Technician, 2016 – Present
Undergraduate Degree: Boston University
Cameron’s Publications from the Sarosiek Laboratory:
| AI is a viable alternative to high throughput screening: a 318-target study. Kristopher Sarosiek, Adam Presser, Xingping Qin, Zintis Inde, Cameron Fraser. Scientific Reports, 2024 April 02. PubMed. External. |
 Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX.Rumani Singh, Stacey Yu, Marwa Osman, Zintis Inde, Cameron Fraser, Abigail Cleveland, Nicole Almanzar, Chuan Bian Lim, Gaurav Joshi, Johan Spetz, Xingping Qin, Sneh Toprani, Zachary Nagel, Matthew C Hocking, Robert A Cormack, Torunn I Yock, Jeffrey W Miller, Zhi-Min Yuan, Timothy Gershon, Kristopher Sarosiek. Cancer Research, 2023 October 13. PDF. External. |
 Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy–induced toxicities.Johan Spetz, Kiwi Florido, Cameron Fraser, Xingping Qin, Jonathan Choiniere, Stacey Yu, Rumani Singh, Max Friesen, Lee L. Rubin, Joe-Elie Salem, Javid J. Moslehi, Kristopher Sarosiek. Science Advances, 2022 November 11. PDF. External. |
| Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex. Molly C McNamara, Aaron M Hosios, Margaret E Torrence, Ting Zhao, Cameron Fraser, Meghan Wilkinson, David J Kwiatkowski, Elizabeth P Henske, Chin-Lee Wu, Kristopher Sarosiek, Alexander J Valvezan, Brendan D Manning iScience, 2022 October 28. External. |
 Exploiting endogenous and therapy-induced apoptotic vulnerabilities in immunoglobulin light chain amyloidosis with BH3 mimetics.Cameron Fraser, Johan Spetz, Xingping Qin, Adam Presser, Jonathan Choiniere, Chendi Li, Stacey Yu, Frances Blevins, Aaron N. Hata, Jeffrey W. Miller, Gary A. Bradshaw, Marian Kalocsay, Vaishali Sanchorawala, Shayna Sarosiek (co-corresponding author), Kristopher Sarosiek. Nature Communications, 2022 Oct 2. PDF. Pubmed. |
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A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer. Treg Grubb, Smruthi Maganti, John Michael Krill-Burger, Cameron Fraser, Laura Stransky, Tomas Radivoyevitch, Kristopher Sarosiek, Francisca Vazquez, William G. Kaelin, Jr, Abhishek A. Chakraborty. Clinical Cancer Research, 2022 Jul 1. PubMed. |
 Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity.Zintis Inde, Ben A. Croker (co-first author), Clarence Yapp, Gaurav Joshi, Johan Spetz, Cameron Fraser, Xingping Qin, Le Xu, Brian Deskin, Elisa Ghelfi, Gabrielle Webb, Aaron F. Carlin, Yangfei Peipei Zhu, Sandra Leibel, Aaron F. Garretson, Alex E. Clark, Jason M. Duran, Victor Pretorius, Laura E. Crotty-Alexander, Chendi Li, Jamie Casey Lee, Chhinder Sodhi, David J. Hackam, Xin Sun, Aaron Hata, Lester Kobzik, Jeffrey Miller, Jin-Ah Park, Douglas Brownfield, Hongpeng Jia, Kristopher A. Sarosiek. Science Advances, August 18, 2021. PDF. PubMed. |
 Zintis Inde, Clarence Yapp, Gaurav Joshi, Johan Spetz, Cameron Fraser, Brian Deskin, Elisa Ghelfi, Chhinder Sodhi, David J. Hackam, Lester Kobzik, Ben A. Croker, Douglas Brownfield, Hongpeng Jia, Kristopher A. Sarosiek. Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity (Preprint).BioRxiv, September 13, 2020. PDF. BioRxiv. |
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Chen Lossos, Yunpeng Liu, Kellie E. Kolb, Amanda L. Christie, Alexandria Van Scoyk, Sanjay M. Prakadan, Kay Shigemori, Kristen E. Stevenson, Sara Morrow, Olivia D. Plana, Cameron Fraser, Kristen L. Jones, Huiyun Liu, Christian P. Pallasch, Rebecca Modiste, Quang-De Nguyen, Jeffrey W. Craig, Elizabeth A. Morgan, Francisco Vega, Jon C. Aster, Kristopher A. Sarosiek, Alex K. Shalek, Michael T. Hemann and David M. Weinstock |
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Cameron Fraser, Adam Presser, Vaishali Sanchorawala, Shayna Sarosiek, Kristopher A. Sarosiek. Clonal plasma cells in AL amyloidosis are dependent on pro survival BCL-2 family proteins and sensitive to BH3 mimetics (Preprint). BioRxiv, February 6 2019. PDF. BioRxiv. |
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Varuna Nangia, Faria M Siddiqui, Sean Caenepeel, Daria Timonina, Samantha J Bilton, Nicole Phan, Maria Gomez-Caraballo, Hannah L Archibald, Chendi Li, Cameron Fraser, Diamanda Rigas, Kristof Vajda, Lorin A Ferris, Michael Lanuti, Cameron D Wright, Kevin A Raskin, Daniel P Cahill, John H Shin, Colleen Keyes, Lecia V. Sequist, Zofia Piotrowska, Anna F. Farago, Christopher G Azzoli, Justin F. Gainor, Kristopher Sarosiek, Sean P Brown, Angela Coxon, Cyril H. Benes, Paul E. Hughes and Aaron N. Hata. |
 Kristopher A. Sarosiek, Cameron Fraser, Nathiya Muthalagu, Patrick D. Bhola, Weiting Chang, Samuel K. McBrayer, Adam Cantlon, Sudeshna Fisch, Gail Golomb-Mello, Jeremy M. Ryan, Jing Deng, Brian Jian, Chris Corbett, Marti Goldenberg, Joseph R. Madsen, Ronglih Liao, Dominic Walsh, John Sedivy, Daniel J. Murphy, Daniel Ruben Carrasco, Shenandoah Robinson, Javid Moslehi, Anthony G. Letai.Developmental regulation of mitochondrial apoptosis by c-Myc governs age- and tissue-specific sensitivity to cancer therapeutics. Cancer Cell, 2017 Jan 9: 31(1):142-156. PDF. Supplemental Data. Pubmed. |
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Jan A. Burger, Dan A. Landau, Amaro Taylor-Weiner, Ivana Bozic, Huidan Zhang, Kristopher A. Sarosiek, Lili Wang, Chip Stewart, Jean Fan, Julia Hoellenriegel, Mariela Sivina, Adrian M. Dubuc, Cameron Fraser, Yulong Han, Shuqiang Li, Kenneth J. Livak, Lihua Zou, Youzhong Wan, Sergej Konoplev, Carrie Sougnez, Lynne V. Abruzzo, Scott L. Carter, Michael J. Keating, Matthew S. Davids, William G. Wierda, Kristian Cibulskis, Thorsten Zenz, Lillian Werner, Paola Dal Cin, Peter Kharchencko, Donna Neuberg, Hagop Kantarjian, Eric Lander, Stacey Gabriel, Susan O’Brien, Anthony Letai, David A. Weitz, Martin A. Nowak, Gad Getz, Catherine J. Wu. Clonal evolution in patients with chronic lymphocytic leukemia developing resistance to BTK inhibition. Nature Communications, 2016 May 20;7:11589. Pubmed. |
