Ana Arruda

Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism.

Tirosh A, Tuncman G, Calay ES, Rathaus M, Ron I, Tirosh A, Yalcin A, Lee YG, Livne R, Ron S, Minsky N, Arruda AP, Hotamisligil GS.

Cell Metab. 2021 02 02. 33(2):319-333.e6. PMID: 33340456

Herbal medications for anxiety, depression, pain, nausea and vomiting related to preoperative surgical patients: a systematic review and meta-analysis of randomised controlled trials.

Arruda APN, Zhang Y, Gomaa H, Bergamaschi CC, Guimaraes CC, Righesso LAR, Paglia MDG, Barberato-Filho S, Lopes LC, Ayala Melendez AP, de Oliveira LD, Paula-Ramos L, Johnston B, El Dib R.

BMJ Open. 2019 05 24. 9(5):e023729. PMID: 31129571

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

Bartelt A, Widenmaier SB, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakgül G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, Tseng YH, Inouye KE, Arruda AP, Hotamisligil GS.

Nat Med. 2018 03. 24(3):292-303. PMID: 29400713

Defective STIM-mediated store operated Ca2+ entry in hepatocytes leads to metabolic dysfunction in obesity.

Arruda AP, Pers BM, Parlakgul G, Güney E, Goh T, Cagampan E, Lee GY, Goncalves RL, Hotamisligil GS.

Elife. 2017 12 15. 6. PMID: 29243589

NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis.

Widenmaier SB, Snyder NA, Nguyen TB, Arduini A, Lee GY, Arruda AP, Saksi J, Bartelt A, Hotamisligil GS.

Cell. 2017 Nov 16. 171(5):1094-1109.e15. PMID: 29149604

Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.

Charles KN, Li MD, Engin F, Arruda AP, Inouye K, Hotamisligil GS.

Cell Rep. 2017 Oct 10. 21(2):393-402. PMID: 29020626

Herbal medications for surgical patients: a systematic review protocol.

Arruda APN, Ayala AP, Lopes LC, Bergamaschi CC, Guimarães C, Grossi MD, Righesso LAR, Agarwal A, El Dib R.

BMJ Open. 2017 07 26. 7(7):e014290. PMID: 28751485

Deletion of tumor necrosis factor-a receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis.

Romanatto T, Roman EA, Arruda AP, Denis RG, Solon C, Milanski M, Moraes JC, Bonfleur ML, Degasperi GR, Picardi PK, Hirabara S, Boschero AC, Curi R, Velloso LA.

J Biol Chem. 2016 12 23. 291(52):26934. PMID: 28011876

Chaperone insufficiency links TLR4 signaling to endoplasmic reticulum stress.

Coope A, Milanski M, Arruda AP, Ignacio-Souza LM, Saad MJ, Anhê GF, Velloso LA.

J Biol Chem. 2016 12 23. 291(52):26936. PMID: 28011878

Calcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes.

Arruda AP, Hotamisligil GS.

Cell Metab. 2015 Sep 01. 22(3):381-97. PMID: 26190652