affect risk of cardiovascular disease, diabetes, and cognitive decline;
2. employing large-scale genetic, transcriptomic, and proteomic data to examine biological risk factors and pathways relevant to the development cardiovascular disease and diabetes;
3. using polygenic risk prediction for complex disease to identify high-risk populations and examine effective diet/lifestyle intervention strategies for disease prevention among high genetic risk groups.
Postdoc fellow, 01/2020, Cardiometabolic Disease Epidemiology, Integrated Omics
Harvard T.H. Chan School of Public Health, Boston, MA
Research Scientist, 03/2022, Cardiometabolic Disease Epidemiology, Integrated Omics
Harvard T.H. Chan School of Public Health, Boston, MA
MD, 06/2011, Preventive Medicine
Tongji Medical College, Huazhong University of Science and Technology, China
PhD, 06/2016, Cardiovascular Epidemiology and Environmental Health
School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, China
The Mark Bieber Award
American Heart Association
Scott Grundy Fellowship Award for Excellence in Metabolism Research
American Heart Association
The “Reviewers’ Choice” Award
American Society of Human Genetics Annual Meeting
The Jeremiah and Rose Stamler Research Award winner
American Heart Association
The Barry R. and Irene Tilenius Bloom Fellowship Award
Harvard T.H. Chan School of Public Health
The Postdoc Association Travel Award
Harvard T.H. Chan School of Public Health
Best Young Investigators
The Lancet-CAMS Health Summit 2015
The Bernard Lown Scholarship in Cardiovascular Health Program
Harvard T. H. Chan School of Public Health
Hu J, Xu X, Li J, Jiang Y, Hong X, Rexrode KM, Wang G, Hu FB, Zhang H, Karmaus WJ, Wang X, Liang L.
Clin Epigenetics. 2023 03 25. 15(1):51. PMID: 36966332
Han X, Zhu Z, Xiao Q, Li J, Hong X, Wang X, Hasegawa K, Camargo CA, Liang L.
Commun Biol. 2022 10 17. 5(1):1098. PMID: 36253437
Goni L, Razquin C, Toledo E, Guasch-Ferré M, Clish CB, Babio N, Wittenbecher C, Atzeni A, Li J, Liang L, Dennis C, Alonso-Gómez Á, Fitó M, Corella D, Gómez-Gracia E, Estruch R, Fiol M, Lapetra J, Serra-Majem L, Ros E, Arós F, Salas-Salvadó J, Hu FB, Martínez-González MA, Ruiz-Canela M.
Am J Clin Nutr. 2022 09 02. 116(3):653-662. PMID: 35575609
Hu J, Yao J, Deng S, Balasubramanian R, Jiménez MC, Li J, Guo X, Cruz DE, Gao Y, Huang T, Zeleznik OA, Ngo D, Liu S, Rosal MC, Nassir R, Paynter NP, Albert CM, Tracy RP, Durda P, Liu Y, Taylor KD, Johnson WC, Sun Q, Rimm EB, Eliassen AH, Rich SS, Rotter JI, Gerszten RE, Clish CB, Rexrode KM.
Circ Res. 2022 Sep 16. 131(7):601-615. PMID: 36052690
Chai JC, Chen GC, Yu B, Xing J, Li J, Khambaty T, Perreira KM, Perera MJ, Vidot DC, Castaneda SF, Selvin E, Rebholz CM, Daviglus ML, Cai J, Van Horn L, Isasi CR, Sun Q, Hawkins M, Xue X, Boerwinkle E, Kaplan RC, Qi Q.
Diabetes. 2022 06 01. 71(6):1338-1349. PMID: 35293992
Haslam DE, Li J, Dillon ST, Gu X, Cao Y, Zeleznik OA, Sasamoto N, Zhang X, Eliassen AH, Liang L, Stampfer MJ, Mora S, Chen ZZ, Terry KL, Gerszten RE, Hu FB, Chan AT, Libermann TA, Bhupathiraju SN.
Proteomics. 2022 07. 22(13-14):e2100170. PMID: 35598103
Merino J, Guasch-Ferré M, Li J, Chung W, Hu Y, Ma B, Li Y, Kang JH, Kraft P, Liang L, Sun Q, Franks PW, Manson JE, Willet WC, Florez JC, Hu FB.
PLoS Med. 2022 04. 19(4):e1003972. PMID: 35472203
Wang F, Baden MY, Guasch-Ferré M, Wittenbecher C, Li J, Li Y, Wan Y, Bhupathiraju SN, Tobias DK, Clish CB, Mucci LA, Eliassen AH, Costenbader KH, Karlson EW, Ascherio A, Rimm EB, Manson JE, Liang L, Hu FB.
Diabetologia. 2022 07. 65(7):1119-1132. PMID: 35391539
Chen GC, Chai JC, Xing J, Moon JY, Shan Z, Yu B, Mossavar-Rahman Y, Sotres-Alvarez D, Li J, Mattei J, Daviglus ML, Perkins DL, Burk RD, Boerwinkle E, Kaplan RC, Hu FB, Qi Q.
Diabetologia. 2022 07. 65(7):1133-1144. PMID: 35357561
Li Y, Wang F, Li J, Ivey KL, Wilkinson JE, Wang DD, Li R, Liu G, Eliassen HA, Chan AT, Clish CB, Huttenhower C, Hu FB, Sun Q, Rimm EB.
BMC Microbiol. 2022 03 29. 22(1):82. PMID: 35350985
A new Harvard Chan School study has identified a group of metabolites associated with risk of mortality, and another group linked with longevity.
Newly identified “metabolic signature” can evaluate an individual’s adherence to Mediterranean diet and help predict future risk of CVD.
Both rotating night shift work and an unhealthy lifestyle are linked with increased risk of type 2 diabetes in women, according to a new study from Harvard T.H. Chan School of Public Health. But when both factors are…