Georgios Pyrgiotakis


Prior Title and Affiliation

Research Scientist
Harvard T.H. Chan School of Public Health
Environmental Health
Center for Nanotechnology and Nanotoxicology

Short Bio

Dr. George Pyrgiotakis was a Research Scientist at the Harvard School of Public Health and acting manager of the Laboratory of Environmental Health NanoSciences (LEHNS). His research interests focused on the investigation of nanoparticle toxicity and how it correlates to nanoparticle properties, such as size, surface morphology, shape, porosity, etc.

Dr. Pyrgiotakis completed Postdoctoral research at the Particle Engineering Research Center at the University of Florida (2006-2010). He earned his BS degree in Physics from the University of Crete, in Greece. He completed his MS degree at the University of Florida in Materials Science and Engineering with a concentration in Electronic Materials. He holds a PhD in Materials Science and Engineering (2006) with a specialty in Ceramic Materials from the University of Florida. He has written numerous publications, book chapters and holds one patent.

Research Interests

Dr. Pyrgiotakis’ main research objective is the investigation of the nano-bio interface and understand the interactions between nanoparticles and cells. Interactions at this level can become determinant in nanotoxicology and nano theragnostics. To facilitate this, over the years, various research endeavors have relied on Raman spectroscopy, Atomic Force Microscope, in-vitro and in-vivo (instilation, inhalation) studies. Dr. Pyrgiotakis’ research interests are expand to other scientific topics including:

  • Colloidal stability and surface chemistry
  • Photocatalysis
  • Aerosol Physics
  • Bacteria inactivation

Center Involvement

  1. Particle to particle and particle to cell interactions in physiologic fluids using Atomic Force Microscopy (AFM).
  2. Safe by design: Demonstrating the efficiency of a safer formulation concept for flame-generated engineered nanomaterials (ENMs)
  3. Acute inhalation study of realistic nano scale CeO2 using the Harvard VENGES toxicological platform
  4. A novel method for bacteria inactivation in air and on surfaces using Engineered Water Nanostructures.

Selected Publications

  1. Gass S, Cohen JM, Pyrgiotakis G, Sotiriou GA, Pratsinis SE, Demokritou P. A safer formulation concept for flame generated nanomaterials. ACS Sus Chem Eng. 2013 Oct;1(7):843-57
  2. Demokritou P, Gass S, Pyrgiotakis G, Cohen JM, Goldsmith W, McKinney W, Frazer D, Ma J, Schwegler-Berry D, Brain JD, Castranova V. An in vivo and in vitro toxicological characterisation of realistic nanoscale CeO2 inhalation exposures. Nanotoxicology. 2013 Dec;7(8):1338-50.
  3. 40. Pyrgiotakis G, McDevitt J, Yamauchi T, Demokritou P. A novel method for bacterial inactivation using electrosprayed water nanostructures. J Nanopart Res. 2012 Aug;14(8).
  4. Cohen JM, DeLoid G, Pyrgiotakis G, Demokritou P. Interactions of engineered nanomaterials in physiological media and the implications for in vitro dosimetry. Nanotoxicology. 2013 Jun;7(4):417-31.
  5. Raman Spectroscopy for Clinical Oncology. M. B. Fenn, P. Xanthopoulos, G. Pyrgiotakis, S. R. Grobmyer, P. M. Pardalos, and L. L. Hench, Advances in Optical Technologies (2012) doi:10.1155/2011/213783