Publications

2021

  1. Moschovis PP, Yonker LM, Shah J, Singh D, Demokritou P, Kinane TB. Aerosol Transmission of SARS-CoV-2 by Children and Adults During the COVID-19 Pandemic. Pediatric Pulmonology. 2021 Feb 21. In press. [link]
  2. Cao X, Khare S, DeLoid GM, Gokulan K, Demokritou P. Co-exposure to boscalid and TiO2 (E171) or SiO2 (E551) downregulates cell junction gene expression in small intestinal epithelium cellular model and increases pesticide translocation. NanoImpact. 100306. [link]

2020

  1. Touloumes GJ, Ardoña HAM, Casalino EK, Zimmerman JF, Chantre CO, Bitounis D, Demokritou P, Parker KK. Mapping 2D- and 3D-distributions of metal/metal oxide nanoparticles within cleared human ex vivo skin tissues. NanoImpact. 2020 Jan 6. 17:100208. doi: 10.1016/j.impact.2020.100208 [link]
  2. Duan Y, Coreas R, Liu Y, Bitounis D, Zhang Z, Parviz D, Strano M, Demokritou P, Zhong W. Prediction of protein corona on nanomaterials by machine learning using novel descriptions. NanoImpact.2020 Jan 16. 17: 100207. doi: 10.1016/j.impact.2020.100207 [link]
  3. Khare S, DeLoid GM, Molina RM, Gokulan K, Couvillion SP, Bloodsworth KJ, Eder EK, Wong AR, Hoyt DW, Bramer LM, Metz TO, Thrall BD, Brain JD, Demokritou P. Effects of ingested nanocellulose on intestinal microbiota and homeostasis in Wistar Han rats. NanoImpact. 2020 Feb 28. 18:100216. [link]
  4. O’Connor BB, Grevesse T, Zimmerman JF, Ardoña HAM, Jimenez JA, Bitounis D, Demokritou P, Parker KK. Human brain microvascular endothelial cell pairs model tissue-level blood-brain barrier function. Integrative Biology. 2020 March 20. 12(3):64-79. doi: 10.1093/intbio/zyaa005 [link]
  5. Bitounis D, Parviz D, Cao X, Amadei CA, Vecitis CD, Sunderland E, Thrall B, Fang M, Strano MS, Demokritou P. Synthesis and physicochemical transformations of size-sorted graphene oxide during simulated digestion and its toxicological assessment against an in vitro model of the human intestinal epithelium. Small. 2020 Mar 20. 1907640. doi: 10.1002/smll.201907640 [link]
  6. Parviz D, Bitounis D, Demokritou P, Strano M. Engineering two-dimensional nanomaterials to enable structure-activity relationship studies in nanosafety research. NanoImpact. 2020 April 18. 100226. [link]
  7. Wu Z, Shi P, Lim HK, Ma Y, Setyawati MI, Bitounis D, Demokritou P, Ng KW, Tay CY. Inflammation increases susceptibility of human alveolar epithelial cells to pneumonic nanotoxicity. Small, 16(21), 2000963. [link]
  8. Yang Q, Keerthisinghe TP, Rou T, Tan J, Cao X, Setyawati MI, DeLoid G, Ng KW, Loo J, Demokritou P,   Fang M. A high-throughput method to characterize the gut bacteria growth upon engineered nanomaterial treatment. Environmental Science: Nano. 2020 Aug 20. 7:3155-66. [link]
  9. Cao X, Zhang T, DeLoid GM, Gaffrey MJ, Weitz KK, Thrall BD, Qian W, Demokritou P. Cytotoxicity and cellular proteome impact of cellulose nanocrystals using simulated digestion and an in vitro small intestinal epithelium cellular model. 2020 October 20. 100269. [link]
  10. Coreas R, Cao X, DeLoid GM, Demokritou P, Zhong W. Lipid and protein corona of food-grade TiO2 nanoparticles in simulated gastrointestinal digestion. Nanoimpact. 2020 Nov 3. 100272. [link]
  11. Gonçalves J, Pipek LZ, Donaghey TC, DeLoid GM, Demokritou P, Brain JD, Molina RM. Effects of ingested nanomaterials on tissue distribution of co-ingested zinc and iron in normal and zinc-deficient mice. NanoImpact. 2020 Dec 5. 21: 100279. [link]

2019

  1. Salari, M., Bitounis, D., Bhattacharya, K., Pyrgiotakis, G., Zhang, Z., Purington, E., Gramlich, W., Grondin, Y., Rogers, R., Bousfield, D., Demokritou, P., 2019. Development & characterization of fluorescently tagged nanocellulose for nanotoxicological studies. Environ. Sci.: Nano. https://doi.org/10.1039/C8EN01381K
  2. Zhang Z, Zhang R, Xiao H, Bhattacharya K, Bitounis D, Demokritou P, et al. Development of a standardized food model for studying the impact of food matrix effects on the gastrointestinal fate and toxicity of ingested nanomaterials. NanoImpact. Elsevier; 2019;13: 13–25. doi:10.1016/J.IMPACT.2018.11.002 [link]
  3. Zimmerman JF, Ardoña HAM, Pyrgiotakis G, Dong J, Moudgil B, Demokritou P, Parker KK. Scatter Enhanced Phase Contrast Microscopy for Discriminating Mechanisms of Active Nanoparticle Transport in Living Cells. Nano Letters. 2019 Jan;19(2):793–804. doi:10.1021/acs.nanolett.8b03903 [link]
  4. Purington, E., Bousfield, D., Gramlich, W.M., 2019. Fluorescent dye adsorption in aqueous suspension to produce tagged cellulose nanofibers for visualization on paper. Cellulose. https://doi.org/10.1007/s10570-019-02439-4
  5. Bitounis D, Pyrgiotakis G, Bousfield D, Demokritou P. Dispersion preparation, characterization, and dosimetric analysis of cellulose nano-fibrils and nano-crystals: Implications for cellular toxicological studies. NanoImpact. 2019 May 31. 15:100171. doi: 10.1016/j.impact.2019.100171. [link]
  6. Deloid G, Cao X, Molina R, Silva DI, Bhattacharya K, Ng KW, Loo SCJ, Brain J, Demokritou P. Toxicological effects of ingested nanocellulose in in vitro interstinal epithelium and in vivo rat models. Environmental Science:Nano. 2019 June 14; 6(7):2105-2115. doi: 10.1039/C9EN00184K [link]
  7. Dong J, Carpinone PL, Pyrgiotakis G, Demokritou P, Moudgil BM. Synthesis of Precision Gold Nanoparticles Using Turkevich Method. KONA Powder and Particle Journal. 2020 January 10. In press. doi: 10.14356/kona.2020011 [link]
  8. Cao X, DeLoid G, Bitounis D, De La Torre-Roche R, White JC, Zhang Z, Guan Ho C, Ng KW, Eitzer BD, Demokritou P. Co-exposure to the food additives SiO2 (E551) or TiO2 (E171) and the pesticide boscalid increases cytotoxicity and bioavailability of the pesticide in a tri-culture small intestinal epithelium model: potential health implications. Environmental Science: Nano. 2019 Aug 8; 6(9):2786-2800. doi: 10.1039/C9EN00676A [link]
  9. Rubio L, Pyrgiotakis G, Beltran-Huarac J, Zhang Y, Gaurav J, Deloid G, Spyrogianni A, Sarosiek KA, Bello D, Demokritou P. Safer-by-design flame-sprayed silicon dioxide nanoparticles: the role of silanol content on ROS generation, surface activity and cytotoxicity. Particle & Fibre Toxicology. 2019 October 29; 16(40). Doi: 10.1186/s12989-019-0325-1 [link]
  10. Kim S, Gates B, Leonard BC, Gragg M, Pinkerton KE, Van Winkle L, Murphy CH, Pyrgiotakis G, Zhang Z, Demokritou P, Thomasy SM. Engineered metal oxide nanomaterials inhibit corneal epithelial wound healing in vitro and in vivo. NanoImpact. 2019 Dec 6. 17:100198. doi: 10.1016/j.impact.2019.100198 [link]
  11. Cao X, Zhang T, DeLoid GM, Gaffrey MJ, Weitz KK, Thrall BD, Qian W, Demokritou P. Evaluation of the cytotoxic and cellular proteome impacts of food-grade TiO2 (E171) using simulated gastrointestinal digestions and a tri-culture small intestinal epithelial model. NanoImpact. 2019 Dec 6. 17:100202. doi: 10.1016/j.impact.2019.100202 [link]

2018

  1. Ahn S, Ardoña HAM, Lind JU, Eweje F, Kim SL, Gonzalez GM, et al. Mussel-inspired 3D fiber scaffolds for heart-on-a-chip toxicity studies of engineered nanomaterials. Anal Bioanal Chem. 2018;410: 6141–6154. doi:10.1007/s00216-018-1106-7 [link]
  2. Beltran-Huarac J, Zhang Z, Pyrgiotakis G, DeLoid G, Vaze N, Demokritou P. Development of reference metal and metal oxide engineered nanomaterials for nanotoxicology research using high throughput and precision flame spray synthesis approaches. NanoImpact. 2018;10: 26–37. doi:10.1016/j.impact.2017.11.007 [link]
  3. Cohen JM, Beltran-Huarac J, Pyrgiotakis G, Demokritou P. Effective delivery of sonication energy to fast settling and agglomerating nanomaterial suspensions for cellular studies: Implications for stability, particle kinetics, dosimetry and toxicity. NanoImpact. 2018; doi:10.1016/j.impact.2017.12.002 [link]
  4. Deloid GM, Sohal IS, Lorente LR, Molina RM, Pyrgiotakis G, Stevanovic A, et al. Reducing Intestinal Digestion and Absorption of Fat Using a Nature-Derived Biopolymer: Interference of Triglyceride Hydrolysis by Nanocellulose. ACS Nano. American Chemical Society; 2018;12: 6469–6479. doi:10.1021/acsnano.8b03074 [link]
  5. Lee JY, Wang H, Pyrgiotakis G, DeLoid GM, Zhang Z, Beltran-Huarac J, et al. Analysis of lipid adsorption on nanoparticles by nanoflow liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2018; doi:10.1007/s00216-018-1145-0 [link]
  6. Parviz D, Strano M. Endotoxin-Free Preparation of Graphene Oxide and Graphene-Based Materials for Biological Applications. Curr Protoc Chem Biol. 2018;10: e51. doi:10.1002/cpch.51 [link]
  7. Pyrgiotakis G, Luu W, Zhang Z, Vaze N, DeLoid G, Rubio L, et al. Development of high throughput, high precision synthesis platforms and characterization methodologies for toxicological studies of nanocellulose. Cellulose. Springer Netherlands; 2018;25: 2303–2319. doi:10.1007/s10570-018-1718-2 [link]

2017

  1. DeLoid GM, Wang Y, Kapronezai K, Lorente LR, Zhang R, Pyrgiotakis G, Konduru NV, Ericsson M, White JC, De La Torre-Roche R, Xiao H, McClements DJ, Demokritou P. An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials. Part Fibre Toxicol. 2017 Oct; 14(1);40. [link]
  2. Stueckle TA, Davidson DC, Derk R, Kornberg T, Schwegler-Berry D, Pirela SV, Deloid G, Demokritou P, Luanpitpong S, Rojanasakul Y, Wang L. Evaluation of tumorigenic potential of CeO2 and Fe2O3 engineered nanoparticles by a human cell in vitro screening model. NanoImpact. 2017 Apr;6:39-54. [link]
  3. Eleftheriadou M, Pyrgiotakis G, Demokritou P. Nanotechnology to the rescue: using nano-enabled approaches in microbiological food safety and quality. Curr Opin Biotechnol. 2017 Apr;44:87–93. [link]
  4. DeLoid GM, Cohen JM, Pyrgiotakis G, Demokritou P. Preparation, characterization, and in vitro dosimetry of dispersed, engineered nanomaterials. Nat Protoc. 2017 Jan;12(2):355–71. [link]

2016

  1. McClements DJ, DeLoid G, Pyrgiotakis G, Shatkin JA, Xiao H, Demokritou P. The role of the food matrix and gastrointestinal tract in the assessment of biological properties of ingested engineered nanomaterials (iENMs): State of the science and knowledge gaps. NanoImpact. 2016 Jul;3–4(1):47–57. [link]