Center for Nanotechnology and Nanotoxicology

Fang Zhang

Short Bio

Dr. Fang Zhang was a Visiting Scholar at Harvard School of Public Health. Dr. Zhang completed Postdoctoral research at Institute of High Energy of Physics, Chinese Academy of Sciences with a specialty of Application of Nuclear Techniques (2003-2005). She earned her BS degree in Hebei Normal University, in China. She completed her MS degree at Sichuan University in Inorganic Chemistry (1997). She received her PhD in Particle Physics and Nuclear Physics (2006) from Institute of High Energy of Physics (2003). She has published numerous papers, holds three projects of NSFC in China.

Research Interests

My recent interest is focused on the bio-effect of airborne particulate matters and nano-materials on human health. The majority of the work is devoted to identifying the role of element composition, chemical speciation and particle size in the toxicology of particles, especially related to cardiovascular or respiratory disease. In addition, much of the work is attempting to understand the pathways of acute respiratory and cardiovascular disease associated with oxidative stress induced by those particles. I also attempt to evaluate the health hazard of motor vehicle exhaust emission in the metropolis.

Selected Publications

  1. XiaoBei Deng, Wei Rui, Fang Zhang*, Wenjun Ding*. PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells. Cell Biol Toxicol. 2013, 29: 143-157.
    1. Xiaobei Deng, Fang Zhang, Wei Rui, Fang Long, Lijuan Wang, Zhaohan Feng, Deliang Chen, Wenjun Ding*. PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells. Toxicology in Vitro. 2013, 27: 1762-1770.
    2. Shuo Yi, Fang Zhang, Fang Qu, Wenjun Ding*. Water-Insoluble Fraction of Airborne Particulate Matter (PM10) Induces Oxidative Stress in Human Lung Epithelial A549 Cells. Environmental Toxicology. 2012, doi: 10.1002/tox.21750.
    3. Han Wei, Dan Wei, Shuo Yi, Wenjun Ding*, Fang Zhang*. Oxidative-stress is induced in human EA.hy926 endothelial cells exposed to fractions of urban fine particles. Human and Experimental Toxicology. 2011, 30(7): 579-590.
    4. Lijuan Wang, Lin Wang, Wenjun Ding* and Fang Zhang*.Acute Toxicity of Ferric Oxide and Zinc Oxide Nanoparticles in Rats. Journal of Nanoscience and Nanotechnology 2010, 10(1): 1-8.