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Analyzing entire malaria parasite genome provides clues on malaria drug resistance
August 2, 2012 -- Using a more thorough type of analysis than has been used before to examine the genetic makeup of the malaria parasite, researchers from Harvard School of Public Health (HSPH), Harvard University, and the Broad…
HSPH researchers uncover how a key inflammatory pathway is regulated
July 2, 2012 -- Findings could help identify new therapeutic targets for inflammatory diseases A team of scientists led by Harvard School of Public Health (HSPH) researchers has discovered how a protein complex known as the NLRP3 inflammasome, part…
Human microbiome project outlines powerful new methods for cataloging and analyzing microbes that play role in health and disease
For immediate release: Wednesday, June 13, 2012 Boston, MA — New studies led by Harvard School of Public Health (HSPH) researchers have helped identify and analyze the vast human “microbiome”—the more than five million microbial genes that exist…
Personalized medicine still a long way away, says Cutter Lecture speaker
May 31, 2012 -- Lung cancer makes up only 15 percent of cancer diagnoses, but it is the leading cause of cancer deaths. To help doctors detect the disease in its early, most treatable stages, epidemiologists like Margaret…
Modeling gene-gene and gene-environment interaction may not substantially improve disease risk prediction
For immediate release: Thursday, May 24, 2012 Boston, MA —Harvard School of Public Health (HSPH) researchers have found that detailed knowledge about your genetic makeup—the interplay between genetic variants and other genetic variants, or between genetic variants and…
Whole-genome sequencing of 2011 E. Coli outbreaks in Europe provides new insight into origins, spread of disease
For immediate release: Monday, February 6, 2012 Boston, MA — Using whole-genome sequencing, a team led by researchers from Harvard School of Public Health (HSPH) and the Broad Institute has traced the path of the E. coli outbreak…
Searching for answers to causes of childhood depression
February 1, 2012 Over the past decade, scientists have produced a flurry of studies exploring the role of genetic (nature) and environmental factors (nurture) in youth depression, but there has been little consensus on how depression is jointly impacted by…
New standard helps bioscience researchers overcome data-sharing obstacles
Collaborators from 30 scientific organizations worldwide, led by researchers at the University of Oxford and the Harvard School of Public Health (HSPH), have agreed on a common standard designed to enable life scientists from widely disparate fields to…
Conference addresses quantitative challenges of using complex genomics data in medical research
December 13, 2011 With the completion of the 13-year Human Genome Project in 2003, many scientists have been hopeful that the wealth of new genetic information would help predict disease risk for individuals, help doctors ascertain which drugs…
Researchers shed light on what triggers tumors in lung cancer
October 12, 2011 -- For decades cigarette smoking has been considered a risk factor for lung cancer, but exactly how tobacco use causes tumors to grow in the lungs is not fully understood. A new study led by…