Marta Guasch-Ferre

Research Scientist

Department of Nutrition

Research     

Dr. Guasch-Ferré is a Research Scientist at the Department of Nutrition at Harvard T.H. Chan School of Public Health (US) and Instructor in Medicine at Harvard Medical School and Brigham and Women’s Hospital. She holds a PhD in Nutritional Epidemiology. Her research interests include the role of Mediterranean diet on type 2 diabetes and cardiovascular disease. She is currently working on Dietary Interventions, metabolomics, type 2 diabetes and cardiovascular disease in the context of the PREDIMED Study (a randomized clinical trial for primary prevention of cardiovascular disease). She has incorporated high-throughput –omics techniques, metabolomics and genetics, into traditional epidemiological analysis to gain insights into underlying mechanisms that could explain the associations between diet and lifestyle factors in relation to type 2 diabetes and cardiovascular diseases (CVD).Dr. Guasch-Ferré research is also focused on evaluating the effect of olive oil, nuts and other dietary fats on type 2 diabetes and cardiovascular disease in Mediterranean populations (the PREDIMED Study) but also in non-Mediterranean large cohorts (Nurses’ Health Study I and II and Health Professionals Follow-up Study).

During her doctoral training, she evaluated the role of key components of the Mediterranean diet, nuts and olive oil, on metabolic syndrome, cardiovascular risk factors, cardiovascular disease and mortality in individuals at high cardiovascular risk from the PREDIMED Study. Dr. Guasch-Ferré has participated in the design, logistics, dietary interventions, data management, statistical analysis and manuscript preparation of several clinical trials, including the PREDIMED Study (more than 7,000 participants were randomized to three different interventions).

Education

Ph.D., 2014, Rovira i Virgili University, Spain

Master in Human Nutrition and Metabolism., 2011, Barcelona University and Rovira i Virgili University, Spain

Bsc. in Human Nutrition and dietetics., 2009, Rovira i Virgili University, Spain

Selected Awards and Honors 

2016, Travel Award, Postdoctoral Assocition, Harvard TH Chan School of Public Health

2017, Finalist Jeremiah and Rose Stamler Research Award for New Investigators, American Heart Association

2018, Early Career Travel Award, American Heart Association

Selected Publications

Guasch-Ferré M, Liu G, Li Y, Sampson L, Manson JE, Salas-Salvadó J, Martínez-González MA, Stampfer MJ, Willett WC, Sun Q, Hu FB. Olive Oil Consumption and Cardiovascular Risk in U.S. Adults. J Am Coll Cardiol. 2020 Apr 21;75(15):1729-1739. PMID: 32147453; PMCID: PMC7233327.

Guasch-Ferré M, Santos JL, Martínez-González MA, Clish CB, Razquin C, Wang D, et al. Glycolysis/gluconeogenesis- and tricarboxylic acid cycle-related metabolites, Mediterranean diet, and type 2 diabetes. Am J Clin Nutr. 2020 Apr 1;111(4):835-844. PMID: 32060497; PMCID: PMC7138680.

Guasch-Ferré M, Satija A, Blondin SA, Janiszewski M, Emlen E, O’Connor LE, Campbell WW, Hu FB, Willett WC, Stampfer MJ. Meta-Analysis of Randomized Controlled Trials of Red Meat Consumption in Comparison With Various Comparison Diets on Cardiovascular Risk Factors. Circulation. 2019 Apr 9;139(15):1828-1845.  PMID: 30958719.

Guasch-Ferré M, Liu X, Malik VS, Sun Q, Willett WC, Manson JE, Rexrode KM, Li  Y, Hu FB, Bhupathiraju SN. Nut Consumption and Risk of Cardiovascular Disease. J  Am Coll Cardiol. 2017 Nov 14;70(20):2519-2532. doi: 10.1016/j.jacc.2017.09.035. PubMed PMID: 29145952; PubMed Central PMCID: PMC5762129.

Guasch-Ferré M, Hruby A, Toledo E, Clish CB, Martínez-González MA, Salas-Salvadó J, Hu FB. Metabolomics in Prediabetes and Diabetes: A Systematic Review and Meta-analysis. Diabetes Care. 2016 May;39(5):833-46.

Guasch-Ferré M, Zheng Y, Ruiz-Canela M, Hruby A, Martínez-González MA, Clish CB, Corella D, Estruch R, Ros E, Fitó M, et al. Plasma acylcarnitines and risk of cardiovascular disease: effect of Mediterranean diet interventions. Am J  Clin Nutr. 2016 Jun;103(6):1408-16.

Guasch-Ferré M, Bulló M, Martínez-González MÁ, Ros E, Corella D, Estruch R, Fitó M, Arós F, Wärnberg J, Fiol M, et al. Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial. BMC Med. 2013 Jul 16;11:164.