Poster Session

Session I: Identifying causal genes and pathways

Presenter	Poster Number, Title, & Authors
Lilit Antonyan	1. Genome-Wide Association Study on Obsessive Compulsive Traits Using a Quantitative Symptom Measure Lilit Antonyan, S-M Shaheen, Gregory Hanna, David Rosenberg, Paul Arnold
Diana Avalos	2. Genetic variation in cis regulatory domains and trans regulatory hubs of immunity Diana Avalos, Guillaume Rey, Anna Ramisch, Olivier Delaneau, Emmanouil T Dermitzakis
Jenna Ballard	3. Characteristics beyond correlation in multi-trait effect-size distributions Jenna L Ballard and Luke J O’Connor
Arjun Battacharya	4. MOSTWAS: Multi-omic strategies for transcriptome-wide prediction and association studies Arjun Bhattacharya, Yun Li, Rebecca C. Fry, Hudson P. Santos Jr, Michael I. Love
Carles Boix	5. Integrative analysis of 10,000 epigenomic maps across 800 samples for regulatory genomics and disease dissection Carles Boix, Ben James, Yongjin Park, Wouter Meuleman, Manolis Kellis
Brielin Brown	6. Phenome-scale directed network discovery with bi-directional mediated Mendelian randomization Brielin C Brown, David A Knowles
Terence Capellini	7. Separate regulatory variants on a common risk haplotype at GDF5-UQCC1 underlie knee osteoarthristis risk and developmental dysplasia of the hip in vivo Terence D. Capellini, Pushpanathan Muthuirulan, Zun Liu, Ata M. Kiapour, Jiaxue Cao, Jakob Sieker, Siddharth Yarlagadda, David E. Maridas, Vicki Rosen, Mariel Young
Yonatan Cooper	8. Identification of common regulatory variants underlying tauopathies using massively parallel reporter assays Yonatan Cooper, Giovanni Coppola, Dan Geschwind
Nicholas Darci-Maher	9. Cross-tissue omics analysis between adipose tissue and liver identifies novel serum biomarker candidates for non-alcoholic fatty liver disease Nicholas Darci-Maher, Marcus Alvarez, David Z Pan, Zong Miao, Dorota Kaminska, Jussi Pihlajamäki, Päivi Pajukanta
Aimee Deaton	10. Gene-level analysis of loss of function variants in 246,730 whole exome sequences reveals an association of GIGYF1 with diabetes Aimee M. Deaton, Margaret M. Parker, Lucas D. Ward, Alexander O. Flynn-Carroll, Lucas BonDurant, Gregory Hinkle, Paul Nioi
Kushal Dey	11. Disease-critical cell types and cellular processes across the human body Kushal K Dey, Karthik A Jagadeesh, Daniel Montoro, Jesse Engreitz, Ramnik Xavier, Alkes Price, Aviv Regev
Mulong Du	12. Evidence from large-scale population supporting the causal cascade of CYP26A activity, smoking dose, and lung cancer risk Mulong Du, Qianyu Yuan, Zhengdong Zhang, Guoshuai Cai, Qingyi Wei, Philip Lazarus, David C. Christiani
Diptavo Dutta	13. Aggregative trans-eQTL associations detect trait-specific target gene sets Diptavo Dutta, Yuan He, Ashis Saha, Marios Arvanitis, Alexis Battle, Nilanjan Chatterjee
Esther Herrera-Luis	14. Admixture mapping analysis of asthma exacerbations in African Americans Esther Herrera-Luis, Fabian Lorenzo-Diaz, Angel C. Y. Mak, Esteban G. Burchard, Maria Pino-Yanes
Ruth Johnson	15. Fine-scale estimates of regional polygenicity provide insights into the genetic architecture of complex traits Ruth Johnson, Kathryn Burch, Kangcheng Hou, Bogdan Pasaniuc, Sriram Sankararaman
Pavel Kuksa	16. SparkINFERNO: next-generation high-throughput pipeline for inferring molecular mechanisms of non-coding genetic associations Pavel P. Kuksa, Chien-Yueh Lee, Prabhakaran Gangadharan, Otto Valladares, Yuk Yee Leung, Li-San Wang
Seung Hyuk (Tony) Lee	17. Abdominal obesity GWAS variants regulate adipose cell-type signature genes Seung Hyuk (Tony) Lee, Marcus Alvarez, David Z. Pan, Uma Thanigai Arasu, Tiit Örd, Dorota Kaminska, Sini Heinonen, Kirsi H Pietiläinen, Minna U Kaikkonen, Jussi Pihlajamäki, Päivi Pajukanta
Jimmy Tsz Hang Lee	18. Fast searches of single cell datasets by variant and trait Jimmy Tsz Hang Lee, Nikolaos Patikas, Vladimir Yu Kiselev, Martin Hemberg
Jiajin Li	19. Rare variants regulate expression of nearby individual genes in multiple tissues Jiajin Li, Nahyun Kong, Buhm Han, Jae Hoon Sul
Xihao Li	20. Scalable rare variant meta-analysis of whole genome sequencing studies using summary statistics and functional annotations Xihao Li, Zilin Li, Corbin Quick, Hufeng Zhou, Sheila M. Gaynor, Han Chen, Jerome I. Rotter, Cristen J. Willer, Pradeep Natarajan, Gina M. Peloso, and Xihong Lin, on behalf of the TOPMed Lipids Working Group, BioData Catalyst Consortium
Zilin Li	21. A Framework for Detecting Noncoding Associations in Large-Scale Whole Genome Sequencing Studies Zilin Li, Xihao Li, Hufeng Zhou, Sheila M. Gaynor, Margaret Sunitha, Akhil Pampana, Jerome I. Rotter, Cristen J. Willer, Gina M. Peloso, Pradeep Natarajan and Xihong Lin, on behalf of the TOPMed Lipids Working Group
Chen Mo	22. Genetic Fine-mapping via Learning Graph Structures of Linkage Disequilibrium Patterns Chen Mo, Zhenyao Ye, Tianzhou Ma, Shuo Chen
Achal Patel	23. Differential germline associations with risk of recurrence scores in White and Black breast cancer patients A. Patel, A. Bhattacharya, M.I. Love, M.A. Troester
Wouter Peyrot	24. Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS W.J. Peyrot, A.L. Price
Jialin Qu	25. Gene set analysis with graph embedded kernel association test Jialin Qu and Yuehua Cui
Brody Receveur	26. Computationally efficient, exact, multimarker omnibus tests by leveraging individual marker summary statistics from large biobanks Angela Zigarelli, Hanna Venera, Brody Receveur, Jack Wolf, Jason Westra, and Nathan Tintle
Alexandria Szalanczy	27. Verification of Keratinocyte-Associated Protein 3 as a Novel Gene for Adiposity Alexandria M Szalanczy, Osborne Seshie, Emily Goff, Michael Grzybowski, Aron M Geurts, & Leah C Solberg Woods
Ming-Ju Tsai	28. Identifying critical downstream gene targets associated with osteoporosis via gene regulatory landscapes Ming-Ju Tsai, Sjur Reppe, Tadatoshi Sato, Richard Gill, Wein, Marc N, Kaare Gautvik, Yi-Hsiang Hsu
Yi Zhang	29. A Breast Cancer-Associated Genetic Variant Modulates Immune Cells in the Tumor Microenvironment Yi Zhang, Mohith Manjunath, Jialu Yan, Brittany A. Baur, Shilu Zhang, Sushmita Roy, Jun S. Song

Presenter

Poster Number, Title, & Authors

Lilit Antonyan

1. Genome-Wide Association Study on Obsessive Compulsive Traits Using a Quantitative Symptom Measure

Lilit Antonyan, S-M Shaheen, Gregory Hanna, David Rosenberg, Paul Arnold

Diana Avalos

2. Genetic variation in cis regulatory domains and trans regulatory hubs of immunity

Diana Avalos*, Guillaume Rey*, Anna Ramisch, Olivier Delaneau, Emmanouil T Dermitzakis

Jenna Ballard

3. Characteristics beyond correlation in multi-trait effect-size distributions

Jenna L Ballard and Luke J O’Connor

Arjun Battacharya

4. MOSTWAS: Multi-omic strategies for transcriptome-wide prediction and association studies

Arjun Bhattacharya, Yun Li, Rebecca C. Fry, Hudson P. Santos Jr, Michael I. Love

Carles Boix

5. Integrative analysis of 10,000 epigenomic maps across 800 samples for regulatory genomics and disease dissection

Carles Boix, Ben James, Yongjin Park, Wouter Meuleman, Manolis Kellis

Brielin Brown

6. Phenome-scale directed network discovery with bi-directional mediated Mendelian randomization

Brielin C Brown, David A Knowles

Terence Capellini

7. Separate regulatory variants on a common risk haplotype at GDF5-UQCC1 underlie knee osteoarthristis risk and developmental dysplasia of the hip in vivo

Terence D. Capellini, Pushpanathan Muthuirulan, Zun Liu, Ata M. Kiapour, Jiaxue Cao, Jakob Sieker, Siddharth Yarlagadda, David E. Maridas, Vicki Rosen, Mariel Young

Yonatan Cooper

8. Identification of common regulatory variants underlying tauopathies using massively parallel reporter assays

Yonatan Cooper, Giovanni Coppola, Dan Geschwind

Nicholas Darci-Maher

9. Cross-tissue omics analysis between adipose tissue and liver identifies novel serum biomarker candidates for non-alcoholic fatty liver disease

Nicholas Darci-Maher, Marcus Alvarez, David Z Pan, Zong Miao, Dorota Kaminska, Jussi Pihlajamäki, Päivi Pajukanta

Aimee Deaton

10. Gene-level analysis of loss of function variants in 246,730 whole exome sequences reveals an association of GIGYF1 with diabetes

Aimee M. Deaton, Margaret M. Parker, Lucas D. Ward, Alexander O. Flynn-Carroll, Lucas BonDurant, Gregory Hinkle, Paul Nioi

Kushal Dey

11. Disease-critical cell types and cellular processes across the human body

Kushal K Dey, Karthik A Jagadeesh, Daniel Montoro, Jesse Engreitz, Ramnik Xavier, Alkes Price, Aviv Regev

Mulong Du

12. Evidence from large-scale population supporting the causal cascade of CYP26A activity, smoking dose, and lung cancer risk

Mulong Du, Qianyu Yuan, Zhengdong Zhang, Guoshuai Cai, Qingyi Wei, Philip Lazarus, David C. Christiani

Diptavo Dutta

13. Aggregative trans-eQTL associations detect trait-specific target gene sets

Diptavo Dutta, Yuan He, Ashis Saha, Marios Arvanitis, Alexis Battle, Nilanjan Chatterjee

Esther Herrera-Luis

14. Admixture mapping analysis of asthma exacerbations in African Americans

Esther Herrera-Luis, Fabian Lorenzo-Diaz, Angel C. Y. Mak, Esteban G. Burchard, Maria Pino-Yanes

Ruth Johnson

15. Fine-scale estimates of regional polygenicity provide insights into the genetic architecture of complex traits

Ruth Johnson, Kathryn Burch, Kangcheng Hou, Bogdan Pasaniuc*, Sriram Sankararaman*

Pavel Kuksa

16. SparkINFERNO: next-generation high-throughput pipeline for inferring molecular mechanisms of non-coding genetic associations

Pavel P. Kuksa, Chien-Yueh Lee, Prabhakaran Gangadharan, Otto Valladares, Yuk Yee Leung, Li-San Wang

Seung Hyuk (Tony) Lee

17. Abdominal obesity GWAS variants regulate adipose cell-type signature genes

Seung Hyuk (Tony) Lee, Marcus Alvarez, David Z. Pan, Uma Thanigai Arasu, Tiit Örd, Dorota Kaminska, Sini Heinonen, Kirsi H Pietiläinen, Minna U Kaikkonen, Jussi Pihlajamäki, Päivi Pajukanta

Jimmy Tsz Hang Lee

18. Fast searches of single cell datasets by variant and trait

Jimmy Tsz Hang Lee, Nikolaos Patikas, Vladimir Yu Kiselev, Martin Hemberg

Jiajin Li

19. Rare variants regulate expression of nearby individual genes in multiple tissues

Jiajin Li, Nahyun Kong, Buhm Han, Jae Hoon Sul

Xihao Li

20. Scalable rare variant meta-analysis of whole genome sequencing studies using summary statistics and functional annotations

Xihao Li, Zilin Li, Corbin Quick, Hufeng Zhou, Sheila M. Gaynor, Han Chen, Jerome I. Rotter, Cristen J. Willer, Pradeep Natarajan, Gina M. Peloso, and Xihong Lin, on behalf of the TOPMed Lipids Working Group, BioData Catalyst Consortium

Zilin Li

21. A Framework for Detecting Noncoding Associations in Large-Scale Whole Genome Sequencing Studies

Zilin Li, Xihao Li, Hufeng Zhou, Sheila M. Gaynor, Margaret Sunitha, Akhil Pampana, Jerome I. Rotter, Cristen J. Willer, Gina M. Peloso, Pradeep Natarajan and Xihong Lin, on behalf of the TOPMed Lipids Working Group

Chen Mo

22. Genetic Fine-mapping via Learning Graph Structures of Linkage Disequilibrium Patterns

Chen Mo, Zhenyao Ye, Tianzhou Ma, Shuo Chen

Achal Patel

23. Differential germline associations with risk of recurrence scores in White and Black breast cancer patients

A. Patel, A. Bhattacharya, M.I. Love, M.A. Troester

Wouter Peyrot

24. Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS

W.J. Peyrot, A.L. Price

Jialin Qu

25. Gene set analysis with graph embedded kernel association test

Jialin Qu and Yuehua Cui

Brody Receveur

26. Computationally efficient, exact, multimarker omnibus tests by leveraging individual marker summary statistics from large biobanks

Angela Zigarelli, Hanna Venera, Brody Receveur, Jack Wolf, Jason Westra, and Nathan Tintle

Alexandria Szalanczy

27. Verification of Keratinocyte-Associated Protein 3 as a Novel Gene for Adiposity

Alexandria M Szalanczy, Osborne Seshie, Emily Goff, Michael Grzybowski, Aron M Geurts, & Leah C Solberg Woods

Ming-Ju Tsai

28. Identifying critical downstream gene targets associated with osteoporosis via gene regulatory landscapes

Ming-Ju Tsai, Sjur Reppe, Tadatoshi Sato, Richard Gill, Wein, Marc N, Kaare Gautvik, Yi-Hsiang Hsu

Yi Zhang

29. A Breast Cancer-Associated Genetic Variant Modulates Immune Cells in the Tumor Microenvironment

Yi Zhang, Mohith Manjunath, Jialu Yan, Brittany A. Baur, Shilu Zhang, Sushmita Roy, Jun S. Song

Session II: From causal genes and pathways to drug discovery and pharmacogenetics

Presenter	Poster Number, Title, & Authors
Rupam Bhattacharyya	30. TransPRECISE: Proteomics-based Network Modeling of the Pan-cancer Patient and Cell Line Interactome Rupam Bhattacharyya, University of Michigan; Min Jin Ha, The University of Texas MD Anderson Cancer Center; Qingzhi Liu, University of Michigan; Rehan Akbani, The University of Texas MD Anderson Cancer Center; Han Liang, The University of Texas MD Anderson Cancer Center; Veerabhadran Baladandayuthapani, University of Michigan.
Beverly Dosso	31. ELOVL SNPs impact response to PUFA-rich diets and patient outcomes in secondary analysis of OMEGA trial Beverly Dosso, Susan Sergeant, D. Clark Files, Timothy D. Howard, Carl D. Langefeld, Floyd H. Chilton, and Elaheh Rahbar
Chachrit Khunsriraksakul	32. PUMICE- Prediction Using Models Informed by Chromatin conformations and Epigenomics Chachrit Khunsriraksakul, Daniel McGuire, Renan Sauteraud, Fang Chen, Lina yang, Rosa Kim, Jordan Hughey, Scott Eckert, J. Dylan Weissenkampen, Dajiang J. Liu
Camila Lopes-Ramos	33. Regulatory networks of liver carcinoma reveal sex-specific patterns of gene regulation Camila M. Lopes-Ramos, Marieke L. Kuijjer, Kimberly Glass, Dawn L. DeMeo, John Quackenbush
Sinha Rileen	34. Multi-omics Verification of Patient-Derived Tumor Models Rileen Sinha, Amir Vajdi Hoojghan, Elizabeth Cohen, Aniket Shetty, Smitha Yerrum, Kin-Hoe Chow, Keith L Ligon, Michael Y. Tolstorukov

Presenter

Poster Number, Title, & Authors

Rupam Bhattacharyya

30. TransPRECISE: Proteomics-based Network Modeling of the Pan-cancer Patient and Cell Line Interactome

Rupam Bhattacharyya, University of Michigan; Min Jin Ha, The University of Texas MD Anderson Cancer Center; Qingzhi Liu, University of Michigan; Rehan Akbani, The University of Texas MD Anderson Cancer Center; Han Liang, The University of Texas MD Anderson Cancer Center; Veerabhadran Baladandayuthapani, University of Michigan.

Beverly Dosso

31. ELOVL SNPs impact response to PUFA-rich diets and patient outcomes in secondary analysis of OMEGA trial

Beverly Dosso, Susan Sergeant, D. Clark Files, Timothy D. Howard, Carl D. Langefeld, Floyd H. Chilton, and Elaheh Rahbar

Chachrit Khunsriraksakul

32. PUMICE- Prediction Using Models Informed by Chromatin conformations and Epigenomics

Chachrit Khunsriraksakul, Daniel McGuire, Renan Sauteraud, Fang Chen, Lina yang, Rosa Kim, Jordan Hughey, Scott Eckert, J. Dylan Weissenkampen, Dajiang J. Liu

Camila Lopes-Ramos

33. Regulatory networks of liver carcinoma reveal sex-specific patterns of gene regulation

Camila M. Lopes-Ramos, Marieke L. Kuijjer, Kimberly Glass, Dawn L. DeMeo, John Quackenbush

Sinha Rileen

34. Multi-omics Verification of Patient-Derived Tumor Models

Rileen Sinha, Amir Vajdi Hoojghan, Elizabeth Cohen, Aniket Shetty, Smitha Yerrum, Kin-Hoe Chow, Keith L Ligon, Michael Y. Tolstorukov

Session III: Polygenic scores for disease prevention and clinical action

Presenter	Poster Number, Title, & Authors
Sofía Aguilar Lacasaña	35. Polygenic Risk for ADHD and ASD and their relationship with cognitive measures in school children Sofía Aguilar-Lacasaña, Natalia Vilor-Tejedor, Philip Jansen, Mònica López-Vicente, Mariona Bustamante, Miguel Burgaleta, Jordi Sunyer, Silvia Alemany
James Fife	36. Assessing clinical risk using polygenic risk and monogenic variants James Fife, Christopher Cassa
Ruchi Chaudhary	37. High polygenic risk and strong recessive disease inheritance in a young-onset Parkinson’s disease cohort in India Ruchi Chaudhary
Patricia Genius	38. Differentially genetic susceptibility of Hippocampal Subfields Volumes: A Polygenic-wide Association Study Patricia Genius, Greg Operto, Tavia E. Evans, Carles Falcón, Carolina Minguillón, Karine Fauria, Hieab H. Adams, Roderic Guigó, Juan Domingo Gispert, Natalia Vilor-Tejedor, and for the ALFA study
Natalie Hasbani	39. Lifetime risk of coronary heart disease: American Heart Association’s Life’s Simple 7 lifestyle recommendations and polygenic risk Natalie R. Hasbani, Symen Ligthart, Michael R. Brown, Adam Heath, Allison Bebo, Kellan E. Ashley, Eric Boerwinkle, Alanna C. Morrison, Aaron Folsom, David Aguilar, Paul S. de Vries
Jie Huang	40. PAGEANT (Personal Analysis of GEnome and ANnotation Toolkit) Jie Huang, Dan King
Xiaoqi Li	41. Polygenic Risk Assessment: Genetics Supported Imaging Diagnosis for Parkinson’s Disease Xiaoqi Li, Miguel Renteria, Xianjun Dong
Fah Sathirapongsasuti	42. South Asian Patient Population Genetics Reveal Strong Founder Effects and High Rates of Homozygosity – New Resources for Precision Medicine Jeffrey D. Wall, J. Fah Sathirapongsasuti, Ravi Gupta*, Ramesh Menon, Saurabh Belsare, Sameer Phalke, Anamitra Barik, Rajesh Kumar Rai, Anu Mittal, John Fang, Deepak Tanneeru, Jacqueline Robinson, Ruchi Chaudhary, Christian Fuchsberger, Lukas Forer, Sebastian Schoenherr, Qixin Bei, Tushar Bhangale, Jennifer Tom, Radha Venkatesan, Wallace Wang, Asif Rasheed, Pui-Yan Kwok, Amit Khera, Lakshmi, Adam Butterworth, John Danesh, Arkasubhra Ghosh, Viswanathan Mohan, Partha P. Majumder, Danish Saleheen, Abhijit Chowdhury, Sekar Seshagiri, Eric Stawiski, Andrew Peterson
Magdalena Sevilla-Gonzales	43. Effect of fasting insulin-associated gene variant clusters on cardiometabolic outcomes Magdalena Sevilla-Gonzalez, Hyunkyung Kim, Sarah Hsu, Jordi Merino, James B. Meigs, Jerome Rotter, Mark O. Goodarzi, Alisa K. Manning, Miriam Udler
Sarah Urbut	44. Understanding the Genetic Effects on Multivariate Lipid Phenotypes: An exploration of the Million Veterans Project Resource Sarah Urbut, S.Margaret Sunitha, Akhil Pampana, Lily Dattillo, Ben Neale, Chris O’Donnell, Gina Peloso, Pradeep Natarajan
Zhi Yu	45. Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases: the Atherosclerosis Risk in Communities Study Zhi Yu, Jin Jin, Adrienne Tin, Anna Köttgen, Bing Yu, Jingsha Chen, Aditya Surapaneni, Linda Zhou, Christie M. Ballantyne, Ron C. Hoogeveen, Dan E. Arking, Nilanjan Chatterjee, Morgan E. Grams, Josef Coresh
Zijie Zhao	46. Robust fine-tuning of diverse polygenic risk score models using GWAS summary statistics Zijie Zhao; Yanyao Yi; Jie Song; Yuchang Wu; Xiaoyuan Zhong; Yupei Lin; Timothy J. Hohman; Jason Fletcher; Qiongshi Lu

Presenter

Poster Number, Title, & Authors

Sofía Aguilar Lacasaña

35. Polygenic Risk for ADHD and ASD and their relationship with cognitive measures in school children

Sofía Aguilar-Lacasaña, Natalia Vilor-Tejedor, Philip Jansen, Mònica López-Vicente, Mariona Bustamante, Miguel Burgaleta, Jordi Sunyer, Silvia Alemany

James Fife

36. Assessing clinical risk using polygenic risk and monogenic variants

James Fife, Christopher Cassa

Ruchi Chaudhary

37. High polygenic risk and strong recessive disease inheritance in a young-onset Parkinson’s disease cohort in India

Ruchi Chaudhary

Patricia Genius

38. Differentially genetic susceptibility of Hippocampal Subfields Volumes: A Polygenic-wide Association Study

Patricia Genius, Greg Operto, Tavia E. Evans, Carles Falcón, Carolina Minguillón, Karine Fauria, Hieab H. Adams, Roderic Guigó, Juan Domingo Gispert, Natalia Vilor-Tejedor, and for the ALFA study

Natalie Hasbani

39. Lifetime risk of coronary heart disease: American Heart Association’s Life’s Simple 7 lifestyle recommendations and polygenic risk

Natalie R. Hasbani, Symen Ligthart, Michael R. Brown, Adam Heath, Allison Bebo, Kellan E. Ashley, Eric Boerwinkle, Alanna C. Morrison, Aaron Folsom, David Aguilar, Paul S. de Vries

Jie Huang

40. PAGEANT (Personal Analysis of GEnome and ANnotation Toolkit)

Jie Huang, Dan King

Xiaoqi Li

41. Polygenic Risk Assessment: Genetics Supported Imaging Diagnosis for Parkinson’s Disease

Xiaoqi Li, Miguel Renteria, Xianjun Dong

Fah Sathirapongsasuti

42. South Asian Patient Population Genetics Reveal Strong Founder Effects and High Rates of Homozygosity – New Resources for Precision Medicine

Jeffrey D. Wall*, J. Fah Sathirapongsasuti*, Ravi Gupta*, Ramesh Menon, Saurabh Belsare, Sameer Phalke, Anamitra Barik, Rajesh Kumar Rai, Anu Mittal, John Fang, Deepak Tanneeru, Jacqueline Robinson, Ruchi Chaudhary, Christian Fuchsberger, Lukas Forer, Sebastian Schoenherr, Qixin Bei, Tushar Bhangale, Jennifer Tom, Radha Venkatesan, Wallace Wang, Asif Rasheed, Pui-Yan Kwok, Amit Khera, Lakshmi, Adam Butterworth, John Danesh, Arkasubhra Ghosh, Viswanathan Mohan, Partha P. Majumder, Danish Saleheen, Abhijit Chowdhury, Sekar Seshagiri, Eric Stawiski, Andrew Peterson

Magdalena Sevilla-Gonzales

43. Effect of fasting insulin-associated gene variant clusters on cardiometabolic outcomes

Magdalena Sevilla-Gonzalez, Hyunkyung Kim, Sarah Hsu, Jordi Merino, James B. Meigs, Jerome Rotter, Mark O. Goodarzi, Alisa K. Manning, Miriam Udler

Sarah Urbut

44. Understanding the Genetic Effects on Multivariate Lipid Phenotypes: An exploration of the Million Veterans Project Resource

Sarah Urbut, S.Margaret Sunitha, Akhil Pampana, Lily Dattillo, Ben Neale, Chris O’Donnell, Gina Peloso, Pradeep Natarajan

Zhi Yu

45. Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases: the Atherosclerosis Risk in Communities Study

Zhi Yu, Jin Jin, Adrienne Tin, Anna Köttgen, Bing Yu, Jingsha Chen, Aditya Surapaneni, Linda Zhou, Christie M. Ballantyne, Ron C. Hoogeveen, Dan E. Arking, Nilanjan Chatterjee, Morgan E. Grams, Josef Coresh

Zijie Zhao

46. Robust fine-tuning of diverse polygenic risk score models using GWAS summary statistics

Zijie Zhao; Yanyao Yi; Jie Song; Yuchang Wu; Xiaoyuan Zhong; Yupei Lin; Timothy J. Hohman; Jason Fletcher; Qiongshi Lu