Cameron Fraser

Technician, 2016 – Present

Undergraduate Degree: Boston University

Cameron’s Publications from the Sarosiek Laboratory:

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity.
Zintis Inde, Ben A. Croker (co-first author), Clarence Yapp, Gaurav Joshi, Johan Spetz, Cameron Fraser, Xingping Qin, Le Xu, Brian Deskin, Elisa Ghelfi, Gabrielle Webb, Aaron F. Carlin, Yangfei Peipei Zhu, Sandra Leibel, Aaron F. Garretson, Alex E. Clark, Jason M. Duran, Victor Pretorius, Laura E. Crotty-Alexander, Chendi Li, Jamie Casey Lee, Chhinder Sodhi, David J. Hackam, Xin Sun, Aaron Hata, Lester Kobzik, Jeffrey Miller, Jin-Ah Park, Douglas Brownfield, Hongpeng Jia, Kristopher A. Sarosiek.
Science Advances, August 18, 2021. PDF. PubMed.

Zintis Inde, Clarence Yapp, Gaurav Joshi, Johan Spetz, Cameron Fraser, Brian Deskin, Elisa Ghelfi, Chhinder Sodhi, David J. Hackam, Lester Kobzik, Ben A. Croker, Douglas Brownfield, Hongpeng Jia, Kristopher A. Sarosiek. Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity (Preprint).
BioRxiv, September 13, 2020. PDF. BioRxiv.

Chen Lossos, Yunpeng Liu, Kellie E. Kolb, Amanda L. Christie, Alexandria Van Scoyk, Sanjay M. Prakadan, Kay Shigemori, Kristen E. Stevenson, Sara Morrow, Olivia D. Plana, Cameron Fraser, Kristen L. Jones, Huiyun Liu, Christian P. Pallasch, Rebecca Modiste, Quang-De Nguyen, Jeffrey W. Craig, Elizabeth A. Morgan, Francisco Vega, Jon C. Aster, Kristopher A. Sarosiek, Alex K. Shalek, Michael T. Hemann and David M. Weinstock
Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents.
Cancer Discovery, 2019 April 30. Pubmed.

Cameron Fraser, Adam Presser, Vaishali Sanchorawala, Shayna Sarosiek, Kristopher A. Sarosiek.
Clonal plasma cells in AL amyloidosis are dependent on pro survival BCL-2 family proteins and sensitive to BH3 mimetics (Preprint).
BioRxiv, February 6 2019. PDF. BioRxiv.

Cameron Fraser, Jeremy Ryan, Kristopher A. Sarosiek.
BH3 Profiling: A Functional Assay to Measure Apoptotic Priming and Dependencies (Protocol).
Methods in Molecular Biology, January 2019;1877:61-76. PDF. Pubmed.

Varuna Nangia, Faria M Siddiqui, Sean Caenepeel, Daria Timonina, Samantha J Bilton, Nicole Phan, Maria Gomez-Caraballo, Hannah L Archibald, Chendi Li, Cameron Fraser, Diamanda Rigas, Kristof Vajda, Lorin A Ferris, Michael Lanuti, Cameron D Wright, Kevin A Raskin, Daniel P Cahill, John H Shin, Colleen Keyes, Lecia V. Sequist, Zofia Piotrowska, Anna F. Farago, Christopher G Azzoli, Justin F. Gainor, Kristopher Sarosiek, Sean P Brown, Angela Coxon, Cyril H. Benes, Paul E. Hughes and Aaron N. Hata.
Exploiting MCL-1 dependency with combination MEK + MCL-1 inhibitors leads to induction of apoptosis and tumor regression in KRAS mutant non-small cell lung cancer.
Cancer Discovery, 2018 Sep 25. Pubmed.

Kristopher A. Sarosiek, Cameron Fraser, Nathiya Muthalagu, Patrick D. Bhola, Weiting Chang, Samuel K. McBrayer, Adam Cantlon, Sudeshna Fisch, Gail Golomb-Mello, Jeremy M. Ryan, Jing Deng, Brian Jian, Chris Corbett, Marti Goldenberg, Joseph R. Madsen, Ronglih Liao, Dominic Walsh, John Sedivy, Daniel J. Murphy, Daniel Ruben Carrasco, Shenandoah Robinson, Javid Moslehi, Anthony G. Letai.
Developmental regulation of mitochondrial apoptosis by c-Myc governs age- and tissue-specific sensitivity to cancer therapeutics.
Cancer Cell, 2017 Jan 9: 31(1):142-156. PDF. Supplemental Data. Pubmed.
Jan A. Burger, Dan A. Landau, Amaro Taylor-Weiner, Ivana Bozic, Huidan Zhang, Kristopher A. Sarosiek, Lili Wang, Chip Stewart, Jean Fan, Julia Hoellenriegel, Mariela Sivina, Adrian M. Dubuc, Cameron Fraser, Yulong Han, Shuqiang Li, Kenneth J. Livak, Lihua Zou, Youzhong Wan, Sergej Konoplev, Carrie Sougnez, Lynne V. Abruzzo, Scott L. Carter, Michael J. Keating, Matthew S. Davids, William G. Wierda, Kristian Cibulskis, Thorsten Zenz, Lillian Werner, Paola Dal Cin, Peter Kharchencko, Donna Neuberg, Hagop Kantarjian, Eric Lander, Stacey Gabriel, Susan O’Brien, Anthony Letai, David A. Weitz, Martin A. Nowak, Gad Getz, Catherine J. Wu.
Clonal evolution in patients with chronic lymphocytic leukemia developing resistance to BTK inhibition.
Nature Communications, 2016 May 20;7:11589. Pubmed.