Manja Koch

Research Associate

Department of Nutrition

655 Huntington Avenue, Building 2
Room 309

Boston, MA 02115


My research agenda centers on the identification of risk factors for cardiometabolic disorders and dementia. My current work focuses on the role of diet, apolipoproteins, and sphingolipids in dementia risk in the Ginkgo Evaluation of Memory Study and the Cardiovascular Health Study.


Dr. oec. troph. (Ph.D. equivalent), 2013, Nutrition Science, University of Kiel, Germany

M.Sc., 2013, Epidemiology, Gutenberg University Mainz, Germany

M.Sc., 2010, Nutrition Science, University of Kiel, Germany

B.Sc., 2007, Life Science, Leibniz University Hanover, Germany


2019-2021, Research Fellowship, Alzheimer’s Association

2015-2017, Postdoctoral Fellowship, German Research Foundation

Selected Publications

Koch M, Costanzo S, Fitzpatrick AL, Lopez OL, DeKosky ST, Kuller LH, Price J, Mackey RH, Jensen MK, Mukamal KJ. Alcohol consumption, brain amyloid β-deposition, and brain structural integrity among older adults free of dementia. J Alzheimers Dis. 2020. In press.

Koch M, DeKosky ST, Goodman M, Sun J, Furtado JD, Fitzpatrick AL, Mackey RH, Cai T, Lopez OL, Kuller LH, Mukamal KJ, Jensen MK. High-density lipoprotein and its apolipoprotein-defined subspecies and risk of dementia. J Lipid Res. 2019. In press.

Koch M, Fitzpatrick AL, Rapp SR, Nahin RL, Williamson JD, Lopez OL, DeKosky ST, Kuller LH, Mackey RH, Mukamal KJ, Jensen MK, Sink KM. Alcohol Consumption and Risk of Dementia and Cognitive Decline Among Older Adults With or Without Mild Cognitive Impairment. JAMA Netw Open. 2019;2:e1910319.

Koch M, DeKosky ST, Fitzpatrick AL, Furtado JD, Lopez OL, Kuller LH, Mackey RH, Hughes TM, Mukamal KJ, Jensen MK. Apolipoproteins and Alzheimer’s pathophysiology. Alzheimers Dement (Amst). 2018; 10:545-53.

Koch M, Furtado JD, Falk K, Leypoldt F, Mukamal KJ, Jensen MK. Apolipoproteins and their subspecies in human cerebrospinal fluid and plasma. Alzheimers Dement (Amst). 2017; 6:182-7.

Koch M, Freitag-Wolf S, Schlesinger S, Borggrefe J, Hov JR, Jensen MK, Pick J, Markus MRP, Höpfner T, Jacobs G, Siegert S, Artati A, Kastenmüller G, Römisch-Margl W, Adamski J, Illig T, Nothnagel M, Karlsen TH, Schreiber S, Franke A, Krawczak M, Nöthlings U, Lieb W. Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample. Eur J Clin Nutr. 2017; 71:995-1001.

Pubmed library

News and media

BrightFocus Foundation Alzheimer’s Fast Track

Media coverage of our manuscript on alcohol consumption and risk of dementia