Session I: Therapeutic applications of genome editing
| Presenter | Title & Authors |
| Ramin Ardalani
|
CRISPR gene editing coupled with pre-implantation genetic testing: A promising procedure to reduce the risk of passing on genetic defects
Ramin Ardalani, Mohammad Reza Zabihi, Zahra Salehi |
| Anastasia Kaufman
|
The Pin-point™ base editing system – a modular, safe and highly precise gene editing platform for clinical applications
Immacolata Porreca, Bronwyn Joubert, Jennifer Harbottle, Robert Blassberg, Olga Mielczarek, Anastasia Lomova Kaufman, Kevin Hemphill, Jesse Stombaugh, Michael Rushton, Žaklina Strezoska, John Lambourne, Anja van Brabant Smith |
| Srishti Sahu
|
Peptide-enabled CRISPR enzyme delivery for versatile ex vivo T cell engineering Srishti Sahu, Dana Foss, David Nguyen, Daniel Carr, Joseph Muldoon, Justin Eyquem, Alexander Marson, Ross Wilson |
Session II: Discovery applications
| Presenter & Slack Link | Title & Authors |
| Sara Urbut
|
Dynamic Importance of Genomic and Nongenomic Risk Factors on Development of Ischemic Heart Disease
Sarah Urbut, Akl Fahed, Alexander Gusev, Pradeep Natarajan |
| Julian Willett
|
Colocalization of expression transcripts with COVID-19 outcomes is dependent on cell-type and cell-state
Julian Daniel Sunday Willett, Tianyuan Lu, Tomoko Nakanishi, Satoshi Yoshiji, Guillaume Butler-Laporte, Vincent Mooser, Sirui Zhou, Yossi Farjoun, J. Brent Richards |
Session III: Emerging challenges and technologies
| Presenter | Title & Authors |
| Evelyn Chen
|
Decorating chromatin for enhanced genome editing using CRISPR-Cas9
Evelyn Chen, Enrique Lin-Shiao, Marena Trinidad, Mohammad Saffari Doost, David Colognori, and Jennifer A. Doudna |
| Xiaolong Cheng
|
Modeling CRISPR-Cas13d on-target and off-target effects using machine learning approaches
Xiaolong Cheng, Zexu Li, Teng Fei, Wei Li |
| Roman Doll
|
Base editing in Drosophila highlights constraints on efficiency and product purity of cytidine deaminases
Roman M. Doll, Michael Boutros, Fillip Port |
| Vidur Kailash
|
Profiling Mitochondrial DNA Variants from Single-Cell DNA Sequencing
Vidur Kailash, Larry Reser, Yong Qian, Mary Kaileh, Jun Ding, and Luigi Ferrucci |
| Bumjun Kim
|
Development and optimizaiton of next-generation lipid nanoparticles for T cell transfection
Bumjun Kim and Prof. Robert Prud’homme |
| Edward Koh
|
Cas12i2v, a Novel Engineered High Efficiency Type V CRISPR System for Gene Editing
Edward Koh and Malini Varadarajan |
| Wei Li
|
Intrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems
Zexu Li1,2,#, Zihan Li, Xiaolong Cheng, Xiaofeng Wang, Shixin Ma, Shengnan Wang, Zhiyan Lu, Han Zhang, Wenchang Zhao, Zhisong Chen, Yingjia Yao, Lumen Chao, Wei Li, Teng Fei |
| Roy Rabinowitz
|
Engineering of Novel SpyCas9 High-Fidelity Variants using Entropy-based Computational Directed Evolution
Roy Rabinowitz, Oded Shor, Shay Herman, Natalie Zelikson, Shreyas Mediwale, Felix Benninger, Dani Offen |
| Jayoung Ryu
|
Accurate and high-throughput identification of causal variants of cellular LDL uptake via Bayesian network inference of CRISPR base editor reporter screens
Jayoung Ryu, Sam Barkal, Tian Yu, Luca Pinello, Richard Sherwood |
