Lidia Mínguez-Alarcón

Senior Research Scientist

Department of Environmental Health


With joint appointments both at the Harvard Medical School/Brigham and Women’s Hospital as well as the Harvard TH Chan School of Public Health, Dr. Mínguez-Alarcón’s research focuses on identifying chemical and non-chemical stressors of human fertility, reproductive and cardiometabolic health. She is also evaluating fertility measures as predictors of long-term health. As an environmental and reproductive epidemiologist, she is primarily working in the EARTH Study, a prospective cohort study of subfertile couples at the MGH fertility center in Boston. She is also an active collaborator in the Russian Children’s Study, PEACE Study, Project Viva, NHS2, NHS3 and VDAART. Dr. Mínguez-Alarcón is the PI of the recently NIH funded Longitudinal Investigation of Health and Diseases after Infertility (LIHDI) Study, which will re-enroll former female EARTH participants to assess their health at midlife. She will prospectively explore chemical exposures during reproductive years in relation to long-term cardiovascular and metabolic health and whether fertility measures mediate the associations. She brings her expertise to the Science of the Total Environment (STOTEN) journal as an Associate Editor.


Ph.D., University of Murcia School of Medicine

M.P.H., University of Murcia School of Medicine

B. Pharm., University of Valencia School of Pharmacy


Selected publications

Mínguez-Alarcón L, Mendiola J, López-Espín JJ, Sarabia-Cos L, Vivero-Salmerón G, Vioque J, Navarrete-Muñoz EM, Torres-Cantero AM. Dietary intake of antioxidant nutrients is associated with semen quality in young university students. Hum Reprod. 2012 Sep;27(9):2807-14.

Mínguez-Alarcón L, Gaskins AJ, Chiu Y-H, Souter I, Williams PL, Hauser R, Chavarro J, for the Earth Study Team. Dietary folate intake and modification of the association of urinary bisphenol A concentrations with in vitro fertilization outcomes among women from a fertility clinic. Reprod Toxicol. 2016 Jul 14;65:104-112.

Mínguez-Alarcón L, Sergeyev O, Burns JS, Williams PL, Lee MM, Korrick SA, Smigulina L, Revich B, Hauser R. A longitudinal study of peripubertal serum organochlorine concentrations and semen parameters in young men: The Russian Children’s Study. Environ Health Perspect. 2017 Mar;125(3):460-466.

Mínguez-Alarcón L, Souter I, Williams PL, Ford JB, Hauser R, Chavarro J, Gaskins AJ, for the Earth Study Team. Occupational factors and markers of ovarian reserve and response among women at a fertility center. Occup Environ Med. 2017 Jun;74(6):426-431.

Mínguez-Alarcón L, Gaskins AJ, Chiu YH, Messerlian C, Williams PL, Ford JB, Souter I, Hauser R, Chavarro JE. Type of underwear worn and markers of testicular function among men attending a fertility center. Hum Reprod. 2018 Sep 1;33(9):1749-1756.

Mínguez-Alarcón L, Williams PL, Chiu YH, Gaskins AJ,  Nassan FL,  Dadd R, Petrozza J, Hauser R, Chavarro JE. Secular trends in semen parameters among men attending a fertility center between 2000 and 2017: Identifying potential predictors. Environ Int. 2018 Dec;121:1297-1303.

Ghayda RA, Williams PL, Chavarro JE, Ford J, Souter I,Calafat AM, Hauser R, Mínguez-Alarcón L. Urinary bisphenol S concentrations: Potential predictors of and associations with semen quality parameters among men attending a fertility center. Environ Int. 2019 Oct;131:105050.

Souter I, Bellavia A, Williams PL, Korevaar TIM, Meeker JD, Braun JM, de Poortere RA, Broeren MA, Ford JB, Calafat AM, Chavarro JE, Hauser R, Mínguez-Alarcón L; Earth Study Team. Urinary Concentrations of Phthalate Metabolite Mixtures in Relation to Serum Biomarkers of Thyroid Function and Autoimmunity among Women from a Fertility Center.  Environ Health Perspect. 2020 Jun;128(6):67007.

Mínguez-Alarcón L, Bellavia A, Gaskins AJ, Chavarro JE, Ford JB, Souter I, Calafat AM, Hauser R, Williams PL; EARTH Study Team. Paternal mixtures of urinary concentrations of phthalate metabolites, bisphenol A and parabens in relation to pregnancy outcomes among couples attending a fertility center. Environ Int. 2021 Jan;146:106171.

Mínguez-Alarcón L, Rifas-Shiman SL, Sordillo JE, Aris IM, Wu AJ, Hivert MF, Oken E, Chavarro JE. Association of Mode of Obstetric Delivery With Child and Adolescent Body Composition. JAMA Netw Open. 2021 Oct 1;4(10):e2125161.

Wang YX, Mínguez-Alarcón L, Gaskins AJ, Wang L, Ding M, Missmer SA, Rich-Edwards JW, Manson JE, Chavarro JE. Pregnancy loss and risk of cardiovascular disease: the Nurses’ Health Study II. Eur Heart J. 2021  Online ahead of print.