Carlos G. Silva Garcia
Fellow or Post Doc

Carlos G. Silva Garcia

Postdoctoral Research Fellow

Molecular Metabolism

cgsilva@hsph.harvard.edu


Overview

My broad scientific interests lie in understanding genetic and non-genetic mechanisms that regulate aging and aging-related diseases. In particular, I am interested to study how molecular and cellular mechanisms of external signals that promote longevity regulate epigenetic and metabolic changes; how it impacts age-related diseases, and whether these conditions (positive or negative) can be transmitted to next generations. In the Mair lab, I study how epigenetic marks reprogram transcriptional networks to promote longevity using cutting-edge techniques such as CRISPR to develop novel approaches to study the aging process.


Bibliography

ARDD 2020: from aging mechanisms to interventions.

Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG, Georgievskaya A, Gladyshev VN, Glass DJ, Gorbunova V, de Grey A, He WW, Hoeijmakers J, Hoffmann E, Horvath S, Houtkooper RH, Jensen MK, Jensen MB, Kane A, Kassem M, de Keizer P, Kennedy B, Karsenty G, Lamming DW, Lee KF, MacAulay N, Mamoshina P, Mellon J, Molenaars M, Moskalev A, Mund A, Niedernhofer L, Osborne B, Pak HH, Parkhitko A, Raimundo N, Rando TA, Rasmussen LJ, Reis C, Riedel CG, Franco-Romero A, Schumacher B, Sinclair DA, Suh Y, Taub PR, Toiber D, Treebak JT, Valenzano DR, Verdin E, Vijg J, Young S, Zhang L, Bakula D, Zhavoronkov A, Scheibye-Knudsen M.

Aging (Albany NY). 2020 Dec 30. 12(24):24484-24503. PMID: 33378272