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Examining epigenetics’ influence on obesity, cancer
In recent decades, researchers have been examining the role of epigenetics—the study of modifications in DNA that do not alter the DNA sequence itself but can lead to lifelong changes in gene activity—in the development of dozens of…
Should your next checkup include a genetic test?
With the recent proliferation of genetic testing services, routine checkups could soon include having one’s genome screened. A recent opinion piece in the Annals of Internal Medicine argued in favor of the idea, noting that it’s possible that…
Breakthrough brings targeted drug delivery within ARMM's reach
Scientists at Harvard T.H. Chan School of Public Health demonstrated a new vesicle-based system for delivering molecular cargo into cells—a discovery that may significantly improve targeted drug delivery.
Gene linked with lower asthma risk identified
Researchers from Harvard T.H. Chan School of Public Health have identified a gene associated with lower asthma risk and its role in the disease’s progression—findings that open a new potential pathway for treatment.
Targeting tumor metabolic vulnerabilities
December 8, 2017 – A research team at Harvard T.H. Chan School of Public Health has identified a key metabolic vulnerability in some types of tumor cells and discovered a way to exploit it by harnessing well-known immunosuppressant…
Need an automatic gamma wizard? New instrumentation network enables sharing of lab equipment
The School’s new Shared Instrumentation Network is a website listing equipment that is available for community members to use.
Manipulating mitochondrial networks could promote healthy aging
Manipulating mitochondrial networks inside cells—either by dietary restriction or by genetic manipulation that mimics it—may increase lifespan and promote health.
Dozens of new genetic regions linked to breast cancer
Two studies represent the largest-ever examination of the inherited genetic contribution to the risk of getting breast cancer For immediate release: October 23, 2017 Boston, MA – Two large genome-wide association studies of thousands of women have identified…
Targeting ‘lipid chaperones’ may hold promise for lifelong preservation of metabolic health
Researchers have found that, in a mouse model, it may be possible to achieve lifelong metabolic health. The Harvard T.H. Chan School of Public Health scientists found that mice that lack fatty acid-binding proteins (FABPs) exhibit substantial protection…
Thousands of new microbial communities identified in human body
Study sheds light on differences unique to individuals’ microbes For immediate release: September 20, 2017 Boston, MA – A new study of the human microbiome—the trillions of microbial organisms that live on and within our bodies—has analyzed thousands…