Vaping and Lung Inflammation and Injury.

Author(s): Park JA, Crotty Alexander LE, Christiani DCJournal: Annu Rev PhysiolPMID: 34724436 February 2022
The use of electronic (e)-cigarettes was initially considered a beneficial solution to conventional cigarette smoking cessation. However, paradoxically, e-cigarette use…

Integrative omics provide biological and clinical insights into acute respiratory distress syndrome.

Author(s): Du M, Garcia JGN, Christie JD, Xin J, Cai G, Meyer NJ, Zhu Z, Yuan Q, Zhang Z, Su L, Shen S, Dong X, Li H, Hutchinson JN, Tejera P, Lin X, Wang M, Chen F, Christiani DCJournal: Intensive Care MedPMID: 34032881 February 2022
Acute respiratory distress syndrome (ARDS) is accompanied by a dysfunctional immune-inflammatory response following lung injury, including during coronavirus disease 2019…

Bayesian kernel machine regression-causal mediation analysis.

Author(s): Devick KL, Bobb JF, Mazumdar M, Claus Henn B, Bellinger DC, Christiani DC, Wright RO, Williams PL, Coull BA, Valeri LJournal: Stat MedPMID: 34993981 January 2022
Greater understanding of the pathways through which an environmental mixture operates is important to design effective interventions. We present new…