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Personalized medicine still a long way away, says Cutter Lecture speaker
May 31, 2012 -- Lung cancer makes up only 15 percent of cancer diagnoses, but it is the leading cause of cancer deaths. To help doctors detect the disease in its early, most treatable stages, epidemiologists like Margaret…
Modeling gene-gene and gene-environment interaction may not substantially improve disease risk prediction
For immediate release: Thursday, May 24, 2012 Boston, MA —Harvard School of Public Health (HSPH) researchers have found that detailed knowledge about your genetic makeup—the interplay between genetic variants and other genetic variants, or between genetic variants and…
Whole-genome sequencing of 2011 E. Coli outbreaks in Europe provides new insight into origins, spread of disease
For immediate release: Monday, February 6, 2012 Boston, MA — Using whole-genome sequencing, a team led by researchers from Harvard School of Public Health (HSPH) and the Broad Institute has traced the path of the E. coli outbreak…
Searching for answers to causes of childhood depression
February 1, 2012 Over the past decade, scientists have produced a flurry of studies exploring the role of genetic (nature) and environmental factors (nurture) in youth depression, but there has been little consensus on how depression is jointly impacted by…
New standard helps bioscience researchers overcome data-sharing obstacles
Collaborators from 30 scientific organizations worldwide, led by researchers at the University of Oxford and the Harvard School of Public Health (HSPH), have agreed on a common standard designed to enable life scientists from widely disparate fields to…
Conference addresses quantitative challenges of using complex genomics data in medical research
December 13, 2011 With the completion of the 13-year Human Genome Project in 2003, many scientists have been hopeful that the wealth of new genetic information would help predict disease risk for individuals, help doctors ascertain which drugs…
Researchers shed light on what triggers tumors in lung cancer
October 12, 2011 -- For decades cigarette smoking has been considered a risk factor for lung cancer, but exactly how tobacco use causes tumors to grow in the lungs is not fully understood. A new study led by…
HSPH study suggests natural selection at work in certain disease-related genes
September 29, 2011 A new study led by Harvard School of Public Health (HSPH) researchers implies that, among three closely related African-ancestry populations, natural selection is at work in genes related to malaria and bladder and gastric cancers.…
Unlocking the secrets of drug resistance in malaria parasites
[ Fall 2011 ] New Gene Search Tool Opens “Endless Possibilities” During a half-century of global efforts to conquer malaria, scientists have developed a series of antimalarial drugs, only to see them defanged, one by one, by the…
Study finds coffee craving may be in the genes
A new study co-authored by HSPH researchers has identified a genetic propensity for caffeine consumption. The researchers discovered two genes that drive people to consume more or less caffeine depending on which variation of the genes they possess.…