Fellow or Post Doc

Aaron M Hosios

Postdoctoral Fellow

Molecular Metabolism

ahosios@hsph.harvard.edu

Other Positions

Teaching Assistant in Molecular and Cellular Biology

MCB

Faculty of Arts & Sciences

Links

Catalyst Profile

Bibliography

Author Correction: Cooperative nutrient accumulation sustains growth of mammalian cells.

Son S, Stevens MM, Chao HX, Thoreen C, Hosios AM, Schweitzer LD, Weng Y, Wood K, Sabatini D, Vander Heiden MG, Manalis S.

Sci Rep. 2020 Jul 21. 10(1):12054. PMID: 32694612

Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer.

Luengo A, Abbott KL, Davidson SM, Hosios AM, Faubert B, Chan SH, Freinkman E, Zacharias LG, Mathews TP, Clish CB, DeBerardinis RJ, Lewis CA, Vander Heiden MG.

Nat Commun. 2019 12 06. 10(1):5604. PMID: 31811141

Cancer-associated mutations in human pyruvate kinase M2 impair enzyme activity.

Liu VM, Howell AJ, Hosios AM, Li Z, Israelsen WJ, Vander Heiden MG.

FEBS Lett. 2020 02. 594(4):646-664. PMID: 31642061

Lack of evidence for substrate channeling or flux between wildtype and mutant isocitrate dehydrogenase to produce the oncometabolite 2-hydroxyglutarate.

Dexter JP, Ward PS, Dasgupta T, Hosios AM, Gunawardena J, Vander Heiden MG.

J Biol Chem. 2018 12 28. 293(52):20051-20061. PMID: 30381394

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth.

Cox AG, Tsomides A, Yimlamai D, Hwang KL, Miesfeld J, Galli GG, Fowl BH, Fort M, Ma KY, Sullivan MR, Hosios AM, Snay E, Yuan M, Brown KK, Lien EC, Chhangawala S, Steinhauser ML, Asara JM, Houvras Y, Link B, Vander Heiden MG, Camargo FD, Goessling W.

EMBO J. 2018 11 15. 37(22). PMID: 30348863