Cleavage-defective Topoisomerase I mutants sharply increase G-quadruplex-associated genomic instability.
Berroyer A, Bacolla A, Tainer JA, Kim N.
Microb Cell. 2022 Mar 07. 9(3):52-68. PMID: 35291312
Research Fellows
Alexandra Berroyer
Other Positions
Postdoctoral Research Fellow
Environmental Health
Harvard T.H. Chan School of Public Health
Links
Bibliography
The activity of yeast Apn2 AP endonuclease at uracil-derived AP sites is dependent on the major carbon source.
Stokdyk K, Berroyer A, Grami ZA, Kim N.
Curr Genet. 2021 Apr. 67(2):283-294. PMID: 33386486
Yeast Nucleolin Nsr1 Impedes Replication and Elevates Genome Instability at an Actively Transcribed Guanine-Rich G4 DNA-Forming Sequence.
Singh S, Berroyer A, Kim M, Kim N.
Genetics. 2020 12. 216(4):1023-1037. PMID: 33106247
Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop 'G4 Kissing' interaction.
Williams JD, Houserova D, Johnson BR, Dyniewski B, Berroyer A, French H, Barchie AA, Bilbrey DD, Demeis JD, Ghee KR, Hughes AG, Kreitz NW, McInnis CH, Pudner SC, Reeves MN, Stahly AN, Turcu A, Watters BC, Daly GT, Langley RJ, Gillespie MN, Prakash A, Larson ED, Kasukurthi MV, Huang J, Jinks-Robertson S, Borchert GM.
Nucleic Acids Res. 2020 06 19. 48(11):5907-5925. PMID: 32383760
The Functional Consequences of Eukaryotic Topoisomerase 1 Interaction with G-Quadruplex DNA.
Berroyer A, Kim N.
Genes (Basel). 2020 02 12. 11(2). PMID: 32059547
Response of Sulfolobus solfataricus Dpo4 polymerase in vitro to a DNA G-quadruplex.
Berroyer A, Alvarado G, Larson ED.
Mutagenesis. 2019 09 20. 34(3):289-297. PMID: 31169295
Sites of instability in the human TCF3 (E2A) gene adopt G-quadruplex DNA structures in vitro.
Williams JD, Fleetwood S, Berroyer A, Kim N, Larson ED.
Front Genet. 2015. 6:177. PMID: 26029241