Angela M Early

Breadth of humoral immune responses to the C-terminus of the circumsporozoite protein is associated with protective efficacy induced by the RTS,S malaria vaccine.

Chaudhury S, MacGill RS, Early AM, Bolton JS, King CR, Locke E, Pierson T, Wirth DF, Neafsey DE, Bergmann-Leitner ES.

Vaccine. 2021 Feb 05. 39(6):968-975. PMID: 33431225

Population genomics of Plasmodium vivax in Panama to assess the risk of case importation on malaria elimination.

Buyon LE, Santamaria AM, Early AM, Quijada M, Barahona I, Lasso J, Avila M, Volkman SK, Marti M, Neafsey DE, Obaldia Iii N.

PLoS Negl Trop Dis. 2020 12. 14(12):e0008962. PMID: 33315861

Population genomics reveals the expansion of highly inbred Plasmodium vivax lineages in the main malaria hotspot of Brazil.

de Oliveira TC, Corder RM, Early A, Rodrigues PT, Ladeia-Andrade S, Alves JMP, Neafsey DE, Ferreira MU.

PLoS Negl Trop Dis. 2020 10. 14(10):e0008808. PMID: 33112884

Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance.

Mathieu LC, Cox H, Early AM, Mok S, Lazrek Y, Paquet JC, Ade MP, Lucchi NW, Grant Q, Udhayakumar V, Alexandre JS, Demar M, Ringwald P, Neafsey DE, Fidock DA, Musset L.

Elife. 2020 05 12. 9. PMID: 32394893

Amplicon deep sequencing of kelch13 in Plasmodium falciparum isolates from Senegal.

Gaye A, Sy M, Ndiaye T, Siddle KJ, Park DJ, Deme AB, Mbaye A, Dieye B, Ndiaye YD, Neafsey DE, Early A, Farrell T, Yade MS, Diallo MA, Diongue K, Bei A, Ndiaye IM, Volkman SK, Badiane AS, Ndiaye D.

Malar J. 2020 Mar 30. 19(1):134. PMID: 32228566

Detection of low-density Plasmodium falciparum infections using amplicon deep sequencing.

Early AM, Daniels RF, Farrell TM, Grimsby J, Volkman SK, Wirth DF, MacInnis BL, Neafsey DE.

Malar J. 2019 Jul 01. 18(1):219. PMID: 31262308

Naturally acquired immunity against immature Plasmodium falciparum gametocytes.

Dantzler KW, Ma S, Ngotho P, Stone WJR, Tao D, Rijpma S, De Niz M, Nilsson Bark SK, Jore MM, Raaijmakers TK, Early AM, Ubaida-Mohien C, Lemgruber L, Campo JJ, Teng AA, Le TQ, Walker CL, Hermand P, Deterre P, Davies DH, Felgner P, Morlais I, Wirth DF, Neafsey DE, Dinglasan RR, Laufer M, Huttenhower C, Seydel K, Taylor T, Bousema T, Marti M.

Sci Transl Med. 2019 06 05. 11(495). PMID: 31167926

Mutations in Plasmodium falciparum actin-binding protein coronin confer reduced artemisinin susceptibility.

Demas AR, Sharma AI, Wong W, Early AM, Redmond S, Bopp S, Neafsey DE, Volkman SK, Hartl DL, Wirth DF.

Proc Natl Acad Sci U S A. 2018 12 11. 115(50):12799-12804. PMID: 30420498

Transmission of molecularly undetectable circulating parasite clones leads to high infection complexity in mosquitoes post feeding.

Grignard L, Gonçalves BP, Early AM, Daniels RF, Tiono AB, Guelbéogo WM, Ouédraogo A, van Veen EM, Lanke K, Diarra A, Nebie I, Sirima SB, Targett GA, Volkman SK, Neafsey DE, Wirth DF, Bousema T, Drakeley C.

Int J Parasitol. 2018 07. 48(8):671-677. PMID: 29738740

Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections.

Early AM, Lievens M, MacInnis BL, Ockenhouse CF, Volkman SK, Adjei S, Agbenyega T, Ansong D, Gondi S, Greenwood B, Hamel M, Odero C, Otieno K, Otieno W, Owusu-Agyei S, Asante KP, Sorgho H, Tina L, Tinto H, Valea I, Wirth DF, Neafsey DE.

Nat Commun. 2018 04 11. 9(1):1381. PMID: 29643376