Alexander Fischer

TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality.

Sass F, Schlein C, Jaeckstein MY, Pertzborn P, Schweizer M, Schinke T, Ballabio A, Scheja L, Heeren J, Fischer AW.

Mol Metab. 2021 May. 47:101173. PMID: 33516944

Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.

Schlein C, Fischer AW, Sass F, Worthmann A, Tödter K, Jaeckstein MY, Behrens J, Lynes MD, Kiebish MA, Narain NR, Bussberg V, Darkwah A, Jespersen NZ, Nielsen S, Scheele C, Schweizer M, Braren I, Bartelt A, Tseng YH, Heeren J, Scheja L.

Cell Rep. 2021 01 12. 34(2):108624. PMID: 33440156

Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation.

Fischer AW, Jaeckstein MY, Gottschling K, Heine M, Sass F, Mangels N, Schlein C, Worthmann A, Bruns OT, Yuan Y, Zhu H, Chen O, Ittrich H, Nilsson SK, Stefanicka P, Ukropec J, Balaz M, Dong H, Sun W, Reimer R, Scheja L, Heeren J.

Cell Metab. 2021 Mar 02. 33(3):547-564.e7. PMID: 33357458

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.

Chitraju C, Fischer AW, Farese RV, Walther TC.

Cell Rep. 2020 11 03. 33(5):108348. PMID: 33147469

Thermoneutrality-Induced Macrophage Accumulation in Brown Adipose Tissue Does Not Impair the Tissue's Competence for Cold-Induced Thermogenic Recruitment.

Fischer AW, de Jong JMA, Sass F, Schlein C, Heeren J, Petrovic N.

Front Endocrinol (Lausanne). 2020. 11:568682. PMID: 33193086

CD38 downregulation modulates NAD+ and NADP(H) levels in thermogenic adipose tissues.

Benzi A, Sturla L, Heine M, Fischer AW, Spinelli S, Magnone M, Sociali G, Parodi A, Fenoglio D, Emionite L, Koch-Nolte F, Mittrücker HW, Guse AH, De Flora A, Zocchi E, Heeren J, Bruzzone S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2021 01. 1866(1):158819. PMID: 33010451

Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice.

Fischer AW, Behrens J, Sass F, Schlein C, Heine M, Pertzborn P, Scheja L, Heeren J.

J Lipid Res. 2020 11. 61(11):1377-1389. PMID: 32769145

Human brown adipose tissue: Classical brown rather than brite/beige?

Cannon B, de Jong JMA, Fischer AW, Nedergaard J, Petrovic N.

Exp Physiol. 2020 08. 105(8):1191-1200. PMID: 32378255

Leptin: Is It Thermogenic?

Fischer AW, Cannon B, Nedergaard J.

Endocr Rev. 2020 04 01. 41(2). PMID: 31774114

No insulating effect of obesity, neither in mice nor in humans.

Fischer AW, Cannon B, Nedergaard J.

Am J Physiol Endocrinol Metab. 2019 11 01. 317(5):E952-E953. PMID: 31697209