Alexander Gusev

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1.

Restuadi R, Steyn FJ, Kabashi E, Ngo ST, Cheng FF, Nabais MF, Thompson MJ, Qi T, Wu Y, Henders AK, Wallace L, Bye CR, Turner BJ, Ziser L, Mathers S, McCombe PA, Needham M, Schultz D, Kiernan MC, van Rheenen W, van den Berg LH, Veldink JH, Ophoff R, Gusev A, Zaitlen N, McRae AF, Henderson RD, Wray NR, Giacomotto J, Garton FC.

Genome Med. 2022 Jan 19. 14(1):7. PMID: 35042540

Association of Cutaneous Immune-Related Adverse Events With Increased Survival in Patients Treated With Anti-Programmed Cell Death 1 and Anti-Programmed Cell Death Ligand 1 Therapy.

Tang K, Seo J, Tiu BC, Le TK, Pahalyants V, Raval NS, Ugwu-Dike PO, Zubiri L, Naranbhai V, Carrington M, Gusev A, Reynolds KL, LeBoeuf NR, Asgari MM, Kwatra SG, Semenov YR.

JAMA Dermatol. 2022 Jan 12. PMID: 35019948

Artificial intelligence-aided clinical annotation of a large multi-cancer genomic dataset.

Kehl KL, Xu W, Gusev A, Bakouny Z, Choueiri TK, Riaz IB, Elmarakeby H, Van Allen EM, Schrag D.

Nat Commun. 2021 12 15. 12(1):7304. PMID: 34911934

HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study.

Naranbhai V, Viard M, Dean M, Groha S, Braun DA, Labaki C, Shukla SA, Yuki Y, Shah P, Chin K, Wind-Rotolo M, Mu XJ, Robbins PB, Gusev A, Choueiri TK, Gulley JL, Carrington M.

Lancet Oncol. 2022 Jan. 23(1):172-184. PMID: 34895481

H3K27ac HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility.

Giambartolomei C, Seo JH, Schwarz T, Freund MK, Johnson RD, Spisak S, Baca SC, Gusev A, Mancuso N, Pasaniuc B, Freedman ML.

Am J Hum Genet. 2021 12 02. 108(12):2284-2300. PMID: 34822763

Germline Testing Data Validate Inferences of Mutational Status for Variants Detected From Tumor-Only Sequencing.

Jalloul N, Gomy I, Stokes S, Gusev A, Johnson BE, Lindeman NI, Macconaill L, Ganesan S, Garber JE, Khiabanian H.

JCO Precis Oncol. 2021. 5. PMID: 34820595

Constructing germline research cohorts from the discarded reads of clinical tumor sequences.

Gusev A, Groha S, Taraszka K, Semenov YR, Zaitlen N.

Genome Med. 2021 11 08. 13(1):179. PMID: 34749793

Tumor Mutations Across Racial Groups in a Real-World Data Registry.

Kamran SC, Xie J, Cheung ATM, Mavura MY, Song H, Palapattu EL, Madej J, Gusev A, Van Allen EM, Huang FW.

JCO Precis Oncol. 2021 Nov. 5:1654-1658. PMID: 34994651

Allele-specific epigenetic activity in prostate cancer and normal prostate tissue implicates prostate cancer risk mechanisms.

Shetty A, Seo JH, Bell CA, O'Connor EP, Pomerantz MM, Freedman ML, Gusev A.

Am J Hum Genet. 2021 11 04. 108(11):2071-2085. PMID: 34699744

Immunotherapy-Mediated Thyroid Dysfunction: Genetic Risk and Impact on Outcomes with PD-1 Blockade in Non-Small Cell Lung Cancer.

Luo J, Martucci VL, Quandt Z, Groha S, Murray MH, Lovly CM, Rizvi H, Egger JV, Plodkowski AJ, Abu-Akeel M, Schulze I, Merghoub T, Cardenas E, Huntsman S, Li M, Hu D, Gubens MA, Gusev A, Aldrich MC, Hellmann MD, Ziv E.

Clin Cancer Res. 2021 09 15. 27(18):5131-5140. PMID: 34244291