As a faculty member with joint appointments in both Biostatistics and Epidemiology, I have focused my research over the last 25 years on environmental epidemiology studies and on HIV-related clinical trials and observational studies, with a common focus on reproductive outcomes and child development. A major focus of my HIV-related research is the safety evaluation of reproductive health outcomes in infants exposed in utero to antiretroviral agents, such as congenital anomalies, preterm birth, and low birth weight, in addition to longer term outcomes such as cardiotoxicity, neurodevelopment and behavioral functioning. My other active area of research is reproductive epidemiology in relation to environmental, nutritional, and other prenatal exposures. I have particular interest in birth and reproductive outcomes associated with prenatal exposures to endocrine disrupting chemicals (EDCs), such as phthalates, dioxins, pesticides, and heavy metals such as lead.

My statistical interests are broad and include mediation analysis, survival outcomes, clustered data, and statistical methods for evaluation of mixtures. I mentor many doctoral and masters students in biostatistics and epidemiology, and also mentor other research staff through my involvement in many collaborative studies.

Learn more about my research interests.

Courses Taught

Effective Grant and Research Proposal Writing for Biostatistics (BIST254), HSPH | 2017-present
Applied Survival Analysis (BIO223), HSPH | 2012-2015
Basics of Statistical Inference (BIO222), HSPH | 2007-2009
Advanced Multivariate Analysis (BIO245), HSPH | 2003-2006
Applied Survival Analysis (BIO223), HSPH | 1998-2000
Applied Survival Analysis (3-week intensive course), University of Athens | 1999
Statistical Methods for Bioassay Studies (BIO266), HSPH | 1996, 1998
(co-taught with Drs. Louise Ryan & Paul Catalano)
Design & Analysis of Animal Bioassay Experiments (short course), University of Newcastle | 1996
Discrete Data Analysis (BIO221), HSPH | 1994-1995
Statistical Methods for Health Policy and Management (BIH204), HSPH | 1991-1993
Advanced Quantitative Methods for Health Policy, University of North Carolina, Chapel Hill | 1988

Awards, Grants & Honors

James Grizzle Distinguished Alumnus Award, UNC-Chapel Hill | 1998
First Independent Research Support and Transition (FIRST) Award | 1996-2001
Harvard-Schering Plough Fellowship | 1994-1995
NSF Young Investigators Award | 1994
Bok Grant for Innovations in Teaching, HSPH | 1991


University of North Carolina at Chapel Hill – PhD, Biostatistics | 1990
University of North Carolina at Chapel Hill – MS, Biostatistics | 1984
University of North Carolina at Chapel Hill – BSPH | 1983