Alexander Gusev

Germline predisposition to pediatric Ewing sarcoma is characterized by inherited pathogenic variants in DNA damage repair genes.

Gillani R, Camp SY, Han S, Jones JK, Chu H, O'Brien S, Young EL, Hayes L, Mitchell G, Fowler T, Gusev A, Kamihara J, Janeway KA, Schiffman JD, Crompton BD, AlDubayan SH, Van Allen EM.

Am J Hum Genet. 2022 Apr 29. PMID: 35512711

Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology.

Adib E, Nassar AH, Abou Alaiwi S, Groha S, Akl EW, Sholl LM, Michael KS, Awad MM, J?nne PA, Gusev A, Kwiatkowski DJ.

Genome Med. 2022 Apr 15. 14(1):39. PMID: 35428358

Pre-Existing Autoimmune Disease and Mortality in Patients Treated With Anti-PD-1 and Anti-PD-L1 Therapy.

Tang K, Tiu BC, Wan G, Zhang S, Nguyen N, Leung B, Gusev A, Reynolds KL, Kwatra SG, Semenov YR.

J Natl Cancer Inst. 2022 Feb 21. PMID: 35188215

Somatic mutational profiles and germline polygenic risk scores in human cancer.

Liu Y, Gusev A, Heng YJ, Alexandrov LB, Kraft P.

Genome Med. 2022 02 11. 14(1):14. PMID: 35144655

Association of Cutaneous Immune-Related Adverse Events With Increased Survival in Patients Treated With Anti-Programmed Cell Death 1 and Anti-Programmed Cell Death Ligand 1 Therapy.

Tang K, Seo J, Tiu BC, Le TK, Pahalyants V, Raval NS, Ugwu-Dike PO, Zubiri L, Naranbhai V, Carrington M, Gusev A, Reynolds KL, LeBoeuf NR, Asgari MM, Kwatra SG, Semenov YR.

JAMA Dermatol. 2022 Feb 01. 158(2):189-193. PMID: 35019948

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1.

Restuadi R, Steyn FJ, Kabashi E, Ngo ST, Cheng FF, Nabais MF, Thompson MJ, Qi T, Wu Y, Henders AK, Wallace L, Bye CR, Turner BJ, Ziser L, Mathers S, McCombe PA, Needham M, Schultz D, Kiernan MC, van Rheenen W, van den Berg LH, Veldink JH, Ophoff R, Gusev A, Zaitlen N, McRae AF, Henderson RD, Wray NR, Giacomotto J, Garton FC.

Genome Med. 2022 01 19. 14(1):7. PMID: 35042540

Artificial intelligence-aided clinical annotation of a large multi-cancer genomic dataset.

Kehl KL, Xu W, Gusev A, Bakouny Z, Choueiri TK, Riaz IB, Elmarakeby H, Van Allen EM, Schrag D.

Nat Commun. 2021 12 15. 12(1):7304. PMID: 34911934

HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study.

Naranbhai V, Viard M, Dean M, Groha S, Braun DA, Labaki C, Shukla SA, Yuki Y, Shah P, Chin K, Wind-Rotolo M, Mu XJ, Robbins PB, Gusev A, Choueiri TK, Gulley JL, Carrington M.

Lancet Oncol. 2022 01. 23(1):172-184. PMID: 34895481

H3K27ac HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility.

Giambartolomei C, Seo JH, Schwarz T, Freund MK, Johnson RD, Spisak S, Baca SC, Gusev A, Mancuso N, Pasaniuc B, Freedman ML.

Am J Hum Genet. 2021 12 02. 108(12):2284-2300. PMID: 34822763

Germline Testing Data Validate Inferences of Mutational Status for Variants Detected From Tumor-Only Sequencing.

Jalloul N, Gomy I, Stokes S, Gusev A, Johnson BE, Lindeman NI, Macconaill L, Ganesan S, Garber JE, Khiabanian H.

JCO Precis Oncol. 2021. 5. PMID: 34820595